2I2P

crystal structure of ribosome with messenger rna and the anticodon stem-loop of p-site trna. this file contains the 30s subunit of one 70s ribosome. the entire crystal structure contains two 70s ribosomes and is described in remark 400.

• Total interactions analyzed: 253
• Total true interactions: 23
• Strongest Interaction:
  • Chains: J-N
  • Int. Res.: 55
  • Norm. En. per Res.: -4.7721
• Hub Node: C(4)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
B-E	0.0	0.0	-5.9711	-5.9711	7	0	0	279	0	2	3
C-D	0.0	0.0	-0.0004	-0.0004	2	0	0	1	0	0	2
C-E	0.0	-19.0542	-11.8166	-30.8708	12	1	0	471	2	7	7
C-J	0.0	6.9347	-70.8054	-63.8707	56	0	3	3288	0	14	11
C-N	-14.5919	-18.4057	-248.81	-281.8075	80	24	5	10617	1	36	33
D-E	0.0	-27.842	-68.6135	-96.4555	45	3	0	2945	2	11	16
D-P	0.0	0.0	-0.5144	-0.5144	2	0	0	47	0	0	0
E-H	-10.0132	-18.351	-87.0601	-115.4244	52	8	1	3958	1	18	12
F-R	-30.2752	-10.3222	-154.01	-194.6073	64	18	4	6659	2	13	21
G-I	0.0	0.0	-6.8814	-6.8814	27	0	1	699	0	7	7
G-K	-15.031	0.0	-61.9707	-77.0017	30	18	2	2659	0	3	6
H-L	0.0	0.0	-4.0399	-4.0399	8	0	1	346	0	0	0
H-Q	-4.0368	0.0	-24.955	-28.9918	16	1	0	1319	0	3	8
I-J	0.0	-8.8523	-18.9794	-27.8317	17	3	0	964	0	8	11
I-N	0.0	0.0	-6.9023	-6.9023	8	0	0	368	0	0	2
J-N	-17.504	-36.8814	-208.081	-262.4664	55	30	6	8795	1	17	29
K-R	0.0	-6.9463	-12.9898	-19.9361	20	0	0	784	0	6	11
K-U	-42.6281	16.1013	-217.307	-243.8338	79	45	2	9914	1	33	40
L-Q	-10.5917	0.0	-41.092	-51.6837	20	4	4	1918	0	0	6
M-S	-20.3855	3.7349	-97.2668	-113.9174	44	9	1	3922	0	11	21
N-S	0.0	0.0	-31.6037	-31.6037	29	7	1	1909	0	6	9
O-Q	0.0	0.0	-3.1194	-3.1194	6	0	0	181	0	2	0
R-U	0.0	-19.1668	-17.9626	-37.1294	18	0	0	1462	0	12	11

Interface residues

• B-E: ARG68E, ASN177B, ASN69E, GLU174B, LEU178B, LYS104B, THR101B
• C-D: ARG43D, MET128C
• C-E: ALA57E, ARG130C, ARG131C, ARG53E, GLN60E, GLU165C, GLU54E, LYS134C, PRO56E, TRP166C, TYR167C, VAL55E
• C-J: ALA12J, ALA23C, ALA60C, ALA93J, ALA94J, ARG16J, ARG58C, ARG64C, ARG68J, ARG9J, ASN24C, ASP14J, ASP63J, ASP91J, ASP97J, GLN64J, GLU27C, GLU47J, GLU57C, GLU66J, GLY12C, GLY1C, GLY8C, GLY95J, HIS5C, HIS70J, ILE13C, ILE18J, ILE53J, ILE67J, ILE9C, LEU10J, LEU11C, LEU17J, LEU32C, LEU71J, LEU92J, LYS11J, LYS15C, PHE13J, PHE22C, PHE28C, PHE49J, PRO16C, PRO59C, SER19C, SER54J, THR20C, THR25C, THR69J, TRP17C, TRP21C, TYR65J, VAL14C, VAL4C, VAL96J
