2GAC

t152c mutant glycosylasparaginase from flavobacterium meningosepticum

• Total interactions analyzed: 6
• Total true interactions: 6
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 190
  • Norm. En. per Res.: -6.4082
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-263.2722	-11.3435	-942.943	-1217.5587	190	49	32	33597	1	27	32
A-C	0.0	21.7515	-19.0381	2.7134	46	0	3	1285	0	16	15
A-D	-36.6628	-25.8329	-204.52	-267.0157	65	15	4	7666	2	22	10
B-C	-37.8562	-24.2226	-205.48	-267.5588	61	15	4	7609	2	22	9
B-D	-15.2915	-46.7976	-145.897	-207.9862	73	8	8	6354	15	32	14
C-D	-274.9229	-9.7986	-929.971	-1214.6925	195	49	33	33818	1	27	30

Interface residues

• A-B: ALA157B, ALA160B, ALA167B, ALA174B, ALA17A, ALA189B, ALA199B, ALA200B, ALA202B, ALA21A, ALA259B, ALA268B, ALA278B, ALA31A, ALA34A, ALA67A, ALA80A, ALA92A, ARG180B, ARG286B, ARG40A, ARG49A, ARG56A, ARG59A, ARG62A, ARG93A, ASN12A, ASN163B, ASN18A, ASN195B, ASN261B, ASN276B, ASN285B, ASN3A, ASN73A, ASN75A, ASN87A, ASP107A, ASP159B, ASP183B, ASP194B, ASP281B, ASP33A, ASP44A, ASP58A, ASP60A, ASP66A, ASP71A, CYS152B, CYS168B, CYS68A, CYS81A, GLN161B, GLN254B, GLN282B, GLU127A, GLU129A, GLU131A, GLU134A, GLU196B, GLU20A, GLU265B, GLU288B, GLU36A, GLU43A, GLU48A, GLU72A, GLU83A, GLY106A, GLY14A, GLY154B, GLY162B, GLY166B, GLY172B, GLY179B, GLY182B, GLY188B, GLY190B, GLY204B, GLY256B, GLY264B, GLY267B, GLY274B, GLY284B, GLY28A, GLY29A, GLY38A, GLY52A, GLY54A, GLY55A, GLY61A, GLY77A, HIS16A, HIS178B, HIS216B, HIS280B, ILE153B, ILE156B, ILE186B, ILE187B, ILE197B, ILE258B, ILE69A, ILE6A, ILE76A, ILE89A, LEU104A, LEU123A, LEU124A, LEU136A, LEU158B, LEU15A, LEU164B, LEU191B, LEU25A, LEU260B, LEU287B, LEU32A, LEU41A, LEU65A, LEU8A, LYS130A, LYS133A, LYS176B, LYS23A, LYS262B, LYS263B, LYS27A, LYS283B, LYS30A, LYS37A, LYS4A, LYS86A, MET103A, MET155B, MET173B, MET177B, MET70A, MET82A, MET96A, PHE13A, PHE192B, PHE257B, PHE275B, PHE277B, PRO185B, PRO228B, PRO290B, PRO57A, PRO5A, PRO88A, SER128A, SER165B, SER171B, SER184B, SER26A, SER50A, SER78A, SER90A, SER9A, THR10A, THR169B, THR170B, THR201B, THR203B, THR215B, THR64A, TRP11A, TRP132A, TRP135A, TRP22A, TYR175B, TYR266B, TYR53A, TYR74A, VAL102A, VAL105A, VAL181B, VAL193B, VAL19A, VAL219B, VAL24A, VAL279B, VAL35A, VAL39A, VAL42A, VAL51A, VAL63A, VAL79A, VAL7A
• A-C: ALA80A, ALA80C, ARG59A, ARG59C, ARG62A, ARG62C, ASP107A, ASP107C, ASP58A, ASP58C, ASP60A, ASP60C, ASP66A, ASP66C, CYS81A, CYS81C, GLN116C, GLU111A, GLU111C, GLU83C, GLY106A, GLY106C, GLY108A, GLY108C, HIS101A, HIS101C, LEU104A, LEU104C, MET103A, MET103C, MET82A, MET82C, PHE112A, PHE112C, PRO100A, PRO100C, SER115A, SER115C, THR64A, THR64C, THR99A, THR99C, VAL105A, VAL105C, VAL79A, VAL79C
• A-D: ALA109A, ALA174D, ALA80A, ALA94A, ARG180D, ARG211D, ARG238D, ARG245D, ARG246D, ASN244D, ASN73A, ASN75A, ASP107A, ASP183D, ASP71A, CYS68A, GLN116A, GLU111A, GLU207D, GLU208D, GLU72A, GLU97A, GLY106A, GLY108A, GLY179D, GLY182D, GLY206D, GLY247D, GLY77A, HIS101A, HIS178D, HIS205D, ILE186D, ILE210D, ILE239D, ILE242D, ILE76A, LEU104A, LEU110A, LEU217D, LYS176D, LYS248D, LYS98A, MET103A, MET173D, MET177D, MET70A, MET96A, PHE112A, PRO100A, PRO185D, SER115A, SER78A, THR212D, THR99A, TYR175D, TYR74A, VAL102A, VAL105A, VAL181D, VAL209D, VAL213D, VAL243D, VAL79A, VAL95A
