2HV2

crystal structure of conserved protein of unknown function from enterococcus faecalis v583 at 2.4 a resolution, probable n- acyltransferase

• Total interactions analyzed: 15
• Total true interactions: 12
• Strongest Interaction:
  • Chains: E-F
  • Int. Res.: 134
  • Norm. En. per Res.: -3.4139
• Hub Node: A(4)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-40.5376	20.4117	-372.988	-393.1138	138	21	5	14704	6	37	26
A-C	-14.8757	-15.4215	-126.993	-157.2901	63	8	0	4671	3	14	7
A-E	-12.7727	-36.1976	-128.01	-176.9803	63	11	0	4860	2	13	9
A-F	0.0	19.4797	-1.1112	18.3686	8	0	0	158	0	6	5
B-C	0.0	20.0553	-1.5453	18.51	6	0	0	189	0	6	5
B-D	-15.99	-28.5418	-120.263	-164.7948	62	18	0	4720	1	12	9
B-F	-9.2844	-29.8626	-126.039	-165.1861	62	12	0	4707	2	14	8
C-D	-67.4063	3.045	-398.173	-462.5343	138	22	5	15027	7	37	27
C-E	-9.3945	-40.9126	-129.88	-180.1871	65	9	0	4872	2	15	7
D-E	0.0	18.0971	-1.589	16.508	8	0	0	198	0	5	5
D-F	-30.154	-48.4229	-124.976	-203.5529	62	15	0	4817	3	15	8
E-F	-59.5961	-13.6665	-384.205	-457.4675	134	21	5	14536	8	37	25

Interface residues

• A-B: ALA134A, ALA134B, ALA235A, ALA235B, ALA260A, ALA260B, ALA272A, ALA272B, ALA273A, ALA273B, ARG123A, ARG123B, ARG174A, ARG174B, ARG361A, ARG361B, ARG371A, ARG371B, ASN172A, ASN172B, ASN229A, ASN233A, ASN233B, ASN265A, ASN265B, ASP263A, ASP263B, ASP266A, ASP266B, GLN129A, GLN129B, GLN133A, GLN133B, GLN173A, GLN173B, GLN298A, GLN355A, GLN355B, GLN380B, GLN384B, GLU128A, GLU128B, GLU132A, GLU132B, GLU135A, GLU135B, GLU211A, GLU211B, GLU364A, GLU364B, GLU370A, GLU370B, GLY261A, GLY261B, GLY359A, GLY359B, ILE277A, ILE277B, LEU231A, LEU231B, LEU264A, LEU264B, LEU267A, LEU267B, LEU278A, LEU278B, LEU366A, LEU366B, LYS237A, LYS237B, LYS262A, LYS262B, LYS276A, LYS276B, LYS388A, LYS388B, PHE117A, PHE117B, PHE121A, PHE121B, PHE131A, PHE131B, PHE236A, PHE236B, PHE259A, PHE259B, PHE368A, PHE368B, PRO116A, PRO116B, PRO120A, PRO120B, PRO269A, PRO269B, PRO271A, PRO271B, PRO279A, PRO279B, PRO391A, PRO391B, SER118A, SER118B, SER274A, SER274B, SER362A, SER362B, SER367A, SER367B, THR130A, THR130B, THR232A, THR232B, THR234A, THR234B, THR270A, THR270B, THR365A, THR365B, TRP228A, TRP228B, TRP255A, TRP255B, TYR119A, TYR119B, TYR136A, TYR136B, TYR230A, TYR230B, TYR280A, TYR280B, TYR360A, TYR360B, TYR369A, TYR369B, VAL149A, VAL149B, VAL275A, VAL275B
• A-C: ALA201C, ALA219C, ALA220C, ALA238C, ALA240C, ALA24A, ARG145C, ARG148C, ARG155C, ARG217C, ARG88A, ASN199C, ASN26A, ASP19A, GLN200C, GLN251C, GLN54A, GLU28A, GLU86A, GLU90A, GLY221C, GLY241C, GLY244C, GLY248C, GLY89A, GLY91A, HIS246C, ILE153C, ILE202C, ILE218C, ILE22A, ILE243C, LEU20A, LEU239C, LEU55A, LYS147C, LYS154C, LYS237C, LYS4A, PHE117A, PHE223C, PHE242C, PHE25A, PRO144C, PRO197C, PRO29A, PRO85A, SER118A, SER245C, SER247C, SER249C, SER83A, THR152C, THR222C, THR56A, TRP143C, TYR216C, TYR23A, TYR84A, TYR87A, VAL146C, VAL149C, VAL250C
