2I2X

crystal structure of methanol:cobalamin methyltransferase complex mtabc from methanosarcina barkeri

• Total interactions analyzed: 120
• Total true interactions: 35
• Strongest Interaction:
  • Chains: E-F
  • Int. Res.: 169
  • Norm. En. per Res.: -4.2641
• Hub Node: E(6)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-105.6949	-126.0612	-476.563	-708.3191	175	20	12	18802	14	62	60
A-C	-124.976	-9.3039	-646.688	-780.9679	199	27	16	24201	6	37	43
A-D	-30.0143	-4.358	-152.841	-187.2133	85	5	5	6215	4	27	24
A-I	-29.5133	-28.1701	-102.798	-160.4814	90	4	0	4562	3	22	33
A-L	0.0	0.0	-0.2511	-0.2511	12	0	0	115	0	2	2
B-C	-23.0047	-9.5637	-156.631	-189.1994	86	7	5	6266	1	27	24
B-O	0.0	0.0	-0.8325	-0.8325	15	0	0	253	0	1	2
C-D	-117.1566	-139.8017	-470.095	-727.0533	171	22	11	18749	13	64	58
C-N	0.0	0.0	-1.9293	-1.9293	17	0	0	387	0	4	4
C-O	-22.7434	-29.2415	-98.2388	-150.2237	85	1	0	4298	4	22	30
D-I	0.0	0.0	-2.3633	-2.3633	18	0	0	437	0	4	3
E-F	-123.1514	-125.87	-471.618	-720.6394	169	23	13	18671	11	61	59
E-G	-140.1098	9.4047	-649.065	-779.7701	199	22	17	23921	6	35	42
E-H	-25.733	2.9441	-142.004	-164.7928	81	7	5	6068	2	24	26
E-I	0.0	0.0	-0.0025	-0.0025	2	0	0	2	0	2	1
E-J	0.0	13.5057	-3.2552	10.2506	14	0	0	400	0	6	6
E-K	-23.0466	-33.8721	-9.5176	-66.4363	28	4	0	915	2	18	12
F-G	-17.0632	-0.0734	-149.828	-166.9646	87	5	5	6249	1	24	25
F-M	0.0	-0.8307	-4.0523	-4.8829	20	0	0	532	0	5	4
G-H	-128.0338	-132.5943	-459.148	-719.7761	176	26	12	18786	12	61	61
G-K	0.0	0.0	-0.2817	-0.2817	8	0	0	57	0	3	1
G-M	-47.491	-60.8497	-80.1273	-188.468	87	4	0	4042	5	22	25
G-P	0.0	0.0	-1.6256	-1.6256	16	0	0	366	0	2	3
H-J	0.0	0.0	-0.0003	-0.0003	2	0	0	1	0	0	0
H-K	0.0	31.7165	-15.0063	16.7102	30	1	0	852	0	7	13
I-J	-98.8669	-140.9663	-496.543	-736.3762	175	22	10	19050	14	61	56
I-K	-130.5831	-8.5171	-661.992	-801.0922	201	21	17	24140	6	37	41
I-L	-21.4374	2.4213	-157.52	-176.5361	79	3	5	6222	1	25	25
J-K	-30.0962	-48.8755	-159.768	-238.7397	84	3	5	6297	4	25	24
K-L	-103.0828	-125.8146	-469.41	-698.3074	173	28	12	18956	14	61	61
M-N	-98.2953	-135.605	-471.537	-705.4373	174	20	12	18686	14	64	58
M-O	-108.9238	-6.265	-658.507	-773.6958	200	18	19	24205	6	34	43
M-P	-36.7803	0.7617	-149.4	-185.4186	83	7	5	6238	1	26	23
N-O	-33.4643	-0.1792	-160.679	-194.3225	85	6	5	6492	2	25	24
O-P	-93.4608	-129.7602	-475.647	-698.8681	173	23	13	18711	14	61	58

Interface residues

• A-B: ALA102B, ALA104B, ALA145B, ALA14A, ALA163B, ALA175A, ALA19B, ALA221A, ALA226A, ALA231B, ALA232B, ALA239A, ALA23B, ALA367A, ALA371A, ALA375A, ALA421A, ALA46A, ALA7B, ARG133A, ARG159B, ARG15B, ARG178A, ARG353A, ARG361A, ARG363A, ARG416A, ARG48A, ARG86B, ASN132A, ASN141B, ASN179A, ASN17B, ASN235A, ASN237A, ASN374A, ASN97B, ASP103B, ASP134B, ASP137B, ASP15A, ASP160B, ASP173A, ASP180A, ASP354A, ASP360A, ASP364A, ASP373A, ASP3B, ASP424A, ASP89B, GLN305A, GLN366A, GLN89A, GLN90A, GLU131A, GLU132B, GLU134A, GLU165B, GLU170A, GLU21B, GLU230B, GLU27B, GLU316A, GLU413A, GLU418A, GLU450A, GLU50A, GLU52B, GLU6B, GLU90B, GLY133B, GLY139B, GLY158B, GLY212B, GLY230A, GLY232A, GLY410A, GLY52A, GLY91B, HIS129B, HIS136B, HIS240A, HIS318A, HIS87A, ILE138B, ILE142B, ILE229A, ILE242A, ILE85B, ILE93B, LEU106B, LEU136A, LEU13B, LEU146B, LEU157B, LEU177A, LEU183B, LEU20B, LEU233A, LEU234A, LEU238A, LEU24B, LEU2B, LEU352A, LEU355A, LEU358A, LEU412A, LEU414A, LEU87B, LEU95B, LEU9B, LYS10B, LYS140B, LYS169A, LYS22B, LYS236A, LYS350A, LYS411A, LYS420A, MET100B, MET166A, MET184B, MET188B, MET1B, MET356A, MET357A, MET99B, PHE135A, PHE172A, PHE218B, PHE228A, PHE417A, PHE48B, PHE4B, PHE94B, PRO162B, PRO26B, PRO365A, PRO47A, PRO49A, PRO96B, SER101B, SER359A, SER415A, SER8B, THR14B, THR185B, THR186B, THR187B, THR225A, THR241A, THR25B, THR419A, THR5B, TYR16B, TYR174A, TYR189B, TYR362A, TYR368A, TYR372A, TYR88B, VAL12B, VAL130B, VAL135B, VAL161B, VAL166B, VAL176A, VAL18B, VAL298A, VAL351A, VAL453A, VAL88A, VAL92B, VAL98B
