2GLJ

crystal structure of aminopeptidase i from clostridium acetobutylicum

• Total interactions analyzed: 276
• Total true interactions: 44
• Strongest Interaction:
  • Chains: A-I
  • Int. Res.: 191
  • Norm. En. per Res.: -4.4206
• Hub Node: E(4)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-D	-213.0734	-16.4111	-1074.5	-1303.9844	333	144	30	47377	4	126	109
A-E	-123.9759	-136.9438	-571.81	-832.7297	193	59	6	24599	14	104	84
A-I	-127.0279	-145.9904	-571.309	-844.3273	191	50	6	24185	14	104	83
B-C	-114.4475	-144.297	-574.568	-833.3125	193	56	6	24228	14	104	83
B-D	-98.792	-144.4727	-525.449	-768.7137	189	38	5	22626	13	103	84
B-K	-202.1104	-32.235	-1076.88	-1311.2254	336	143	29	47904	4	129	108
C-D	-132.1075	-132.0656	-563.495	-827.6681	192	54	6	24118	14	102	85
C-F	-202.9383	-18.5821	-1061.74	-1283.2604	332	144	28	47753	4	127	109
E-H	-185.6046	-33.1511	-1068.77	-1287.5257	332	143	29	47420	4	129	107
E-I	-97.0641	-145.7076	-543.701	-786.4727	189	52	5	23467	14	101	83
E-O	0.0	41.1681	0.0	41.1681	11	0	0	0	0	0	0
E-P	-5.9791	-1.4845			12
F-G	-95.2045	-148.7484	-561.527	-805.48	188	58	5	23777	13	102	85
F-H	-110.1506	-125.4412	-565.529	-801.1208	194	69	6	24731	14	104	85
G-H	-89.86	-153.9164	-541.897	-785.6734	188	52	6	23191	15	102	83
G-J	-181.7663	-28.9374	-1015.45	-1226.1537	331	129	29	46827	4	126	107
G-R	0.0	25.6073			9
H-M	0.0	0.0	-0.7932	-0.7932	6	0	0	59	0	6	6
H-O	0.0	10.7178	0.0	10.7178	8	0	0	0	0	0	0
H-P	0.0	0.0665			4
I-L	-191.5689	-19.6265	-1051.24	-1262.4354	329	140	29	47107	4	125	107
I-P	0.0	-5.5386			3
J-K	-74.8121	-134.3971	-485.124	-694.3332	177	35	5	20931	14	97	78
J-L	-107.2282	-129.6495	-553.371	-790.2487	188	57	6	24129	13	101	87
K-L	-105.997	-146.9222	-548.071	-800.9902	188	53	5	23565	14	102	85
L-O	0.0	-8.0763	0.0	-8.0763	3	0	0	0	0	0	0
M-P	-195.8917	-14.6532			73
M-Q	-108.7612	-146.8994			50
M-U	-77.3858	-146.6585			48
N-O	-109.2291	-131.9148	-67.7009	-308.8448	74	12	0	3090	1	12	11
N-P	-116.7454	-147.2735			50
N-W	-197.6755	-32.5227			68
O-P	-90.0772	-131.4282			50
O-R	-229.091	-13.2491			77
Q-T	-195.0842	-15.4201			73
Q-U	-96.5296	-130.0833			47
R-S	-113.4662	-125.3088			54
R-T	-135.6944	-154.6786			52
S-T	-101.0605	-150.9857			48
S-V	-199.6663	-20.9306			69
U-X	-187.1211	-30.6399			67
V-W	-105.6791	-133.2653			52
V-X	-96.5415	-147.1576			49
W-X	-104.6312	-145.0669			46

Interface residues

• A-D: ALA125A, ALA125D, ALA12A, ALA12D, ALA146A, ALA146D, ALA182A, ALA182D, ALA190A, ALA190D, ALA246A, ALA246D, ALA249A, ALA249D, ALA345A, ALA345D, ALA346A, ALA346D, ALA442A, ALA442D, ALA450A, ALA450D, ARG250A, ARG250D, ARG256A, ARG256D, ARG30A, ARG30D, ASN11A, ASN11D, ASN168A, ASN168D, ASN200A, ASN200D, ASN220A, ASN220D, ASN350A, ASN350D, ASN353A, ASN353D, ASN439A, ASN439D, ASP121A, ASP121D, ASP123A, ASP123D, ASP14A, ASP14D, ASP166A, ASP166D, ASP167A, ASP167D, ASP169A, ASP169D, ASP176A, ASP176D, ASP17A, ASP17D, ASP198A, ASP198D, ASP210A, ASP210D, ASP251A, ASP251D, ASP255A, ASP255D, ASP265A, ASP265D, ASP348A, ASP348D, ASP412A, ASP412D, ASP451A, ASP451D, CYS162A, CYS162D, GLN139A, GLN139D, GLN185A, GLN185D, GLN413A, GLN413D, GLU120A, GLU120D, GLU165A, GLU165D, GLU184A, GLU184D, GLU187A, GLU187D, GLU195A, GLU195D, GLU197A, GLU197D, GLU295A, GLU295D, GLU296A, GLU296D, GLU356A, GLU356D, GLU407A, GLU407D, GLU445A, GLU445D, GLU8D, GLY133A, GLY133D, GLY134A, GLY134D, GLY164A, GLY164D, GLY173A, GLY173D, GLY196D, GLY204A, GLY204D, GLY247A, GLY247D, GLY253A, GLY253D, GLY261A, GLY261D, GLY364A, GLY364D, GLY409A, GLY409D, GLY414A, GLY414D, GLY415A, GLY415D, GLY416A, GLY416D, GLY417A, GLY417D, HIS180A, HIS180D, HIS441A, HIS441D, ILE135A, ILE135D, ILE147A, ILE147D, ILE151A, ILE151D, ILE177A, ILE177D, ILE194A, ILE194D, ILE201A, ILE201D, ILE203A, ILE203D, ILE206A, ILE206D, ILE221A, ILE221D, ILE224A, ILE224D, ILE231A, ILE231D, ILE243D, ILE446A, ILE446D, LEU113A, LEU113D, LEU118A, LEU118D, LEU124A, LEU124D, LEU127A, LEU127D, LEU143A, LEU143D, LEU145A, LEU145D, LEU178A, LEU178D, LEU181A, LEU181D, LEU186A, LEU186D, LEU199A, LEU199D, LEU202A, LEU202D, LEU225A, LEU225D, LEU363A, LEU363D, LEU408A, LEU408D, LEU437A, LEU437D, LEU438A, LEU438D, LYS10A, LYS10D, LYS136A, LYS136D, LYS137A, LYS137D, LYS15A, LYS188A, LYS188D, LYS189A, LYS189D, LYS192A, LYS192D, LYS19A, LYS19D, LYS209A, LYS209D, LYS216A, LYS216D, LYS223A, LYS223D, LYS228A, LYS228D, LYS22A, LYS22D, LYS248A, LYS248D, LYS357A, LYS357D, LYS365A, LYS365D, LYS410A, LYS410D, LYS449A, LYS449D, MET126A, MET126D, MET222D, MET258A, MET258D, MET260A, MET260D, MET355A, MET355D, PHE172A, PHE172D, PHE236A, PHE236D, PHE254A, PHE254D, PHE25A, PHE347A, PHE347D, PHE34A, PHE34D, PRO109A, PRO109D, PRO144A, PRO144D, PRO170A, PRO170D, PRO207A, PRO207D, PRO245A, PRO245D, PRO349A, PRO349D, PRO352A, PRO352D, PRO443A, PRO443D, SER175A, SER175D, SER183A, SER183D, SER191A, SER191D, SER205A, SER205D, SER257A, SER257D, SER344A, SER344D, SER360D, SER447A, SER447D, SER448A, SER448D, THR122A, THR122D, THR142A, THR142D, TRP13A, TRP13D, TRP140A, TRP140D, TRP444A, TRP444D, TYR119A, TYR119D, TYR138A, TYR138D, TYR16A, TYR16D, TYR229A, TYR229D, TYR252A, TYR252D, TYR262A, TYR262D, TYR351A, TYR351D, TYR362A, TYR362D, VAL141A, VAL141D, VAL161A, VAL161D, VAL163A, VAL163D, VAL171A, VAL171D, VAL174A, VAL174D, VAL179A, VAL179D, VAL193A, VAL193D, VAL217A, VAL217D, VAL259A, VAL259D, VAL343A, VAL343D, VAL354A, VAL354D, VAL411A, VAL411D
• A-E: ALA190A, ALA239A, ALA302A, ALA315A, ALA332E, ALA384E, ALA390E, ALA406E, ALA420E, ALA424E, ALA78A, ARG110A, ARG330A, ARG330E, ARG358E, ARG376E, ARG393E, ARG394E, ARG42A, ARG81A, ASN116A, ASN220A, ASN226A, ASN312A, ASN335E, ASN359E, ASN370E, ASN382E, ASN385E, ASN59A, ASN79A, ASN80A, ASP112A, ASP121A, ASP155A, ASP198A, ASP230A, ASP235A, ASP293A, ASP316A, ASP383E, ASP412E, CYS381E, GLN115A, GLN215A, GLN306A, GLN404E, GLN413E, GLN429E, GLU120A, GLU128A, GLU195A, GLU197A, GLU213A, GLU233A, GLU234A, GLU240A, GLU242A, GLU295A, GLU296A, GLU311A, GLU326A, GLU326E, GLU356E, GLU387E, GLU391E, GLU407E, GLU425A, GLU425E, GLU8E, GLY133A, GLY134A, GLY149A, GLY156A, GLY196A, GLY298A, GLY301A, GLY304A, GLY374E, GLY377E, GLY380E, GLY409E, GLY414E, GLY417E, GLY427E, GLY82A, HIS130A, HIS219A, ILE135A, ILE151A, ILE158A, ILE194A, ILE221A, ILE231A, ILE300A, ILE317A, ILE389E, ILE395E, ILE422A, ILE422E, ILE431E, ILE63A, LEU111A, LEU113A, LEU118A, LEU127A, LEU208A, LEU241A, LEU327A, LEU327E, LEU329E, LEU333A, LEU333E, LEU392E, LEU396E, LEU408E, LEU423E, LEU5E, LEU6E, LYS114A, LYS136A, LYS137A, LYS153A, LYS154A, LYS188A, LYS214A, LYS216A, LYS218A, LYS223A, LYS294A, LYS308A, LYS328A, LYS328E, LYS331E, LYS357E, LYS371E, LYS378E, LYS398E, LYS410E, LYS7E, LYS83A, MET126A, MET222A, MET305A, MET318A, MET355E, MET428E, PHE236A, PHE309A, PHE310A, PHE310E, PHE369E, PRO109A, PRO117A, PRO386E, SER191A, SER232A, SER238A, SER299A, SER307A, SER360E, SER375E, SER379E, SER397E, THR129A, THR157A, THR303A, THR313A, THR373E, THR405E, THR418E, TRP403E, TYR119A, TYR131A, TYR132A, TYR138A, TYR334E, TYR362E, TYR372E, TYR388E, TYR421E, TYR426A, TYR426E, TYR9E, VAL150A, VAL152A, VAL193A, VAL217A, VAL237A, VAL297A, VAL314A, VAL411E, VAL430E
