2GC7

substrate reduced, copper free complex of methylamine dehydrogenase, amicyanin and cytochrome c551i from paracoccus denitrificans.

• Total interactions analyzed: 120
• Total true interactions: 31
• Strongest Interaction:
  • Chains: I-J
  • Int. Res.: 147
  • Norm. En. per Res.: -4.9049
• Hub Node: A(6)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-134.7499	-84.8033	-494.218	-713.7713	147	22	11	18498	13	57	46
A-C	-12.4786	-40.0835	-61.7261	-114.2882	32	1	0	2488	4	11	7
A-D	0.0	0.0	-0.0618	-0.0618	4	0	0	7	0	1	4
A-E	-34.9465	-87.4724	-145.377	-267.7958	82	3	7	6372	10	30	22
A-F	-102.7173	-25.6258	-404.324	-532.6671	137	19	7	16004	4	30	22
A-G	0.0	-6.6709	-2.1698	-8.8407	6	0	0	195	0	5	1
B-C	0.0	-7.7729	-94.7538	-102.5267	58	2	3	5015	1	15	12
B-D	0.0	0.0	-0.0006	-0.0006	2	0	0	2	0	0	0
B-E	-105.7338	-20.915	-404.708	-531.3568	137	21	6	16045	4	30	23
C-D	-20.161	24.8721	-117.094	-112.3829	53	6	2	4352	0	19	16
C-E	0.0	-18.5984	-5.5149	-24.1134	8	0	0	309	0	6	3
E-F	-127.2649	-93.0923	-493.803	-714.1602	147	25	11	18540	13	57	46
E-G	-12.2488	-42.4978	-64.4512	-119.1978	33	1	0	2487	4	10	8
E-H	0.0	0.0	-0.1183	-0.1183	5	0	0	22	0	1	4
F-G	0.0	-9.3024	-99.1171	-108.4195	61	3	2	4972	1	15	13
G-H	-28.5329	16.6428	-119.13	-131.0201	57	6	1	4511	1	20	16
I-J	-133.1919	-87.3353	-500.498	-721.0252	147	23	11	18590	13	57	48
I-K	-14.6213	-43.7757	-61.83	-120.2269	33	2	0	2457	4	10	8
I-L	0.0	0.0	-0.0424	-0.0424	2	0	0	18	0	1	4
I-M	-37.0958	-87.2366	-145.509	-269.8414	84	3	7	6317	10	30	24
I-N	-103.5072	-20.7084	-402.3	-526.5156	135	20	6	15813	4	30	24
I-O	0.0	-10.5659	-3.7955	-14.3614	7	0	0	242	0	6	1
J-K	0.0	-9.2419	-98.2463	-107.4882	61	3	2	5020	1	15	14
J-M	-102.7628	-20.2213	-407.349	-530.3331	135	27	7	16061	4	30	24
K-L	-36.3155	11.1251	-118.137	-143.3275	57	5	1	4485	3	19	16
K-M	0.0	-7.0058	-2.0756	-9.0814	6	0	0	179	0	6	2
M-N	-131.9122	-81.9562	-485.989	-699.8573	146	22	11	18515	13	57	47
M-O	-9.5592	-43.749	-64.4749	-117.7831	32	2	0	2537	4	10	8
M-P	0.0	0.0	-0.3972	-0.3972	7	0	0	71	0	2	5
N-O	0.0	-9.4403	-99.7609	-109.2012	59	2	3	4933	1	15	13
O-P	-22.8358	18.3595	-117.227	-121.7033	51	6	1	4387	1	20	17

Interface residues

