2GP7

estrogen related receptor-gamma ligand binding domain

• Total interactions analyzed: 6
• Total true interactions: 6
• Strongest Interaction:
  • Chains: C-D
  • Int. Res.: 125
  • Norm. En. per Res.: -3.1942
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-34.593	-56.5449	-289.089	-380.2269	125	10	1	12524	2	56	44
A-C	0.0	0.0	-0.668	-0.668	4	0	0	65	0	1	1
A-D	-15.8896	-49.2605	-56.9346	-122.0847	39	6	0	2686	3	24	21
B-C	-8.1063	-48.0467	-58.1081	-114.2612	41	0	0	2604	4	25	21
B-D	0.0	61.9864	-5.7885	56.1979	18	0	0	218	0	16	19
C-D	-50.262	-48.3178	-300.694	-399.2738	125	12	1	12885	2	54	44

Interface residues

• A-B: ALA348A, ALA348B, ALA373A, ALA373B, ALA375A, ALA375B, ALA398A, ALA398B, ALA414A, ALA414B, ARG412A, ARG412B, ARG413A, ARG413B, ARG425A, ARG425B, ASN347A, ASN347B, ASN376A, ASN376B, ASP344A, ASP344B, ASP378A, ASP378B, ASP393A, ASP393B, ASP401A, ASP401B, ASP410A, ASP410B, GLN351A, GLN351B, GLN389A, GLN389B, GLN392A, GLN392B, GLN400A, GLN400B, GLN426A, GLN426B, GLN433A, GLN433B, GLU307A, GLU307B, GLU383A, GLU383B, GLU386A, GLU386B, GLU397A, GLU397B, GLY415A, GLY415B, HIS381A, HIS381B, HIS396A, HIS396B, ILE372A, ILE372B, ILE382A, ILE382B, LEU352A, LEU352B, LEU369A, LEU369B, LEU391A, LEU391B, LEU395A, LEU395B, LEU399A, LEU399B, LEU418A, LEU418B, LEU421A, LEU421B, LEU423A, LEU423B, LEU424A, LEU424B, LYS354A, LYS354B, LYS355A, LYS355B, LYS390A, LYS390B, LYS416A, LYS416B, LYS430A, LYS430B, LYS457A, LYS457B, MET359A, MET359B, MET380A, MET380B, MET417A, MET417B, MET419A, MET419B, PRO411A, PRO411B, PRO422A, PRO422B, SER303A, SER303B, SER358A, SER358B, SER377A, SER377B, SER379A, SER379B, SER428A, SER428B, THR420A, THR420B, THR427A, THR427B, THR429A, THR429B, VAL385A, VAL385B, VAL388A, VAL388B, VAL394A, VAL394B, VAL458B
• A-C: ARG412A, ARG412C, PRO411A, PRO411C
• A-D: ALA387D, ALA398D, ALA404A, ARG412A, ARG413A, ASN235D, ASP384D, ASP393D, ASP401A, ASP401D, ASP410A, GLN400A, GLN406A, GLU362A, GLU397D, GLU409A, GLY288D, GLY405A, HIS240D, HIS285D, HIS407A, ILE237D, ILE286D, LEU241D, LEU292D, LEU391D, LEU395D, LYS236D, LYS360A, LYS390D, LYS416A, MET408A, PHE289D, PRO287D, PRO411A, SER239D, SER290D, THR291D, VAL394D
• B-C: ALA387B, ALA398B, ALA404C, ARG412C, ARG413C, ASN235B, ASP384B, ASP393B, ASP401B, ASP401C, ASP410C, GLN400C, GLN406C, GLU397B, GLU403C, GLU409C, GLY288B, GLY405C, HIS240B, HIS285B, HIS407C, ILE237B, ILE286B, LEU241B, LEU292B, LEU391B, LEU395B, LYS236B, LYS360C, LYS390B, LYS416C, MET408C, PHE289B, PRO287B, PRO411C, SER239B, SER290B, THR291B, VAL238B, VAL243B, VAL394B
• B-D: ASP393B, ASP393D, ASP401B, ASP401D, GLN400B, GLN400D, GLU386B, GLU386D, GLU397B, GLU397D, LYS236B, LYS236D, LYS390B, LYS390D, MET408D, PRO411B, PRO411D, TYR234B
• C-D: ALA348C, ALA348D, ALA373C, ALA373D, ALA375C, ALA375D, ALA398C, ALA398D, ALA414C, ALA414D, ARG412C, ARG412D, ARG413C, ARG413D, ARG425C, ARG425D, ASN347C, ASN347D, ASN376C, ASN376D, ASP344C, ASP344D, ASP378C, ASP378D, ASP393C, ASP393D, ASP401C, ASP401D, ASP410C, ASP410D, GLN351C, GLN351D, GLN389C, GLN389D, GLN392C, GLN392D, GLN400C, GLN400D, GLN426C, GLN426D, GLN433C, GLN433D, GLU307C, GLU307D, GLU383C, GLU383D, GLU386D, GLU397C, GLU397D, GLY415C, GLY415D, HIS381C, HIS381D, HIS396C, HIS396D, ILE372C, ILE372D, ILE382C, ILE382D, LEU343C, LEU343D, LEU352C, LEU352D, LEU369C, LEU369D, LEU391C, LEU391D, LEU395C, LEU395D, LEU399C, LEU399D, LEU418C, LEU418D, LEU421C, LEU421D, LEU423C, LEU423D, LEU424C, LEU424D, LYS354C, LYS354D, LYS355C, LYS355D, LYS390C, LYS390D, LYS416C, LYS416D, LYS430C, LYS430D, LYS457C, LYS457D, MET359C, MET359D, MET380C, MET380D, MET417C, MET417D, MET419C, MET419D, PRO411C, PRO411D, PRO422C, PRO422D, SER303C, SER303D, SER358C, SER358D, SER377C, SER377D, SER379C, SER379D, THR420C, THR420D, THR427C, THR427D, THR429C, THR429D, VAL385C, VAL385D, VAL388C, VAL388D, VAL394C, VAL394D, VAL458C, VAL458D