• A-C: ALA294A, ALA294C, ALA334A, ALA334C, ALA338A, ALA338C, ALA343A, ALA343C, ALA367A, ALA367C, ALA46A, ALA46C, ARG353A, ARG353C, ARG361A, ARG361C, ARG363A, ARG363C, ARG48A, ARG48C, ARG72A, ARG72C, ASN235A, ASN235C, ASN301A, ASN301C, ASN312A, ASN312C, ASN341A, ASN341C, ASN348A, ASN348C, ASN44A, ASN44C, ASP297A, ASP297C, ASP336A, ASP336C, ASP349A, ASP349C, ASP354A, ASP354C, ASP360A, ASP360C, ASP364A, ASP364C, CYS293A, CYS293C, CYS328A, CYS328C, CYS337A, CYS337C, GLN327A, GLN327C, GLN75A, GLN75C, GLU115A, GLU115C, GLU313A, GLU313C, GLU316A, GLU316C, GLU320A, GLU320C, GLU331A, GLU331C, GLU345A, GLU345C, GLU71A, GLU71C, GLU86A, GLU86C, GLY230A, GLY230C, GLY231A, GLY231C, GLY232A, GLY232C, GLY288A, GLY288C, GLY300A, GLY300C, GLY319A, GLY319C, GLY322A, GLY322C, GLY323A, GLY323C, GLY77A, GLY77C, HIS240A, HIS240C, HIS295A, HIS295C, HIS318A, HIS318C, LEU233A, LEU233C, LEU234A, LEU234C, LEU302A, LEU302C, LEU333A, LEU333C, LEU339A, LEU339C, LEU344A, LEU344C, LEU352A, LEU352C, LEU355A, LEU355C, LEU358A, LEU358C, LYS236A, LYS236C, LYS289A, LYS289C, LYS347A, LYS347C, LYS350C, MET299A, MET299C, MET304A, MET304C, MET340A, MET340C, MET356A, MET356C, MET357A, MET357C, MET70A, MET70C, MET73A, MET73C, PHE19A, PHE19C, PHE228A, PHE228C, PHE321A, PHE321C, PHE78A, PHE78C, PRO47A, PRO47C, PRO49A, PRO49C, PRO79A, PRO79C, SER291A, SER291C, SER296A, SER296C, SER314A, SER314C, SER330A, SER330C, SER359A, SER359C, THR290A, THR290C, THR292A, THR292C, THR324A, THR324C, THR325A, THR325C, THR332A, THR332C, THR342A, THR342C, THR346A, THR346C, TRP310A, TRP310C, TRP329A, TRP329C, TYR112A, TYR112C, TYR116A, TYR116C, TYR317A, TYR317C, TYR335A, TYR335C, TYR362A, TYR45A, TYR45C, VAL298A, VAL298C, VAL303A, VAL315A, VAL315C, VAL351A, VAL351C, VAL74A, VAL74C, VAL76A, VAL76C
• A-D: ALA19D, ALA213D, ALA334A, ALA338A, ALA343A, ALA36A, ALA7D, ALA80A, ARG15D, ARG48A, ARG64A, ARG72A, ASN17D, ASN215D, ASN341A, ASN348A, ASP114A, ASP217D, ASP3D, ASP68A, CYS337A, GLN216D, GLN75A, GLU115A, GLU229D, GLU320A, GLU345A, GLU50A, GLU56A, GLU61A, GLU63A, GLU71A, GLY117A, GLY20A, GLY212D, GLY319A, GLY323A, GLY37A, GLY77A, HIS113A, HIS256D, HIS258D, ILE108A, ILE118A, ILE81A, LEU13D, LEU183D, LEU20D, LEU2D, LEU339A, LEU344A, LEU9D, LYS10D, LYS119A, LYS11D, LYS257D, LYS347A, LYS60A, MET184D, MET340A, MET73A, PHE321A, PHE4D, PHE78A, PRO79A, SER8D, THR14D, THR185D, THR186D, THR342A, THR346A, THR39A, THR5D, THR67A, TYR112A, TYR116A, TYR16D, TYR317A, TYR335A, TYR38A, VAL12D, VAL21A, VAL351A, VAL74A, VAL76A
• A-I: ALA10A, ALA10I, ALA12A, ALA12I, ALA207A, ALA207I, ALA262A, ALA262I, ALA36A, ALA36I, ARG5I, ASN13A, ASN13I, ASP15A, ASP15I, ASP31A, ASP31I, GLU16A, GLU16I, GLU259I, GLU33A, GLU33I, GLU345A, GLU345I, GLY20A, GLY20I, GLY211A, GLY211I, GLY261I, GLY281A, GLY281I, GLY29A, GLY35A, GLY35I, GLY37A, GLY37I, HIS113A, HIS113I, ILE34A, ILE34I, LEU30A, LEU30I, LEU32A, LEU344A, LYS119A, LYS119I, LYS208A, LYS208I, LYS209A, LYS209I, LYS23A, LYS23I, LYS27A, LYS27I, LYS347A, LYS347I, LYS350A, LYS350I, LYS4A, LYS4I, MET282A, MET282I, PRO25A, PRO25I, PRO283I, SER22A, SER22I, SER8A, SER8I, THR210A, THR210I, THR212A, THR212I, THR280A, THR280I, THR7I, TYR24A, TYR24I, TYR258A, TYR258I, TYR38A, TYR38I, TYR6A, TYR6I, VAL21A, VAL21I, VAL263A, VAL263I, VAL26A, VAL26I
• A-L: ALA10A, ALA12A, ALA7L, LYS10L, LYS11L, LYS23A, MET9A, SER8A, SER8L, THR5L, THR7A, TYR11A
• B-C: ALA19B, ALA213B, ALA334C, ALA338C, ALA343C, ALA36C, ALA7B, ALA80C, ARG15B, ARG48C, ARG64C, ARG72C, ASN17B, ASN215B, ASN341C, ASN348C, ASP114C, ASP217B, ASP3B, CYS120C, CYS337C, GLN216B, GLN75C, GLU115C, GLU320C, GLU33C, GLU345C, GLU50C, GLU56C, GLU61C, GLU63C, GLY117C, GLY20C, GLY212B, GLY319C, GLY323C, GLY37C, GLY77C, HIS113C, HIS256B, HIS258B, HIS318C, ILE118C, ILE81C, LEU13B, LEU183B, LEU20B, LEU2B, LEU339C, LEU344C, LEU9B, LYS10B, LYS119C, LYS11B, LYS257B, LYS347C, LYS57C, LYS60C, MET184B, MET340C, MET70C, MET73C, PHE321C, PHE4B, PHE78C, PRO79C, SER8B, THR14B, THR185B, THR186B, THR324C, THR342C, THR346C, THR5B, THR67C, TYR112C, TYR116C, TYR16B, TYR227B, TYR317C, TYR335C, TYR38C, VAL12B, VAL351C, VAL74C, VAL76C