• A-B: ALA103A, ALA103B, ALA116B, ALA11B, ALA130A, ALA309A, ALA53A, ALA55B, ALA56A, ALA57A, ARG101A, ARG104A, ARG107A, ARG10B, ARG132A, ARG197A, ARG278A, ARG301A, ARG305A, ARG311A, ARG99B, ASN104B, ASN229A, ASN34B, ASN81B, ASN90B, ASP105B, ASP114B, ASP115B, ASP180A, ASP198A, ASP224A, ASP24B, ASP299A, ASP302A, ASP32B, ASP334A, ASP8B, CYS109B, CYS121B, CYS181A, CYS196A, CYS23B, CYS29B, CYS78B, CYS88B, GLN155A, GLN300A, GLN378A, GLU101B, GLU106A, GLU223A, GLU225A, GLU303A, GLU332A, GLU92B, GLU94B, GLY105A, GLY111B, GLY136A, GLY199A, GLY276A, GLY280A, GLY281A, GLY33B, GLY49B, GLY79B, GLY84B, GLY93B, HIS120B, HIS183A, HIS195A, HIS221A, HIS230A, HIS28B, HIS306A, HIS331A, HIS375A, HIS54A, ILE102A, ILE106B, ILE107B, ILE228A, ILE31B, ILE333A, LEU134A, LEU227A, LEU80A, LEU89B, LEU95B, LYS12B, LYS307A, LYS51B, MET117B, MET141A, PHE102B, PHE110B, PHE133A, PHE156A, PHE226A, PHE312A, PHE55A, PHE79A, PHE99A, PRO100B, PRO158A, PRO160A, PRO222A, PRO231A, PRO52A, PRO87B, PRO96B, PRO9B, SER157A, SER30B, SER310A, SER83B, THR118B, THR122B, THR137A, THR244A, THR308A, THR351A, THR50B, THR7B, THR91B, THR97A, TRP108B, TRP13B, TRP242A, TRP277A, TRP282A, TRP304A, TYR119B, TYR138A, TYR154A, TYR182A, TYR245A, TYR80B, TYR98B, VAL135A, VAL14B, VAL298A, VAL58A, VAL82B, VAL97B, VAL98A
• A-C: ALA159A, ALA59C, ALA66C, ARG197A, ARG99C, ASP180A, CYS181A, CYS92C, GLN155A, HIS53C, HIS56C, HIS91C, HIS95C, LYS68C, MET28C, MET51C, MET98C, PHE133A, PHE156A, PHE57C, PHE97C, PRO158A, PRO160A, PRO179A, PRO94C, PRO96C, SER157A, THR93C, TYR154A, TYR182A, VAL178A, VAL58C
• A-D: GLN146D, GLU223A, PRO144D, VAL219A
• A-E: ALA103A, ALA103E, ALA123A, ALA123E, ALA53A, ALA53E, ALA56A, ALA56E, ALA57A, ALA57E, ARG101A, ARG101E, ARG104A, ARG104E, ASP109A, ASP109E, ASP124A, ASP124E, ASP76A, ASP76E, GLN60A, GLN60E, GLU112A, GLU112E, GLU126A, GLU126E, GLU5A, GLY352E, GLY77A, GLY77E, GLY78A, GLY78E, HIS375A, HIS375E, HIS54A, HIS54E, HIS94A, HIS94E, ILE102A, ILE102E, ILE125A, ILE125E, ILE75A, ILE75E, LEU119A, LEU119E, LEU120A, LEU120E, LEU127A, LEU127E, LYS354A, LYS354E, PHE114A, PHE114E, PHE79A, PHE79E, PHE99A, PHE99E, PRO121A, PRO121E, PRO81A, PRO81E, SER100A, SER100E, SER96A, SER96E, THR108A, THR108E, THR59A, THR59E, THR97A, THR97E, TYR110A, TYR110E, VAL111A, VAL111E, VAL113A, VAL113E, VAL58A, VAL58E, VAL98A, VAL98E