• A-E: ALA201A, ALA219A, ALA220A, ALA238A, ALA240A, ALA24E, ARG145A, ARG148A, ARG155A, ARG217A, ARG88E, ASN199A, ASN26E, ASP19E, GLN200A, GLN54E, GLU28E, GLU86E, GLU90E, GLY221A, GLY241A, GLY244A, GLY248A, GLY89E, GLY91E, HIS246A, ILE153A, ILE202A, ILE218A, ILE22E, ILE243A, ILE51E, LEU20E, LEU239A, LEU55E, LYS147A, LYS154A, LYS237A, LYS4E, PHE117E, PHE223A, PHE242A, PHE25E, PRO144A, PRO197A, PRO85E, SER118E, SER245A, SER247A, SER249A, SER83E, THR152A, THR222A, THR56E, TYR203A, TYR216A, TYR23E, TYR84E, TYR87E, VAL146A, VAL149A, VAL156A, VAL250A
• A-F: ARG145A, ARG145F, ASP142A, ASP142F, GLU141A, GLU141F, LYS139A, LYS139F
• B-C: ASP142B, ASP142C, GLU141B, GLU141C, LYS139B, LYS139C
• B-D: ALA201B, ALA219B, ALA220B, ALA238B, ALA240B, ALA24D, ALA82D, ARG145B, ARG148B, ARG155B, ARG217B, ARG88D, ASN199B, ASN26D, ASP19D, GLN200B, GLN54D, GLU28D, GLU86D, GLU90D, GLY221B, GLY241B, GLY244B, GLY248B, GLY89D, GLY91D, HIS246B, ILE153B, ILE202B, ILE218B, ILE22D, ILE243B, LEU20D, LEU239B, LEU55D, LYS147B, LYS154B, LYS237B, LYS4D, PHE117D, PHE223B, PHE242B, PHE25D, PRO144B, PRO197B, PRO85D, SER118D, SER245B, SER247B, SER249B, SER83D, THR152B, THR222B, THR56D, TYR216B, TYR23D, TYR84D, TYR87D, VAL146B, VAL149B, VAL156B, VAL250B
• B-F: ALA201F, ALA219F, ALA220F, ALA238F, ALA240F, ALA24B, ARG145F, ARG148F, ARG155F, ARG217F, ARG88B, ASN199F, ASN26B, ASP19B, GLN200F, GLN54B, GLU28B, GLU86B, GLU90B, GLY221F, GLY241F, GLY244F, GLY248F, GLY89B, GLY91B, HIS246F, ILE153F, ILE202F, ILE218F, ILE22B, ILE243F, LEU20B, LEU239F, LEU55B, LYS147F, LYS154F, LYS237F, LYS4B, PHE117B, PHE223F, PHE242F, PHE25B, PRO144F, PRO197F, PRO29B, PRO85B, SER118B, SER245F, SER247F, SER249F, SER83B, THR152F, THR222F, THR56B, TYR216F, TYR23B, TYR84B, TYR87B, VAL146F, VAL149F, VAL156F, VAL250F
• C-D: ALA134C, ALA134D, ALA235C, ALA235D, ALA260C, ALA260D, ALA272C, ALA272D, ALA273C, ALA273D, ARG123C, ARG123D, ARG174C, ARG174D, ARG361C, ARG361D, ARG371C, ARG371D, ASN172C, ASN172D, ASN229C, ASN229D, ASN233C, ASN233D, ASN265C, ASN265D, ASP263C, ASP263D, ASP266C, ASP266D, GLN129C, GLN129D, GLN133C, GLN173C, GLN173D, GLN355C, GLN355D, GLN380D, GLN384D, GLU128C, GLU128D, GLU132C, GLU132D, GLU135C, GLU135D, GLU211C, GLU211D, GLU364C, GLU364D, GLU370C, GLU370D, GLY261C, GLY261D, GLY359C, GLY359D, ILE277C, ILE277D, LEU231C, LEU231D, LEU264C, LEU264D, LEU267C, LEU267D, LEU278C, LEU278D, LEU366C, LEU366D, LYS237C, LYS237D, LYS262C, LYS262D, LYS276C, LYS276D, LYS388C, LYS388D, PHE117C, PHE117D, PHE121C, PHE121D, PHE131C, PHE131D, PHE236C, PHE236D, PHE259C, PHE259D, PHE368C, PHE368D, PRO116C, PRO116D, PRO120C, PRO120D, PRO269C, PRO269D, PRO271C, PRO271D, PRO279C, PRO279D, PRO391C, PRO391D, SER118C, SER118D, SER274C, SER274D, SER362C, SER362D, SER367C, SER367D, THR130C, THR130D, THR137D, THR232C, THR232D, THR234C, THR234D, THR270C, THR270D, THR365C, THR365D, TRP228C, TRP228D, TRP255C, TRP255D, TYR119C, TYR119D, TYR136C, TYR136D, TYR230C, TYR230D, TYR280C, TYR280D, TYR360C, TYR360D, TYR369C, TYR369D, VAL149C, VAL149D, VAL275C, VAL275D
