2G82

high resolution structures of thermus aquaticus glyceraldehyde-3- phosphate dehydrogenase: role of 220's loop motion in catalysis

• Total interactions analyzed: 28
• Total true interactions: 17
• Strongest Interaction:
  • Chains: R-C
  • Int. Res.: 22
  • Norm. En. per Res.: -5.63
• Hub Node: O(4)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
O-P	-148.3678	-109.6827	-640.043	-898.0935	183	19	20	26705	20	58	39
O-Q	-33.3999	-40.4832	-116.947	-190.8301	54	3	2	4301	1	46	21
O-R	-33.5572	-31.146	-377.818	-442.5212	126	10	14	15791	2	40	54
O-D	-8.6513	-10.2824	-6.4511	-25.3848	14	1	0	318	2	22	16
P-Q	-42.035	-31.2314	-374.721	-447.9874	128	9	14	15653	2	41	55
P-R	-20.639	-25.7783	-109.833	-156.2503	54	2	2	4131	0	46	21
Q-R	-164.1512	-105.0066	-632.194	-901.3519	183	17	19	26585	20	58	38
Q-C	0.0	11.1879	-4.7353	6.4526	13	0	0	251	0	4	3
Q-D	-27.7185	-62.9565	-34.8498	-125.5247	23	4	0	1480	4	15	12
R-A	-15.2821	-14.4584	-4.391	-34.1315	11	1	0	186	2	18	10
R-C	-26.964	-60.5775	-36.3191	-123.8606	22	2	0	1390	4	15	10
A-B	-159.0339	-104.4029	-620.422	-883.8588	182	20	19	26342	20	58	38
A-C	-21.147	-36.6992	-116.835	-174.6812	54	2	2	4286	1	46	21
A-D	-40.9344	-31.0632	-373.095	-445.0925	127	7	14	15487	2	40	54
B-C	-41.218	-30.7555	-376.343	-448.3165	126	7	14	15722	2	40	55
B-D	-25.9129	-25.6658	-115.307	-166.8857	53	3	2	4195	0	46	21
C-D	-140.9293	-103.5372	-620.554	-865.0205	182	16	19	26291	20	58	38

Interface residues

• O-P: ALA170O, ALA170P, ALA195O, ALA195P, ALA197O, ALA197P, ALA198O, ALA198P, ALA199O, ALA199P, ALA210O, ALA210P, ALA228O, ALA228P, ALA234O, ALA234P, ALA243O, ALA243P, ALA293O, ALA293P, ALA298O, ALA298P, ARG193O, ARG193P, ARG194O, ARG194P, ARG196O, ARG196P, ARG223O, ARG223P, ARG230O, ARG230P, ARG247P, ASN201O, ASN201P, ASN301O, ASN301P, ASP186O, ASP186P, ASP191O, ASP191P, ASP225O, ASP225P, ASP240O, ASP240P, ASP275O, ASP275P, ASP281O, ASP281P, ASP292O, ASP292P, GLN182O, GLN182P, GLN280O, GLN280P, GLU168O, GLU168P, GLU248O, GLU248P, GLU274O, GLU274P, GLU276O, GLU276P, GLY208O, GLY208P, GLY222O, GLY222P, GLY226O, GLY226P, GLY236O, GLY236P, GLY300O, GLY300P, HIS176O, HIS176P, ILE200O, ILE200P, ILE202O, ILE202P, ILE203O, ILE203P, ILE238O, ILE238P, ILE241O, ILE241P, ILE277O, ILE277P, ILE282O, ILE282P, LEU171O, LEU171P, LEU192O, LEU192P, LEU220O, LEU220P, LEU229O, LEU229P, LEU244O, LEU244P, LEU245O, LEU245P, LEU279O, LEU279P, LEU295O, LEU295P, LEU299O, LEU299P, LYS169O, LYS169P, LYS190O, LYS190P, LYS211O, LYS211P, LYS221O, LYS221P, LYS294O, LYS294P, LYS297O, LYS297P, LYS304O, LYS304P, MET172O, MET172P, MET227O, MET227P, MET302O, MET302P, PHE224O, PHE224P, PHE306O, PHE306P, PRO