• A-F: ALA10A, ALA112F, ALA17A, ALA18A, ALA19A, ALA21A, ALA22A, ALA22F, ALA23A, ALA24A, ALA27A, ALA39A, ALA53F, ALA6A, ALA73F, ARG20A, ARG27F, ARG35A, ARG46A, ARG70A, ARG75F, ARG85F, ASN18F, ASN34F, ASN371A, ASN45F, ASN63F, ASN81F, ASP114F, ASP115A, ASP17F, ASP19F, ASP24F, ASP25A, ASP31A, ASP32A, ASP37F, ASP66F, ASP76A, CB8.76766-4.36777, CYS23F, CYS36F, CYS38F, CYS46F, CYS77F, CYS78F, CYS86F, CYS88F, GLN11A, GLN14A, GLN16A, GLN16F, GLN21F, GLN30A, GLN372A, GLN60A, GLN61A, GLN68F, GLU113F, GLU12A, GLU33A, GLU38A, GLU5A, GLU5A5, GLU7A, GLY128F, GLY15A, GLY374A, GLY40F, GLY41F, GLY49F, GLY69A, GLY73A, GLY77A, GLY79F, GLY84F, HIS120F, HIS375A, ILE123F, ILE126F, ILE20F, ILE35F, ILE36A, ILE64A, ILE72A, ILE72F, ILE75A, ILE92A, LEU119A, LEU120A, LEU26A, LEU356A, LEU373A, LEU37A, LEU43F, LEU52F, LYS129F, LYS354A, LYS51F, MET74A, PHE114A, PHE62A, PRO116A, PRO121A, PRO125F, PRO34A, PRO40A, PRO47F, PRO48F, PRO87F, SER124F, SER369A, SER39F, SER42F, SER83F, THR118A, THR118F, THR13A, THR355A, THR44F, THR50F, THR54F, THR59A, THR65F, THR8A, TRP26F, TYR119F, TYR25F, TYR70F, TYR80F, VAL117A, VAL127F, VAL370A, VAL58A, VAL63A, VAL71A, VAL82F
• A-G: ASP31A, ASP32A, GLN76G, GLU33A, LYS73G, PRO34A
• B-C: ALA103B, ALA112B, ALA130B, ALA50C, ALA53B, ALA55B, ALA59B, ALA73B, ARG75B, ARG99B, ASN47C, ASN54C, ASP114B, ASP115B, CYS109B, CYS92C, GLU101B, GLU113B, GLU49C, GLY111B, GLY128B, GLY69C, HIS53C, HIS56C, HIS95C, ILE106B, ILE126B, ILE72B, LEU71B, LYS129B, LYS68C, LYS73C, LYS74C, MET28C, MET51C, MET71C, MET72C, MET98C, PHE102B, PHE110B, PHE97C, PRO100B, PRO125B, PRO52C, PRO70C, PRO94C, PRO96C, SER131B, SER56B, THR54B, THR93C, TRP108B, TYR70B, TYR74B, TYR98B, VAL127B, VAL58B, VAL97B
• B-D: LYS129D, SER131B
• B-E: ALA10E, ALA112B, ALA17E, ALA18E, ALA19E, ALA21E, ALA22B, ALA22E, ALA23E, ALA24E, ALA27E, ALA39E, ALA53B, ALA6E, ALA73B, ARG20E, ARG27B, ARG35E, ARG46E, ARG70E, ARG75B, ARG85B, ASN18B, ASN34B, ASN371E, ASN45B, ASN63B, ASN81B, ASP114B, ASP115E, ASP17B, ASP19B, ASP24B, ASP25E, ASP31E, ASP32E, ASP37B, ASP66B, ASP76E, CYS23B, CYS36B, CYS38B, CYS46B, CYS77B, CYS78B, CYS86B, CYS88B, GLN11E, GLN14E, GLN16B, GLN16E, GLN21B, GLN30E, GLN372E, GLN60E, GLN61E, GLN68B, GLU113B, GLU12E, GLU33E, GLU38E, GLU5E, GLU7E, GLY128B, GLY15E, GLY29E, GLY374E, GLY40B, GLY41B, GLY49B, GLY69E, GLY73E, GLY77E, GLY79B, GLY84B, HIS120B, HIS375E, ILE123B, ILE126B, ILE20B, ILE35B, ILE36E, ILE64E, ILE72B, ILE72E, ILE75E, ILE92E, LEU119E, LEU120E, LEU26E, LEU356E, LEU373E, LEU37E, LEU43B, LEU52B, LEU89B, LYS129B, LYS354E, LYS51B, MET74E, PHE114E, PHE62E, PRO116E, PRO121E, PRO125B, PRO34E, PRO40E, PRO47B, PRO48B, PRO87B, SER124B, SER369E, SER39B, SER42B, SER83B, THR118B, THR118E, THR13E, THR355E, THR44B, THR50B, THR54B, THR59E, THR65B, THR8E, TRP26B, TYR119B, TYR25B, TYR70B, TYR80B, VAL117E, VAL127B, VAL370E, VAL58E, VAL63E, VAL71E, VAL82B
