2HL3

crystal structure of the a49m mutant cap-gly domain of human dynactin-1 (p150-glued) in complex with human eb1 c- terminal hexapeptide

• Total interactions analyzed: 3
• Total true interactions: 3
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 105
  • Norm. En. per Res.: -9.0838
• Hub Node: A(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-271.1375	-103.0707	-579.59	-953.7982	105	28	39	21093	8	20	27
A-C	-39.8174	-25.2226	-111.577	-176.617	30	3	4	3192	1	10	4
B-C	0.0	-5.0283	-8.0556	-13.0839	8	0	0	320	0	6	2

Interface residues

• A-B: ALA45A, ALA45B, ARG28A, ARG28B, ARG32A, ARG32B, ARG41A, ARG41B, ARG90A, ARG90B, ASP63A, ASP63B, CYS81B, GLN91A, GLN91B, GLN93A, GLN93B, GLN95A, GLN95B, GLU34A, GLU34B, GLU64A, GLU64B, GLY30A, GLY30B, GLY37A, GLY37B, GLY39A, GLY39B, GLY42A, GLY42B, GLY48A, GLY48B, GLY59A, GLY59B, GLY67A, GLY67B, GLY71B, HIS17A, HIS40A, HIS40B, HIS85A, HIS85B, ILE36A, ILE36B, ILE61A, ILE61B, ILE87A, ILE87B, ILE94A, ILE94B, LEU27A, LEU27B, LEU62A, LEU62B, LYS38A, LYS38B, LYS56A, LYS56B, LYS66A, LYS66B, LYS68A, LYS68B, LYS77B, MET18A, PHE79A, PHE79B, PHE88A, PHE88B, PHE97A, PHE97B, PRO26A, PRO26B, SER16A, SER19A, SER31A, SER31B, SER92A, SER92B, THR43A, THR43B, THR80B, TRP57A, TRP57B, TYR46A, TYR46B, TYR78B, VAL29A, VAL29B, VAL33A, VAL33B, VAL35A, VAL35B, VAL44A, VAL44B, VAL47A, VAL47B, VAL58A, VAL58B, VAL60A, VAL60B, VAL89A, VAL89B, VAL96A, VAL96B
• A-C: ALA53A, ARG90A, ASN69A, ASP70A, GLN74A, GLN93A, GLU266C, GLU267C, GLY59A, GLY67A, GLY71A, GLY86A, ILE87A, LEU62A, LYS66A, LYS68A, PHE52A, PHE79A, PHE88A, SER92A, THR50A, THR54A, THR72A, TRP57A, TYR268C, TYR78A, VAL58A, VAL60A, VAL73A, VAL89A
• B-C: GLU266C, GLU267C, GLY37B, GLY39B, HIS40B, ILE36B, LYS38B, VAL35B