2HAK

catalytic and ubiqutin-associated domains of mark1/par-1

• Total interactions analyzed: 28
• Total true interactions: 12
• Strongest Interaction:
  • Chains: E-F
  • Int. Res.: 115
  • Norm. En. per Res.: -3.1952
• Hub Node: B(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-20.5783	-30.0761	-95.819	-146.4735	46	13	1	3947	3	6	10
A-D	-8.4427	-6.8798	-49.3629	-64.6854	40	0	0	2042	1	17	9
B-C	-14.8407	-47.3506	-67.9941	-130.1854	42	2	2	2455	2	20	17
B-D	0.0	-4.7378	-13.9196	-18.6574	28	0	0	1029	0	6	16
B-G	0.0	0.0	-14.3024	-14.3024	30	2	0	1091	0	5	8
C-D	-19.995	-16.5748	-106.552	-143.1218	62	8	1	4261	2	11	11
C-G	0.0	0.0	-0.1618	-0.1618	7	0	0	67	0	1	1
E-F	-54.6694	-19.152	-293.627	-367.4484	115	14	8	11200	2	21	24
E-H	-4.7619	-18.0543	-57.973	-80.7891	37	1	2	2049	1	15	12
F-G	-17.9335	-26.3135	-48.1175	-92.3645	45	4	0	2214	4	26	14
F-H	0.0	0.0	-6.8919	-6.8919	31	0	0	856	0	4	21
G-H	0.0	4.1043	-79.4178	-75.3135	37	0	1	3034	0	5	7