• C-D: ALA26C, ALA65D, ALA76D, ARG48C, ASN47C, ASN74D, ASP127D, ASP130D, ASP18C, ASP24C, ASP75D, CYS60D, GLN100D, GLU31C, GLU34C, GLU49C, GLU66D, GLU75C, GLY126D, GLY19C, GLY62D, GLY67D, GLY70D, GLY72D, GLY99D, HIS36C, HIS61D, ILE25C, ILE46C, ILE69D, ILE8D, LEU35C, LEU73D, LYS101C, LYS27C, LYS29C, LYS68D, LYS74C, MET28C, PRO33C, PRO71D, THR125D, THR32C, THR79D, THR98D, TRP78D, TYR124D, TYR30C, TYR77D, TYR80D, VAL103C, VAL22C, VAL23C
• C-E: ASP31E, ASP32E, GLN30E, GLN76C, GLU33E, LYS73C, PRO10C, PRO34E
• E-F: ALA103E, ALA103F, ALA116F, ALA11F, ALA130E, ALA309E, ALA53E, ALA55F, ALA56E, ALA57E, ARG101E, ARG104E, ARG107E, ARG10F, ARG132E, ARG197E, ARG278E, ARG301E, ARG305E, ARG311E, ARG99F, ASN104F, ASN229E, ASN34F, ASN81F, ASN90F, ASP105F, ASP114F, ASP115F, ASP180E, ASP198E, ASP224E, ASP24F, ASP299E, ASP302E, ASP32F, ASP334E, ASP8F, CYS109F, CYS121F, CYS181E, CYS196E, CYS23F, CYS29F, CYS78F, CYS88F, GLN155E, GLN300E, GLN378E, GLU101F, GLU106E, GLU223E, GLU225E, GLU303E, GLU332E, GLU92F, GLU94F, GLY105E, GLY136E, GLY199E, GLY276E, GLY280E, GLY281E, GLY33F, GLY49F, GLY79F, GLY84F, GLY93F, HIS120F, HIS183E, HIS195E, HIS221E, HIS230E, HIS28F, HIS306E, HIS331E, HIS375E, HIS54E, ILE102E, ILE106F, ILE107F, ILE228E, ILE31F, ILE333E, LEU134E, LEU227E, LEU297E, LEU80E, LEU89F, LEU95F, LYS12F, LYS307E, LYS51F, MET117F, MET141E, PHE102F, PHE110F, PHE133E, PHE156E, PHE226E, PHE312E, PHE55E, PHE79E, PHE99E, PRO100F, PRO158E, PRO222E, PRO231E, PRO243E, PRO52E, PRO87F, PRO96F, PRO9F, SER157E, SER30F, SER310E, SER83F, THR118F, THR122F, THR137E, THR244E, THR308E, THR351E, THR50F, THR7F, THR91F, THR97E, TRP108F, TRP13F, TRP242E, TRP277E, TRP282E, TRP304E, TYR119F, TYR138E, TYR154E, TYR182E, TYR245E, TYR80F, TYR98F, VAL135E, VAL14F, VAL298E, VAL58E, VAL82F, VAL97F, VAL98E
• E-G: ALA159E, ALA59G, ALA66G, ARG197E, ARG99G, ASP180E, CYS181E, CYS92G, GLN155E, HIS53G, HIS56G, HIS91G, HIS95G, LYS27G, LYS68G, MET28G, MET51G, MET98G, PHE133E, PHE156E, PHE57G, PHE97G, PRO158E, PRO160E, PRO179E, PRO94G, PRO96G, SER157E, THR93G, TYR154E, TYR182E, VAL178E, VAL58G
