2IE3

structure of the protein phosphatase 2a core enzyme bound to tumor- inducing toxins

• Total interactions analyzed: 3
• Total true interactions: 2
• Strongest Interaction:
  • Chains: A-C
  • Int. Res.: 89
  • Norm. En. per Res.: -4.2342
• Hub Node: A(1)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-C	-93.2515	-49.7419	-233.846	-376.8394	89	18	3	9491	9	46	34
C-I	0.0	0.0	-27.5259	-27.5259	20	7	0	1406	0	3	4

Interface residues

• A-C: ALA292C, ALA415A, ALA457A, ALA534A, ARG106C, ARG108C, ARG110C, ARG418A, ARG420A, ARG459A, ARG498A, ARG49C, ARG537A, ARG70C, ASN494A, ASN535A, ASN539A, ASN79C, ASP11C, ASP279C, ASP280C, ASP290C, ASP453A, ASP492A, ASP531A, ASP570A, ASP572A, ASP574A, ASP64C, ASP77C, CYS50C, GLN272C, GLN288C, GLN571A, GLU109C, GLU277C, GLU460A, GLU581A, GLU67C, GLY72C, GLY73C, HIS454A, HIS497A, HIS63C, ILE111C, ILE458A, ILE71C, LEU278C, LEU287C, LEU421A, LEU496A, LEU68C, LYS283C, LYS416A, LYS542A, LYS74C, LYS8C, MET499A, MET66C, PHE286C, PHE289C, PHE503A, PHE538A, PHE578A, PHE69C, PRO291C, PRO293C, PRO493A, PRO51C, PRO532A, PRO76C, SER285C, SER75C, THR281C, THR53C, THR78C, THR7C, TRP417A, TYR107C, TYR456A, TYR495A, TYR577A, TYR80C, VAL455A, VAL52C, VAL533A, VAL536A, VAL573A, VAL575A
• C-I: ALA216C, ARG214C, ARG268C, ARG4I, ARG89C, ASN117C, ASP202C, CYS266C, CYS269C, GLY215C, HIS118C, HIS241C, LEU243C, LEU2I, PRO213C, SER212C, TRP200C, TYR127C, TYR265C, TYR267C