• A-I: ALA190I, ALA239I, ALA302I, ALA315I, ALA332A, ALA384A, ALA390A, ALA406A, ALA420A, ALA424A, ALA78I, ARG110I, ARG330A, ARG330I, ARG358A, ARG376A, ARG393A, ARG394A, ARG42I, ARG81I, ASN116I, ASN220I, ASN226I, ASN312I, ASN335A, ASN359A, ASN370A, ASN382A, ASN385A, ASN59I, ASN79I, ASN80I, ASP112I, ASP121I, ASP155I, ASP198I, ASP235I, ASP293I, ASP316I, ASP383A, ASP412A, CYS381A, GLN115I, GLN215I, GLN306I, GLN404A, GLN413A, GLN429A, GLU120I, GLU128I, GLU195I, GLU197I, GLU213I, GLU233I, GLU234I, GLU240I, GLU242I, GLU295I, GLU296I, GLU311I, GLU326A, GLU326I, GLU356A, GLU387A, GLU391A, GLU407A, GLU425A, GLU425I, GLU8A, GLY133I, GLY134I, GLY156I, GLY196I, GLY298I, GLY301I, GLY304I, GLY374A, GLY377A, GLY380A, GLY409A, GLY414A, GLY417A, GLY427A, GLY82I, HIS130I, HIS219I, ILE135I, ILE151I, ILE158I, ILE194I, ILE221I, ILE231I, ILE300I, ILE317I, ILE389A, ILE395A, ILE422A, ILE422I, ILE431A, ILE60I, ILE63I, LEU111I, LEU113I, LEU118I, LEU127I, LEU208I, LEU241I, LEU327A, LEU327I, LEU329A, LEU333A, LEU333I, LEU392A, LEU396A, LEU408A, LEU423A, LEU5A, LEU6A, LYS114I, LYS136I, LYS137I, LYS153I, LYS154I, LYS188I, LYS214I, LYS216I, LYS218I, LYS223I, LYS294I, LYS308I, LYS328A, LYS328I, LYS331A, LYS357A, LYS371A, LYS378A, LYS398A, LYS410A, LYS7A, LYS83I, MET126I, MET222I, MET305I, MET318I, MET355A, MET428A, PHE236I, PHE309I, PHE310A, PHE310I, PHE369A, PRO109I, PRO117I, PRO386A, SER191I, SER232I, SER238I, SER299I, SER307I, SER360A, SER375A, SER379A, SER397A, THR129I, THR157I, THR303I, THR313I, THR373A, THR405A, THR418A, TRP403A, TYR119I, TYR131I, TYR132I, TYR138I, TYR334A, TYR362A, TYR372A, TYR388A, TYR421A, TYR426A, TYR426I, TYR9A, VAL150I, VAL152I, VAL193I, VAL237I, VAL297I, VAL314I, VAL411A, VAL430A
• B-C: ALA190B, ALA239B, ALA302B, ALA315B, ALA332C, ALA384C, ALA390C, ALA406C, ALA420C, ALA424C, ALA78B, ARG110B, ARG330B, ARG330C, ARG358C, ARG376C, ARG393C, ARG394C, ARG42B, ARG81B, ASN116B, ASN220B, ASN226B, ASN312B, ASN335C, ASN359C, ASN370C, ASN382C, ASN385C, ASN59B, ASN79B, ASN80B, ASP112B, ASP121B, ASP155B, ASP198B, ASP230B, ASP235B, ASP293B, ASP316B, ASP383C, ASP412C, CYS381C, GLN115B, GLN215B, GLN306B, GLN404C, GLN413C, GLN429C, GLU120B, GLU128B, GLU195B, GLU197B, GLU213B, GLU227B, GLU233B, GLU234B, GLU240B, GLU242B, GLU295B, GLU296B, GLU311B, GLU326B, GLU326C, GLU356C, GLU387C, GLU391C, GLU407C, GLU425B, GLU425C, GLU8C, GLY133B, GLY134B, GLY156B, GLY196B, GLY298B, GLY301B, GLY304B, GLY374C, GLY377C, GLY380C, GLY409C, GLY414C, GLY417C, GLY427C, GLY82B, HIS130B, HIS219B, ILE135B, ILE151B, ILE158B, ILE194B, ILE221B, ILE224B, ILE231B, ILE300B, ILE317B, ILE389C, ILE395C, ILE422B, ILE422C, ILE431C, ILE63B, LEU111B, LEU113B, LEU118B, LEU127B, LEU208B, LEU225B, LEU241B, LEU327B, LEU327C, LEU329C, LEU333B, LEU333C, LEU392C, LEU396C, LEU408C, LEU423C, LEU5C, LEU6C, LYS114B, LYS136B, LYS137B, LYS153B, LYS154B, LYS188B, LYS216B, LYS218B, LYS223B, LYS294B, LYS308B, LYS328B, LYS328C, LYS331C, LYS357C, LYS371C, LYS378C, LYS398C, LYS410C, LYS7C, LYS83B, MET126B, MET222B, MET305B, MET318B, MET355C, MET428C, PHE236B, PHE309B, PHE310B, PHE310C, PHE369C, PRO109B, PRO117B, PRO386C, SER191B, SER232B, SER238B, SER299B, SER307B, SER360C, SER375C, SER379C, SER397C, THR129B, THR157B, THR303B, THR313B, THR373C, THR405C, THR418C, TRP403C, TYR119B, TYR131B, TYR132B, TYR138B, TYR334C, TYR362C, TYR372C, TYR388C, TYR421C, TYR426B, TYR426C, TYR9C, VAL150B, VAL152B, VAL193B, VAL237B, VAL297B, VAL314B, VAL411C, VAL430C
• B-D: ALA190D, ALA239D, ALA302D, ALA315D, ALA332B, ALA384B, ALA390B, ALA406B, ALA420B, ALA424B, ALA78D, ARG110D, ARG330B, ARG330D, ARG358B, ARG376B, ARG393B, ARG394B, ARG42D, ARG81D, ASN116D, ASN220D, ASN226D, ASN312D, ASN335B, ASN359B, ASN370B, ASN382B, ASN385B, ASN79D, ASN80D, ASP112D, ASP121D, ASP155D, ASP198D, ASP235D, ASP293D, ASP316D, ASP383B, ASP412B, CYS381B, GLN115D, GLN215D, GLN306D, GLN404B, GLN413B, GLN429B, GLU120D, GLU128D, GLU195D, GLU197D, GLU213D, GLU233D, GLU234D, GLU240D, GLU242D, GLU295D, GLU296D, GLU311D, GLU326B, GLU326D, GLU356B, GLU387B, GLU391B, GLU407B, GLU425B, GLU425D, GLU8B, GLY133D, GLY134D, GLY156D, GLY196D, GLY298D, GLY301D, GLY304D, GLY374B, GLY377B, GLY380B, GLY409B, GLY414B, GLY417B, GLY427B, GLY82D, HIS130D, HIS219D, ILE135D, ILE151D, ILE158D, ILE194D, ILE221D, ILE231D, ILE300D, ILE317D, ILE389B, ILE395B, ILE422B, ILE422D, ILE431B, ILE60D, ILE63D, LEU111D, LEU113D, LEU118D, LEU127D, LEU208D, LEU241D, LEU327B, LEU327D, LEU329B, LEU333B, LEU333D, LEU392B, LEU396B, LEU408B, LEU423B, LEU5B, LEU6B, LYS114D, LYS136D, LYS137D, LYS153D, LYS154D, LYS188D, LYS216D, LYS218D, LYS223D, LYS294D, LYS308D, LYS328B, LYS328D, LYS331B, LYS357B, LYS371B, LYS378B, LYS398B, LYS410B, LYS7B, LYS83D, MET126D, MET222D, MET305D, MET318D, MET355B, MET428B, PHE236D, PHE309D, PHE310B, PHE310D, PHE369B, PRO117D, PRO386B, SER191D, SER232D, SER238D, SER299D, SER307D, SER360B, SER375B, SER379B, SER397B, THR129D, THR157D, THR303D, THR313D, THR373B, THR405B, THR418B, TRP403B, TYR119D, TYR131D, TYR132D, TYR138D, TYR334B, TYR362B, TYR372B, TYR388B, TYR421B, TYR426B, TYR426D, TYR9B, VAL150D, VAL152D, VAL193D, VAL217D, VAL237D, VAL297D, VAL314D, VAL411B, VAL430B