• E-H: ASP198E, GLN146H, GLU223E, THR125H, VAL219E
• F-G: ALA103F, ALA112F, ALA116F, ALA130F, ALA50G, ALA53F, ALA55F, ALA59F, ALA66G, ALA73F, ARG75F, ARG99F, ASN47G, ASN54G, ASP114F, ASP115F, CYS109F, CYS92G, GLU101F, GLU113F, GLU49G, GLY111F, GLY128F, GLY69G, HIS53G, HIS56G, HIS91G, HIS95G, ILE106F, ILE126F, ILE72F, LEU71F, LYS129F, LYS68G, LYS73G, LYS74G, MET28G, MET51G, MET71G, MET72G, MET98G, PHE102F, PHE110F, PHE97G, PRO100F, PRO125F, PRO52G, PRO70G, PRO94G, PRO96G, SER131F, SER56F, THR54F, THR93G, TRP108F, TYR70F, TYR74F, TYR98F, VAL127F, VAL58F, VAL97F
• G-H: ALA26G, ALA65H, ALA76H, ARG48G, ASN47G, ASN74H, ASP127H, ASP130H, ASP18G, ASP24G, ASP75H, CYS60H, GLN100H, GLU105G, GLU31G, GLU34G, GLU49G, GLU66H, GLU75G, GLY126H, GLY19G, GLY62H, GLY67H, GLY70H, GLY72H, GLY99H, HIS36G, HIS61H, ILE21G, ILE25G, ILE46G, ILE69H, ILE8H, LEU35G, LEU73H, LYS101G, LYS27G, LYS29G, LYS38G, LYS68H, LYS74G, MET28G, PRO33G, PRO71H, PRO81H, THR125H, THR32G, THR79H, THR98H, TRP78H, TYR124H, TYR30G, TYR77H, TYR80H, VAL103G, VAL22G, VAL23G
• I-J: ALA103I, ALA103J, ALA116J, ALA11J, ALA130I, ALA309I, ALA53I, ALA55J, ALA56I, ALA57I, ARG101I, ARG104I, ARG107I, ARG10J, ARG132I, ARG197I, ARG278I, ARG301I, ARG305I, ARG311I, ARG99J, ASN104J, ASN229I, ASN34J, ASN81J, ASN90J, ASP105J, ASP114J, ASP115J, ASP180I, ASP198I, ASP224I, ASP24J, ASP299I, ASP302I, ASP32J, ASP334I, ASP8J, CYS109J, CYS121J, CYS181I, CYS196I, CYS23J, CYS29J, CYS78J, CYS88J, GLN155I, GLN300I, GLN378I, GLU101J, GLU106I, GLU223I, GLU225I, GLU303I, GLU332I, GLU92J, GLU94J, GLY105I, GLY111J, GLY136I, GLY199I, GLY276I, GLY280I, GLY281I, GLY33J, GLY49J, GLY79J, GLY84J, GLY93J, HIS120J, HIS183I, HIS195I, HIS221I, HIS230I, HIS28J, HIS306I, HIS331I, HIS375I, HIS54I, ILE102I, ILE106J, ILE107J, ILE228I, ILE31J, ILE333I, LEU134I, LEU227I, LEU80I, LEU89J, LEU95J, LYS12J, LYS307I, LYS51J, MET117J, MET141I, PHE102J, PHE110J, PHE133I, PHE156I, PHE226I, PHE312I, PHE55I, PHE79I, PHE99I, PRO100J, PRO158I, PRO222I, PRO231I, PRO243I, PRO52I, PRO87J, PRO96J, PRO9J, SER157I, SER30J, SER310I, SER83J, THR118J, THR122J, THR137I, THR244I, THR308I, THR351I, THR50J, THR7J, THR91J, THR97I, TRP108J, TRP13J, TRP242I, TRP277I, TRP282I, TRP304I, TYR119J, TYR138I, TYR154I, TYR182I, TYR245I, TYR80J, TYR98J, VAL135I, VAL14J, VAL298I, VAL58I, VAL82J, VAL97J, VAL98I
