2HAP

structure of a hap1-18/dna complex reveals that protein/dna interactions can have direct allosteric effects on transcriptional activation

• Total interactions analyzed: 6
• Total true interactions: 1
• Strongest Interaction:
  • Chains: C-D
  • Int. Res.: 92
  • Norm. En. per Res.: -5.2002
• Hub Node: C(1)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
C-D	-60.3031	-149.8184	-268.3	-478.4215	92	20	16	11990	15	71	80

Interface residues

• C-D: ALA101D, ALA104C, ALA104D, ALA90C, ARG118C, ARG118D, ARG120C, ARG120D, ARG59D, ARG63D, ARG68C, ARG70C, ARG78D, ASN112C, ASN112D, ASP111C, ASP111D, ASP75D, CYS67C, CYS84C, CYS93C, GLN83C, GLN98D, GLU102D, GLU103C, GLU103D, GLU105D, GLU107C, GLU107D, GLU113C, GLU113D, GLU119C, GLU119D, GLU125C, GLU125D, GLU97D, GLY88C, HIS91C, HIS94C, ILE66C, LEU108C, LEU108D, LEU109C, LEU109D, LEU114C, LEU114D, LEU117C, LEU117D, LEU124C, LEU124D, LEU128C, LEU128D, LEU62D, LEU77D, LEU92C, LYS106C, LYS106D, LYS110C, LYS110D, LYS115C, LYS115D, LYS116C, LYS116D, LYS122C, LYS122D, LYS126C, LYS126D, LYS130C, LYS130D, LYS69C, LYS71C, LYS76D, LYS86C, MET96C, MET96D, PRO79D, SER123C, SER123D, SER129C, SER129D, THR127C, THR127D, THR65C, THR85C, THR87C, THR99D, TRP100C, TRP100D, TYR95D, VAL121C, VAL121D, VAL89C