2GPP

estrogen related receptor-gamma ligand binding domain complexed with a rip140 peptide and synthetic ligand gsk4716

• Total interactions analyzed: 6
• Total true interactions: 3
• Strongest Interaction:
  • Chains: A-C
  • Int. Res.: 44
  • Norm. En. per Res.: -3.5819
• Hub Node: A(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-46.5548	-98.921	-304.112	-449.5878	128	14	2	12333	8	50	39
A-C	-27.055	0.0	-130.547	-157.602	44	3	8	5813	0	4	4
B-D	-23.365	0.0	-137.897	-161.262	51	3	8	6301	0	4	4

Interface residues

• A-B: ALA348A, ALA348B, ALA373A, ALA373B, ALA375A, ALA375B, ALA398A, ALA398B, ALA414A, ALA414B, ARG412A, ARG412B, ARG413A, ARG413B, ARG425A, ARG425B, ASN346A, ASN346B, ASN347A, ASN347B, ASN376A, ASN376B, ASP344A, ASP344B, ASP378A, ASP378B, ASP393A, ASP393B, ASP401A, ASP401B, ASP410A, ASP410B, GLN351A, GLN351B, GLN389A, GLN389B, GLN392A, GLN392B, GLN400A, GLN400B, GLN426A, GLN426B, GLN433A, GLN433B, GLU307A, GLU307B, GLU383B, GLU386B, GLU397A, GLU397B, GLY415A, GLY415B, HIS381A, HIS381B, HIS396A, HIS396B, ILE349A, ILE349B, ILE372A, ILE372B, ILE382A, ILE382B, LEU343A, LEU343B, LEU350A, LEU350B, LEU352A, LEU352B, LEU369A, LEU369B, LEU391A, LEU391B, LEU395A, LEU395B, LEU399A, LEU399B, LEU418A, LEU418B, LEU421A, LEU421B, LEU423A, LEU423B, LEU424A, LEU424B, LYS354A, LYS354B, LYS355A, LYS355B, LYS390A, LYS390B, LYS416A, LYS416B, LYS430A, LYS430B, MET359A, MET359B, MET380A, MET380B, MET417A, MET417B, MET419A, MET419B, PRO411A, PRO411B, PRO422A, PRO422B, SER303A, SER303B, SER358A, SER358B, SER377A, SER377B, SER379A, SER379B, SER428A, SER428B, THR420A, THR420B, THR427A, THR427B, THR429A, THR429B, VAL385A, VAL385B, VAL388A, VAL388B, VAL394A, VAL394B
• A-C: ALA283A, ALA295A, ALA456A, ASP273A, ASP296A, GLN297A, GLN302A, GLN387C, GLU452A, GLY281A, HIS285A, HIS382C, HIS447A, ILE279A, ILE280A, LEU276A, LEU294A, LEU300A, LEU301A, LEU374A, LEU379C, LEU380C, LEU381C, LEU383C, LEU384C, LEU449A, LEU451A, LYS284A, LYS385C, LYS448A, MET298A, MET453A, PHE289A, PHE450A, SER290A, SER293A, SER299A, SER303A, SER378C, SER386C, THR388C, TRP305A, VAL277A, VAL278A
• B-D: ALA244B, ALA283B, ALA295B, ALA456B, ARG274B, ASP273B, ASP296B, GLN297B, GLN302B, GLN387D, GLU247B, GLU452B, GLY281B, HIS285B, HIS382D, HIS447B, ILE279B, ILE280B, ILE389D, LEU276B, LEU294B, LEU300B, LEU301B, LEU374B, LEU379D, LEU380D, LEU381D, LEU383D, LEU384D, LEU449B, LEU451B, LYS284B, LYS385D, LYS448B, MET298B, MET453B, PHE289B, PHE450B, PRO246B, PRO390D, SER290B, SER293B, SER299B, SER303B, SER378D, SER386D, THR388D, TRP282B, TRP305B, VAL277B, VAL278B