• I-K: ALA159I, ALA59K, ALA66K, ARG197I, ARG99K, ASP180I, CYS181I, CYS92K, GLN155I, HIS53K, HIS56K, HIS91K, HIS95K, LYS27K, LYS68K, MET28K, MET51K, MET98K, PHE133I, PHE156I, PHE57K, PHE97K, PRO158I, PRO160I, PRO179I, PRO94K, PRO96K, SER157I, THR93K, TYR154I, TYR182I, VAL178I, VAL58K
• I-L: GLN146L, VAL219I
• I-M: ALA103I, ALA103M, ALA123I, ALA123M, ALA53I, ALA53M, ALA56I, ALA56M, ALA57I, ALA57M, ARG101I, ARG101M, ARG104I, ARG104M, ASP109I, ASP109M, ASP124I, ASP124M, ASP76I, ASP76M, GLN60I, GLN60M, GLU112I, GLU112M, GLU126I, GLU126M, GLU5I, GLU5M, GLY352I, GLY352M, GLY77I, GLY77M, GLY78I, GLY78M, HIS375I, HIS375M, HIS54I, HIS54M, HIS94I, HIS94M, ILE102I, ILE102M, ILE125I, ILE125M, ILE75I, ILE75M, LEU119I, LEU119M, LEU120I, LEU120M, LEU127I, LEU127M, LYS354I, LYS354M, PHE114I, PHE114M, PHE79I, PHE79M, PHE99I, PHE99M, PRO121I, PRO121M, PRO81I, PRO81M, SER100I, SER100M, SER96I, SER96M, THR108I, THR108M, THR59I, THR59M, THR97I, THR97M, TYR110I, TYR110M, VAL111I, VAL111M, VAL113I, VAL113M, VAL58I, VAL58M, VAL98I, VAL98M
• I-N: ALA10I, ALA112N, ALA17I, ALA18I, ALA19I, ALA21I, ALA22I, ALA22N, ALA23I, ALA24I, ALA27I, ALA39I, ALA53N, ALA6I, ALA73N, ARG20I, ARG27N, ARG35I, ARG46I, ARG70I, ARG75N, ARG85N, ASN18N, ASN34N, ASN371I, ASN45N, ASN63N, ASN81N, ASP114N, ASP115I, ASP17N, ASP19N, ASP24N, ASP25I, ASP31I, ASP32I, ASP37N, ASP66N, ASP76I, CYS23N, CYS36N, CYS38N, CYS46N, CYS77N, CYS78N, CYS86N, CYS88N, GLN11I, GLN14I, GLN16I, GLN16N, GLN21N, GLN30I, GLN372I, GLN60I, GLN61I, GLN68N, GLU113N, GLU12I, GLU33I, GLU38I, GLU5I, GLU7I, GLY128N, GLY15I, GLY29I, GLY374I, GLY40N, GLY41N, GLY49N, GLY69I, GLY73I, GLY77I, GLY79N, GLY84N, HIS120N, HIS375I, ILE123N, ILE126N, ILE20N, ILE35N, ILE36I, ILE64I, ILE72I, ILE72N, ILE75I, LEU119I, LEU120I, LEU26I, LEU356I, LEU373I, LEU37I, LEU43N, LEU52N, LYS129N, LYS354I, LYS51N, MET74I, PHE114I, PHE62I, PRO116I, PRO121I, PRO125N, PRO34I, PRO40I, PRO47N, PRO48N, PRO87N, SER124N, SER369I, SER39N, SER42N, SER83N, THR118I, THR118N, THR13I, THR355I, THR44N, THR50N, THR54N, THR59I, THR65N, THR8I, TRP26N, TYR119N, TYR25N, TYR70N, TYR80N, VAL117I, VAL127N, VAL370I, VAL58I, VAL63I, VAL71I, VAL82N
• I-O: ASP31I, ASP32I, GLN30I, GLN76O, GLU33I, LYS73O, PRO34I
