2ID5

crystal structure of the lingo-1 ectodomain

• Total interactions analyzed: 6
• Total true interactions: 4
• Strongest Interaction:
  • Chains: B-C
  • Int. Res.: 136
  • Norm. En. per Res.: -1.8317
• Hub Node: A(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-15.1387	14.9307	-238.692	-238.9	139	9	7	11363	3	25	24
A-D	-13.5129	47.4029	-224.592	-190.7019	124	8	7	10495	1	21	24
B-C	-18.7634	30.7135	-261.058	-249.1079	136	18	6	11978	0	20	26
C-D	-13.8089	13.3269	-251.785	-252.267	141	9	9	11676	1	24	25

Interface residues

• A-B: ALA147A, ALA171A, ALA291B, ALA385B, ALA416B, ALA460B, ALA461B, ALA463B, ALA53A, ALA70A, ARG146A, ARG198A, ARG201A, ARG293B, ARG337B, ARG343B, ARG344B, ARG345B, ARG347B, ARG384B, ARG390B, ARG423B, ASN105A, ASN129A, ASN138A, ASN152A, ASN163A, ASN187A, ASN296B, ASN321B, ASN378B, ASN462B, ASN466B, ASN77A, ASN78A, ASP121A, ASP126A, ASP139A, ASP373B, ASP467B, ASP50A, CYS162A, CYS336B, CYS382B, CYS458B, GLN125A, GLN49A, GLU288B, GLU312B, GLU313B, GLU72A, GLY102A, GLY150A, GLY265B, GLY294B, GLY320B, GLY464B, GLY465B, GLY74A, GLY98A, HIS145A, HIS174A, HIS176A, HIS269B, HIS317B, HIS425B, ILE118A, ILE143A, ILE387B, ILE459B, ILE95A, LEU103A, LEU119A, LEU120A, LEU127A, LEU140A, LEU151A, LEU164A, LEU175A, LEU272B, LEU295B, LEU322B, LEU339B, LEU375B, LEU376B, LEU418B, LEU420B, LEU426B, LEU457B, LEU94A, LEU97A, LYS424B, LYS430B, LYS93A, MET123A, MET469B, PHE124A, PHE148A, PHE316B, PHE342B, PHE380B, PHE80A, PRO289B, PRO377B, PRO422B, PRO470B, PRO73A, PRO96A, SER104A, SER144A, SER149A, SER153A, SER166A, SER173A, SER266B, SER314B, SER318B, SER421B, SER468B, SER69A, THR101A, THR165A, THR381B, TRP340B, TRP419B, TYR122A, TYR128A, TYR142A, TYR290B, TYR297B, TYR379B, VAL117A, VAL141A, VAL315B, VAL319B, VAL374B, VAL427B, VAL71A, VAL99A
• A-D: ALA147D, ALA291A, ALA385A, ALA416A, ALA460A, ALA461A, ALA463A, ALA70D, ARG146D, ARG198D, ARG293A, ARG337A, ARG343A, ARG344A, ARG347A, ARG384A, ARG386A, ARG390A, ARG423A, ASN105D, ASN129D, ASN152D, ASN163D, ASN187D, ASN296A, ASN321A, ASN462A, ASN466A, ASN77D, ASP121D, ASP126D, ASP139D, ASP335A, ASP373A, ASP467A, ASP50D, CYS162D, CYS336A, CYS382A, CYS458A, GLN125D, GLN49D, GLU288A, GLU312A, GLU313A, GLU72D, GLY102D, GLY150D, GLY265A, GLY320A, GLY464A, GLY465A, GLY74D, GLY98D, HIS145D, HIS174D, HIS176D, HIS317A, HIS425A, ILE116D, ILE118D, ILE143D, ILE459A, ILE95D, LEU103D, LEU119D, LEU120D, LEU127D, LEU140D, LEU151D, LEU164D, LEU175D, LEU295A, LEU338A, LEU339A, LEU375A, LEU418A, LEU420A, LEU426A, LEU457A, LEU94D, LEU97D, LYS424A, LYS93D, MET123D, MET469A, PHE100D, PHE148D, PHE316A, PHE380A, PHE80D, PRO289A, PRO422A, PRO470A, PRO73D, PRO96D, SER104D, SER144D, SER149D, SER166D, SER173D, SER266A, SER314A, SER318A, SER421A, SER468A, THR101D, THR165D, THR381A, THR455A, TRP340A, TYR122D, TYR128D, TYR142D, TYR290A, VAL117D, VAL141D, VAL315A, VAL319A, VAL341A, VAL374A, VAL427A, VAL71D, VAL99D