204O, PRO204P, PRO232O, PRO232P, SER177O, SER177P, SER237O, SER237P, SER239O, SER239P, THR173O, THR173P, THR174O, THR174P, THR205O, THR205P, THR206O, THR206P, THR207O, THR207P, THR233O, THR233P, THR235O, THR235P, THR242O, THR242P, THR273O, THR273P, THR296O, THR296P, TRP308O, TRP308P, TYR178O, TYR178P, TYR309O, TYR309P, VAL167O, VAL167P, VAL175O, VAL175P, VAL231O, VAL231P, VAL249O, VAL249P, VAL278O, VAL278P, VAL283O, VAL283P, VAL303O, VAL303P, VAL305O, VAL305P
• O-Q: ALA199O, ALA199Q, ALA234O, ALA234Q, ARG50O, ARG50Q, ASP275O, ASP275Q, ASP281O, ASP281Q, ASP45O, ASP45Q, GLN280O, GLN280Q, GLU274O, GLU274Q, GLU276O, GLU276Q, HIS40O, HIS40Q, HIS49O, HIS49Q, ILE200O, ILE200Q, ILE277O, ILE277Q, ILE282O, ILE282Q, ILE47O, ILE47Q, LEU279O, LEU279Q, LYS294O, LYS294Q, LYS36O, LYS36Q, LYS43O, LYS43Q, MET284O, MET284Q, SER46O, SER46Q, THR235O, THR235Q, THR273O, THR273Q, TYR44O, TYR44Q, TYR48O, TYR48Q, VAL278O, VAL278Q, VAL283O, VAL283Q
• O-R: ALA195O, ALA195R, ALA197O, ALA197R, ALA198O, ALA198R, ALA199O, ALA199R, ALA234O, ALA234R, ALA39O, ALA39R, ARG10O, ARG10R, ARG13O, ARG13R, ARG17O, ARG17R, ARG183O, ARG183R, ARG193O, ARG193R, ARG194O, ARG194R, ARG196O, ARG196R, ARG230O, ARG230R, ARG50O, ARG50R, ASN180O, ASN180R, ASN201O, ASN201R, ASN311O, ASN311R, ASP181O, ASP181R, ASP186O, ASP186R, ASP191O, ASP191R, ASP31O, ASP31R, ASP34O, ASP34R, ASP45O, ASP45R, GLN14O, GLN14R, GLN182O, GLN182R, GLN280O, GLN280R, GLU312O, GLU312R, GLY7O, GLY7R, GLY9O, GLY9R, HIS176O, HIS176R, HIS189O, HIS189R, HIS40O, HIS40R, HIS49O, HIS49R, ILE200O, ILE200R, ILE203O, ILE203R, ILE47O, ILE47R, LEU184O, LEU184R, LEU185O, LEU185R, LEU187O, LEU187R, LEU192O, LEU192R, LEU32O, LEU32R, LEU38O, LEU38R, LEU41O, LEU41R, LEU42R, LYS190O, LYS190R, LYS36O, LYS36R, LYS43O, LYS43R, PHE8O, PHE8R, PRO188O, PRO188R, PRO232O, PRO232R, SER177O, SER177R, SER46O, SER46R, THR179O, THR179R, THR233O, THR233R, THR235O, THR235R, THR33O, THR33R, THR37O, THR37R, THR94R, TYR178O, TYR178R, TYR44O, TYR44R, TYR48O, TYR48R, TYR57O, TYR57R, VAL231O, VAL231R
• O-D: ARG140D, ASP101D, ASP124D, ASP34O, ASP58O, ASP59O, GLN60O, GLU108D, HIS142D, ILE143D, LEU107D, LYS104D, SER139D, TYR63O
• P-Q: ALA195P, ALA195Q, ALA197P, ALA197Q, ALA198P, ALA198Q, ALA199P, ALA199Q, ALA234P, ALA234Q, ALA39P, ALA39Q, ARG10P, ARG10Q, ARG13P, ARG13Q, ARG17P, ARG17Q, ARG183P, ARG183Q, ARG193P, ARG193Q, ARG194P, ARG194Q, ARG196P, ARG196Q, ARG230P, ARG230Q, ARG50P, ARG50Q, ASN180P, ASN180Q, ASN201P, ASN201Q, ASN311P, ASN311Q, ASP181P, ASP181Q, ASP186P, ASP186Q, ASP191P, ASP191Q, ASP31P, ASP31Q, ASP34P, ASP34Q, ASP45P, ASP45Q, GLN14P, GLN14Q, GLN182P, GLN182Q, GLN280P, GLN280Q, GLU