• J-K: ALA103J, ALA112J, ALA130J, ALA50K, ALA53J, ALA55J, ALA59J, ALA66K, ALA73J, ARG75J, ARG99J, ASN47K, ASN54K, ASP114J, ASP115J, CYS109J, CYS92K, GLU101J, GLU113J, GLU49K, GLY111J, GLY128J, GLY69K, HIS53K, HIS56K, HIS91K, HIS95K, ILE106J, ILE126J, ILE72J, LEU71J, LYS129J, LYS68K, LYS73K, LYS74K, MET117J, MET28K, MET51K, MET71K, MET72K, MET98K, PHE102J, PHE110J, PHE97K, PRO100J, PRO125J, PRO52K, PRO70K, PRO94K, PRO96K, SER131J, SER56J, THR54J, THR93K, TRP108J, TYR70J, TYR74J, TYR98J, VAL127J, VAL58J, VAL97J
• J-M: ALA10M, ALA112J, ALA17M, ALA18M, ALA19M, ALA21M, ALA22J, ALA22M, ALA23M, ALA24M, ALA27M, ALA39M, ALA53J, ALA6M, ALA73J, ARG20M, ARG27J, ARG35M, ARG46M, ARG70M, ARG75J, ARG85J, ASN18J, ASN34J, ASN371M, ASN45J, ASN63J, ASN81J, ASP114J, ASP115M, ASP17J, ASP19J, ASP24J, ASP25M, ASP31M, ASP32M, ASP37J, ASP66J, ASP76M, CYS23J, CYS36J, CYS38J, CYS46J, CYS77J, CYS78J, CYS86J, CYS88J, GLN11M, GLN14M, GLN16J, GLN16M, GLN21J, GLN30M, GLN372M, GLN60M, GLN61M, GLN68J, GLN9M, GLU113J, GLU12M, GLU33M, GLU38M, GLU5M, GLU7M, GLY128J, GLY15M, GLY374M, GLY40J, GLY41J, GLY49J, GLY69M, GLY73M, GLY77M, GLY79J, GLY84J, HIS120J, HIS375M, ILE123J, ILE126J, ILE20J, ILE35J, ILE36M, ILE64M, ILE72J, ILE72M, ILE75M, LEU119M, LEU120M, LEU26M, LEU356M, LEU373M, LEU37M, LEU43J, LEU52J, LYS129J, LYS354M, LYS51J, MET74M, PHE114M, PHE62M, PRO116M, PRO121M, PRO125J, PRO34M, PRO40M, PRO47J, PRO48J, PRO87J, SER124J, SER369M, SER39J, SER42J, SER83J, THR118J, THR118M, THR13M, THR355M, THR44J, THR50J, THR54J, THR59M, THR65J, THR8M, TRP26J, TYR119J, TYR25J, TYR70J, TYR80J, VAL117M, VAL127J, VAL370M, VAL58M, VAL63M, VAL71M, VAL82J
• K-L: ALA20K, ALA26K, ALA65L, ALA76L, ARG48K, ASN47K, ASN74L, ASP127L, ASP130L, ASP18K, ASP24K, ASP75L, CYS60L, GLN100L, GLU105K, GLU31K, GLU34K, GLU49K, GLU66L, GLU75K, GLY126L, GLY19K, GLY62L, GLY67L, GLY70L, GLY72L, GLY99L, HIS36K, HIS61L, ILE21K, ILE25K, ILE46K, ILE69L, LEU35K, LEU73L, LYS101K, LYS27K, LYS29K, LYS38K, LYS68L, LYS74K, MET28K, PRO33K, PRO71L, PRO81L, THR125L, THR32K, THR79L, THR98L, TRP78L, TYR124L, TYR30K, TYR77L, TYR80L, VAL103K, VAL22K, VAL23K
• K-M: ASP31M, ASP32M, GLN76K, GLU33M, LYS73K, PRO34M