• C-N: ALA23C, ALA29C, ALA86N, ALA87N, ALA98N, ARG10C, ARG39C, ARG53C, ARG64N, ARG74N, ARG84N, ARG89N, ASN184C, ASN18C, ASN24C, ASN31C, ASN7C, ASP30C, ASP33C, ASP35C, CYS63N, GLN40C, GLN65N, GLU27C, GLU57C, GLU85N, GLU91N, GLY12C, GLY1C, GLY77N, GLY8C, GLY90N, GLY94N, HIS5C, ILE13C, ILE54C, ILE56C, ILE92N, ILE9C, LEU11C, LEU177C, LEU32C, LEU73N, LEU78N, LEU95N, LYS113C, LYS15C, LYS26C, LYS37C, LYS3C, LYS75N, LYS82N, LYS96N, LYS97N, MET88N, PHE22C, PHE28C, PHE36C, PHE72N, PHE76N, PRO16C, PRO6C, PRO93N, SER19C, SER34C, SER52C, SER79N, SER99N, THR185C, THR20C, THR25C, THR43C, THR66N, TRP17C, TRP21C, TYR183C, VAL4C, VAL51C, VAL55C, VAL83N
• D-E: ALA106E, ALA112E, ALA79D, ARG111E, ARG46D, ASN121E, ASN84D, ASN88D, ASP49D, GLN53D, GLU100E, GLU115E, GLU196D, GLU201D, GLU87D, GLY101E, GLY103E, GLY107E, GLY108E, GLY118E, GLY78E, GLY83D, GLY86D, HIS120E, HIS197D, ILE104E, ILE105E, ILE199D, LEU123E, LEU14E, LEU198D, LEU202D, LYS13E, LYS205D, SER204D, SER99E, THR102E, THR85D, TYR50D, TYR75D, VAL119E, VAL122E, VAL200D, VAL52D, VAL55E
• D-P: ARG127D, SER44P
• E-H: ALA101H, ALA129H, ALA153E, ALA154E, ALA69H, ALA96H, ARG156E, ASN145E, ASN147E, GLN66H, GLN81E, GLN96E, GLU150E, GLU41H, GLU42H, GLU46H, GLU72H, GLY157E, GLY43H, GLY97H, GLY99H, HIS82E, ILE100H, ILE45H, LEU39H, LEU98H, LYS155E, LYS158E, LYS40H, LYS63H, LYS68H, LYS93H, MET146E, MET151E, MET95H, PHE44H, PHE65H, PRO149E, PRO83E, PRO97E, SER148E, SER73H, THR111H, TYR127H, TYR64H, VAL128H, VAL152E, VAL38H, VAL70H, VAL71H, VAL84E, VAL94H
• F-R: ALA26R, ALA48F, ALA57F, ALA57R, ALA61R, ALA99F, ARG38F, ARG45F, ARG56R, ARG60R, ARG62R, ARG72R, ARG86F, ARG91F, ASN63F, ASP21R, ASP24R, ASP71R, GLN46F, GLN53R, GLU19R, GLU40F, GLU5F, GLU98F, HIS55F, HIS73R, ILE20R, ILE25R, ILE51F, ILE6F, ILE85F, LEU39F, LEU47F, LEU61F, LEU64R, LEU66R, LEU67R, LYS23R, LYS53F, LYS56F, LYS59R, LYS93F, MET62F, MET88F, MET90F, MET9F, PHE8F, PRO50F, PRO68R, SER100F, SER65R, SER87F, THR70R, TRP42F, TYR22R, TYR49F, TYR4F, TYR59F, TYR63R, TYR69R, VAL60F, VAL7F, VAL89F, VAL96F
• G-I: ALA100I, ALA43I, ARG108I, ARG11I, ARG40I, ARG44I, ARG48I, ARG79I, ARG9G, ASP14G, GLN49I, GLU39G, GLU41I, GLU52I, ILE11G, ILE71I, LEU12G, LYS16G, LYS35G, MET45I, PRO13G, PRO15G, SER36G, SER72I, THR37G, THR42I, VAL46I
• G-K: ALA146G, ALA149G, ALA151G, ALA61K, ALA62K, ARG142G, ARG55K, ARG97K, ASN147G, GLN63K, GLN85G, GLU145G, GLU67K, LYS148G, LYS56K, MET143G, PHE150G, PHE51K, PHE60K, PRO59K, PRO87G, SER54K, SER57K, SER82G, SER94K, THR58K, TYR84G, VAL64K, VAL74G, VAL86G
• H-L: ALA1L, ARG79H, ASN4L, GLY81H, LEU82H, PRO80H, THR2L, VAL3L
• H-Q: ARG79H, ARG83H, GLU123H, GLY34Q, GLY81H, ILE84H, LEU82H, LYS29Q, LYS35Q, LYS86H, PHE27Q, PHE36Q, PRO80H, SER78H, TYR33Q, TYR85H
