2GTP

crystal structure of the heterodimeric complex of human rgs1 and activated gi alpha 1

• Total interactions analyzed: 6
• Total true interactions: 3
• Strongest Interaction:
  • Chains: B-C
  • Int. Res.: 89
  • Norm. En. per Res.: -3.4201
• Hub Node: A(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-C	0.0	0.0	-0.5997	-0.5997	11	0	0	111	0	0	3
A-D	-60.1329	-34.7346	-208.063	-302.9305	89	6	2	7744	2	61	49
B-C	-64.8019	-37.1329	-202.453	-304.3878	89	7	2	7770	2	62	54

Interface residues

• A-C: ASN166A, ASN84C, GLN80C, GLU63A, GLU64A, LEU186C, LEU190C, LEU61C, SER62A, THR81C, VAL60C
• A-D: ALA132D, ALA133D, ALA235A, ARG141D, ARG143D, ARG176D, ARG178A, ARG205A, ARG208A, ARG242A, ARG90A, ASN137D, ASN76A, ASN98D, ASP131D, ASP139D, ASP172D, ASP200A, ASP237A, CYS214A, GLN135D, GLN147A, GLN204A, GLN68A, GLN79A, GLU144D, GLU170D, GLU186A, GLU207A, GLU236A, GLU238A, GLU239A, GLU65A, GLU93D, GLU96D, GLU97D, GLY183A, GLY202A, GLY203A, GLY42A, HIS129D, HIS213A, ILE136D, ILE138D, ILE165D, ILE184A, ILE212A, ILE99D, LEU168D, LEU178D, LEU234A, LEU90D, LYS134D, LYS171D, LYS179D, LYS180A, LYS209A, LYS210A, LYS91D, MET169D, PHE127D, PHE140D, PHE199A, PHE86D, PHE89D, PHE94D, PRO175D, SER130D, SER173D, SER206A, SER47A, SER75A, SER92D, SER95D, THR142D, THR167D, THR181A, THR182A, THR187A, TRP211A, TYR174D, VAL128D, VAL164D, VAL179A, VAL185A, VAL201A, VAL233A, VAL50A, VAL72A
• B-C: ALA126C, ALA132C, ALA133C, ALA235B, ALA71B, ARG141C, ARG143C, ARG176C, ARG178B, ARG205B, ARG208B, ARG90B, ASN137C, ASN76B, ASN98C, ASP131C, ASP139C, ASP172C, ASP200B, ASP237B, CYS214B, GLN135C, GLN147B, GLN204B, GLN68B, GLN71C, GLU116B, GLU144C, GLU170C, GLU186B, GLU207B, GLU236B, GLU238B, GLU239B, GLU93C, GLU96C, GLU97C, GLY183B, GLY202B, GLY203B, GLY42B, HIS129C, HIS213B, ILE136C, ILE138C, ILE165C, ILE184B, ILE99C, LEU168C, LEU234B, LEU90C, LYS134C, LYS171C, LYS179C, LYS180B, LYS209B, LYS210B, LYS91C, MET169C, PHE127C, PHE140C, PHE199B, PHE89C, PHE94C, PRO175C, SER130C, SER173C, SER206B, SER47B, SER72C, SER75B, SER92C, SER95C, THR142C, THR167C, THR181B, THR182B, THR187B, TRP211B, TYR146B, TYR174C, VAL128C, VAL164C, VAL179B, VAL185B, VAL201B, VAL233B, VAL50B, VAL72B