• M-N: ALA103M, ALA103N, ALA116N, ALA11N, ALA130M, ALA309M, ALA53M, ALA55N, ALA56M, ALA57M, ARG101M, ARG104M, ARG107M, ARG10N, ARG132M, ARG197M, ARG278M, ARG301M, ARG305M, ARG311M, ARG99N, ASN104N, ASN229M, ASN34N, ASN81N, ASN90N, ASP105N, ASP114N, ASP115N, ASP180M, ASP198M, ASP224M, ASP24N, ASP299M, ASP302M, ASP32N, ASP334M, ASP8N, CYS109N, CYS121N, CYS181M, CYS196M, CYS23N, CYS29N, CYS78N, CYS88N, GLN155M, GLN300M, GLN378M, GLU101N, GLU106M, GLU223M, GLU225M, GLU303M, GLU332M, GLU92N, GLU94N, GLY105M, GLY136M, GLY199M, GLY276M, GLY280M, GLY281M, GLY33N, GLY49N, GLY79N, GLY84N, GLY93N, HIS120N, HIS183M, HIS195M, HIS221M, HIS230M, HIS28N, HIS306M, HIS331M, HIS375M, HIS54M, ILE102M, ILE106N, ILE107N, ILE228M, ILE31N, ILE333M, LEU134M, LEU227M, LEU80M, LEU89N, LEU95N, LYS12N, LYS307M, LYS51N, MET117N, MET141M, PHE102N, PHE110N, PHE133M, PHE156M, PHE226M, PHE312M, PHE55M, PHE79M, PHE99M, PRO100N, PRO158M, PRO222M, PRO231M, PRO243M, PRO52M, PRO87N, PRO96N, PRO9N, SER157M, SER30N, SER310M, SER83N, THR118N, THR122N, THR137M, THR244M, THR308M, THR351M, THR50N, THR7N, THR91N, THR97M, TRP108N, TRP13N, TRP242M, TRP277M, TRP282M, TRP304M, TYR119N, TYR138M, TYR154M, TYR182M, TYR245M, TYR80N, TYR98N, VAL135M, VAL14N, VAL298M, VAL58M, VAL82N, VAL97N, VAL98M
• M-O: ALA159M, ALA59O, ALA66O, ARG197M, ARG99O, ASP180M, CYS181M, CYS92O, GLN155M, HIS53O, HIS56O, HIS91O, HIS95O, LYS27O, LYS68O, MET28O, MET51O, MET98O, PHE156M, PHE57O, PHE97O, PRO158M, PRO160M, PRO179M, PRO94O, PRO96O, SER157M, THR93O, TYR154M, TYR182M, VAL178M, VAL58O
• M-P: ASP198M, GLN146P, GLU223M, PRO144P, PRO222M, THR125P, VAL219M
• N-O: ALA103N, ALA112N, ALA130N, ALA50O, ALA53N, ALA55N, ALA59N, ALA73N, ARG75N, ARG99N, ASN47O, ASN54O, ASP114N, ASP115N, CYS109N, CYS92O, GLU101N, GLU113N, GLU49O, GLY111N, GLY128N, GLY69O, HIS53O, HIS56O, HIS91O, HIS95O, ILE106N, ILE126N, ILE72N, LEU71N, LYS129N, LYS68O, LYS73O, LYS74O, MET28O, MET51O, MET71O, MET72O, MET98O, PHE102N, PHE110N, PHE97O, PRO100N, PRO125N, PRO52O, PRO70O, PRO94O, PRO96O, SER131N, SER56N, THR54N, THR93O, TRP108N, TYR70N, TYR74N, TYR98N, VAL127N, VAL58N, VAL97N
• O-P: ALA26O, ALA65P, ALA76P, ARG48O, ASN74P, ASP127P, ASP130P, ASP18O, ASP24O, ASP75P, CYS60P, GLN100P, GLU105O, GLU31O, GLU34O, GLU49O, GLU66P, GLU75O, GLY126P, GLY19O, GLY62P, GLY67P, GLY70P, GLY72P, HIS36O, HIS61P, ILE25O, ILE46O, ILE69P, LEU35O, LEU73P, LYS101O, LYS27O, LYS29O, LYS38O, LYS68P, LYS74O, MET28O, PRO33O, PRO71P, THR125P, THR32O, THR79P, THR98P, TRP78P, TYR124P, TYR30O, TYR77P, VAL103O, VAL22O, VAL23O