2IIP

human nicotinamide n-methyltransferase

• Total interactions analyzed: 6
• Total true interactions: 5
• Strongest Interaction:
  • Chains: B-D
  • Int. Res.: 57
  • Norm. En. per Res.: -2.7102
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	0.0	16.7918	-121.196	-104.4042	79	5	1	5151	1	25	33
A-C	0.0	0.0	-0.0148	-0.0148	2	0	0	4	0	1	1
A-D	-12.3291	3.9617	-122.493	-130.8605	49	5	7	4807	0	8	8
B-C	-11.1213	9.5307	-119.377	-120.9676	48	7	7	4677	0	7	7
B-D	-18.7581	-20.2369	-115.485	-154.48	57	11	0	5005	2	24	21

Interface residues

• A-B: ALA100B, ALA101B, ALA103A, ALA151B, ARG-2A, ARG18A, ASN16A, ASN90B, ASP142B, ASP19A, ASP88A, ASP88B, ASP9A, ASP9B, CB5.600022.45620, CYS141B, GLN137B, GLN145B, GLN147B, GLN209A, GLN89A, GLN89B, GLN92A, GLN92B, GLU208A, GLU22A, GLU93B, GLU95B, GLY-6A, GLY150B, GLY207A, HIS-9A, HIS-9A5, HIS14A, ILE206A, LEU-5A, LEU12A, LEU12B, LEU139B, LEU149B, LEU154B, LEU91B, LEU94B, LEU98B, LYS136B, LYS140B, LYS210A, LYS23A, LYS26A, LYS8B, LYS96A, LYS96B, LYS99B, MET205A, MET246A, PHE15A, PHE211A, PRO148B, PRO153B, PRO17A, SER-7A, SER-8A, SER13A, SER13B, SER146B, SER87A, SER87B, THR10A, THR144B, THR245A, TRP97B, TYR11A, TYR20A, TYR86B, VAL-4A, VAL135B, VAL138B, VAL152B, VAL82B
• A-C: GLU208C, LYS123A
• A-D: ALA220D, ALA223D, ALA224D, ALA228D, ARG178D, ARG181D, ARG218D, ASN248D, ASP172D, CB5.52603-15.25312, CYS177D, GLU219D, GLU222D, GLU227D, GLU250D, GLU2A, GLY-6A, GLY217D, GLY4A, HIS-9A, HIS-9A5, LEU-5A, LEU173D, LEU180D, LEU199D, LEU214D, LEU216D, LYS200D, LYS210A, LYS226D, MET1A, PHE5A, PHE5D, PRO-3A, PRO171D, PRO174D, PRO215D, SER-7A, SER-8A, SER0A, SER201D, SER202D, SER213D, SER3A, THR175D, TYR176D, VAL-4A, VAL221D, VAL225D
• B-C: ALA220C, ALA223C, ALA224C, ALA228C, ARG178C, ARG181C, ARG218C, ASN248C, ASN249C, ASP172C, CYS177C, GLU219C, GLU222C, GLU227C, GLU250C, GLU2B, GLY-6B, GLY217C, GLY4B, LEU-5B, LEU173C, LEU180C, LEU199C, LEU214C, LEU216C, LYS200C, LYS210B, LYS226C, MET1B, PHE5B, PHE5C, PRO-3B, PRO171C, PRO174C, PRO215C, SER-7B, SER-8B, SER0B, SER201C, SER202C, SER212B, SER213C, SER3B, THR175C, TYR176C, VAL-4B, VAL221C, VAL225C
• B-D: ALA100B, ALA101B, ALA103B, ALA104B, ALA134B, ALA169D, ALA179D, ALA224D, ALA228D, ARG132B, ARG178D, ARG181D, ASN182D, ASP142D, ASP172D, CYS170D, CYS177D, GLN133B, GLN145D, GLN147D, GLU126B, GLU128B, GLU129B, GLU227D, GLU80B, GLU95B, GLY124B, GLY229D, GLY4D, LEU131B, LEU173D, LEU98B, LYS123B, LYS127B, LYS130B, LYS136B, LYS79B, LYS8D, LYS96B, LYS99B, PHE5D, PRO102B, PRO125B, PRO171D, PRO174D, PRO189D, SER146D, SER7D, THR144D, THR175D, TRP2B, TRP97B, TYR176D, VAL122B, VAL135B, VAL138B, VAL143D