2HL5

crystal structure of the c-terminal domain of human eb1 in complex with the a49m mutant cap-gly domain of human dynactin-1 (p150-glued)

• Total interactions analyzed: 6
• Total true interactions: 5
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 109
  • Norm. En. per Res.: -5.391
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-C	-12.1378	-13.6691	-138.988	-164.795	49	2	1	4711	0	10	5
A-B	-59.0141	-53.2946	-475.308	-587.6167	109	12	29	19711	7	51	59
A-D	0.0	0.0	-15.8237	-15.8237	15	0	0	765	0	1	1
C-B	0.0	0.0	-16.5614	-16.5614	17	0	0	825	0	3	1
B-D	-10.9829	-14.4289	-139.05	-164.4618	51	3	1	4759	1	12	6

Interface residues

• A-C: ALA248A, ALA45C, ALA53C, ARG214A, ARG222A, ARG28C, ARG76C, ARG90C, ASN223A, ASP215A, ASP244A, ASP250A, GLN229A, GLN74C, GLN91C, GLU211A, GLU225A, GLU232A, GLY219A, GLY48C, GLY55C, ILE224A, ILE245A, LEU221A, LEU226A, LEU246A, LEU27C, LEU51C, LYS220A, LYS56C, MET49C, PHE216A, PHE218A, PHE52C, PHE79C, PHE88C, PRO26C, THR249A, THR50C, THR54C, TRP57C, TYR217A, TYR247A, TYR46C, TYR78C, VAL243A, VAL29C, VAL47C, VAL58C
• A-B: ALA194A, ALA194B, ALA248A, ALA248B, ARG214A, ARG214B, ARG222A, ARG222B, ARG241A, ARG241B, ASN201A, ASN201B, ASN223A, ASN223B, ASN231A, ASN231B, ASP209A, ASP209B, ASP215A, ASP215B, ASP236A, ASP236B, ASP244A, ASP244B, ASP250A, ASP250B, CYS228A, CYS228B, GLN198A, GLN198B, GLN199A, GLN199B, GLN229B, GLN240A, GLN240B, GLU195A, GLU195B, GLU208A, GLU208B, GLU211A, GLU211B, GLU213A, GLU213B, GLU225A, GLU225B, GLU230A, GLU230B, GLU234A, GLU234B, GLU251B, GLY219A, GLY219B, GLY252B, ILE224A, ILE224B, ILE227A, ILE227B, ILE242A, ILE242B, ILE245A, ILE245B, LEU196A, LEU196B, LEU203A, LEU203B, LEU205A, LEU205B, LEU210A, LEU210B, LEU221A, LEU221B, LEU226A, LEU226B, LEU239A, LEU239B, LEU246A, LEU246B, LYS204A, LYS204B, LYS212A, LYS212B, LYS220A, LYS220B, MET197A, MET197B, PHE216A, PHE216B, PHE218A, PHE218B, PRO237A, PRO237B, THR206A, THR206B, THR249A, THR249B, TYR217A, TYR217B, TYR247A, TYR247B, VAL200A, VAL200B, VAL202A, VAL202B, VAL207A, VAL207B, VAL238A, VAL238B, VAL243A, VAL243B
• A-D: ALA53D, GLU213A, GLY55D, ILE224A, LEU210A, LEU221A, LEU51D, LYS220A, MET49D, PHE216A, PHE52D, THR50D, THR54D, TYR217A, TYR78D
• C-B: ALA53C, ARG76C, GLN74C, GLU213B, GLU251B, GLY55C, ILE224B, LEU210B, LEU221B, LEU51C, LYS220B, MET49C, PHE216B, PHE52C, THR50C, THR54C, TYR217B
• B-D: ALA248B, ALA45D, ALA53D, ARG214B, ARG222B, ARG28D, ARG76D, ARG90D, ASN223B, ASP215B, ASP244B, ASP250B, GLN229B, GLN74D, GLN91D, GLU211B, GLU225B, GLU230B, GLU232B, GLY219B, GLY233B, GLY48D, GLY55D, GLY75D, ILE224B, ILE245B, LEU221B, LEU226B, LEU246B, LEU27D, LEU51D, LYS220B, LYS56D, MET49D, PHE216B, PHE218B, PHE52D, PHE79D, PRO26D, THR249B, THR50D, THR54D, TRP57D, TYR217B, TYR247B, TYR46D, TYR78D, VAL243B, VAL29D, VAL47D, VAL58D