• B-C: ALA291C, ALA385C, ALA416C, ALA460C, ALA461C, ALA463C, ALA70B, ALA75B, ARG146B, ARG198B, ARG293C, ARG337C, ARG343C, ARG344C, ARG347C, ARG384C, ARG386C, ARG390C, ARG423C, ASN105B, ASN129B, ASN138B, ASN152B, ASN163B, ASN187B, ASN296C, ASN321C, ASN462C, ASN466C, ASN77B, ASN78B, ASP121B, ASP126B, ASP139B, ASP335C, ASP373C, ASP467C, ASP50B, CYS162B, CYS336C, CYS382C, CYS458C, GLN125B, GLN49B, GLU288C, GLU312C, GLU313C, GLU72B, GLY102B, GLY150B, GLY265C, GLY294C, GLY320C, GLY464C, GLY465C, GLY74B, GLY98B, HIS145B, HIS174B, HIS176B, HIS317C, HIS425C, ILE116B, ILE118B, ILE143B, ILE459C, ILE95B, LEU103B, LEU119B, LEU120B, LEU127B, LEU140B, LEU151B, LEU164B, LEU175B, LEU322C, LEU338C, LEU339C, LEU348C, LEU375C, LEU376C, LEU418C, LEU420C, LEU426C, LEU457C, LEU94B, LEU97B, LYS424C, LYS93B, MET123B, MET469C, PHE100B, PHE148B, PHE316C, PHE342C, PHE380C, PHE76B, PHE80B, PRO289C, PRO377C, PRO413C, PRO422C, PRO470C, PRO73B, PRO96B, SER104B, SER144B, SER149B, SER153B, SER166B, SER173B, SER266C, SER314C, SER318C, SER421C, SER468C, SER69B, THR101B, THR165B, THR381C, THR455C, TRP340C, TRP419C, TYR122B, TYR128B, TYR142B, TYR290C, VAL117B, VAL141B, VAL315C, VAL319C, VAL341C, VAL374C, VAL427C, VAL71B, VAL99B
• C-D: ALA147C, ALA171C, ALA291D, ALA385D, ALA416D, ALA460D, ALA461D, ALA463D, ALA53C, ALA70C, ARG146C, ARG198C, ARG201C, ARG293D, ARG337D, ARG343D, ARG344D, ARG345D, ARG347D, ARG384D, ARG390D, ARG423D, ASN105C, ASN129C, ASN138C, ASN152C, ASN163C, ASN187C, ASN296D, ASN321D, ASN378D, ASN462D, ASN466D, ASN77C, ASN78C, ASP121C, ASP126C, ASP139C, ASP373D, ASP467D, ASP50C, CYS162C, CYS336D, CYS382D, CYS458D, GLN125C, GLN49C, GLU288D, GLU312D, GLU313D, GLU72C, GLY102C, GLY150C, GLY177C, GLY265D, GLY294D, GLY320D, GLY464D, GLY465D, GLY74C, GLY98C, HIS145C, HIS174C, HIS176C, HIS269D, HIS317D, HIS425D, ILE118C, ILE143C, ILE387D, ILE459D, ILE95C, LEU103C, LEU119C, LEU120C, LEU127C, LEU140C, LEU151C, LEU164C, LEU175C, LEU295D, LEU322D, LEU339D, LEU375D, LEU376D, LEU418D, LEU420D, LEU426D, LEU457D, LEU79C, LEU94C, LEU97C, LYS424D, LYS430D, LYS93C, MET123C, MET469D, PHE124C, PHE148C, PHE316D, PHE342D, PHE80C, PRO289D, PRO377D, PRO422D, PRO73C, PRO96C, SER104C, SER144C, SER149C, SER153C, SER166C, SER173C, SER266D, SER314D, SER318D, SER421D, SER468D, SER54C, SER69C, THR101C, THR165C, THR381D, TRP340D, TRP346D, TRP419D, TYR122C, TYR128C, TYR142C, TYR200C, TYR290D, TYR297D, TYR379D, VAL117C, VAL141C, VAL315D, VAL319D, VAL374D, VAL427D, VAL71C, VAL99C