2GYR

crystal structure of human artemin

• Total interactions analyzed: 15
• Total true interactions: 10
• Strongest Interaction:
  • Chains: C-E
  • Int. Res.: 38
  • Norm. En. per Res.: -1.4924
• Hub Node: C(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-87.3588	-74.3832	280.84	119.0981	149	40	18	19522	8	14	37
A-C	0.0	8.7955	-5.8177	2.9778	10	5	0	466	0	0	1
B-C	0.0	0.0	-9.56	-9.56	14	0	1	517	0	0	2
B-D	0.0	0.0	-0.1762	-0.1762	8	0	0	76	0	4	1
C-D	-64.5633	-84.592	295.628	146.4727	151	30	18	19612	8	15	36
C-E	-7.8001	-12.5074	-36.4024	-56.7099	38	1	2	1782	0	2	4
C-F	0.0	19.2362	-16.0302	3.206	16	13	0	955	0	3	4
D-E	0.0	0.0	-13.0625	-13.0625	22	4	0	983	0	1	3
D-F	0.0	0.0	-0.7301	-0.7301	8	0	0	114	0	0	3
E-F	-68.6637	-75.3024	302.18	158.214	152	25	18	19766	6	14	36

Interface residues

• A-B: ALA16A, ALA16B, ALA39A, ALA39B, ALA48A, ALA48B, ALA53A, ALA53B, ALA55A, ALA55B, ALA95A, ALA95B, ARG15A, ARG15B, ARG28A, ARG28B, ARG30A, ARG30B, ARG37A, ARG40A, ARG40B, ARG57A, ARG57B, ARG63A, ARG63B, ARG6A, ARG6B, ARG71A, ARG71B, ARG74A, ARG74B, ARG8A, ARG8B, ARG92A, ARG92B, ASP44A, ASP44B, ASP91A, ASP91B, CYS100A, CYS100B, CYS32A, CYS32B, CYS36A, CYS36B, CYS5A, CYS5B, CYS69A, CYS69B, CYS70A, CYS70B, CYS98B, GLN10A, GLN10B, GLN67A, GLN67B, GLU76A, GLU76B, GLY18A, GLY18B, GLY20A, GLY20B, GLY34A, GLY34B, GLY4A, GLY4B, GLY52A, GLY52B, GLY54A, GLY54B, GLY61A, GLY61B, HIS43A, HIS43B, LEU11A, LEU11B, LEU17A, LEU17B, LEU19A, LEU19B, LEU26A, LEU45A, LEU45B, LEU47A, LEU47B, LEU50A, LEU50B, LEU51A, LEU51B, LEU56A, LEU56B, LEU7A, LEU7B, LEU93A, LEU93B, PHE29A, PHE29B, PHE31A, PHE31B, PRO13A, PRO13B, PRO42A, PRO42B, PRO58A, PRO58B, PRO59A, PRO59B, PRO60A, PRO60B, PRO64A, PRO64B, PRO68A, PRO68B, PRO72A, PRO72B, SER33A, SER33B, SER35A, SER35B, SER41A, SER41B, SER46A, SER46B, SER49A, SER49B, SER62A, SER62B, SER66A, SER66B, SER94A, SER94B, SER9A, SER9B, THR96A, THR96B, TYR75A, TYR75B, VAL12A, VAL12B, VAL14A, VAL14B, VAL27A, VAL27B, VAL65A, VAL65B, VAL78A, VAL78B, VAL90A, VAL90B
• A-C: ALA55C, ARG57A, ARG57C, GLY54C, LEU56A, LEU56C, PRO58A, PRO58C, PRO59A, PRO60A
• B-C: ALA53C, ALA55C, ARG28B, ARG57C, GLN10B, GLY52C, GLY54C, LEU11B, LEU26B, LEU50C, LEU51C, PHE31B, SER49C, SER9B
• B-D: ALA16D, ARG15D, ARG22D, ASP24B, GLU25B, LEU11B, LEU26B, PRO13D
• C-D: ALA16C, ALA16D, ALA39C, ALA39D, ALA48C, ALA48D, ALA53C, ALA53D, ALA55C, ALA55D, ALA95C, ALA95D, ALA97D, ARG15C, ARG15D, ARG28C, ARG28D, ARG30C, ARG30D, ARG37C, ARG37D, ARG40C, ARG40D, ARG57C, ARG57D, ARG63C, ARG63D, ARG6C, ARG6D, ARG71C, ARG71D, ARG74C, ARG74D, ARG8C, ARG8D, ARG92C, ARG92D, ASP44C, ASP44D, ASP91C, ASP91D, CYS100C, CYS100D, CYS32C, CYS32D, CYS36C, CYS36D, CYS5C, CYS5D, CYS69C, CYS69D, CYS70C, CYS70D, CYS98D, GLN10C, GLN10D, GLN67C, GLN67D, GLU76C, GLU76D, GLY18C, GLY18D, GLY20C, GLY34C, GLY34D, GLY4C, GLY4D, GLY52C, GLY52D, GLY54C, GLY54D, GLY61C, GLY61D, HIS43C, HIS43D, LEU11C, LEU11D, LEU17C, LEU17D, LEU19C, LEU19D, LEU26C, LEU26D, LEU45C, LEU45D, LEU47C, LEU47D, LEU50C, LEU50D, LEU51C, LEU51D, LEU56C, LEU56D, LEU7C, LEU7D, LEU93C, LEU93D, PHE29C, PHE29D, PHE31C, PHE31D, PRO13C, PRO13D, PRO42C, PRO42D, PRO58C, PRO58D, PRO59C, PRO59D, PRO60C, PRO60D, PRO64C, PRO64D, PRO68C, PRO68D, PRO72C, PRO72D, SER33C, SER33D, SER35C, SER35D, SER41C, SER41D, SER46C, SER46D, SER49C, SER49D, SER62C, SER62D, SER66C, SER66D, SER94C, SER94D, SER9C, SER9D, THR96C, THR96D, TYR75C, TYR75D, VAL12C, VAL12D, VAL14C, VAL14D, VAL27C, VAL27D, VAL65C, VAL65D, VAL78C, VAL78D, VAL90C, VAL90D
• C-E: ALA16C, ALA48E, ALA53E, ALA55E, ARG15C, ARG28C, ARG37E, ARG40E, ARG57E, ARG63E, ASP24C, GLN10C, GLN67E, GLU25C, GLY18C, GLY34E, GLY52E, GLY54E, LEU11C, LEU17C, LEU26C, LEU47E, LEU50E, LEU51E, LEU56E, PRO13C, PRO58E, PRO64E, SER23C, SER33E, SER35E, SER49E, SER62E, SER66E, SER9C, VAL12C, VAL14C, VAL27C
• C-F: ARG15C, ARG15F, ARG22C, ARG63F, ARG8C, GLY20C, GLY61F, HIS21C, LEU51F, PRO58F, PRO59F, PRO60F, PRO64F, SER62F, VAL65F, VAL83C
• D-E: ALA48D, ALA48E, ALA53D, ALA55D, ARG37E, ARG38E, ARG40E, ARG57D, ASP44E, GLN67E, GLY52D, GLY52E, GLY54D, LEU45E, LEU50D, LEU51D, LEU56D, PRO42E, SER35E, SER46E, SER49D, SER49E
• D-F: ARG15F, ARG57D, GLY18F, GLY20F, LEU17F, LEU19F, PRO58D, PRO60D
• E-F: ALA16E, ALA16F, ALA39E, ALA39F, ALA48E, ALA48F, ALA53E, ALA53F, ALA55E, ALA55F, ALA77F, ALA95E, ALA95F, ARG15E, ARG15F, ARG28E, ARG28F, ARG30E, ARG30F, ARG37E, ARG37F, ARG40E, ARG40F, ARG57E, ARG57F, ARG63E, ARG63F, ARG6E, ARG6F, ARG71E, ARG71F, ARG74E, ARG74F, ARG8E, ARG8F, ARG92E, ARG92F, ASP44E, ASP44F, ASP91E, ASP91F, CYS100E, CYS100F, CYS32E, CYS32F, CYS36E, CYS36F, CYS5E, CYS5F, CYS69E, CYS69F, CYS70E, CYS70F, CYS98F, GLN10E, GLN10F, GLN67E, GLN67F, GLU76E, GLU76F, GLY18E, GLY18F, GLY20E, GLY20F, GLY34E, GLY34F, GLY4E, GLY4F, GLY52E, GLY52F, GLY54E, GLY54F, GLY61E, GLY61F, HIS43E, HIS43F, LEU11E, LEU11F, LEU17E, LEU17F, LEU19E, LEU19F, LEU26E, LEU26F, LEU45E, LEU45F, LEU47E, LEU47F, LEU50E, LEU50F, LEU51E, LEU51F, LEU56E, LEU56F, LEU7E, LEU7F, LEU93E, LEU93F, PHE29E, PHE29F, PHE31E, PHE31F, PRO13E, PRO13F, PRO42E, PRO42F, PRO58E, PRO58F, PRO59E, PRO59F, PRO60E, PRO60F, PRO64E, PRO64F, PRO68E, PRO68F, PRO72E, PRO72F, SER33E, SER33F, SER35E, SER35F, SER41E, SER41F, SER46E, SER46F, SER49E, SER49F, SER62E, SER62F, SER66E, SER66F, SER94E, SER94F, SER9E, SER9F, THR96E, THR96F, TYR75E, TYR75F, VAL12E, VAL12F, VAL14E, VAL14F, VAL27E, VAL27F, VAL65E, VAL65F, VAL78E, VAL78F, VAL90E, VAL90F