Interface residues

• A-B: ALA65A, ARG146B, ARG268B, ASN198A, ASN63A, ASN90A, ASP85A, GLN88A, GLU149B, GLU199A, GLU278B, GLY246B, GLY60A, GLY62A, ILE269B, ILE83A, ILE84A, LEU248B, LEU89A, LYS148B, LYS61A, LYS66A, LYS68A, LYS96A, MET147B, MET273B, PHE200A, PHE271B, PHE64A, PRO249B, PRO270B, SER197A, SER245B, SER247B, SER93A, THR201A, THR275B, THR58A, THR87A, THR92A, TYR241B, TYR267B, TYR272B, VAL202A, VAL244B, VAL67A
• A-D: ALA338D, ARG261A, ARG264A, ARG268A, ARG54D, ASN254A, ASN52D, ASP330D, ASP352D, GLN253A, GLN47D, GLU257A, GLU341D, GLU353D, GLY252A, GLY336D, GLY51D, HIS49D, HIS72D, ILE119D, ILE269A, ILE331D, ILE50D, LEU55D, LEU74D, LYS266A, MET332D, MET335D, PHE271A, PHE337D, PRO270A, PRO48D, THR334D, THR357D, TYR267A, TYR272A, TYR53D, VAL333D, VAL354D, VAL73D
• B-C: ALA338B, ARG146C, ARG261C, ARG264C, ARG268C, ASN52B, ASP340B, ASP352B, GLN253C, GLU120B, GLU122B, GLU257C, GLU260C, GLU278C, GLU341B, GLU353B, GLY336B, GLY51B, HIS72B, ILE119B, ILE269C, ILE342B, LEU74B, LYS123B, LYS266C, LYS86B, MET273C, MET332B, MET335B, PHE271C, PHE337B, PRO270C, SER274C, THR121B, THR124B, THR275C, THR334B, THR357B, TYR272C, VAL333B, VAL354B, VAL73B
• B-D: ALA65D, ASN63D, ASP85B, ASP85D, GLN47D, GLN56D, GLN88B, GLN88D, GLY62D, ILE59B, LEU55D, LEU89B, LYS123B, LYS57B, LYS57D, LYS61B, LYS61D, LYS66B, LYS66D, LYS68B, LYS68D, LYS86B, PHE64D, PRO48B, PRO48D, THR58B, THR58D, THR87B
• B-G: ARG292G, ARG99B, ASN288G, GLN168G, GLN95B, GLU230G, GLY228G, GLY293G, HIS167B, HIS167G, HIS173B, HIS173G, ILE171B, ILE171G, LEU287G, LEU94B, LYS169G, LYS96B, PHE98B, PRO218G, PRO229G, PRO289G, PRO91B, SER93B, THR92B, TYR170B, TYR170G, VAL172B, VAL172G, VAL231G
• C-D: ALA65C, ARG146D, ARG174C, ARG261D, ARG264D, ARG268D, ASN198C, ASN254C, ASN254D, ASN63C, ASN90C, ASP175C, ASP251D, ASP85C, GLN253C, GLN253D, GLN88C, GLU149D, GLU199C, GLU278D, GLY145D, GLY203C, GLY203D, GLY223C, GLY246D, GLY60C, GLY62C, ILE269D, ILE83C, ILE84C, LEU220C, LEU248D, LEU89C, LYS148D, LYS177C, LYS224C, LYS225C, LYS61C, LYS66C, LYS68C, LYS96C, MET147D, MET273D, PHE200C, PHE271D, PHE64C, PRO213C, PRO249D, PRO270D, SER197C, SER245D, SER247D, SER93C, THR201C, THR58C, TYR226C, TYR241D, TYR267D, TYR272D, VAL202C, VAL244D, VAL67C
• C-G: ARG264C, GLN95G, LEU287C, LYS266C, LYS291C, PRO91G, THR92G
• E-F: ALA143F, ALA178F, ALA216E, ALA65E, ARG146F, ARG174E, ARG259E, ARG261E, ARG261F, ARG268F, ASN198E, ASN204E, ASN204F, ASN254E, ASN254F, ASN63E, ASN63F, ASN90E, ASP139F, ASP175E, ASP207E, ASP207F, ASP251E, ASP251F, ASP85E, CYS210E, CYS210F, GLN253E, GLN253F, GLN88E, GLU149F, GLU199E, GLU257E, GLY145F, GLY203E, GLY203F, GLY211E, GLY211F, GLY223E, GLY246F, GLY252E, GLY252F, GLY60E, GLY62E, HIS144F, ILE269F, ILE59E, ILE83E, ILE84E, LEU141F, LEU206E, LEU206F, LEU220E, LEU243F, LEU248E, LEU248F, LEU255E, LEU255F, LEU258E, LEU258F, LEU89E, LYS148F, LYS177E, LYS205E, LYS205F, LYS224E, LYS225E, LYS256E, LYS256F, LYS61E, LYS61F, LYS66E, LYS68E, LYS96E, MET147F, MET273F, PHE138E, PHE138F, PHE200E, PHE209E, PHE209F, PHE221E, PHE221F, PHE250F, PHE271F, PHE64E, PRO213E, PRO213F, PRO214E, PRO214F, PRO249F, PRO270F, SER197E, SER212E, SER212F, SER245F, SER247F, SER93E, THR201E, THR208E, THR208F, THR242F, THR58E, TYR140F, TYR215F, TYR226E, TYR241F, TYR267F, TYR272F, VAL137F, VAL142F, VAL202E, VAL238F, VAL244F, VAL67E
• E-H: ALA338H, ARG146E, ARG261E, ARG264E, ARG268E, ASN52H, ASP340H, ASP352H, GLN253E, GLU122H, GLU257E, GLU278E, GLU341H, GLU353H, GLY336H, GLY51H, HIS72H, ILE119H, ILE269E, ILE342H, LEU74H, LYS123H, MET273E, MET332H, MET335H, PHE271E, PHE337H, PRO270E, SER274E, THR121H, THR275E, THR334H, THR357H, TYR272E, VAL333H, VAL354H, VAL73H
• F-G: ALA338F, ARG261G, ARG264G, ARG268G, ASN254G, ASN52F, ASP352F, GLN253G, GLN47F, GLU117F, GLU257G, GLU260G, GLU278G, GLU341F, GLU353F, GLY252G, GLY336F, GLY51F, HIS49F, HIS72F, ILE119F, ILE269G, ILE331F, ILE50F, LEU74F, LYS256G, LYS266G, LYS282G, LYS350F, MET332F, MET335F, PHE271G, PHE337F, PRO270G, PRO48F, THR121F, THR334F, THR357F, TYR241G, TYR267G, TYR272G, VAL118F, VAL333F, VAL354F, VAL73F
• F-H: ASN63F, ASN63H, ASP85F, GLN47F, GLN47H, GLN88F, GLN88H, GLY62F, HIS49H, ILE83F, LEU55H, LYS123F, LYS123H, LYS57F, LYS57H, LYS61F, LYS61H, LYS66F, LYS66H, LYS68F, LYS68H, PHE64F, PHE64H, PRO48F, PRO48H, THR124F, THR58F, THR58H, THR87F, TYR126F, TYR126H
• G-H: ALA65G, ARG146H, ARG268H, ASN198G, ASN63G, ASP251H, ASP85G, GLN88G, GLU149H, GLU278H, GLY246H, GLY60G, GLY62G, ILE269H, ILE83G, ILE84G, LEU248H, LYS148H, LYS61G, LYS66G, LYS68G, MET147H, MET273H, PHE271H, PHE64G, PRO249H, PRO270H, SER245H, SER247H, THR201G, THR58G, THR87G, TYR241H, TYR272H, VAL202G, VAL244H, VAL67G