2INV

crystal structure of insulin fructotransferase in the presence of di- fructose

• Total interactions analyzed: 3
• Total true interactions: 3
• Strongest Interaction:
  • Chains: A-C
  • Int. Res.: 219
  • Norm. En. per Res.: -3.7173
• Hub Node: A(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-94.2501	-64.0577	-623.084	-781.3917	220	40	8	24343	9	50	52
A-C	-118.627	-65.5395	-629.927	-814.0935	219	47	8	24553	9	50	52
B-C	-112.4403	-68.9745	-626.041	-807.4559	219	40	8	24457	9	48	52

Interface residues

• A-B: ALA123A, ALA123B, ALA150B, ALA170A, ALA234A, ALA243B, ALA257A, ALA333A, ALA333B, ALA375B, ALA400A, ALA404A, ALA404B, ALA445A, ALA70B, ALA94A, ALA98A, ALA99A, ARG132B, ARG154B, ARG169A, ARG174A, ARG181A, ARG181B, ARG236A, ARG304A, ARG311B, ARG337B, ARG338B, ARG447A, ARG447B, ARG88A, ARG95A, ASN139B, ASN145B, ASN238A, ASN238B, ASN240B, ASN263B, ASN287B, ASN288B, ASN303A, ASN310A, ASN310B, ASN329A, ASN334A, ASN334B, ASN366A, ASN367A, ASN372A, ASN372B, ASN377B, ASN401A, ASN406A, ASN406B, ASN53A, ASP106B, ASP116A, ASP172A, ASP182A, ASP182B, ASP211A, ASP233A, ASP239A, ASP239B, ASP365A, ASP371A, ASP371B, ASP399A, ASP430A, ASP430B, ASP56B, ASP93A, CYS184B, CYS305A, GLN144B, GLN147B, GLN256A, GLN313B, GLN436B, GLN71B, GLN89A, GLU244B, GLU280A, GLU328A, GLY105B, GLY124B, GLY126B, GLY128B, GLY142B, GLY149B, GLY171A, GLY177A, GLY217B, GLY219B, GLY255A, GLY262B, GLY281A, GLY286A, GLY286B, GLY432B, GLY97A, HIS127B, HIS152B, HIS214A, HIS264B, HIS279A, HIS335B, HIS407B, HIS416B, HIS425A, ILE100A, ILE101A, ILE101B, ILE102B, ILE122A, ILE134B, ILE178A, ILE215A, ILE242B, ILE259A, ILE331A, ILE336B, ILE369A, ILE446A, ILE85A, LEU120A, LEU135B, LEU146B, LEU175A, LEU235A, LEU282A, LEU283A, LEU289B, LEU312B, LEU330A, LEU368A, LEU373B, LEU405A, LEU405B, LEU429A, LEU429B, LYS327A, LYS427A, LYS86A, PHE125B, PHE129B, PHE130B, PHE180A, PHE213A, PHE220B, PHE290B, PHE374B, PRO103B, PRO104B, PRO140B, PRO148B, PRO173A, PRO291B, PRO448A, PRO448B, PRO450A, PRO450B, PRO52A, PRO92A, PRO96A, SER118A, SER131B, SER138B, SER151B, SER176A, SER212A, SER261A, SER261B, SER306A, SER309A, SER309B, SER370A, SER370B, SER410B, SER426A, SER431B, SER91A, THR121A, THR141B, THR216A, THR216B, THR258A, THR285A, THR285B, THR308A, THR308B, THR332A, THR332B, THR339B, THR433B, THR444A, THR449B, THR54A, THR58B, THR59B, THR90A, TRP143B, TYR107B, TYR119A, TYR376B, TYR55A, VAL117A, VAL179A, VAL221B, VAL237A, VAL260A, VAL284A, VAL307A, VAL402A, VAL403A, VAL408B, VAL409B, VAL428A, VAL57B
• A-C: ALA123A, ALA123C, ALA150A, ALA170C, ALA234C, ALA243A, ALA257C, ALA333A, ALA333C, ALA375A, ALA400C, ALA404A, ALA404C, ALA445C, ALA70A, ALA94C, ALA98C, ALA99C, ARG132A, ARG154A, ARG169C, ARG174C, ARG181A, ARG181C, ARG236C, ARG304C, ARG311A, ARG337A, ARG338A, ARG447A, ARG447C, ARG88C, ARG95C, ASN139A, ASN145A, ASN238A, ASN238C, ASN240A, ASN263A, ASN287A, ASN288A, ASN303C, ASN310A, ASN310C, ASN329C, ASN334A, ASN334C, ASN366C, ASN367C, ASN372A, ASN372C, ASN377A, ASN401C, ASN406A, ASN406C, ASN53C, ASP106A, ASP116C, ASP172C, ASP182A, ASP182C, ASP211C, ASP233C, ASP239A, ASP239C, ASP365C, ASP371A, ASP371C, ASP399C, ASP430A, ASP430C, ASP56A, ASP93C, CYS184A, CYS305C, GLN144A, GLN147A, GLN256C, GLN313A, GLN436