• B-K: ALA125B, ALA125K, ALA12B, ALA12K, ALA146B, ALA146K, ALA182B, ALA182K, ALA190B, ALA190K, ALA246B, ALA246K, ALA249B, ALA249K, ALA345B, ALA345K, ALA346B, ALA346K, ALA442B, ALA442K, ALA450B, ALA450K, ARG250B, ARG250K, ARG256B, ARG256K, ARG30B, ARG30K, ASN11B, ASN11K, ASN168B, ASN168K, ASN200B, ASN200K, ASN220B, ASN220K, ASN350B, ASN350K, ASN353B, ASN353K, ASN439B, ASN439K, ASP121B, ASP121K, ASP123B, ASP123K, ASP14B, ASP14K, ASP166B, ASP166K, ASP167B, ASP167K, ASP169B, ASP169K, ASP176B, ASP176K, ASP17B, ASP17K, ASP198B, ASP198K, ASP210B, ASP210K, ASP251B, ASP251K, ASP255B, ASP255K, ASP265B, ASP265K, ASP348B, ASP348K, ASP412B, ASP412K, ASP451B, ASP451K, CYS162B, CYS162K, GLN139B, GLN139K, GLN185B, GLN185K, GLN413B, GLN413K, GLU120B, GLU120K, GLU165B, GLU165K, GLU184B, GLU184K, GLU187B, GLU187K, GLU195B, GLU195K, GLU197B, GLU197K, GLU212B, GLU295B, GLU295K, GLU296B, GLU296K, GLU356B, GLU356K, GLU407B, GLU407K, GLU445B, GLU445K, GLY133B, GLY133K, GLY134B, GLY134K, GLY164B, GLY164K, GLY173B, GLY173K, GLY196B, GLY196K, GLY204B, GLY204K, GLY247B, GLY247K, GLY253B, GLY253K, GLY261B, GLY261K, GLY364B, GLY364K, GLY409B, GLY409K, GLY414B, GLY414K, GLY415B, GLY415K, GLY416B, GLY416K, GLY417B, GLY417K, HIS180B, HIS180K, HIS441B, HIS441K, ILE135B, ILE135K, ILE147B, ILE147K, ILE151B, ILE151K, ILE177B, ILE177K, ILE194B, ILE194K, ILE201B, ILE201K, ILE203B, ILE203K, ILE206B, ILE206K, ILE221B, ILE221K, ILE224B, ILE224K, ILE231B, ILE231K, ILE243B, ILE243K, ILE446B, ILE446K, LEU113B, LEU113K, LEU118B, LEU118K, LEU124B, LEU124K, LEU127B, LEU127K, LEU143B, LEU143K, LEU145B, LEU145K, LEU178B, LEU178K, LEU181B, LEU181K, LEU186B, LEU186K, LEU199B, LEU199K, LEU202B, LEU202K, LEU225B, LEU225K, LEU363B, LEU363K, LEU408B, LEU408K, LEU437B, LEU437K, LEU438B, LEU438K, LYS10B, LYS10K, LYS136B, LYS136K, LYS137B, LYS137K, LYS15B, LYS188B, LYS188K, LYS189B, LYS189K, LYS192B, LYS192K, LYS19B, LYS19K, LYS209B, LYS209K, LYS216B, LYS216K, LYS223B, LYS223K, LYS228B, LYS228K, LYS22B, LYS22K, LYS248B, LYS248K, LYS357B, LYS357K, LYS365B, LYS365K, LYS410B, LYS410K, LYS449B, LYS449K, MET126B, MET126K, MET222K, MET258B, MET258K, MET260B, MET260K, MET355B, MET355K, PHE172B, PHE172K, PHE236B, PHE236K, PHE254B, PHE254K, PHE25B, PHE25K, PHE347B, PHE347K, PHE34B, PHE34K, PRO109B, PRO109K, PRO144B, PRO144K, PRO170B, PRO170K, PRO207B, PRO207K, PRO245B, PRO245K, PRO349B, PRO349K, PRO352B, PRO352K, PRO443B, PRO443K, SER175B, SER175K, SER183B, SER183K, SER191B, SER191K, SER205B, SER205K, SER257B, SER257K, SER344B, SER344K, SER360B, SER447B, SER447K, SER448B, SER448K, THR122B, THR122K, THR142B, THR142K, TRP13B, TRP13K, TRP140B, TRP140K, TRP444B, TRP444K, TYR119B, TYR119K, TYR138B, TYR138K, TYR16B, TYR16K, TYR229B, TYR229K, TYR252B, TYR252K, TYR262B, TYR262K, TYR351B, TYR351K, TYR362B, TYR362K, VAL141B, VAL141K, VAL161B, VAL161K, VAL163B, VAL163K, VAL171B, VAL171K, VAL174B, VAL174K, VAL179B, VAL179K, VAL193B, VAL193K, VAL217B, VAL217K, VAL259B, VAL259K, VAL343B, VAL343K, VAL354B, VAL354K, VAL411B, VAL411K
• C-D: ALA190C, ALA239C, ALA302C, ALA315C, ALA332D, ALA384D, ALA390D, ALA406D, ALA420D, ALA424D, ALA78C, ARG110C, ARG330C, ARG330D, ARG358D, ARG376D, ARG393D, ARG394D, ARG42C, ARG81C, ASN116C, ASN220C, ASN226C, ASN312C, ASN335D, ASN359D, ASN370D, ASN382D, ASN385D, ASN59C, ASN79C, ASN80C, ASP112C, ASP121C, ASP155C, ASP198C, ASP230C, ASP235C, ASP293C, ASP316C, ASP383D, ASP412D, CYS381D, GLN115C, GLN215C, GLN306C, GLN404D, GLN413D, GLN429D, GLU120C, GLU128C, GLU195C, GLU197C, GLU213C, GLU233C, GLU234C, GLU240C, GLU242C, GLU295C, GLU296C, GLU311C, GLU326C, GLU326D, GLU356D, GLU387D, GLU391D, GLU407D, GLU425C, GLU425D, GLU8D, GLY133C, GLY134C, GLY156C, GLY196C, GLY298C, GLY301C, GLY304C, GLY374D, GLY377D, GLY380D, GLY409D, GLY414D, GLY417D, GLY427D, GLY82C, HIS130C, HIS219C, ILE135C, ILE151C, ILE158C, ILE194C, ILE221C, ILE231C, ILE300C, ILE317C, ILE389D, ILE395D, ILE422C, ILE422D, ILE431D, ILE63C, LEU111C, LEU113C, LEU118C, LEU127C, LEU208C, LEU225C, LEU241C, LEU327C, LEU327D, LEU329D, LEU333C, LEU333D, LEU392D, LEU396D, LEU408D, LEU423D, LEU5D, LEU6D, LYS114C, LYS136C, LYS137C, LYS153C, LYS154C, LYS188C, LYS216C, LYS218C, LYS223C, LYS294C, LYS308C, LYS328C, LYS328D, LYS331D, LYS357D, LYS371D, LYS378D, LYS398D, LYS410D, LYS7D, LYS83C, MET126C, MET222C, MET305C, MET318C, MET355D, MET428D, PHE236C, PHE309C, PHE310C, PHE310D, PHE369D, PRO109C, PRO117C, PRO386D, SER191C, SER232C, SER238C, SER299C, SER307C, SER360D, SER375D, SER379D, SER397D, THR129C, THR157C, THR303C, THR313C, THR373D, THR405D, THR418D, TRP403D, TYR119C, TYR131C, TYR132C, TYR138C, TYR334D, TYR362D, TYR372D, TYR388D, TYR421D, TYR426C, TYR426D, TYR9D, VAL150C, VAL152C, VAL193C, VAL217C, VAL237C, VAL297C, VAL314C, VAL411D, VAL430D
• C-F: ALA125C, ALA125F, ALA12C, ALA12F, ALA146C, ALA146F, ALA182C, ALA182F, ALA190C, ALA190F, ALA246C, ALA246F, ALA249C, ALA249F, ALA345C, ALA345F, ALA346C, ALA346F, ALA442C, ALA442F, ALA450C, ALA450F, ARG250C, ARG250F, ARG256C, ARG256F, ARG30C, ARG30F, ASN11C, ASN11F, ASN168C, ASN168F, ASN200C, ASN200F, ASN220C, ASN220F, ASN350C, ASN350F, ASN353C, ASN353F, ASN439C, ASN439F, ASP121C, ASP121F, ASP123C, ASP123F, ASP14C, ASP14F, ASP166C, ASP166F, ASP167C, ASP167F, ASP169C, ASP169F, ASP176C, ASP176F, ASP17C, ASP17F, ASP198C, ASP198F, ASP210C, ASP210F, ASP251C, ASP251F, ASP255C, ASP255F, ASP265C, ASP265F, ASP348C, ASP348F, ASP412C, ASP412F, ASP451C, ASP451F, CYS162C, CYS162F, GLN139C, GLN139F, GLN185C, GLN185F, GLN413C, GLN413F, GLU120C, GLU120F, GLU165C, GLU165F, GLU184C, GLU184F, GLU187C, GLU187F, GLU195C, GLU195F, GLU197C, GLU197F, GLU295C, GLU295F, GLU296C, GLU296F, GLU356C, GLU356F, GLU407C, GLU407F, GLU445C, GLU445F, GLY133C, GLY133F, GLY134C, GLY134F, GLY164C, GLY164F, GLY173C, GLY173F, GLY196C, GLY204C, GLY204F, GLY247C, GLY247F, GLY253C, GLY253F, GLY261C, GLY261F, GLY364C, GLY364F, GLY409C, GLY409F, GLY414C, GLY414F, GLY415C, GLY415F, GLY416C, GLY416F, GLY417C, GLY417F, HIS180C, HIS180F, HIS441C, HIS441F, ILE135C, ILE135F, ILE147C, ILE147F, ILE151C, ILE151F, ILE177C, ILE177F, ILE194C, ILE194F, ILE201C, ILE201F, ILE203C, ILE203F, ILE206C, ILE206F, ILE221C, ILE221F, ILE224C, ILE224F, ILE231C, ILE231F, ILE243C, ILE446C, ILE446F, LEU113C, LEU113F, LEU118C, LEU118F, LEU124C, LEU124F, LEU127C, LEU127F, LEU143C, LEU143F, LEU145C, LEU145F, LEU178C, LEU178F, LEU181C, LEU181F, LEU186C, LEU186F, LEU199C, LEU199F, LEU202C, LEU202F, LEU225C, LEU225F, LEU363C, LEU363F, LEU408C, LEU408F, LEU437C, LEU437F, LEU438C, LEU438F, LYS10C, LYS10F, LYS136C, LYS136F, LYS137C, LYS137F, LYS188C, LYS188F, LYS189C, LYS189F, LYS192C, LYS192F, LYS19C, LYS19F, LYS209C, LYS209F, LYS216C, LYS216F, LYS223C, LYS223F, LYS228C, LYS228F, LYS22C, LYS22F, LYS248C, LYS248F, LYS357C, LYS357F, LYS365C, LYS365F, LYS410