• B-O: ALA10O, ALA12O, ALA7B, ASN13O, GLN380O, LYS10B, LYS11B, LYS23O, MET9O, SER8B, SER8O, THR5B, THR7O, TYR11O, TYR376O
• C-D: ALA102D, ALA104D, ALA145D, ALA14C, ALA163D, ALA175C, ALA19D, ALA221C, ALA226C, ALA231D, ALA232D, ALA239C, ALA23D, ALA367C, ALA371C, ALA375C, ALA421C, ALA46C, ALA7D, ARG133C, ARG148D, ARG159D, ARG15D, ARG178C, ARG353C, ARG361C, ARG363C, ARG416C, ARG48C, ARG86D, ASN132C, ASN141D, ASN179C, ASN17D, ASN235C, ASN237C, ASN374C, ASN97D, ASP103D, ASP134D, ASP137D, ASP15C, ASP160D, ASP173C, ASP180C, ASP354C, ASP360C, ASP364C, ASP373C, ASP3D, ASP424C, ASP89D, GLN222C, GLN305C, GLN366C, GLN89C, GLN90C, GLU131C, GLU132D, GLU134C, GLU165D, GLU170C, GLU21D, GLU230D, GLU27D, GLU316C, GLU413C, GLU418C, GLU450C, GLU50C, GLU6D, GLU90D, GLY133D, GLY139D, GLY158D, GLY230C, GLY232C, GLY410C, GLY52C, GLY91D, HIS129D, HIS136D, HIS240C, HIS87C, ILE138D, ILE142D, ILE229C, ILE242C, ILE85D, ILE93D, LEU106D, LEU136C, LEU13D, LEU146D, LEU157D, LEU177C, LEU20D, LEU233C, LEU234C, LEU238C, LEU24D, LEU2D, LEU352C, LEU355C, LEU358C, LEU412C, LEU414C, LEU87D, LEU95D, LEU9D, LYS10D, LYS169C, LYS22D, LYS236C, LYS350C, LYS411C, LYS420C, MET100D, MET166C, MET184D, MET188D, MET1D, MET356C, MET357C, MET99D, PHE135C, PHE172C, PHE228C, PHE417C, PHE48D, PHE4D, PHE94D, PRO162D, PRO26D, PRO365C, PRO47C, PRO49C, PRO96D, SER101D, SER359C, SER415C, SER8D, THR14D, THR185D, THR186D, THR187D, THR225C, THR241C, THR25D, THR419C, THR5D, TYR16D, TYR174C, TYR189D, TYR362C, TYR368C, TYR372C, TYR88D, VAL12D, VAL130D, VAL135D, VAL161D, VAL166D, VAL176C, VAL18D, VAL298C, VAL351C, VAL453C, VAL88C, VAL92D, VAL98D
• C-N: ALA10C, ALA12C, ALA7N, ASN13C, GLN380C, LYS10N, LYS11N, LYS23C, LYS384C, MET9C, SER8C, SER8N, THR5N, THR7C, TYR11C, TYR376C, VAL383C
• C-O: ALA10C, ALA10O, ALA12C, ALA12O, ALA207C, ALA207O, ALA262C, ALA262O, ALA36C, ALA36O, ASN13C, ASN13O, ASP15C, ASP15O, ASP31C, ASP31O, GLU16C, GLU16O, GLU33C, GLU33O, GLU345C, GLU345O, GLY20C, GLY20O, GLY211C, GLY211O, GLY281C, GLY281O, GLY35C, GLY35O, GLY37C, GLY37O, HIS113C, HIS113O, ILE34C, ILE34O, LEU30O, LEU344C, LEU344O, LYS119C, LYS119O, LYS208C, LYS208O, LYS209C, LYS209O, LYS23C, LYS23O, LYS27C, LYS27O, LYS347C, LYS347O, LYS4C, LYS4O, MET282C, MET282O, PRO25C, PRO25O, PRO283C, SER22C, SER22O, SER8C, SER8O, THR210C, THR210O, THR212C, THR212O, THR280C, THR280O, THR7C, TYR11C, TYR11O, TYR24C, TYR24O, TYR258C, TYR258O, TYR38C, TYR38O, TYR6C, TYR6O, VAL21C, VAL21O, VAL263C, VAL263O, VAL26C, VAL26O
• D-I: ALA10I, ALA12I, ALA7D, ASN13I, GLN380I, GLU6D, LYS10D, LYS11D, LYS23I, LYS384I, MET9I, SER8D, SER8I, THR5D, THR7I, TYR11I, TYR376I, VAL383I
• E-F: ALA102F, ALA145F, ALA14E, ALA175E, ALA19F, ALA221E, ALA226E, ALA231F, ALA232F, ALA239E, ALA23F, ALA367E, ALA371E, ALA375E, ALA421E, ALA46E, ALA7F, ARG133E, ARG148F, ARG159F, ARG15F, ARG178E, ARG353E, ARG361E, ARG363E, ARG416E, ARG48E, ARG86F, ASN132E, ASN141F, ASN179E, ASN17F, ASN235E, ASN237E, ASN374E, ASN97F, ASP103F, ASP134F, ASP137F, ASP15E, ASP160F, ASP173E, ASP180E, ASP354E, ASP360E, ASP364E, ASP373E, ASP3F, ASP424E, ASP89F, GLN222E, GLN305E, GLN366E, GLN89E, GLN90E, GLU131E, GLU132F, GLU134E, GLU165F, GLU170E, GLU21F, GLU230F, GLU27F, GLU316E, GLU413E, GLU418E, GLU50E, GLU6F, GLU90F, GLY133F, GLY139F, GLY158F, GLY230E, GLY232E, GLY410E, GLY52E, GLY91F, HIS129F, HIS136F, HIS240E, HIS318E, HIS87E, ILE138F, ILE142F, ILE229E, ILE242E, ILE85F, ILE93F, LEU106F, LEU136E, LEU13F, LEU146F, LEU157F, LEU177E, LEU20F, LEU233E, LEU234E, LEU238E, LEU24F, LEU2F, LEU352E, LEU355E, LEU358E, LEU412E, LEU414E, LEU87F, LEU95F, LEU9F, LYS10F, LYS169E, LYS22F, LYS236E, LYS350E, LYS411E, LYS420E, MET100F, MET166E, MET184F, MET188F, MET1F, MET356E, MET357E, MET99F, PHE135E, PHE172E, PHE228E, PHE417E, PHE48F, PHE4F, PHE94F, PRO162F, PRO26F, PRO365E, PRO47E, PRO49E, PRO96F, SER101F, SER359E, SER415E, SER8F, THR144F, THR14F, THR185F, THR186F, THR187F, THR225E, THR241E, THR25F, THR419E, THR5F, TYR16F, TYR174E, TYR189F, TYR362E, TYR368E, TYR372E, TYR88F, VAL12F, VAL130F, VAL135F, VAL161F, VAL176E, VAL18F, VAL298E, VAL351E, VAL453E, VAL88E, VAL92F, VAL98F
