2HLE

structural and biophysical characterization of the ephb4-ephrinb2 protein protein interaction and receptor specificity.

• Total interactions analyzed: 1
• Total true interactions: 1
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 102
  • Norm. En. per Res.: -3.7508
• Hub Node: A(1)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-69.7341	-34.4539	-278.397	-382.585	102	17	2	11688	3	27	28

Interface residues

• A-B: ALA153A, ALA155A, ALA183A, ALA186A, ALA28A, ARG106B, ARG148A, ARG150A, ARG56A, ARG65A, ARG91A, ASN103B, ASN123B, ASN160A, ASP110B, ASP29A, ASP39A, ASP49A, ASP59B, ASP62A, ASP62B, CYS184A, CYS61A, GLN109B, GLN118B, GLN130B, GLN41A, GLN52A, GLU119B, GLU128B, GLU154A, GLU26A, GLU43A, GLU44A, GLU50A, GLU51A, GLU59A, GLU96A, GLY126B, GLY152A, GLY157A, GLY40A, GLY47A, GLY58B, HIS53A, ILE115B, ILE63B, ILE64B, LEU100A, LEU101B, LEU102B, LEU124B, LEU127B, LEU146A, LEU187A, LEU188A, LEU25A, LEU30A, LEU45A, LEU48A, LEU61B, LEU95A, LYS112B, LYS116B, LYS133B, LYS149A, LYS158A, LYS31A, LYS60B, MET185A, MET83B, MET94A, PHE113B, PHE117B, PHE120B, PHE129B, PHE92A, PRO100B, PRO101A, PRO122B, PRO151A, SER121B, SER46A, SER54A, SER99A, THR114B, THR147A, THR156A, THR27A, THR57A, THR93A, TRP125B, TRP42A, TYR135B, TYR58A, TYR82B, VAL111B, VAL159A, VAL55A, VAL60A, VAL63A, VAL81B