C, LYS410F, LYS449C, LYS449F, MET126C, MET126F, MET222C, MET258C, MET258F, MET260C, MET260F, MET355C, MET355F, PHE172C, PHE172F, PHE236C, PHE236F, PHE254C, PHE254F, PHE25C, PHE25F, PHE347C, PHE347F, PHE34C, PHE34F, PRO109C, PRO109F, PRO144C, PRO144F, PRO170C, PRO170F, PRO207C, PRO207F, PRO245C, PRO245F, PRO349C, PRO349F, PRO352C, PRO352F, PRO443C, PRO443F, SER175C, SER175F, SER183C, SER183F, SER191C, SER191F, SER205C, SER205F, SER257C, SER257F, SER344C, SER344F, SER360C, SER447C, SER447F, SER448C, SER448F, THR122C, THR122F, THR142C, THR142F, TRP13C, TRP13F, TRP140C, TRP140F, TRP444C, TRP444F, TYR119C, TYR119F, TYR138C, TYR138F, TYR16C, TYR16F, TYR229C, TYR229F, TYR252C, TYR252F, TYR262C, TYR262F, TYR351C, TYR351F, TYR362C, TYR362F, VAL141C, VAL141F, VAL161C, VAL161F, VAL163C, VAL163F, VAL171C, VAL171F, VAL174C, VAL174F, VAL179C, VAL179F, VAL193C, VAL193F, VAL217C, VAL217F, VAL259C, VAL259F, VAL343C, VAL343F, VAL354C, VAL354F, VAL411C, VAL411F
• E-H: ALA125E, ALA125H, ALA12E, ALA12H, ALA146E, ALA146H, ALA182E, ALA182H, ALA190E, ALA190H, ALA246E, ALA246H, ALA249E, ALA249H, ALA345E, ALA345H, ALA346E, ALA346H, ALA442E, ALA442H, ALA450E, ALA450H, ARG250E, ARG250H, ARG256E, ARG256H, ARG30E, ARG30H, ASN11E, ASN11H, ASN168E, ASN168H, ASN200E, ASN200H, ASN220E, ASN220H, ASN350E, ASN350H, ASN353E, ASN353H, ASN439E, ASN439H, ASP121E, ASP121H, ASP123E, ASP123H, ASP14E, ASP14H, ASP166E, ASP166H, ASP167E, ASP167H, ASP169E, ASP169H, ASP176E, ASP176H, ASP17E, ASP17H, ASP198E, ASP198H, ASP210E, ASP210H, ASP251E, ASP251H, ASP255E, ASP255H, ASP265E, ASP265H, ASP348E, ASP348H, ASP412E, ASP412H, ASP451E, ASP451H, CYS162E, CYS162H, GLN139E, GLN139H, GLN185E, GLN185H, GLN413E, GLN413H, GLU120E, GLU120H, GLU165E, GLU165H, GLU184E, GLU184H, GLU187E, GLU187H, GLU195E, GLU195H, GLU197E, GLU197H, GLU295E, GLU295H, GLU296E, GLU296H, GLU356E, GLU356H, GLU407E, GLU407H, GLU445E, GLU445H, GLY133E, GLY133H, GLY134E, GLY134H, GLY164E, GLY164H, GLY173E, GLY173H, GLY196E, GLY196H, GLY204E, GLY204H, GLY247E, GLY247H, GLY253E, GLY253H, GLY261E, GLY261H, GLY364E, GLY364H, GLY409E, GLY409H, GLY414E, GLY414H, GLY415E, GLY415H, GLY416E, GLY416H, GLY417E, GLY417H, HIS180E, HIS180H, HIS441E, HIS441H, ILE135E, ILE135H, ILE147E, ILE147H, ILE151E, ILE151H, ILE177E, ILE177H, ILE194E, ILE194H, ILE201E, ILE201H, ILE203E, ILE203H, ILE206E, ILE206H, ILE221E, ILE221H, ILE224E, ILE224H, ILE231E, ILE231H, ILE243H, ILE446E, ILE446H, LEU113E, LEU113H, LEU118E, LEU118H, LEU124E, LEU124H, LEU127E, LEU127H, LEU143E, LEU143H, LEU145E, LEU145H, LEU178E, LEU178H, LEU181E, LEU181H, LEU186E, LEU186H, LEU199E, LEU199H, LEU202E, LEU202H, LEU225E, LEU225H, LEU363E, LEU363H, LEU408E, LEU408H, LEU437E, LEU437H, LEU438E, LEU438H, LYS10E, LYS10H, LYS136E, LYS136H, LYS137E, LYS137H, LYS188E, LYS188H, LYS189E, LYS189H, LYS192E, LYS192H, LYS19E, LYS19H, LYS209E, LYS209H, LYS216E, LYS216H, LYS223E, LYS223H, LYS228E, LYS228H, LYS22E, LYS22H, LYS248E, LYS248H, LYS357E, LYS357H, LYS365E, LYS365H, LYS410E, LYS410H, LYS449E, LYS449H, MET126E, MET126H, MET258E, MET258H, MET260E, MET260H, MET355E, MET355H, PHE172E, PHE172H, PHE236E, PHE236H, PHE254E, PHE254H, PHE25E, PHE25H, PHE347E, PHE347H, PHE34E, PHE34H, PRO109E, PRO109H, PRO144E, PRO144H, PRO170E, PRO170H, PRO207E, PRO207H, PRO245E, PRO245H, PRO349E, PRO349H, PRO352E, PRO352H, PRO443E, PRO443H, SER175E, SER175H, SER183E, SER183H, SER191E, SER191H, SER205E, SER205H, SER257E, SER257H, SER344E, SER344H, SER360E, SER447E, SER447H, SER448E, SER448H, THR122E, THR122H, THR142E, THR142H, TRP13E, TRP13H, TRP140E, TRP140H, TRP444E, TRP444H, TYR119E, TYR119H, TYR138E, TYR138H, TYR16E, TYR16H, TYR229E, TYR229H, TYR252E, TYR252H, TYR262E, TYR262H, TYR351E, TYR351H, TYR362E, TYR362H, VAL141E, VAL141H, VAL161E, VAL161H, VAL163E, VAL163H, VAL171E, VAL171H, VAL174E, VAL174H, VAL179E, VAL179H, VAL193E, VAL193H, VAL217E, VAL217H, VAL259E, VAL259H, VAL343E, VAL343H, VAL354E, VAL354H, VAL411E, VAL411H
• E-I: ALA190E, ALA239E, ALA302E, ALA315E, ALA332I, ALA384I, ALA390I, ALA406I, ALA420I, ALA424I, ARG110E, ARG330E, ARG330I, ARG358I, ARG376I, ARG393I, ARG394I, ARG42E, ARG81E, ASN116E, ASN220E, ASN226E, ASN312E, ASN335I, ASN359I, ASN370I, ASN382I, ASN385I, ASN59E, ASN79E, ASN80E, ASP112E, ASP121E, ASP155E, ASP198E, ASP235E, ASP293E, ASP316E, ASP383I, ASP412I, CYS381I, GLN115E, GLN215E, GLN306E, GLN404I, GLN413I, GLN429I, GLU120E, GLU128E, GLU195E, GLU197E, GLU213E, GLU233E, GLU234E, GLU240E, GLU242E, GLU295E, GLU296E, GLU311E, GLU326E, GLU326I, GLU356I, GLU387I, GLU391I, GLU407I, GLU425E, GLU425I, GLU8I, GLY133E, GLY134E, GLY156E, GLY196E, GLY298E, GLY301E, GLY304E, GLY374I, GLY377I, GLY380I, GLY409I, GLY414I, GLY417I, GLY427I, GLY82E, HIS130E, HIS219E, ILE135E, ILE151E, ILE158E, ILE194E, ILE221E, ILE231E, ILE300E, ILE317E, ILE389I, ILE395I, ILE422E, ILE422I, ILE431I, ILE63E, LEU111E, LEU113E, LEU118E, LEU127E, LEU208E, LEU241E, LEU327E, LEU327I, LEU329I, LEU333E, LEU333I, LEU392I, LEU396I, LEU408I, LEU423I, LEU5I, LEU6I, LYS10I, LYS114E, LYS136E, LYS137E, LYS153E, LYS154E, LYS188E, LYS216E, LYS218E, LYS223E, LYS294E, LYS308E, LYS328E, LYS328I, LYS331I, LYS357I, LYS371I, LYS378I, LYS398I, LYS410I, LYS7I, LYS83E, MET126E, MET222E, MET305E, MET318E, MET355I, MET428I, PHE236E, PHE309E, PHE310E, PHE310I, PHE369I, PRO117E, PRO386I, SER191E, SER232E, SER238E, SER299E, SER307E, SER360I, SER375I, SER379I, SER397I, THR129E, THR157E, THR303E, THR313E, THR373I, THR405I, THR418I, TRP403I, TYR119E, TYR131E, TYR132E, TYR138E, TYR334I, TYR362I, TYR372I, TYR388I, TYR421I, TYR426E, TYR426I, TYR9I, VAL150E, VAL152E, VAL193E, VAL217E, VAL237E, VAL297E, VAL314E, VAL411I, VAL430I
• E-O: ASP155O, ASP210E, ASP230O, ASP235O, GLU212E, GLU213E, GLU234O, LYS153O, LYS154O, LYS209E, LYS214E
• E-P: ARG393P, ARG394P, ASN226E, ASP155E, GLU213E, GLU227E, GLU399P, HIS219E, LYS209E, LYS281P, LYS398P, LYS7P