• E-G: ALA294E, ALA294G, ALA334E, ALA334G, ALA338E, ALA338G, ALA343E, ALA343G, ALA367E, ALA367G, ALA46E, ALA46G, ARG353E, ARG353G, ARG361E, ARG361G, ARG363E, ARG363G, ARG48E, ARG48G, ARG72E, ARG72G, ASN235E, ASN235G, ASN301E, ASN301G, ASN312E, ASN312G, ASN341E, ASN341G, ASN348E, ASN348G, ASN44E, ASN44G, ASP297E, ASP297G, ASP336E, ASP336G, ASP349E, ASP349G, ASP354E, ASP354G, ASP360E, ASP360G, ASP364E, ASP364G, CYS293E, CYS293G, CYS328E, CYS328G, CYS337E, CYS337G, GLN327E, GLN327G, GLN75E, GLN75G, GLU115E, GLU115G, GLU313E, GLU313G, GLU316E, GLU316G, GLU320E, GLU320G, GLU331E, GLU331G, GLU345E, GLU345G, GLU71E, GLU71G, GLU86E, GLU86G, GLY230E, GLY230G, GLY231E, GLY231G, GLY232E, GLY232G, GLY288E, GLY288G, GLY300E, GLY300G, GLY319E, GLY319G, GLY322E, GLY322G, GLY323E, GLY323G, GLY77E, GLY77G, HIS240E, HIS240G, HIS295E, HIS295G, HIS318E, HIS318G, LEU233E, LEU233G, LEU234E, LEU234G, LEU302E, LEU302G, LEU333E, LEU333G, LEU339E, LEU339G, LEU344E, LEU344G, LEU352E, LEU352G, LEU355E, LEU355G, LEU358E, LEU358G, LYS236E, LYS236G, LYS289E, LYS289G, LYS347E, LYS347G, MET299E, MET299G, MET304E, MET304G, MET340E, MET340G, MET356E, MET356G, MET357E, MET357G, MET70E, MET70G, MET73E, MET73G, PHE19E, PHE19G, PHE228E, PHE228G, PHE321E, PHE321G, PHE78E, PHE78G, PRO47E, PRO47G, PRO49E, PRO49G, PRO79E, PRO79G, SER291E, SER291G, SER296E, SER296G, SER314E, SER314G, SER330E, SER330G, SER359E, SER359G, THR290E, THR290G, THR292E, THR292G, THR324E, THR324G, THR325E, THR325G, THR332E, THR332G, THR342E, THR342G, THR346E, THR346G, TRP310E, TRP310G, TRP329E, TRP329G, TYR112E, TYR112G, TYR116E, TYR116G, TYR317E, TYR317G, TYR335E, TYR335G, TYR362E, TYR45E, TYR45G, VAL298E, VAL298G, VAL303E, VAL303G, VAL315E, VAL315G, VAL351E, VAL351G, VAL74E, VAL74G, VAL76E, VAL76G
• E-H: ALA19H, ALA213H, ALA334E, ALA338E, ALA343E, ALA36E, ALA7H, ALA80E, ARG15H, ARG48E, ARG64E, ARG72E, ASN17H, ASN215H, ASN341E, ASN348E, ASP114E, ASP217H, ASP3H, CYS337E, GLN216H, GLN75E, GLU115E, GLU320E, GLU345E, GLU50E, GLU56E, GLU61E, GLU63E, GLY117E, GLY212H, GLY319E, GLY323E, GLY37E, GLY77E, HIS113E, HIS256H, HIS258H, HIS318E, ILE118E, LEU13H, LEU183H, LEU20H, LEU2H, LEU339E, LEU344E, LEU9H, LYS10H, LYS119E, LYS11H, LYS257H, LYS347E, LYS60E, MET184H, MET340E, MET73E, PHE218H, PHE321E, PHE4H, PHE78E, PRO79E, SER220H, SER8H, THR14H, THR185H, THR186H, THR342E, THR346E, THR5H, THR67E, TYR112E, TYR116E, TYR16H, TYR227H, TYR317E, TYR335E, TYR38E, VAL12H, VAL351E, VAL74E, VAL76E
• E-I: GLU413I, LYS23E
• E-J: ALA12E, ALA23J, ALA7J, GLU16E, GLU6J, LYS10J, LYS23E, LYS347E, LYS4E, PRO25E, SER22E, THR5J, TYR24E, VAL21E
• E-K: ALA28E, ASP114E, ASP114K, ASP31E, ASP31K, GLU33E, GLU33K, GLU345E, GLY117E, GLY29E, HIS113E, HIS113K, LEU30E, LEU30K, LEU32E, LEU32K, LYS119E, LYS119K, LYS208E, LYS208K, LYS27E, LYS27K, LYS347E, LYS347K, PRO25K, TYR24K, TYR38K, VAL26K
• F-G: ALA19F, ALA213F, ALA334G, ALA338G, ALA343G, ALA36G, ALA7F, ALA80G, ARG15F, ARG48G, ARG64G, ARG72G, ASN17F, ASN215F, ASN341G, ASN348G, ASP114G, ASP217F, ASP3F, CYS337G, GLN216F, GLN75G, GLU115G, GLU320G, GLU33G, GLU345G, GLU50G, GLU56G, GLU61G, GLU63G, GLY117G, GLY20G, GLY212F, GLY319G, GLY323G, GLY37G, GLY77G, HIS113G, HIS256F, HIS258F, HIS318G, ILE118G, ILE81G, LEU13F, LEU183F, LEU20F, LEU2F, LEU339G, LEU344G, LEU9F, LYS10F, LYS119G, LYS11F, LYS257F, LYS347G, LYS57G, LYS60G, MET184F, MET188F, MET340G, MET70G, MET73G, PHE321G, PHE4F, PHE78G, PRO79G, SER8F, THR14F, THR185F, THR186F, THR342G, THR346G, THR39G, THR5F, THR67G, TYR112G, TYR116G, TYR16F, TYR227F, TYR317G, TYR335G, TYR38G, VAL12F, VAL21G, VAL351G, VAL74G, VAL76G