• I-J: ALA61J, ARG112I, ARG123I, ARG62J, ASP60J, ASP63J, GLN64J, GLY116I, LEU117I, LEU52J, LYS113I, LYS114I, LYS59J, PRO124I, THR50J, VAL115I, VAL51J
• I-N: ALA98N, ARG112I, LYS113I, LYS114I, LYS97N, SER99N, TRP100N, VAL115I
• J-N: ALA12J, ALA61J, ALA87N, ALA98N, ARG45J, ARG48J, ARG62J, ARG68J, ARG68N, ARG74N, ARG80N, ARG84N, ASN58J, ASP14J, ASP63J, GLN64J, GLU47J, GLU66J, GLU85N, GLY71N, GLY94N, HIS56J, HIS70N, ILE53J, ILE67J, ILE81N, ILE92N, LEU17J, LEU52J, LEU73N, LEU78N, LEU95N, LYS46J, LYS59J, LYS75N, LYS82N, LYS96N, LYS97N, MET88N, PHE13J, PHE49J, PHE72N, PHE76N, PRO55J, PRO93N, SER54J, SER79N, SER99N, THR50J, THR69J, TRP100N, TYR65J, VAL51J, VAL57J, VAL83N
• K-R: ARG62R, ARG72R, ASN108K, ASP111K, ASP71R, HIS117K, HIS73R, ILE115K, LYS37R, LYS86K, MET84K, PRO114K, SER35R, THR110K, THR113K, THR70R, TYR63R, TYR69R, VAL112K, VAL85K
• K-U: ALA101K, ALA14U, ALA24K, ALA25U, ALA29U, ARG105K, ARG121K, ARG126K, ARG127K, ARG16U, ARG17U, ARG20U, ARG32U, ARG33U, ARG34U, ARG6U, ARG92K, ARG97K, ASN100K, ASN108K, ASN118K, ASN27K, ASN8U, ASP111K, ASP12U, CYS120K, CYS22U, GLU23U, GLU30U, GLU35U, GLU7U, GLU82K, GLU93K, GLY119K, GLY26U, GLY87K, GLY89K, GLY91K, ILE106K, ILE109K, ILE115K, ILE22K, ILE3U, ILE96K, LEU15U, LEU28U, LEU99K, LYS124K, LYS125K, LYS19U, LYS24U, LYS39U, LYS4U, LYS86K, MET84K, PHE11U, PHE26K, PHE36U, PRO10U, PRO114K, PRO116K, PRO122K, PRO123K, PRO88K, PRO90K, SER25K, SER94K, THR107K, THR110K, THR113K, TYR37U, VAL112K, VAL128K, VAL13U, VAL27U, VAL31U, VAL5U, VAL83K, VAL85K
• L-Q: ALA12L, ARG11L, ARG8L, ASN4L, GLN5L, GLY34Q, HIS30Q, ILE32Q, ILE37Q, LEU6L, LYS35Q, LYS38Q, LYS9L, PHE36Q, PRO10L, PRO31Q, THR2L, TYR33Q, VAL3L, VAL7L
• M-S: ALA74S, ARG100M, ARG2S, ARG35S, ARG77S, ARG78M, ARG80S, ARG86M, ARG89M, ARG91M, ARG92M, ARG97M, ASP81M, CYS84M, GLU64S, GLU72S, GLY71S, GLY83M, GLY87M, GLY93M, HIS68S, ILE39S, LEU70S, LEU79M, LEU82M, LEU88M, LEU94M, LYS102M, LYS69S, MET65S, MET80M, PHE60S, PHE73S, PRO75S, THR101M, THR62S, THR76S, THR78S, TYR79S, TYR85M, VAL57S, VAL59S, VAL61S, VAL96M
• N-S: ALA43N, ARG36S, ARG40N, ARG52N, ASN42N, ASN42S, ASP11S, ASP32N, GLN48N, GLU19S, GLY7S, HIS13S, ILE10S, LEU12S, LEU14S, LEU15S, LEU45N, LEU47N, LEU50N, LYS16S, LYS46N, LYS6S, PHE40S, PHE9S, PRO8S, SER31N, THR49N, VAL33N, VAL44N
• O-Q: ALA81Q, LYS70O, THR78O, TYR77O, VAL74O, VAL82Q
• R-U: ARG6U, ARG72R, ASP71R, CYS22U, GLU23U, GLU30U, GLU34R, GLY36R, HIS73R, ILE3U, LYS19U, LYS37R, LYS4U, PHE18U, SER35R, THR33R, THR70R, VAL27U