• F-G: ALA190F, ALA239F, ALA302F, ALA315F, ALA332G, ALA384G, ALA390G, ALA406G, ALA420G, ALA424G, ARG110F, ARG330F, ARG330G, ARG358G, ARG376G, ARG393G, ARG394G, ARG42F, ARG81F, ASN116F, ASN220F, ASN226F, ASN312F, ASN335G, ASN359G, ASN370G, ASN382G, ASN385G, ASN59F, ASN79F, ASN80F, ASP112F, ASP121F, ASP155F, ASP198F, ASP235F, ASP293F, ASP316F, ASP383G, ASP412G, CYS381G, GLN115F, GLN215F, GLN306F, GLN404G, GLN413G, GLN429G, GLU120F, GLU128F, GLU195F, GLU197F, GLU213F, GLU233F, GLU234F, GLU240F, GLU242F, GLU295F, GLU296F, GLU311F, GLU326F, GLU326G, GLU356G, GLU387G, GLU391G, GLU407G, GLU425F, GLU425G, GLU8G, GLY133F, GLY134F, GLY156F, GLY196F, GLY298F, GLY301F, GLY304F, GLY374G, GLY377G, GLY380G, GLY409G, GLY414G, GLY417G, GLY427G, GLY82F, HIS130F, HIS219F, ILE135F, ILE151F, ILE158F, ILE194F, ILE221F, ILE231F, ILE300F, ILE317F, ILE389G, ILE395G, ILE422F, ILE422G, ILE431G, ILE63F, LEU111F, LEU113F, LEU118F, LEU127F, LEU208F, LEU241F, LEU327F, LEU327G, LEU329G, LEU333F, LEU333G, LEU392G, LEU396G, LEU408G, LEU423G, LEU5G, LEU6G, LYS114F, LYS136F, LYS137F, LYS153F, LYS154F, LYS188F, LYS216F, LYS218F, LYS223F, LYS294F, LYS308F, LYS328F, LYS328G, LYS331G, LYS357G, LYS371G, LYS378G, LYS398G, LYS410G, LYS7G, LYS83F, MET126F, MET222F, MET305F, MET318F, MET355G, MET428G, PHE236F, PHE309F, PHE310F, PHE310G, PHE369G, PRO117F, PRO386G, SER191F, SER232F, SER238F, SER299F, SER307F, SER360G, SER375G, SER379G, SER397G, THR129F, THR157F, THR303F, THR313F, THR373G, THR405G, THR418G, TRP403G, TYR119F, TYR131F, TYR132F, TYR138F, TYR334G, TYR362G, TYR372G, TYR388G, TYR421G, TYR426F, TYR426G, TYR9G, VAL150F, VAL152F, VAL193F, VAL217F, VAL237F, VAL297F, VAL314F, VAL411G, VAL430G
• F-H: ALA190H, ALA239H, ALA302H, ALA315H, ALA332F, ALA384F, ALA390F, ALA406F, ALA420F, ALA424F, ARG110H, ARG330F, ARG330H, ARG358F, ARG376F, ARG393F, ARG394F, ARG42H, ARG81H, ASN116H, ASN220H, ASN226H, ASN312H, ASN335F, ASN359F, ASN370F, ASN382F, ASN385F, ASN59H, ASN79H, ASN80H, ASP112H, ASP121H, ASP155H, ASP198H, ASP230H, ASP235H, ASP293H, ASP316H, ASP383F, ASP412F, CYS381F, GLN115H, GLN215H, GLN306H, GLN404F, GLN413F, GLN429F, GLU120H, GLU128H, GLU195H, GLU197H, GLU213H, GLU227H, GLU233H, GLU234H, GLU240H, GLU242H, GLU295H, GLU296H, GLU311H, GLU326F, GLU326H, GLU356F, GLU387F, GLU391F, GLU407F, GLU425F, GLU425H, GLU8F, GLY133H, GLY134H, GLY156H, GLY196H, GLY298H, GLY301H, GLY304H, GLY374F, GLY377F, GLY380F, GLY409F, GLY414F, GLY417F, GLY427F, GLY82H, HIS130H, HIS219H, ILE135H, ILE151H, ILE158H, ILE194H, ILE221H, ILE224H, ILE231H, ILE300H, ILE317H, ILE389F, ILE395F, ILE422F, ILE422H, ILE431F, ILE60H, ILE63H, LEU111H, LEU113H, LEU118H, LEU127H, LEU208H, LEU225H, LEU241H, LEU327F, LEU327H, LEU329F, LEU333F, LEU333H, LEU392F, LEU396F, LEU408F, LEU423F, LEU5F, LEU6F, LYS114H, LYS136H, LYS137H, LYS153H, LYS154H, LYS188H, LYS216H, LYS218H, LYS223H, LYS294H, LYS308H, LYS328F, LYS328H, LYS331F, LYS357F, LYS371F, LYS378F, LYS398F, LYS410F, LYS7F, LYS83H, MET126H, MET222H, MET305H, MET318H, MET355F, MET428F, PHE236H, PHE309H, PHE310F, PHE310H, PHE369F, PRO109H, PRO117H, PRO386F, SER191H, SER232H, SER238H, SER299H, SER307H, SER360F, SER375F, SER379F, SER397F, THR129H, THR157H, THR303H, THR313H, THR373F, THR405F, THR418F, TRP403F, TYR119H, TYR131H, TYR132H, TYR138H, TYR334F, TYR362F, TYR372F, TYR388F, TYR421F, TYR426F, TYR426H, TYR9F, VAL150H, VAL152H, VAL193H, VAL217H, VAL237H, VAL297H, VAL314H, VAL411F, VAL430F
• G-H: ALA190G, ALA239G, ALA302G, ALA315G, ALA332H, ALA384H, ALA390H, ALA406H, ALA420H, ALA424H, ARG110G, ARG330G, ARG330H, ARG358H, ARG376H, ARG393H, ARG394H, ARG42G, ARG81G, ASN116G, ASN220G, ASN226G, ASN312G, ASN335H, ASN359H, ASN370H, ASN382H, ASN385H, ASN59G, ASN79G, ASN80G, ASP112G, ASP121G, ASP155G, ASP198G, ASP230G, ASP235G, ASP293G, ASP316G, ASP383H, ASP412H, CYS381H, GLN115G, GLN215G, GLN306G, GLN404H, GLN413H, GLN429H, GLU120G, GLU128G, GLU195G, GLU197G, GLU213G, GLU233G, GLU234G, GLU240G, GLU242G, GLU295G, GLU296G, GLU311G, GLU326G, GLU326H, GLU356H, GLU387H, GLU391H, GLU407H, GLU425G, GLU425H, GLU8H, GLY133G, GLY134G, GLY156G, GLY196G, GLY298G, GLY301G, GLY304G, GLY374H, GLY377H, GLY380H, GLY409H, GLY414H, GLY417H, GLY427H, GLY82G, HIS130G, HIS219G, ILE135G, ILE151G, ILE158G, ILE194G, ILE221G, ILE231G, ILE300G, ILE317G, ILE389H, ILE395H, ILE422G, ILE422H, ILE431H, ILE63G, LEU111G, LEU113G, LEU118G, LEU127G, LEU208G, LEU241G, LEU327G, LEU327H, LEU329H, LEU333G, LEU333H, LEU392H, LEU396H, LEU408H, LEU423H, LEU5H, LEU6H, LYS114G, LYS136G, LYS137G, LYS153G, LYS154G, LYS188G, LYS218G, LYS223G, LYS294G, LYS308G, LYS328G, LYS328H, LYS331H, LYS357H, LYS371H, LYS378H, LYS398H, LYS410H, LYS7H, LYS83G, MET126G, MET222G, MET305G, MET318G, MET355H, MET428H, PHE236G, PHE309G, PHE310G, PHE310H, PHE369H, PRO109G, PRO117G, PRO386H, SER191G, SER232G, SER238G, SER299G, SER307G, SER360H, SER375H, SER379H, SER397H, THR129G, THR157G, THR303G, THR313G, THR373H, THR405H, THR418H, TRP403H, TYR119G, TYR131G, TYR132G, TYR138G, TYR334H, TYR362H, TYR372H, TYR388H, TYR421H, TYR426G, TYR426H, TYR9H, VAL150G, VAL152G, VAL193G, VAL237G, VAL297G, VAL314G, VAL411H, VAL430H
• G-J: ALA125G, ALA125J, ALA12G, ALA12J, ALA146G, ALA146J, ALA182G, ALA182J, ALA190G, ALA190J, ALA246G, ALA246J, ALA249G, ALA249J, ALA345G, ALA345J, ALA346G, ALA346J, ALA442G, ALA442J, ALA450G, ALA450J, ARG250G, ARG250J, ARG256G, ARG256J, ARG30G, ARG30J, ASN11G, ASN11J, ASN168G, ASN168J, ASN200G, ASN200J, ASN220G, ASN220J, ASN350G, ASN350J, ASN353G, ASN353J, ASN439G, ASN439J, ASP121G, ASP121J, ASP123G, ASP123J, ASP14G, ASP14J, ASP166G, ASP166J, ASP167G, ASP167J, ASP169G, ASP169J, ASP176G, ASP176J, ASP17G, ASP17J, ASP198G, ASP198J, ASP210G, ASP210J, ASP251G, ASP251J, ASP255G, ASP255J, ASP265G, ASP265J, ASP348G, ASP348J, ASP412G, ASP412J, ASP451G, ASP451J, CYS162G, CYS162J, GLN139G, GLN139J, GLN185G, GLN185J, GLN413G, GLN413J, GLU120G, GLU120J, GLU165G, GLU165J, GLU184G, GLU184J, GLU187G, GLU187J, GLU195G, GLU195J, GLU197G, GLU197J, GLU295G, GLU295J, GLU296G, GLU296J, GLU356G, GLU356J, GLU407G, GLU407J, GLU445G, GLU445J, GLY133G, GLY133J, GLY134G, GLY134J, GLY164G, GLY164J, GLY173G, GLY173J, GLY196G, GLY204G, GLY204J, GLY247G, GLY247J, GLY253G, GLY253J, GLY261G, GLY261J, GLY364G, GLY364J, GLY409G, GLY409J, GLY414G, GLY414J, GLY415G, GLY415J, GLY416G, GLY416J, GLY417G, GLY417J, HIS180G, HIS180J, HIS441G, HIS441J, ILE135G, ILE135J, ILE147G, ILE147J, ILE151G, ILE151J, ILE177G, ILE177J, ILE194G, ILE194J, ILE201G, ILE201J, ILE203G, ILE203J, ILE206G, ILE206J, ILE221G, ILE221J, ILE224G, ILE224J, ILE231G, ILE231J, ILE243G, ILE243J, ILE446G, ILE446J, LEU113G, LEU113J, LEU118G, LEU118J, LEU124G, LEU124J, LEU127G, LEU127J, LEU143G, LEU143J, LEU145G, LEU145J, LEU178G, LEU178J, LEU181G, LEU181J, LEU186G, LEU186J, LEU199G, LEU199J, LEU202G, LEU202J, LEU225G, LEU225J, LEU363G, LEU363J, LEU408G, LEU408J, LEU437G, LEU437J, LEU438G, LEU438J, LYS10J, LYS136G, LYS136J, LYS137G, LYS137J, LYS188G, LYS188J, LYS189G, LYS189J, LYS192G, LYS192J, LYS19G, LYS19J, LYS209G, LYS209J, LYS216G, LYS216J, LYS223G, LYS223J, LYS228G, LYS228J, LYS22G, LYS22J, LYS248G, LYS248J, LYS357G, LYS357J, LYS365G, LYS365J, LYS410G, LYS410J, LYS449G, LYS449J, MET126G, MET126J, MET258G, MET258J, MET260G, MET260J, MET355G, MET355J, PHE172G, PHE172J, PHE236G, PHE236J, PHE254G, PHE254J, PHE25G, PHE25J, PHE347G, PHE347J, PHE34G, PHE34J, PRO109G, PRO109J, PRO144G, PRO144J, PRO170G, PRO170J, PRO207G, PRO207J, PRO245G, PRO245J, PRO349G, PRO349J, PRO352G, PRO352J, PRO443G, PRO443J, SER175G, SER175J, SER183G, SER183J, SER191G, SER191J, SER205G, SER205J, SER257G, SER257J, SER344G, SER344J, SER360J, SER447G, SER447J, SER448G, SER448J, THR122G, THR122J, THR142G, THR142J, TRP13G, TRP13J, TRP140G, TRP140J, TRP444G, TRP444J, TYR119G, TYR119J, TYR138G, TYR138J, TYR16G, TYR16J, TYR229G, TYR229J, TYR252G, TYR252J, TYR262G, TYR262J, TYR351G, TYR351J, TYR362G, TYR362J, VAL141G, VAL141J, VAL161G, VAL161J, VAL163G, VAL163J, VAL171G, VAL171J, VAL174G, VAL174J, VAL179G, VAL179J, VAL193G, VAL193J, VAL217G, VAL217J, VAL259G, VAL259J, VAL343G, VAL343J, VAL354G, VAL354J, VAL411G, VAL411J
• G-R: ASP155G, ASP17R, ASP18R, ASP230G, ASP235G, GLU23R, LYS153G, LYS154G, LYS19R
• H-M: ASP210M, GLN20H, GLU212M, GLU23H, LYS19H, LYS216M
• H-O: ASP18H, ASP210O, GLU212O, GLU213O, GLU227O, GLU399H, GLU8H, LYS398H
• H-P: ASP17H, GLU8P, LYS10P, LYS19H
• I-L: ALA125I, ALA125L, ALA12I, ALA12L, ALA146I, ALA146L, ALA182I, ALA182L, ALA190I, ALA190L, ALA246I, ALA246L, ALA249I, ALA249L, ALA345I, ALA345L, ALA346I, ALA346L, ALA442I, ALA442L, ALA450I, ALA450L, ARG250I, ARG250L, ARG256I, ARG256L, ARG30I, ARG30L, ASN11I, ASN11L, ASN168I, ASN168L, ASN200I, ASN200L, ASN220I, ASN220L, ASN350I, ASN350L, ASN353I, ASN353L, ASN439I, ASN439L, ASP121I, ASP121L, ASP123I, ASP123L, ASP14I, ASP14L, ASP166I, ASP166L, ASP167I, ASP167L, ASP169I, ASP169L, ASP176I, ASP176L, ASP17I, ASP17L, ASP198I, ASP198L, ASP210I, ASP210L, ASP251I, ASP251L, ASP255I, ASP255L, ASP265I, ASP265L, ASP348I, ASP348L, ASP412I, ASP412L, ASP451I, ASP451L, CYS162I, CYS162L, GLN139I, GLN139L, GLN185I, GLN185L, GLN413I, GLN413L, GLU120I, GLU120L, GLU165I, GLU165L, GLU184I, GLU184L, GLU187I, GLU187L, GLU195I, GLU195L, GLU197I, GLU197L, GLU295I, GLU295L, GLU296I, GLU296L, GLU356I, GLU356L, GLU407I, GLU407L, GLU445I, GLU445L, GLY133I, GLY133L, GLY134I, GLY134L, GLY164I, GLY164L, GLY173I, GLY173L, GLY196I, GLY196L, GLY204I, GLY204L, GLY247I, GLY247L, GLY253I, GLY253L, GLY261I, GLY261L, GLY364I, GLY364L, GLY409I, GLY409L, GLY414I, GLY414L, GLY415I, GLY415L, GLY416I, GLY416L, GLY417I, GLY417L, HIS180I, HIS180L, HIS441I, HIS441L, ILE135I, ILE135L, ILE147I, ILE147L, ILE151I, ILE151L, ILE177I, ILE177L, ILE194I, ILE194L, ILE201I, ILE201L, ILE203I, ILE203L, ILE206I, ILE206L, ILE221I, ILE221L, ILE224I, ILE224L, ILE231I, ILE231L, ILE446I, ILE446L, LEU113I, LEU113L, LEU118I, LEU118L, LEU124I, LEU124L, LEU127I, LEU127L, LEU143I, LEU143L, LEU145I, LEU145L, LEU178I, LEU178L, LEU181I, LEU181L, LEU186I, LEU186L, LEU199I, LEU199L, LEU202I, LEU202L, LEU225I, LEU225L, LEU363I, LEU363L, LEU408I, LEU408L, LEU437I, LEU437L, LEU438I, LEU438L, LYS10L, LYS136I, LYS136L, LYS137I, LYS137L, LYS188I, LYS188L, LYS189I, LYS189L, LYS192I, LYS192L, LYS19I, LYS19L, LYS209I, LYS209L, LYS216I, LYS216L, LYS223I, LYS223L, LYS228I, LYS228L, LYS22I, LYS22L, LYS248I, LYS248L, LYS357I, LYS357L, LYS365I, LYS365L, LYS410I, LYS410L, LYS449I, LYS449L, MET126I, MET126L, MET258I, MET258L, MET260I, MET260L, MET355I, MET355L, PHE172I, PHE172L, PHE236I, PHE236L, PHE254I, PHE254L, PHE25I, PHE25L, PHE347I, PHE347L, PHE34I, PHE34L, PRO109I, PRO109L, PRO144I, PRO144L, PRO170I, PRO170L, PRO207I, PRO207L, PRO245I, PRO245L, PRO349I, PRO349L, PRO352I, PRO352L, PRO443I, PRO443L, SER175I, SER175L, SER183I, SER183L, SER191I, SER191L, SER205I, SER205L, SER257I, SER257L, SER344I, SER344L, SER447I, SER447L, SER448I, SER448L, THR122I, THR122L, THR142I, THR142L, TRP13I, TRP13L, TRP140I, TRP140L, TRP444I, TRP444L, TYR119I, TYR119L, TYR138I, TYR138L, TYR16I, TYR16L, TYR229I, TYR229L, TYR252I, TYR252L, TYR262I, TYR262L, TYR351I, TYR351L, TYR362I, TYR362L, VAL141I, VAL141L, VAL161I, VAL161L, VAL163I, VAL163L, VAL171I, VAL171L, VAL174I, VAL174L, VAL179I, VAL179L, VAL193I, VAL193L, VAL217I, VAL217L, VAL259I, VAL259L, VAL343I, VAL343L, VAL354I, VAL354L, VAL411I, VAL411L
• I-P: GLU72P, LYS398I, LYS92P
• J-K: ALA190J, ALA239J, ALA302J, ALA315J, ALA332K, ALA384K, ALA390K, ALA406K, ALA420K, ALA424K, ARG110J, ARG330J, ARG330K, ARG358K, ARG376K, ARG393K, ARG394K, ARG42J, ARG81J, ASN116J, ASN312J, ASN335K, ASN359K, ASN370K, ASN382K, ASN385K, ASN79J, ASN80J, ASP112J, ASP121J, ASP155J, ASP198J, ASP235J, ASP293J, ASP316J, ASP383K, ASP412K, CYS381K, GLN115J, GLN215J, GLN306J, GLN404K, GLN413K, GLN429K, GLU120J, GLU128J, GLU195J, GLU197J, GLU233J, GLU234J, GLU240J, GLU242J, GLU295J, GLU296J, GLU311J, GLU326J, GLU326K, GLU356K, GLU387K, GLU391K, GLU407K, GLU425J, GLU425K, GLU8K, GLY133J, GLY134J, GLY156J, GLY196J, GLY298J, GLY301J, GLY304J, GLY374K, GLY377K, GLY380K, GLY409K, GLY414K, GLY417K, GLY427K, GLY82J, HIS130J, ILE135J, ILE151J, ILE158J, ILE194J, ILE231J, ILE300J, ILE389K, ILE395K, ILE422J, ILE422K, ILE431K, ILE60J, ILE63J, LEU111J, LEU113J, LEU118J, LEU127J, LEU241J, LEU327J, LEU327K, LEU329K, LEU333J, LEU333K, LEU392K, LEU396K, LEU408K, LEU423K, LEU5K, LEU6K, LYS114J, LYS136J, LYS137J, LYS153J, LYS154J, LYS188J, LYS218J, LYS294J, LYS308J, LYS328J, LYS328K, LYS331K, LYS357K, LYS371K, LYS378K, LYS398K, LYS410K, LYS7K, LYS83J, MET126J, MET305J, MET318J, MET355K, MET428K, PHE236J, PHE309J, PHE310J, PHE310K, PHE369K, PRO117J, PRO386K, SER191J, SER232J, SER238J, SER299J, SER307J, SER360K, SER375K, SER379K, SER397K, THR129J, THR157J, THR303J, THR313J, THR373K, THR405K, THR418K, TRP403K, TYR119J, TYR131J, TYR132J, TYR138J, TYR334K, TYR362K, TYR372K, TYR388K, TYR421K, TYR426J, TYR426K, TYR9K, VAL150J, VAL152J, VAL193J, VAL237J, VAL297J, VAL314J, VAL411K, VAL430K