• C-E: ALA201E, ALA219E, ALA220E, ALA238E, ALA240E, ALA24C, ARG145E, ARG148E, ARG155E, ARG217E, ARG88C, ASN199E, ASN26C, ASP19C, GLN200E, GLN251E, GLN54C, GLU28C, GLU86C, GLU90C, GLY221E, GLY241E, GLY244E, GLY248E, GLY89C, GLY91C, HIS246E, ILE153E, ILE202E, ILE218E, ILE22C, ILE243E, ILE51C, LEU20C, LEU239E, LEU55C, LYS147E, LYS154E, LYS237E, LYS4C, PHE117C, PHE223E, PHE242E, PHE25C, PRO144E, PRO197E, PRO29C, PRO85C, SER118C, SER245E, SER247E, SER249E, SER83C, THR152E, THR222E, THR56C, TRP143E, TYR216E, TYR23C, TYR84C, TYR87C, VAL146E, VAL149E, VAL214E, VAL250E
• D-E: ASP142D, ASP142E, GLN251D, GLU141D, GLU141E, LYS139D, LYS139E, THR140D
• D-F: ALA201D, ALA219D, ALA220D, ALA238D, ALA240D, ALA24F, ARG145D, ARG148D, ARG155D, ARG217D, ARG88F, ASN199D, ASN26F, ASP19F, ASP52F, GLN200D, GLN54F, GLU86F, GLU90F, GLY221D, GLY241D, GLY244D, GLY248D, GLY89F, GLY91F, HIS246D, ILE153D, ILE202D, ILE218D, ILE22F, ILE243D, ILE51F, LEU20F, LEU239D, LEU55F, LYS147D, LYS154D, LYS237D, LYS4F, PHE117F, PHE223D, PHE242D, PHE25F, PRO144D, PRO85F, SER245D, SER247D, SER249D, SER83F, THR152D, THR222D, THR2F, THR56F, TRP143D, TYR216D, TYR23F, TYR84F, TYR87F, VAL146D, VAL149D, VAL156D, VAL250D
• E-F: ALA134E, ALA134F, ALA235E, ALA235F, ALA260E, ALA260F, ALA272E, ALA272F, ALA273E, ALA273F, ARG123E, ARG123F, ARG174E, ARG174F, ARG361E, ARG361F, ARG371E, ARG371F, ASN172E, ASN172F, ASN233E, ASN233F, ASN265E, ASN265F, ASP263E, ASP263F, ASP266E, ASP266F, GLN129E, GLN129F, GLN133E, GLN173E, GLN173F, GLN355E, GLN355F, GLN384E, GLU128E, GLU128F, GLU132E, GLU132F, GLU135E, GLU135F, GLU211E, GLU211F, GLU364E, GLU364F, GLU370E, GLU370F, GLY261E, GLY261F, GLY359E, GLY359F, ILE277E, ILE277F, LEU231E, LEU231F, LEU264E, LEU264F, LEU267E, LEU267F, LEU278E, LEU278F, LEU366E, LEU366F, LYS237E, LYS237F, LYS262E, LYS262F, LYS276E, LYS276F, LYS388F, PHE117E, PHE117F, PHE121E, PHE121F, PHE131E, PHE131F, PHE236E, PHE236F, PHE259E, PHE259F, PHE368E, PHE368F, PRO116E, PRO116F, PRO120E, PRO120F, PRO269E, PRO269F, PRO271E, PRO271F, PRO279E, PRO279F, PRO391E, PRO391F, SER118E, SER118F, SER274E, SER274F, SER362E, SER362F, SER367E, SER367F, THR130E, THR130F, THR137F, THR232E, THR232F, THR234E, THR234F, THR270E, THR270F, THR365E, THR365F, TRP228E, TRP228F, TRP255E, TRP255F, TYR119E, TYR119F, TYR136E, TYR136F, TYR230E, TYR230F, TYR280E, TYR280F, TYR360E, TYR360F, TYR369E, TYR369F, VAL149E, VAL149F, VAL275E, VAL275F