• B-C: ALA109C, ALA174B, ALA80C, ALA94C, ARG180B, ARG211B, ARG238B, ARG245B, ARG246B, ASN244B, ASN73C, ASN75C, ASP107C, ASP183B, ASP71C, GLU111C, GLU207B, GLU208B, GLU72C, GLY106C, GLY108C, GLY179B, GLY182B, GLY206B, GLY247B, GLY77C, HIS101C, HIS178B, ILE186B, ILE210B, ILE239B, ILE242B, ILE76C, LEU104C, LEU110C, LEU217B, LYS176B, LYS241B, LYS248B, LYS98C, MET103C, MET173B, MET177B, MET70C, MET96C, PHE112C, PRO100C, PRO185B, SER78C, THR212B, THR99C, TYR175B, TYR74C, VAL102C, VAL105C, VAL181B, VAL209B, VAL213B, VAL243B, VAL79C, VAL95C
• B-D: ALA189B, ALA189D, ARG211B, ARG211D, ARG226B, ARG238B, ARG238D, ARG245B, ARG245D, ASN195B, ASN195D, ASN223B, ASN223D, ASP194B, ASP194D, GLN224B, GLN224D, GLU196B, GLU196D, GLU207B, GLU207D, GLU220B, GLU220D, GLU234B, GLU234D, GLY188B, GLY188D, GLY198D, GLY214B, GLY214D, HIS216B, HIS216D, ILE186B, ILE186D, ILE187B, ILE187D, ILE197B, ILE197D, ILE210B, ILE210D, ILE242B, ILE242D, LEU164D, LEU191B, LEU191D, LEU217B, LEU217D, LEU221B, LEU221D, LYS241B, LYS241D, LYS262B, LYS262D, PHE192B, PHE192D, PRO185B, PRO185D, THR212B, THR212D, THR215B, THR215D, VAL181B, VAL181D, VAL193B, VAL193D, VAL209B, VAL209D, VAL213B, VAL213D, VAL218B, VAL218D, VAL219B, VAL219D
• C-D: ALA157D, ALA160D, ALA167D, ALA174D, ALA17C, ALA189D, ALA199D, ALA200D, ALA202D, ALA21C, ALA259D, ALA268D, ALA278D, ALA31C, ALA34C, ALA67C, ALA80C, ALA92C, ARG180D, ARG286D, ARG40C, ARG49C, ARG56C, ARG59C, ARG62C, ARG93C, ASN12C, ASN163D, ASN18C, ASN195D, ASN261D, ASN276D, ASN285D, ASN3C, ASN73C, ASN75C, ASN87C, ASP107C, ASP159D, ASP183D, ASP194D, ASP273D, ASP281D, ASP33C, ASP44C, ASP58C, ASP60C, ASP66C, ASP71C, CYS152D, CYS168D, CYS232D, CYS270D, CYS68C, CYS81C, GLN161D, GLN254D, GLN282D, GLU127C, GLU129C, GLU131C, GLU134C, GLU196D, GLU20C, GLU265D, GLU288D, GLU36C, GLU43C, GLU48C, GLU72C, GLU83C, GLY106C, GLY14C, GLY154D, GLY162D, GLY166D, GLY172D, GLY179D, GLY182D, GLY188D, GLY190D, GLY204D, GLY256D, GLY264D, GLY267D, GLY274D, GLY284D, GLY28C, GLY29C, GLY38C, GLY52C, GLY54C, GLY55C, GLY61C, GLY77C, HIS16C, HIS178D, HIS205D, HIS216D, HIS280D, ILE153D, ILE156D, ILE186D, ILE187D, ILE197D, ILE258D, ILE69C, ILE6C, ILE76C, ILE89C, LEU104C, LEU123C, LEU124C, LEU136C, LEU158D, LEU15C, LEU164D, LEU191D, LEU25C, LEU260D, LEU287D, LEU32C, LEU41C, LEU65C, LEU8C, LYS130C, LYS133C, LYS176D, LYS23C, LYS262D, LYS263D, LYS27C, LYS283D, LYS30C, LYS37C, LYS4C, LYS86C, MET103C, MET155D, MET173D, MET177D, MET70C, MET82C, MET96C, PHE13C, PHE192D, PHE257D, PHE275D, PHE277D, PRO185D, PRO228D, PRO290D, PRO57C, PRO5C, PRO88C, SER128C, SER165D, SER171D, SER184D, SER26C, SER50C, SER78C, SER90C, SER9C, THR10C, THR169D, THR170D, THR201D, THR203D, THR215D, THR289D, THR64C, TRP11C, TRP132C, TRP135C, TRP22C, TYR175D, TYR266D, TYR53C, TYR74C, VAL102C, VAL105C, VAL181D, VAL193D, VAL19C, VAL219D, VAL24C, VAL279D, VAL35C, VAL39C, VAL42C, VAL51C, VAL63C, VAL79C, VAL7C