• J-L: ALA190L, ALA239L, ALA302L, ALA315L, ALA332J, ALA384J, ALA390J, ALA406J, ALA420J, ALA424J, ARG110L, ARG330J, ARG330L, ARG358J, ARG376J, ARG393J, ARG394J, ARG42L, ARG81L, ASN116L, ASN220L, ASN226L, ASN312L, ASN335J, ASN359J, ASN370J, ASN382J, ASN385J, ASN59L, ASN79L, ASN80L, ASP112L, ASP121L, ASP155L, ASP198L, ASP235L, ASP293L, ASP316L, ASP383J, ASP412J, CYS381J, GLN115L, GLN215L, GLN306L, GLN404J, GLN413J, GLN429J, GLU120L, GLU128L, GLU195L, GLU197L, GLU213L, GLU233L, GLU234L, GLU240L, GLU242L, GLU295L, GLU296L, GLU311L, GLU326J, GLU326L, GLU356J, GLU387J, GLU391J, GLU407J, GLU425J, GLU8J, GLY133L, GLY134L, GLY156L, GLY196L, GLY298L, GLY301L, GLY304L, GLY374J, GLY377J, GLY380J, GLY409J, GLY414J, GLY417J, GLY427J, GLY82L, HIS130L, HIS219L, ILE135L, ILE151L, ILE158L, ILE194L, ILE221L, ILE231L, ILE300L, ILE317L, ILE389J, ILE395J, ILE422J, ILE422L, ILE431J, ILE60L, ILE63L, LEU111L, LEU113L, LEU118L, LEU127L, LEU208L, LEU241L, LEU327J, LEU327L, LEU329J, LEU333J, LEU333L, LEU392J, LEU396J, LEU408J, LEU423J, LEU5J, LEU6J, LYS114L, LYS136L, LYS137L, LYS153L, LYS154L, LYS188L, LYS216L, LYS218L, LYS223L, LYS294L, LYS308L, LYS328J, LYS328L, LYS331J, LYS357J, LYS371J, LYS378J, LYS398J, LYS410J, LYS7J, LYS83L, MET126L, MET222L, MET305L, MET318L, MET355J, MET428J, PHE236L, PHE309L, PHE310J, PHE310L, PHE369J, PRO109L, PRO117L, PRO386J, SER191L, SER232L, SER238L, SER299L, SER307L, SER360J, SER375J, SER379J, SER397J, THR129L, THR157L, THR303L, THR313L, THR373J, THR405J, THR418J, TRP403J, TYR119L, TYR131L, TYR132L, TYR138L, TYR334J, TYR362J, TYR372J, TYR388J, TYR421J, TYR426J, TYR426L, TYR9J, VAL150L, VAL152L, VAL193L, VAL237L, VAL297L, VAL314L, VAL411J, VAL430J
• K-L: ALA190K, ALA239K, ALA302K, ALA315K, ALA332L, ALA384L, ALA390L, ALA406L, ALA420L, ALA424L, ALA78K, ARG110K, ARG330K, ARG330L, ARG358L, ARG376L, ARG393L, ARG394L, ARG42K, ARG81K, ASN116K, ASN220K, ASN226K, ASN312K, ASN335L, ASN359L, ASN370L, ASN382L, ASN385L, ASN59K, ASN79K, ASN80K, ASP112K, ASP121K, ASP155K, ASP198K, ASP235K, ASP293K, ASP316K, ASP383L, ASP412L, CYS381L, GLN115K, GLN215K, GLN306K, GLN404L, GLN413L, GLN429L, GLU120K, GLU128K, GLU195K, GLU197K, GLU213K, GLU233K, GLU234K, GLU240K, GLU242K, GLU295K, GLU296K, GLU311K, GLU326K, GLU326L, GLU356L, GLU387L, GLU391L, GLU407L, GLU425K, GLU425L, GLU8L, GLY133K, GLY134K, GLY156K, GLY196K, GLY298K, GLY301K, GLY304K, GLY374L, GLY377L, GLY380L, GLY409L, GLY414L, GLY417L, GLY427L, GLY82K, HIS130K, HIS219K, ILE135K, ILE151K, ILE158K, ILE194K, ILE221K, ILE231K, ILE300K, ILE317K, ILE389L, ILE395L, ILE422K, ILE422L, ILE431L, ILE60K, ILE63K, LEU111K, LEU113K, LEU118K, LEU127K, LEU208K, LEU241K, LEU327K, LEU327L, LEU329L, LEU333K, LEU333L, LEU392L, LEU396L, LEU408L, LEU423L, LEU5L, LEU6L, LYS114K, LYS136K, LYS137K, LYS153K, LYS154K, LYS188K, LYS218K, LYS223K, LYS294K, LYS308K, LYS328K, LYS328L, LYS331L, LYS357L, LYS371L, LYS378L, LYS398L, LYS410L, LYS7L, LYS83K, MET126K, MET222K, MET305K, MET318K, MET355L, MET428L, PHE236K, PHE309K, PHE310K, PHE310L, PHE369L, PRO117K, PRO386L, SER191K, SER232K, SER238K, SER299K, SER307K, SER360L, SER375L, SER379L, SER397L, THR129K, THR157K, THR303K, THR313K, THR373L, THR405L, THR418L, TRP403L, TYR119K, TYR131K, TYR132K, TYR138K, TYR334L, TYR362L, TYR372L, TYR388L, TYR421L, TYR426K, TYR426L, TYR9L, VAL150K, VAL152K, VAL193K, VAL237K, VAL297K, VAL314K, VAL411L, VAL430L
• L-O: ASP62O, GLU61O, LYS209L
• M-P: ARG250M, ARG250P, ARG256M, ARG256P, ASN200M, ASN200P, ASN350M, ASP121P, ASP123M, ASP123P, ASP14M, ASP14P, ASP166P, ASP167M, ASP167P, ASP169M, ASP169P, ASP176M, ASP176P, ASP17M, ASP17P, ASP210M, ASP210P, ASP251M, ASP251P, ASP255M, ASP255P, ASP348M, ASP348P, GLN185M, GLN185P, GLU187M, GLU187P, GLY164M, GLY164P, GLY173M, GLY253M, GLY253P, HIS180M, HIS180P, HIS441M, HIS441P, ILE177M, ILE177P, ILE201M, ILE201P, LEU186M, LEU186P, LYS136M, LYS136P, LYS137M, LYS137P, LYS188M, LYS188P, LYS189M, LYS189P, LYS192M, LYS192P, LYS216P, LYS223M, LYS223P, LYS248M, LYS248P, LYS365M, LYS365P, PHE254M, PHE254P, SER175M, SER175P, TYR252M, TYR252P, VAL171M, VAL171P
• M-Q: ALA302M, ALA424Q, ARG330Q, ARG358Q, ARG376Q, ARG393Q, ARG394Q, ARG81M, ASN116M, ASN359Q, ASP112M, ASP155M, ASP235M, ASP293M, ASP383Q, ASP412Q, GLN115M, GLU128M, GLU195M, GLU197M, GLU233M, GLU234M, GLU240M, GLU311M, GLU356Q, GLU387Q, GLU391Q, GLU407Q, GLU425Q, GLU8Q, GLY380Q, HIS130M, LEU5Q, LYS114M, LYS136M, LYS153M, LYS154M, LYS294M, LYS328M, LYS328Q, LYS331Q, LYS371Q, LYS378Q, LYS410Q, LYS7Q, LYS83M, SER307M, THR405Q, TYR138M, VAL297M
• M-U: ALA302U, ALA424M, ARG330M, ARG358M, ARG376M, ARG393M, ARG394M, ARG81U, ASN116U, ASN359M, ASP112U, ASP155U, ASP235U, ASP293U, ASP383M, ASP412M, GLN115U, GLU128U, GLU195U, GLU197U, GLU233U, GLU234U, GLU240U, GLU311U, GLU356M, GLU387M, GLU391M, GLU407M, GLU425M, GLU8M, GLY380M, HIS130U, LYS114U, LYS136U, LYS153U, LYS154U, LYS294U, LYS328M, LYS328U, LYS331M, LYS371M, LYS378M, LYS410M, LYS7M, LYS83U, SER238U, SER307U, VAL297U
• N-O: ARG330O, ARG358O, ARG376O, ARG393O, ARG394O, ARG81N, ASN116N, ASN220N, ASN226N, ASN359O, ASP112N, ASP155N, ASP230N, ASP235N, ASP293N, ASP383O, ASP412O, GLN115N, GLN215N, GLU120N, GLU128N, GLU195N, GLU197N, GLU213N, GLU233N, GLU234N, GLU240N, GLU311N, GLU356O, GLU387O, GLU391O, GLU407O, GLU425O, GLU8O, GLY133N, GLY377O, GLY380O, HIS130N, HIS219N, ILE221N, ILE231N, LEU118N, LEU208N, LEU5O, LEU6O, LYS114N, LYS136N, LYS153N, LYS154N, LYS216N, LYS218N, LYS223N, LYS294N, LYS328N, LYS328O, LYS331O, LYS371O, LYS378O, LYS410O, LYS7O, LYS83N, MET222N, PHE236N, PRO117N, SER232N, SER307N, SER397O, THR405O, TYR119N, TYR138N, TYR9O, VAL217N, VAL237N, VAL297N
• N-P: ALA302P, ALA424N, ARG330N, ARG358N, ARG376N, ARG393N, ARG394N, ARG81P, ASN116P, ASN359N, ASP112P, ASP155P, ASP235P, ASP293P, ASP383N, ASP412N, GLN115P, GLU128P, GLU195P, GLU197P, GLU233P, GLU234P, GLU240P, GLU311P, GLU356N, GLU387N, GLU391N, GLU407N, GLU425N, GLU8N, GLY380N, HIS130P, LYS114P, LYS136P, LYS153P, LYS154P, LYS294P, LYS328N, LYS328P, LYS331N, LYS371N, LYS378N, LYS410N, LYS7N, LYS83P, SER238P, SER307P, THR405N, TYR138P, VAL297P
• N-W: ARG250N, ARG250W, ARG256N, ARG256W, ASN200N, ASP123N, ASP123W, ASP14N, ASP14W, ASP166N, ASP167N, ASP167W, ASP169N, ASP169W, ASP176N, ASP176W, ASP17N, ASP17W, ASP210N, ASP210W, ASP251N, ASP251W, ASP255N, ASP255W, ASP348N, ASP348W, GLN185N, GLN185W, GLU187N, GLU187W, GLY164N, GLY164W, GLY173N, GLY253N, GLY253W, HIS180N, HIS180W, HIS441N, HIS441W, ILE177N, ILE177W, ILE201N, ILE201W, LEU186N, LEU186W, LYS136N, LYS136W, LYS137N, LYS137W, LYS188N, LYS188W, LYS189N, LYS189W, LYS192N, LYS192W, LYS216N, LYS216W, LYS223N, LYS223W, LYS248N, LYS248W, LYS365N, LYS365W, PHE254N, PHE254W, TYR252W, VAL171N, VAL171W