• F-M: ALA10M, ALA12M, ALA7F, ASN13M, GLN380M, GLU16M, GLU6F, LYS10F, LYS11F, LYS23M, LYS384M, MET9M, SER8F, SER8M, THR5F, THR7M, TYR11M, TYR376M, TYR6M, VAL383M
• G-H: ALA102H, ALA131H, ALA145H, ALA14G, ALA175G, ALA19H, ALA221G, ALA226G, ALA231H, ALA232H, ALA239G, ALA23H, ALA367G, ALA371G, ALA375G, ALA421G, ALA46G, ALA7H, ARG133G, ARG148H, ARG159H, ARG15H, ARG178G, ARG353G, ARG361G, ARG363G, ARG416G, ARG48G, ARG86H, ASN132G, ASN141H, ASN179G, ASN17H, ASN235G, ASN237G, ASN374G, ASN97H, ASP103H, ASP134H, ASP137H, ASP156H, ASP15G, ASP160H, ASP173G, ASP180G, ASP354G, ASP360G, ASP364G, ASP373G, ASP3H, ASP424G, ASP89H, GLN222G, GLN305G, GLN366G, GLN89G, GLN90G, GLU131G, GLU132H, GLU134G, GLU165H, GLU170G, GLU21H, GLU230H, GLU27H, GLU28H, GLU316G, GLU413G, GLU418G, GLU450G, GLU50G, GLU52H, GLU6H, GLU90H, GLY133H, GLY139H, GLY158H, GLY230G, GLY232G, GLY410G, GLY52G, GLY91H, HIS129H, HIS136H, HIS240G, HIS318G, HIS87G, ILE138H, ILE142H, ILE229G, ILE242G, ILE85H, ILE93H, LEU106H, LEU136G, LEU13H, LEU146H, LEU157H, LEU177G, LEU183H, LEU20H, LEU233G, LEU234G, LEU238G, LEU24H, LEU2H, LEU352G, LEU355G, LEU358G, LEU412G, LEU414G, LEU87H, LEU95H, LEU9H, LYS10H, LYS140H, LYS169G, LYS22H, LYS236G, LYS350G, LYS411G, LYS420G, MET100H, MET166G, MET184H, MET188H, MET1H, MET356G, MET357G, MET99H, PHE135G, PHE172G, PHE228G, PHE417G, PHE48H, PHE4H, PHE94H, PRO162H, PRO26H, PRO365G, PRO47G, PRO49G, PRO96H, SER101H, SER359G, SER415G, SER8H, THR14H, THR185H, THR186H, THR187H, THR225G, THR241G, THR25H, THR419G, THR5H, TYR16H, TYR174G, TYR189H, TYR362G, TYR368G, TYR372G, TYR88H, VAL12H, VAL130H, VAL135H, VAL161H, VAL166H, VAL176G, VAL18H, VAL298G, VAL351G, VAL453G, VAL88G, VAL92H, VAL98H
• G-K: ALA12K, ARG416G, GLU16K, GLU413G, LYS23K, LYS411G, SER8K, THR7K
• G-M: ALA10G, ALA10M, ALA12G, ALA12M, ALA262G, ALA262M, ALA36G, ALA36M, ASN13G, ASN13M, ASP15G, ASP15M, ASP31G, ASP31M, GLU16G, GLU16M, GLU33G, GLU33M, GLU345G, GLU345M, GLY117G, GLY20G, GLY20M, GLY211G, GLY211M, GLY261G, GLY281G, GLY281M, GLY35G, GLY35M, GLY37G, GLY37M, HIS113G, HIS113M, ILE34G, ILE34M, LEU30G, LEU344G, LEU344M, LYS119G, LYS119M, LYS208G, LYS208M, LYS209G, LYS209M, LYS23G, LYS23M, LYS27G, LYS27M, LYS347G, LYS347M, LYS350G, LYS350M, LYS4G, LYS4M, MET282G, MET282M, PRO25G, PRO25M, SER22G, SER22M, SER8G, SER8M, THR210G, THR210M, THR212G, THR212M, THR280G, THR280M, THR346M, THR7M, TYR11G, TYR11M, TYR24G, TYR24M, TYR258G, TYR258M, TYR38G, TYR38M, TYR6G, TYR6M, VAL21G, VAL21M, VAL263G, VAL263M, VAL26G, VAL26M
• G-P: ALA10G, ALA12G, ALA7P, ASN13G, GLN380G, LYS10P, LYS11P, LYS23G, MET9G, SER8G, SER8P, THR5P, THR7G, TYR11G, TYR376G, VAL383G
• H-J: LYS11H, LYS11J
• H-K: ALA10K, ALA12K, ALA19H, ALA23H, ALA7H, ARG5K, ASN13K, ASP15K, ASP387K, GLU16K, GLU6H, GLY281K, LEU24H, LYS10H, LYS22H, LYS23K, LYS347K, LYS350K, LYS4K, PRO25K, SER22K, SER8H, SER8K, THR5H, THR7K, TYR11K, TYR24K, TYR6K, VAL18H, VAL21K
• I-J: ALA102J, ALA104J, ALA145J, ALA14I, ALA163J, ALA175I, ALA19J, ALA221I, ALA226I, ALA231J, ALA232J, ALA239I, ALA23J, ALA367I, ALA371I, ALA375I, ALA421I, ALA46I, ALA51I, ALA7J, ARG133I, ARG148J, ARG159J, ARG15J, ARG178I, ARG353I, ARG361I, ARG363I, ARG416I, ARG48I, ARG86J, ASN132I, ASN141J, ASN179I, ASN17J, ASN235I, ASN237I, ASN374I, ASN97J, ASP103J, ASP134J, ASP137J, ASP15I, ASP160J, ASP173I, ASP180I, ASP354I, ASP360I, ASP364I, ASP373I, ASP3J, ASP424I, ASP89J, GLN222I, GLN305I, GLN366I, GLN89I, GLN90I, GLU131I, GLU132J, GLU134I, GLU165J, GLU170I, GLU21J, GLU230J, GLU27J, GLU316I, GLU413I, GLU418I, GLU450I, GLU50I, GLU6J, GLU90J, GLY133J, GLY139J, GLY158J, GLY230I, GLY232I, GLY410I, GLY52I, GLY91J, HIS129J, HIS136J, HIS240I, HIS318I, ILE138J, ILE142J, ILE229I, ILE242I, ILE85J, ILE93J, LEU106J, LEU136I, LEU13J, LEU146J, LEU157J, LEU177I, LEU20J, LEU233I, LEU234I, LEU238I, LEU24J, LEU2J, LEU352I, LEU355I, LEU358I, LEU412I, LEU414I, LEU87J, LEU95J, LEU9J, LYS10J, LYS140J, LYS169I, LYS22J, LYS236I, LYS350I, LYS411I, LYS420I, MET100J, MET166I, MET184J, MET188J, MET1J, MET356I, MET357I, MET99J, PHE135I, PHE172I, PHE228I, PHE417I, PHE48J, PHE4J, PHE94J, PRO162J, PRO26J, PRO365I, PRO47I, PRO49I, PRO96J, SER101J, SER359I, SER415I, SER8J, THR144J, THR14J, THR185J, THR186J, THR187J, THR225I, THR241I, THR25J, THR419I, THR5J, TYR16J, TYR174I, TYR189J, TYR362I, TYR368I, TYR372I, TYR88J, VAL12J, VAL130J, VAL135J, VAL143J, VAL161J, VAL166J, VAL176I, VAL18J, VAL298I, VAL351I, VAL453I, VAL88I, VAL92J, VAL98J
• I-K: ALA294I, ALA294K, ALA334I, ALA334K, ALA338I, ALA338K, ALA343I, ALA343K, ALA367I, ALA367K, ALA46I, ALA46K, ARG353I, ARG353K, ARG361I, ARG361K, ARG363I, ARG363K, ARG48I, ARG48K, ARG72I, ARG72K, ASN235I, ASN235K, ASN301I, ASN301K, ASN312I, ASN312K, ASN341I, ASN341K, ASN348I, ASN348K, ASN44I, ASN44K, ASP297I, ASP297K, ASP336I, ASP336K, ASP349I, ASP349K, ASP354I, ASP354K, ASP360I, ASP360K, ASP364I, ASP364K, CYS293I, CYS293K, CYS328I, CYS328K, CYS337I, CYS337K, GLN327I, GLN327K, GLN75I, GLN75K, GLU115I, GLU115K, GLU313I, GLU313K, GLU316I, GLU316K, GLU320I, GLU320K, GLU331I, GLU331K, GLU345I, GLU345K, GLU71I, GLU71K, GLU86I, GLU86K, GLY230I, GLY230K, GLY231I, GLY231K, GLY232I, GLY232K, GLY288I, GLY288K, GLY300I, GLY300K, GLY319I, GLY319K, GLY322I, GLY322K, GLY323I, GLY323K, GLY77I, GLY77K, HIS240I, HIS240K, HIS295I, HIS295K, HIS318I, HIS318K, LEU233I, LEU233K, LEU234I, LEU234K, LEU302I, LEU302K, LEU333I, LEU333K, LEU339I, LEU339K, LEU344I, LEU344K, LEU352I, LEU352K, LEU355I, LEU355K, LEU358I, LEU358K, LYS236I, LYS236K, LYS289I, LYS289K, LYS347I, LYS347K, MET299I, MET299K, MET304I, MET304K, MET340I, MET340K, MET356I, MET356K, MET357I, MET357K, MET70I, MET70K, MET73I, MET73K, PHE19I, PHE19K, PHE228I, PHE228K, PHE321I, PHE321K, PHE78I, PHE78K, PRO47I, PRO47K, PRO49I, PRO49K, PRO79I, PRO79K, SER291I, SER291K, SER296I, SER296K, SER314I, SER314K, SER330I, SER330K, SER359I, SER359K, THR290I, THR290K, THR292I, THR292K, THR324I, THR324K, THR325I, THR325K, THR332I, THR332K, THR342I, THR342K, THR346I, THR346K, TRP310I, TRP310K, TRP329I, TRP329K, TYR112I, TYR112K, TYR116I, TYR116K, TYR271I, TYR271K, TYR317I, TYR317K, TYR335I, TYR335K, TYR362I, TYR45I, TYR45K, VAL298I, VAL298K, VAL303I, VAL303K, VAL315I, VAL315K, VAL351I, VAL351K, VAL74I, VAL74K, VAL76I, VAL76K
• I-L: ALA19L, ALA213L, ALA334I, ALA338I, ALA343I, ALA36I, ALA7L, ALA80I, ARG15L, ARG48I, ARG64I, ARG72I, ASN17L, ASN215L, ASN341I, ASN348I, ASP114I, ASP217L, ASP3L, CYS337I, GLN216L, GLN75I, GLU115I, GLU320I, GLU345I, GLU50I, GLU56I, GLU61I, GLU63I, GLY117I, GLY212L, GLY319I, GLY323I, GLY37I, GLY77I, HIS113I, HIS256L, HIS258L, ILE118I, LEU13L, LEU183L, LEU20L, LEU2L, LEU339I, LEU344I, LEU9L, LYS10L, LYS119I, LYS11L, LYS257L, LYS347I, LYS57I, LYS60I, MET184L, MET340I, MET70I, MET73I, PHE321I, PHE4L, PHE78I, PRO79I, SER8L, THR14L, THR185L, THR186L, THR342I, THR346I, THR5L, THR67I, TYR112I, TYR116I, TYR16L, TYR227L, TYR335I, TYR38I, VAL12L, VAL351I, VAL74I, VAL76I
• J-K: ALA19J, ALA213J, ALA334K, ALA338K, ALA343K, ALA36K, ALA7J, ALA80K, ARG15J, ARG48K, ARG64K, ARG72K, ASN17J, ASN215J, ASN341K, ASN348K, ASP114K, ASP217J, ASP3J, ASP68K, CYS337K, GLN216J, GLN75K, GLU115K, GLU320K, GLU345K, GLU56K, GLU63K, GLY117K, GLY212J, GLY319K, GLY323K, GLY37K, GLY77K, HIS113K, HIS256J, HIS258J, HIS318K, ILE108K, ILE118K, ILE59K, LEU13J, LEU183J, LEU20J, LEU2J, LEU339K, LEU344K, LEU9J, LYS10J, LYS119K, LYS11J, LYS257J, LYS347K, LYS60K, MET184J, MET340K, MET73K, PHE218J, PHE321K, PHE4J, PHE78K, PRO79K, SER220J, SER8J, THR14J, THR185J, THR186J, THR324K, THR342K, THR346K, THR39K, THR5J, THR67K, TYR112K, TYR116K, TYR16J, TYR317K, TYR335K, TYR38K, VAL12J, VAL21K, VAL351K, VAL74K, VAL76K
