2HYE

crystal structure of the ddb1-cul4a-rbx1-sv5v complex

• Total interactions analyzed: 6
• Total true interactions: 3
• Strongest Interaction:
  • Chains: C-D
  • Int. Res.: 198
  • Norm. En. per Res.: -4.8692
• Hub Node: A(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-28.1465	-52.3469	-418.403	-498.8964	181	24	13	18054	2	48	54
A-C	-47.2334	-97.2586	-332.843	-477.335	206	59	6	17481	4	70	54
C-D	-189.651	-41.9641	-732.484	-964.0991	198	43	22	28184	5	64	66

Interface residues

• A-B: ALA133B, ALA381A, ALA776A, ALA813A, ALA834A, ALA841A, ALA869A, ALA956A, ALA971A, ARG1080A, ARG114A, ARG149B, ARG188A, ARG220B, ARG327A, ARG722A, ARG889A, ARG928A, ARG947A, ASN1005A, ASN1034A, ASN14B, ASN151B, ASN22B, ASN41B, ASN810A, ASN885A, ASN904A, ASN907A, ASN908A, ASN950A, ASN952A, ASN970A, ASP116B, ASP184A, ASP361A, ASP925A, ASP948A, CYS215B, GLN112B, GLN183A, GLN186A, GLN30B, GLN31B, GLN845A, GLU1002A, GLU117A, GLU138B, GLU146B, GLU147B, GLU150B, GLU18B, GLU217B, GLU219B, GLU25B, GLU312A, GLU787A, GLU811A, GLU839A, GLU840A, GLU842A, GLU969A, GLY119B, GLY125B, GLY129B, GLY187A, GLY20B, GLY34B, GLY357A, GLY380A, GLY39B, GLY46B, GLY868A, HIS163A, HIS778A, HIS789A, HIS905A, HIS991A, ILE13B, ILE17B, ILE359A, ILE43B, ILE740A, ILE909A, LEU115B, LEU117B, LEU122B, LEU132B, LEU16B, LEU21B, LEU328A, LEU38B, LEU814A, LEU912A, LEU926A, LEU931A, LYS1081A, LYS120B, LYS128B, LYS131B, LYS134B, LYS40B, LYS60A, LYS723A, LYS844A, LYS867A, MET835A, MET910A, MET927A, MET954A, PHE1003A, PHE27B, PHE382A, PHE771A, PHE949A, PHE972A, PRO115A, PRO123B, PRO148B, PRO152B, PRO185A, PRO358A, PRO44B, PRO45B, PRO721A, PRO777A, PRO81B, PRO838A, PRO843A, PRO951A, SER118B, SER124B, SER126B, SER216B, SER29B, SER36B, SER37B, SER720A, SER738A, SER773A, SER774A, SER815A, SER872A, SER886A, SER929A, SER955A, THR1032A, THR113B, THR118A, THR121B, THR19B, THR214B, THR23B, THR28B, THR33B, THR35B, THR42B, THR775A, THR833A, THR887A, THR901A, TRP953A, TYR127B, TYR26B, TYR812A, TYR837A, TYR871A, TYR906A, TYR913A, VAL1004A, VAL1006A, VAL1033A, VAL114B, VAL130B, VAL24B, VAL32B, VAL360A, VAL47B, VAL836A, VAL870A, VAL930A
• A-C: ALA400A, ALA501A, ALA511A, ALA515A, ALA539A, ALA610A, ALA756A, ALA760A, ALA862A, ALA89C, ARG144C, ARG150C, ARG158C, ARG179C, ARG434A, ARG49C, ARG514A, ARG51C, ARG53C, ARG589A, ARG655A, ARG713A, ARG80C, ASN164C, ASN439A, ASN47C, ASN497A, ASN677A, ASN695A, ASN696A, ASN82C, ASN92C, ASP157C, ASP172C, ASP223C, ASP279C, ASP403A, ASP453A, ASP454A, ASP50C, ASP608A, ASP654A, ASP795A, ASP855A, CYS143C, CYS540A, CYS94C, GLN163C, GLN225C, GLN283C, GLN432A, GLN455A, GLN456A, GLN634A, GLN759A, GLN859A, GLN88C, GLU398A, GLU441A, GLU442A, GLU444A, GLU445A, GLU447A, GLU47A, GLU537A, GLU585A, GLU675A, GLU800A, GLU84C, GLU85C, GLU863A, GLU91C, GLY219C, GLY406A, GLY409A, GLY431A, GLY513A, GLY559A, GLY584A, GLY607A, GLY609A, GLY632