2IZV

crystal structure of socs-4 in complex with elongin-b and elongin-c at 2.55a resolution

• Total interactions analyzed: 3
• Total true interactions: 3
• Strongest Interaction:
  • Chains: B-C
  • Int. Res.: 95
  • Norm. En. per Res.: -4.5374
• Hub Node: A(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-4.1478	0.0	-44.1651	-48.3129	27	0	2	1958	0	1	2
A-C	-20.9779	-3.8124	-260.582	-285.3724	85	12	12	11028	0	6	3
B-C	-78.7694	-23.5115	-328.77	-431.0509	95	13	6	12557	1	24	24

Interface residues

• A-B: ALA408A, ASN399A, ASP101B, ASP404A, ASP407A, CYS393A, CYS398A, CYS400A, GLU98B, GLY405A, ILE397A, ILE406A, ILE411A, LEU409A, LEU419A, LEU99B, LYS104B, LYS416A, MET103B, PRO100B, PRO105B, PRO410A, PRO97B, THR401A, THR402A, VAL102B, VAL396A
• A-C: ALA100C, ALA106C, ALA107C, ALA408A, ALA96C, ARG383A, ARG394A, ARG82C, ASN108C, ASN282A, ASN283A, ASN284A, ASN399A, ASN85C, ASP111C, CYS112C, CYS286A, CYS393A, CYS398A, CYS400A, CYS74C, GLN280A, GLN390A, GLU102C, GLU89C, GLU92C, GLU98C, HIS391A, ILE382A, ILE392A, ILE397A, ILE406A, ILE411A, ILE90C, ILE95C, ILE99C, LEU101C, LEU103C, LEU104C, LEU110C, LEU279A, LEU389A, LEU409A, LEU419A, LEU70C, LYS416A, LYS72C, LYS80C, MET105C, MET415A, MET75C, PHE109C, PHE385A, PHE387A, PHE77C, PHE93C, PRO285A, PRO380A, PRO386A, PRO410A, PRO412A, PRO91C, PRO94C, PRO97C, SER388A, SER39C, SER413A, SER414A, SER86C, SER87C, THR384A, THR38C, THR395A, THR401A, THR78C, THR84C, THR88C, TYR418A, TYR76C, TYR79C, TYR83C, VAL396A, VAL69C, VAL73C, VAL81C
• B-C: ALA100C, ALA18B, ALA71B, ALA73B, ALA96C, ARG68B, ARG82C, ARG8B, ARG9B, ASP17B, ASP25C, ASP2B, CYS74C, GLN70B, GLU102C, GLU28C, GLU91B, GLU92C, GLU98B, GLU98C, GLY26C, GLY33B, HIS10B, HIS27C, HIS35C, HIS68C, ILE14B, ILE22C, ILE30B, ILE30C, ILE34B, ILE65C, ILE7B, ILE90B, ILE90C, ILE95C, ILE99C, LEU101C, LEU21C, LEU35B, LEU5B, LEU70C, LEU99B, LYS104B, LYS11B, LYS20C, LYS32C, LYS72C, LYS80C, MET103B, MET17C, MET1B, MET6B, MET75C, PHE15B, PHE29C, PHE4B, PHE77C, PHE93B, PHE93C, PRO100B, PRO105B, PRO66C, PRO69B, PRO72B, PRO91C, PRO92B, PRO94C, PRO96B, PRO97B, PRO97C, SER23C, SER24C, SER64B, SER67C, SER71C, SER94B, SER95B, THR12B, THR13B, THR16B, THR74B, THR78C, TYR18C, TYR76C, TYR79C, TYR83C, VAL102B, VAL19C, VAL31B, VAL31C, VAL3B, VAL69C, VAL73C, VAL81C