• K-L: ALA102L, ALA104L, ALA145L, ALA14K, ALA175K, ALA19L, ALA221K, ALA226K, ALA231L, ALA232L, ALA239K, ALA23L, ALA367K, ALA371K, ALA375K, ALA421K, ALA46K, ALA51K, ALA7L, ARG133K, ARG148L, ARG159L, ARG15L, ARG178K, ARG353K, ARG361K, ARG363K, ARG416K, ARG48K, ARG86L, ASN132K, ASN141L, ASN179K, ASN17L, ASN235K, ASN237K, ASN374K, ASN97L, ASP103L, ASP134L, ASP137L, ASP15K, ASP160L, ASP173K, ASP180K, ASP354K, ASP360K, ASP364K, ASP373K, ASP3L, ASP424K, ASP89L, GLN222K, GLN305K, GLN366K, GLN89K, GLN90K, GLU131K, GLU132L, GLU134K, GLU165L, GLU170K, GLU21L, GLU230L, GLU27L, GLU316K, GLU413K, GLU418K, GLU450K, GLU50K, GLU6L, GLU90L, GLY133L, GLY139L, GLY158L, GLY230K, GLY232K, GLY410K, GLY52K, GLY91L, HIS129L, HIS136L, HIS240K, HIS318K, HIS87K, ILE138L, ILE142L, ILE229K, ILE242K, ILE93L, LEU106L, LEU136K, LEU13L, LEU146L, LEU157L, LEU177K, LEU20L, LEU233K, LEU234K, LEU238K, LEU24L, LEU2L, LEU352K, LEU355K, LEU358K, LEU412K, LEU414K, LEU58K, LEU87L, LEU95L, LEU9L, LYS10L, LYS140L, LYS169K, LYS22L, LYS236K, LYS350K, LYS411K, LYS420K, MET100L, MET166K, MET184L, MET188L, MET1L, MET356K, MET357K, MET99L, PHE135K, PHE172K, PHE228K, PHE417K, PHE48L, PHE4L, PHE94L, PRO162L, PRO26L, PRO365K, PRO47K, PRO49K, PRO96L, SER101L, SER359K, SER415K, SER8L, THR144L, THR14L, THR185L, THR186L, THR187L, THR225K, THR241K, THR25L, THR419K, THR5L, TYR16L, TYR174K, TYR189L, TYR362K, TYR368K, TYR372K, TYR88L, VAL12L, VAL130L, VAL135L, VAL161L, VAL176K, VAL18L, VAL298K, VAL351K, VAL453K, VAL88K, VAL92L, VAL98L
• M-N: ALA102N, ALA104N, ALA145N, ALA14M, ALA163N, ALA175M, ALA19N, ALA221M, ALA226M, ALA231N, ALA232N, ALA239M, ALA23N, ALA367M, ALA371M, ALA375M, ALA421M, ALA46M, ALA7N, ARG133M, ARG148N, ARG159N, ARG15N, ARG178M, ARG353M, ARG361M, ARG363M, ARG416M, ARG48M, ARG86N, ASN132M, ASN141N, ASN179M, ASN17N, ASN235M, ASN237M, ASN374M, ASN97N, ASP103N, ASP134N, ASP137N, ASP156N, ASP15M, ASP160N, ASP173M, ASP180M, ASP354M, ASP360M, ASP364M, ASP373M, ASP3N, ASP424M, ASP89N, GLN222M, GLN305M, GLN366M, GLN89M, GLN90M, GLU131M, GLU132N, GLU134M, GLU165N, GLU170M, GLU21N, GLU230N, GLU27N, GLU316M, GLU413M, GLU418M, GLU450M, GLU50M, GLU6N, GLU90N, GLY133N, GLY139N, GLY158N, GLY230M, GLY232M, GLY410M, GLY52M, GLY91N, HIS129N, HIS136N, HIS240M, HIS318M, HIS87M, ILE138N, ILE142N, ILE229M, ILE242M, ILE85N, ILE93N, LEU106N, LEU136M, LEU13N, LEU146N, LEU157N, LEU177M, LEU20N, LEU233M, LEU234M, LEU238M, LEU24N, LEU2N, LEU352M, LEU355M, LEU358M, LEU412M, LEU414M, LEU87N, LEU95N, LEU9N, LYS10N, LYS169M, LYS22N, LYS236M, LYS350M, LYS411M, LYS420M, MET100N, MET166M, MET184N, MET188N, MET1N, MET356M, MET357M, MET99N, PHE135M, PHE172M, PHE228M, PHE417M, PHE48N, PHE4N, PHE94N, PRO162N, PRO26N, PRO365M, PRO47M, PRO49M, PRO96N, SER101N, SER359M, SER415M, SER8N, THR144N, THR14N, THR185N, THR186N, THR187N, THR225M, THR241M, THR25N, THR419M, THR5N, TYR16N, TYR174M, TYR189N, TYR362M, TYR368M, TYR372M, TYR88N, VAL12N, VAL130N, VAL135N, VAL161N, VAL166N, VAL176M, VAL18N, VAL298M, VAL351M, VAL453M, VAL88M, VAL92N, VAL98N
• M-O: ALA294M, ALA294O, ALA334M, ALA334O, ALA338M, ALA338O, ALA343M, ALA343O, ALA367M, ALA367O, ALA46M, ALA46O, ARG353M, ARG353O, ARG361M, ARG361O, ARG363M, ARG363O, ARG48M, ARG48O, ARG72M, ARG72O, ASN235M, ASN235O, ASN301M, ASN301O, ASN312M, ASN312O, ASN341M, ASN341O, ASN348M, ASN348O, ASN44M, ASN44O, ASP297M, ASP297O, ASP336M, ASP336O, ASP349M, ASP349O, ASP354M, ASP354O, ASP360M, ASP360O, ASP364M, ASP364O, CYS293M, CYS293O, CYS328M, CYS328O, CYS337M, CYS337O, GLN327M, GLN327O, GLN75M, GLN75O, GLU115M, GLU115O, GLU313M, GLU313O, GLU316M, GLU316O, GLU320M, GLU320O, GLU331M, GLU331O, GLU345M, GLU345O, GLU71M, GLU71O, GLU86M, GLU86O, GLY230M, GLY230O, GLY231M, GLY231O, GLY232M, GLY232O, GLY288M, GLY288O, GLY300M, GLY300O, GLY319M, GLY319O, GLY322M, GLY322O, GLY323M, GLY323O, GLY77M, GLY77O, HIS240M, HIS240O, HIS295M, HIS295O, HIS318M, HIS318O, LEU233M, LEU233O, LEU234M, LEU234O, LEU302M, LEU302O, LEU333M, LEU333O, LEU339M, LEU339O, LEU344M, LEU344O, LEU352M, LEU352O, LEU355M, LEU355O, LEU358M, LEU358O, LYS236M, LYS236O, LYS289M, LYS289O, LYS347M, LYS347O, LYS350M, MET299M, MET299O, MET304M, MET304O, MET340M, MET340O, MET356M, MET356O, MET357M, MET357O, MET70M, MET70O, MET73M, MET73O, PHE19M, PHE19O, PHE228M, PHE228O, PHE321M, PHE321O, PHE78M, PHE78O, PRO47M, PRO47O, PRO49M, PRO49O, PRO79M, PRO79O, SER291M, SER291O, SER296M, SER296O, SER314M, SER314O, SER330M, SER330O, SER359M, SER359O, THR290M, THR290O, THR292M, THR292O, THR324M, THR324O, THR325M, THR325O, THR332M, THR332O, THR342M, THR342O, THR346M, THR346O, TRP310M, TRP310O, TRP329M, TRP329O, TYR112M, TYR112O, TYR116M, TYR116O, TYR317M, TYR317O, TYR335M, TYR335O, TYR362O, TYR45M, TYR45O, VAL298M, VAL298O, VAL303M, VAL303O, VAL315M, VAL315O, VAL351M, VAL351O, VAL74M, VAL74O, VAL76M, VAL76O
• M-P: ALA19P, ALA213P, ALA338M, ALA343M, ALA36M, ALA7P, ALA80M, ARG15P, ARG48M, ARG64M, ARG72M, ASN17P, ASN215P, ASN341M, ASN348M, ASP114M, ASP217P, ASP3P, CYS337M, GLN216P, GLN75M, GLU115M, GLU320M, GLU345M, GLU50M, GLU56M, GLU61M, GLU63M, GLY117M, GLY212P, GLY319M, GLY323M, GLY37M, GLY77M, HIS113M, HIS256P, HIS258P, HIS318M, ILE118M, ILE81M, LEU13P, LEU183P, LEU20P, LEU2P, LEU339M, LEU344M, LEU9P, LYS10P, LYS119M, LYS11P, LYS257P, LYS347M, LYS57M, LYS60M, MET184P, MET188P, MET340M, MET70M, MET73M, PHE321M, PHE4P, PHE78M, PRO79M, SER8P, THR14P, THR185P, THR186P, THR324M, THR342M, THR346M, THR39M, THR5P, THR67M, TYR112M, TYR116M, TYR16P, TYR317M, TYR335M, TYR38M, VAL12P, VAL351M, VAL74M, VAL76M
• N-O: ALA19N, ALA213N, ALA334O, ALA338O, ALA343O, ALA36O, ALA7N, ALA80O, ARG15N, ARG48O, ARG64O, ARG72O, ASN17N, ASN215N, ASN341O, ASN348O, ASP114O, ASP217N, ASP3N, ASP68O, CYS337O, GLN216N, GLN75O, GLU115O, GLU320O, GLU33O, GLU345O, GLU50O, GLU56O, GLU61O, GLU63O, GLY117O, GLY20O, GLY212N, GLY319O, GLY323O, GLY37O, GLY77O, HIS113O, HIS256N, HIS258N, ILE118O, ILE81O, LEU13N, LEU183N, LEU20N, LEU2N, LEU339O, LEU344O, LEU9N, LYS10N, LYS119O, LYS11N, LYS257N, LYS347O, LYS57O, LYS60O, MET184N, MET340O, MET70O, MET73O, PHE321O, PHE4N, PHE78O, PRO79O, SER8N, THR14N, THR185N, THR186N, THR342O, THR346O, THR39O, THR5N, THR67O, TYR112O, TYR116O, TYR16N, TYR317O, TYR335O, TYR38O, VAL12N, VAL21O, VAL351O, VAL74O, VAL76O
• O-P: ALA102P, ALA104P, ALA131P, ALA145P, ALA14O, ALA163P, ALA175O, ALA19P, ALA221O, ALA226O, ALA231P, ALA232P, ALA239O, ALA23P, ALA367O, ALA371O, ALA421O, ALA46O, ALA7P, ARG133O, ARG148P, ARG159P, ARG15P, ARG178O, ARG353O, ARG361O, ARG363O, ARG416O, ARG48O, ARG86P, ASN132O, ASN141P, ASN179O, ASN17P, ASN235O, ASN237O, ASN374O, ASN97P, ASP103P, ASP134P, ASP137P, ASP15O, ASP160P, ASP173O, ASP180O, ASP354O, ASP360O, ASP364O, ASP373O, ASP3P, ASP89P, GLN222O, GLN305O, GLN366O, GLN89O, GLN90O, GLU131O, GLU132P, GLU134O, GLU165P, GLU170O, GLU21P, GLU230P, GLU27P, GLU316O, GLU413O, GLU418O, GLU450O, GLU50O, GLU6P, GLU90P, GLY133P, GLY139P, GLY158P, GLY212P, GLY230O, GLY232O, GLY410O, GLY52O, GLY91P, HIS129P, HIS136P, HIS240O, HIS318O, HIS87O, ILE138P, ILE142P, ILE229O, ILE242O, ILE85P, ILE93P, LEU136O, LEU13P, LEU146P, LEU157P, LEU177O, LEU183P, LEU20P, LEU233O, LEU234O, LEU238O, LEU24P, LEU2P, LEU352O, LEU355O, LEU358O, LEU412O, LEU414O, LEU87P, LEU95P, LEU9P, LYS10P, LYS140P, LYS169O, LYS22P, LYS236O, LYS350O, LYS411O, LYS420O, MET100P, MET166O, MET184P, MET188P, MET1P, MET356O, MET357O, MET99P, PHE135O, PHE172O, PHE228O, PHE417O, PHE48P, PHE4P, PHE94P, PRO162P, PRO26P, PRO365O, PRO47O, PRO49O, PRO96P, SER101P, SER359O, SER415O, SER8P, THR14P, THR185P, THR186P, THR187P, THR225O, THR241O, THR25P, THR419O, THR5P, TYR16P, TYR174O, TYR189P, TYR362O, TYR368O, TYR372O, TYR88P, VAL12P, VAL130P, VAL135P, VAL161P, VAL166P, VAL176O, VAL18P, VAL298O, VAL351O, VAL453O, VAL88O, VAL92P, VAL98P