A, GLY856A, HIS280C, HIS399A, HIS536A, HIS797A, HIS803A, HIS96C, ILE147C, ILE149C, ILE152C, ILE402A, ILE407A, ILE45C, ILE498A, ILE564A, ILE586A, ILE587A, ILE701A, ILE79C, LEU154C, LEU156C, LEU162C, LEU175C, LEU404A, LEU425A, LEU427A, LEU436A, LEU438A, LEU43C, LEU54C, LEU560A, LEU606A, LEU699A, LEU717A, LEU761A, LEU802A, LEU83C, LEU858A, LEU86C, LEU93C, LYS228C, LYS284C, LYS408A, LYS41C, LYS42C, LYS46C, LYS496A, LYS674A, LYS769A, LYS857A, MET146C, MET148C, MET437A, PHE153C, PHE155C, PHE429A, PHE458A, PHE48C, PHE799A, PRO168C, PRO285C, PRO405A, PRO52C, PRO588A, PRO635A, PRO716A, PRO754A, SER151C, SER165C, SER169C, SER222C, SER281C, SER401A, SER428A, SER473A, SER499A, SER590A, SER653A, SER697A, SER755A, SER762A, SER763A, SER764A, SER767A, SER854A, SER95C, THR159C, THR166C, THR282C, THR433A, THR446A, THR562A, THR59C, THR62C, THR630A, THR633A, THR636A, THR700A, THR798A, THR860A, TRP171C, TRP561A, TYR160C, TYR227C, TYR58C, TYR678A, TYR687A, TYR718A, TYR81C, TYR87C, VAL430A, VAL435A, VAL443A, VAL44C, VAL500A, VAL512A, VAL538A, VAL637A, VAL715A, VAL765A, VAL801A, VAL850A, VAL861A, VAL90C
• C-D: ALA29D, ALA31D, ALA34D, ALA458C, ALA485C, ALA486C, ALA576C, ALA580C, ALA61D, ALA63D, ALA698C, ALA699C, ALA71D, ALA759C, ALA78D, ARG21D, ARG565C, ARG666C, ARG687C, ARG692C, ARG702C, ARG735C, ARG742C, ARG86D, ASN28D, ASN526C, ASN603C, ASN657C, ASN670C, ASN76D, ASP36D, ASP40D, ASP497C, ASP522C, ASP606C, ASP691C, ASP697C, ASP741C, ASP743C, CYS56D, CYS68D, CYS75D, CYS83D, GLN104D, GLN551C, GLN568C, GLN570C, GLN590C, GLN595C, GLN60D, GLN690C, GLN693C, GLN695C, GLN92D, GLU102D, GLU23D, GLU492C, GLU546C, GLU552C, GLU55D, GLU581C, GLU588C, GLU604C, GLU66D, GLU67D, GLU737C, GLY107D, GLY464C, GLY493C, GLY519C, GLY531C, GLY564C, GLY574C, GLY605C, GLY607C, GLY658C, GLY73D, HIS108D, HIS562C, HIS575C, HIS77D, HIS82D, ILE37D, ILE49D, ILE521C, ILE527C, ILE548C, ILE655C, ILE669C, ILE696C, ILE700C, ILE84D, LEU32D, LEU462C, LEU491C, LEU500C, LEU523C, LEU528C, LEU543C, LEU550C, LEU559C, LEU567C, LEU573C, LEU578C, LEU593C, LEU597C, LEU599C, LEU600C, LEU631C, LEU639C, LEU739C, LEU88D, LYS105D, LYS19D, LYS20D, LYS25D, LYS26D, LYS454C, LYS490C, LYS549C, LYS555C, LYS566C, LYS579C, LYS583C, LYS587C, LYS705C, LYS734C, LYS89D, MET494C, MET498C, MET505C, MET530C, MET547C, MET601C, MET745C, PHE103D, PHE22D, PHE487C, PHE554C, PHE582C, PHE589C, PHE602C, PHE656C, PHE660C, PHE81D, PRO520C, PRO534C, PRO538C, SER489C, SER501C, SER563C, SER592C, SER62D, SER65D, SER738C, SER85D, THR488C, THR524C, THR529C, THR535C, THR537C, THR544C, THR571C, THR572C, THR596C, THR64D, THR69D, THR90D, TRP101D, TRP27D, TRP33D, TRP35D, TRP533C, TRP569C, TRP72D, TRP87D, TYR106D, TYR532C, TYR536C, TYR558C, TYR694C, TYR744C, TYR757C, VAL24D, VAL30D, VAL38D, VAL39D, VAL463C, VAL525C, VAL577C, VAL591C, VAL598C, VAL638C, VAL688C, VAL701C, VAL70D, VAL74D, VAL758C