• O-P: ALA302O, ALA424P, ARG330P, ARG358P, ARG376P, ARG393P, ARG394P, ARG81O, ASN116O, ASN359P, ASP112O, ASP155O, ASP235O, ASP293O, ASP383P, ASP412P, GLN115O, GLU128O, GLU195O, GLU197O, GLU233O, GLU234O, GLU240O, GLU311O, GLU356P, GLU387P, GLU391P, GLU407P, GLU425P, GLU8P, GLY380P, HIS130O, LEU5P, LYS114O, LYS136O, LYS153O, LYS154O, LYS294O, LYS328O, LYS328P, LYS331P, LYS371P, LYS378P, LYS410P, LYS7P, LYS83O, SER307O, THR405P, TYR138O, VAL297O
• O-R: ARG250O, ARG250R, ARG256O, ARG256R, ASN200O, ASN200R, ASN350O, ASP121O, ASP121R, ASP123O, ASP123R, ASP14O, ASP14R, ASP166O, ASP166R, ASP167O, ASP167R, ASP169O, ASP169R, ASP176O, ASP176R, ASP17O, ASP17R, ASP198O, ASP210O, ASP210R, ASP251O, ASP251R, ASP255O, ASP255R, ASP348O, ASP348R, GLN185O, GLN185R, GLU187O, GLU187R, GLY164O, GLY164R, GLY173O, GLY253O, GLY253R, HIS180O, HIS180R, HIS441O, HIS441R, ILE177O, ILE177R, ILE201O, ILE201R, LEU186O, LEU186R, LYS136O, LYS136R, LYS137O, LYS137R, LYS188O, LYS188R, LYS189O, LYS189R, LYS192O, LYS192R, LYS216O, LYS216R, LYS223O, LYS223R, LYS248O, LYS248R, LYS365O, LYS365R, PHE254O, PHE254R, SER175O, SER175R, TYR252O, TYR252R, VAL171O, VAL171R
• Q-T: ARG250Q, ARG250T, ARG256Q, ARG256T, ASN200T, ASN350Q, ASP121Q, ASP121T, ASP123Q, ASP123T, ASP14Q, ASP14T, ASP166Q, ASP167Q, ASP167T, ASP169Q, ASP169T, ASP176Q, ASP176T, ASP17Q, ASP17T, ASP210Q, ASP210T, ASP251Q, ASP251T, ASP255Q, ASP255T, ASP348Q, ASP348T, GLN185Q, GLN185T, GLU187Q, GLU187T, GLY164Q, GLY164T, GLY173Q, GLY253Q, GLY253T, HIS180Q, HIS180T, HIS441Q, HIS441T, ILE177Q, ILE177T, ILE201Q, ILE201T, LEU186Q, LEU186T, LYS136Q, LYS136T, LYS137Q, LYS137T, LYS188Q, LYS188T, LYS189Q, LYS189T, LYS192Q, LYS192T, LYS216Q, LYS216T, LYS223Q, LYS223T, LYS248Q, LYS248T, LYS365Q, LYS365T, PHE254Q, PHE254T, SER175T, TYR252Q, TYR252T, VAL171Q, VAL171T
• Q-U: ARG330U, ARG358U, ARG376U, ARG393U, ARG394U, ARG81Q, ASN116Q, ASN359U, ASP112Q, ASP155Q, ASP235Q, ASP293Q, ASP383U, ASP412U, GLN115Q, GLU128Q, GLU195Q, GLU197Q, GLU233Q, GLU234Q, GLU240Q, GLU311Q, GLU356U, GLU387U, GLU391U, GLU407U, GLU425U, GLU8U, GLY380U, HIS130Q, LEU5U, LYS114Q, LYS136Q, LYS153Q, LYS154Q, LYS294Q, LYS328Q, LYS328U, LYS331U, LYS371U, LYS378U, LYS410U, LYS7U, LYS83Q, SER307Q, TYR9U, VAL297Q
• R-S: ALA302R, ALA424S, ARG330S, ARG358S, ARG376S, ARG393S, ARG394S, ARG81R, ASN116R, ASN359S, ASP112R, ASP155R, ASP235R, ASP293R, ASP383S, ASP412S, GLN115R, GLN215R, GLU128R, GLU195R, GLU197R, GLU233R, GLU234R, GLU240R, GLU311R, GLU356S, GLU387S, GLU391S, GLU407S, GLU425S, GLU8S, GLY133R, GLY377S, GLY380S, HIS130R, LEU5S, LYS114R, LYS136R, LYS153R, LYS154R, LYS294R, LYS328R, LYS328S, LYS331S, LYS371S, LYS378S, LYS410S, LYS7S, LYS83R, SER307R, SER397S, THR405S, TYR138R, VAL297R
• R-T: ALA302T, ALA424R, ARG330R, ARG358R, ARG376R, ARG393R, ARG394R, ARG81T, ASN116T, ASN359R, ASP112T, ASP155T, ASP235T, ASP293T, ASP383R, ASP412R, GLN115T, GLU128T, GLU195T, GLU197T, GLU233T, GLU234T, GLU240T, GLU311T, GLU356R, GLU387R, GLU391R, GLU407R, GLU425R, GLU8R, GLY133T, GLY377R, GLY380R, HIS130T, LEU5R, LYS114T, LYS136T, LYS153T, LYS154T, LYS294T, LYS328R, LYS328T, LYS331R, LYS371R, LYS378R, LYS410R, LYS7R, LYS83T, SER238T, SER307T, TYR131T, VAL297T
• S-T: ALA302S, ALA424T, ARG330T, ARG358T, ARG376T, ARG393T, ARG394T, ARG81S, ASN116S, ASN359T, ASP112S, ASP155S, ASP235S, ASP293S, ASP383T, ASP412T, GLN115S, GLU128S, GLU195S, GLU197S, GLU233S, GLU234S, GLU240S, GLU311S, GLU356T, GLU387T, GLU391T, GLU407T, GLU425T, GLU8T, GLY380T, HIS130S, LYS114S, LYS136S, LYS153S, LYS154S, LYS294S, LYS328S, LYS328T, LYS331T, LYS371T, LYS378T, LYS410T, LYS7T, LYS83S, SER307S, TYR9T, VAL297S
• S-V: ARG250S, ARG250V, ARG256S, ARG256V, ASN350S, ASP123S, ASP123V, ASP14S, ASP14V, ASP166S, ASP167S, ASP167V, ASP169S, ASP169V, ASP176S, ASP176V, ASP17S, ASP17V, ASP210S, ASP210V, ASP251S, ASP251V, ASP255S, ASP255V, ASP348S, ASP348V, GLN185S, GLN185V, GLU187S, GLU187V, GLY164S, GLY164V, GLY173S, GLY253S, GLY253V, HIS180S, HIS180V, HIS441S, HIS441V, ILE177S, ILE177V, ILE201S, ILE201V, LEU186S, LEU186V, LYS136S, LYS136V, LYS137S, LYS137V, LYS188S, LYS188V, LYS189S, LYS189V, LYS192S, LYS192V, LYS216S, LYS216V, LYS223S, LYS223V, LYS248S, LYS248V, LYS365S, LYS365V, PHE254S, PHE254V, SER175V, TYR252V, VAL171S, VAL171V
• U-X: ARG250U, ARG250X, ARG256U, ARG256X, ASP123U, ASP123X, ASP14U, ASP14X, ASP166X, ASP167U, ASP167X, ASP169U, ASP169X, ASP176U, ASP176X, ASP17U, ASP17X, ASP210U, ASP210X, ASP251U, ASP251X, ASP255U, ASP255X, ASP348U, ASP348X, GLN185U, GLN185X, GLU187U, GLU187X, GLY164U, GLY164X, GLY173U, GLY253U, GLY253X, HIS180U, HIS180X, HIS441U, HIS441X, ILE177U, ILE177X, ILE201U, ILE201X, LEU186U, LEU186X, LYS136U, LYS136X, LYS137U, LYS137X, LYS188U, LYS188X, LYS189U, LYS189X, LYS192U, LYS192X, LYS216U, LYS216X, LYS223U, LYS223X, LYS248U, LYS248X, LYS365U, LYS365X, PHE254U, PHE254X, TYR252X, VAL171U, VAL171X
• V-W: ALA302V, ALA424W, ARG330W, ARG358W, ARG376W, ARG393W, ARG394W, ARG81V, ASN116V, ASN359W, ASP112V, ASP155V, ASP235V, ASP293V, ASP383W, ASP412W, GLN115V, GLU128V, GLU195V, GLU197V, GLU233V, GLU234V, GLU240V, GLU311V, GLU356W, GLU387W, GLU391W, GLU407W, GLU425W, GLU8W, GLY133V, GLY377W, GLY380W, HIS130V, LEU5W, LYS114V, LYS136V, LYS153V, LYS154V, LYS294V, LYS328V, LYS328W, LYS331W, LYS371W, LYS378W, LYS410W, LYS7W, LYS83V, SER307V, SER397W, TYR9W, VAL297V
• V-X: ALA302X, ALA424V, ARG330V, ARG358V, ARG376V, ARG393V, ARG394V, ARG81X, ASN116X, ASN359V, ASP112X, ASP155X, ASP235X, ASP293X, ASP383V, ASP412V, GLN115X, GLU128X, GLU195X, GLU197X, GLU233X, GLU234X, GLU240X, GLU311X, GLU356V, GLU387V, GLU391V, GLU407V, GLU425V, GLU8V, GLY380V, HIS130X, LEU5V, LYS114X, LYS136X, LYS153X, LYS154X, LYS294X, LYS328V, LYS328X, LYS331V, LYS371V, LYS378V, LYS410V, LYS7V, LYS83X, SER238X, SER307X, VAL297X
• W-X: ARG330X, ARG358X, ARG376X, ARG393X, ARG394X, ARG81W, ASN116W, ASN359X, ASP112W, ASP155W, ASP235W, ASP293W, ASP383X, ASP412X, GLN115W, GLU128W, GLU195W, GLU197W, GLU233W, GLU234W, GLU240W, GLU311W, GLU356X, GLU387X, GLU391X, GLU407X, GLU425X, GLU8X, GLY380X, HIS130W, LYS114W, LYS136W, LYS153W, LYS154W, LYS294W, LYS328W, LYS328X, LYS331X, LYS371X, LYS378X, LYS410X, LYS7X, LYS83W, SER307W, SER397X, VAL297W