A, GLN71A, GLN89C, GLU244A, GLU280C, GLU328C, GLY105A, GLY124A, GLY126A, GLY128A, GLY142A, GLY149A, GLY171C, GLY177C, GLY217A, GLY219A, GLY255C, GLY262A, GLY281C, GLY286A, GLY286C, GLY432A, GLY97C, HIS127A, HIS152A, HIS214C, HIS264A, HIS279C, HIS335A, HIS407A, HIS416A, HIS425C, ILE100C, ILE101A, ILE101C, ILE102A, ILE122C, ILE134A, ILE178C, ILE215C, ILE242A, ILE259C, ILE331C, ILE336A, ILE369C, ILE446C, ILE85C, LEU120C, LEU135A, LEU146A, LEU175C, LEU235C, LEU282C, LEU283C, LEU289A, LEU312A, LEU330C, LEU368C, LEU373A, LEU405A, LEU405C, LEU429A, LEU429C, LYS327C, LYS427C, PHE125A, PHE129A, PHE130A, PHE180C, PHE213C, PHE220A, PHE290A, PHE374A, PRO103A, PRO104A, PRO140A, PRO148A, PRO173C, PRO291A, PRO448A, PRO448C, PRO450A, PRO450C, PRO52C, PRO92C, PRO96C, SER118C, SER131A, SER138A, SER151A, SER176C, SER212C, SER261A, SER261C, SER306C, SER309A, SER309C, SER370A, SER370C, SER410A, SER426C, SER431A, SER91C, THR121C, THR141A, THR216A, THR216C, THR258C, THR285A, THR285C, THR308A, THR308C, THR332A, THR332C, THR339A, THR433A, THR444C, THR449A, THR54C, THR58A, THR59A, THR90C, TRP143A, TYR107A, TYR119C, TYR376A, TYR55C, VAL117C, VAL179C, VAL221A, VAL237C, VAL260C, VAL284C, VAL307C, VAL402C, VAL403C, VAL408A, VAL409A, VAL428C, VAL57A
• B-C: ALA123B, ALA123C, ALA150C, ALA170B, ALA234B, ALA243C, ALA257B, ALA333B, ALA333C, ALA375C, ALA400B, ALA404B, ALA404C, ALA445B, ALA70C, ALA94B, ALA98B, ALA99B, ARG132C, ARG154C, ARG169B, ARG174B, ARG181B, ARG181C, ARG236B, ARG304B, ARG311C, ARG337C, ARG338C, ARG447B, ARG447C, ARG88B, ARG95B, ASN139C, ASN145C, ASN238B, ASN238C, ASN240C, ASN263C, ASN287C, ASN288C, ASN303B, ASN310B, ASN310C, ASN329B, ASN334B, ASN334C, ASN366B, ASN367B, ASN372B, ASN372C, ASN377C, ASN401B, ASN406B, ASN406C, ASN53B, ASP106C, ASP116B, ASP172B, ASP182B, ASP182C, ASP211B, ASP233B, ASP239B, ASP239C, ASP365B, ASP371B, ASP371C, ASP399B, ASP430B, ASP430C, ASP56C, ASP93B, CYS184C, CYS305B, GLN144C, GLN147C, GLN256B, GLN313C, GLN436C, GLN71C, GLN89B, GLU244C, GLU280B, GLU328B, GLY105C, GLY124C, GLY126C, GLY128C, GLY142C, GLY149C, GLY171B, GLY177B, GLY217C, GLY219C, GLY255B, GLY262C, GLY281B, GLY286B, GLY286C, GLY432C, GLY97B, HIS127C, HIS152C, HIS214B, HIS264C, HIS279B, HIS335C, HIS407C, HIS416C, HIS425B, ILE100B, ILE101B, ILE101C, ILE102C, ILE122B, ILE134C, ILE178B, ILE215B, ILE242C, ILE259B, ILE331B, ILE336C, ILE369B, ILE446B, ILE85B, LEU120B, LEU135C, LEU146C, LEU175B, LEU235B, LEU282B, LEU283B, LEU289C, LEU312C, LEU330B, LEU368B, LEU373C, LEU405B, LEU405C, LEU429B, LEU429C, LYS327B, LYS427B, LYS86B, PHE125C, PHE129C, PHE130C, PHE180B, PHE213B, PHE220C, PHE290C, PHE374C, PRO103C, PRO104C, PRO140C, PRO148C, PRO173B, PRO291C, PRO448B, PRO448C, PRO450B, PRO450C, PRO52B, PRO92B, PRO96B, SER118B, SER131C, SER138C, SER151C, SER176B, SER212B, SER261B, SER261C, SER306B, SER309B, SER309C, SER370B, SER370C, SER410C, SER426B, SER431C, SER91B, THR121B, THR141C, THR216B, THR216C, THR258B, THR285B, THR285C, THR308B, THR308C, THR332B, THR332C, THR339C, THR433C, THR449C, THR54B, THR58C, THR59C, THR90B, TRP143C, TYR107C, TYR119B, TYR376C, TYR55B, VAL117B, VAL179B, VAL221C, VAL237B, VAL260B, VAL284B, VAL307B, VAL402B, VAL403B, VAL408C, VAL409C, VAL428B, VAL57C