2IPH

x-ray structure at 1.75 a resolution of a norovirus protease linked to an active site directed peptide inhibitor

• Total interactions analyzed: 1
• Total true interactions: 1
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 85
  • Norm. En. per Res.: -2.7836
• Hub Node: A(1)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-40.1949	-1.0212	-195.391	-236.6071	85	5	12	8575	0	14	12

Interface residues

• A-B: ALA1001A, ALA1098A, ALA1125A, ALA1127A, ALA1148A, ALA2098B, ALA2125B, ALA2127B, ARG1089A, ARG1100A, ARG1147A, ARG2089B, ARG2100B, ASN1126A, ASN1165A, ASN2126B, ASN2165B, ASP1131A, ASP2131B, CYS1083A, CYS2083B, GLU1093A, GLU2093B, GLY1080A, GLY1092A, GLY1124A, GLY1129A, GLY1133A, GLY2092B, GLY2124B, GLY2129B, GLY2133B, ILE1087A, ILE2087B, LEU1005A, LEU1086A, LEU1094A, LEU1095A, LEU1097A, LEU1121A, LEU1122A, LEU1132A, LEU2005B, LEU2086B, LEU2094B, LEU2095B, LEU2097B, LEU2121B, LEU2122B, LEU2132B, LYS1128A, LYS1146A, LYS2088B, LYS2128B, LYS2146B, MET1120A, MET1130A, MET2130B, PRO1002A, PRO1003A, PRO1096A, PRO2096B, SER1084A, SER2007B, SER2084B, SER2091B, THR1081A, THR1123A, THR2004B, THR2081B, THR2123B, TRP1006A, TRP1151A, TRP2006B, TRP2151B, TYR1145A, TYR2145B, VAL1082A, VAL1085A, VAL1099A, VAL1144A, VAL2082B, VAL2085B, VAL2099B, VAL2144B