312P, GLU312Q, GLY7P, GLY7Q, GLY9P, GLY9Q, HIS176P, HIS176Q, HIS189P, HIS189Q, HIS40P, HIS40Q, HIS49P, HIS49Q, ILE200P, ILE200Q, ILE203P, ILE203Q, ILE47P, ILE47Q, LEU184P, LEU184Q, LEU185P, LEU185Q, LEU187P, LEU187Q, LEU192P, LEU192Q, LEU32P, LEU32Q, LEU38P, LEU38Q, LEU41P, LEU41Q, LEU42P, LEU42Q, LYS190P, LYS190Q, LYS36P, LYS36Q, LYS43P, LYS43Q, PHE8P, PHE8Q, PRO188P, PRO188Q, PRO232P, PRO232Q, SER177P, SER177Q, SER46P, SER46Q, THR179P, THR179Q, THR233P, THR233Q, THR235P, THR235Q, THR33P, THR33Q, THR37P, THR37Q, THR94P, THR94Q, TYR178P, TYR178Q, TYR44P, TYR44Q, TYR48P, TYR48Q, TYR57P, TYR57Q, VAL231P, VAL231Q
• P-R: ALA199P, ALA199R, ALA234P, ALA234R, ARG50P, ARG50R, ASP275P, ASP275R, ASP281P, ASP281R, ASP45P, ASP45R, GLN280P, GLN280R, GLU274P, GLU274R, GLU276P, GLU276R, HIS40P, HIS40R, HIS49P, HIS49R, ILE200P, ILE200R, ILE277P, ILE277R, ILE282P, ILE282R, ILE47P, ILE47R, LEU279P, LEU279R, LYS294P, LYS294R, LYS36P, LYS36R, LYS43P, LYS43R, MET284P, MET284R, SER46P, SER46R, THR235P, THR235R, THR273P, THR273R, TYR44P, TYR44R, TYR48P, TYR48R, VAL278P, VAL278R, VAL283P, VAL283R
• Q-R: ALA170Q, ALA170R, ALA195Q, ALA195R, ALA197Q, ALA197R, ALA198Q, ALA198R, ALA199Q, ALA199R, ALA210Q, ALA210R, ALA228Q, ALA228R, ALA234Q, ALA234R, ALA243Q, ALA243R, ALA293Q, ALA293R, ALA298Q, ALA298R, ARG193Q, ARG193R, ARG194Q, ARG194R, ARG196Q, ARG196R, ARG223Q, ARG223R, ARG230Q, ARG230R, ARG247R, ASN201Q, ASN201R, ASN301Q, ASN301R, ASP186Q, ASP186R, ASP191Q, ASP191R, ASP225Q, ASP225R, ASP240Q, ASP240R, ASP275Q, ASP275R, ASP281Q, ASP281R, ASP292Q, ASP292R, GLN182Q, GLN182R, GLN280Q, GLN280R, GLU168Q, GLU168R, GLU248Q, GLU248R, GLU274Q, GLU274R, GLU276Q, GLU276R, GLY208Q, GLY208R, GLY222Q, GLY222R, GLY226Q, GLY226R, GLY236Q, GLY236R, GLY300Q, GLY300R, HIS176Q, HIS176R, ILE200Q, ILE200R, ILE202Q, ILE202R, ILE203Q, ILE203R, ILE238Q, ILE238R, ILE241Q, ILE241R, ILE277Q, ILE277R, ILE282Q, ILE282R, LEU171Q, LEU171R, LEU192Q, LEU192R, LEU220Q, LEU220R, LEU229Q, LEU229R, LEU244Q, LEU244R, LEU245Q, LEU245R, LEU279Q, LEU279R, LEU295Q, LEU295R, LEU299Q, LEU299R, LYS169Q, LYS169R, LYS190Q, LYS190R, LYS211Q, LYS211R, LYS221R, LYS294Q, LYS294R, LYS297Q, LYS297R, LYS304Q, LYS304R, MET158R, MET172Q, MET172R, MET227Q, MET227R, MET302Q, MET302R, PHE224Q, PHE224R, PHE306Q, PHE306R, PRO204Q, PRO204R, PRO232Q, PRO232R, SER177Q, SER177R, SER237Q, SER237R, SER239Q, SER239R, THR173Q, THR173R, THR174Q, THR174R, THR205Q, THR205R, THR206Q, THR206R, THR207Q, THR207R, THR233Q, THR233R, THR235Q, THR235R, THR242Q, THR242R, THR273Q, THR273R, THR296Q, THR296R, TRP308Q, TRP308R, TYR178Q, TYR178R, TYR309Q, TYR309R, VAL167Q, VAL167R, VAL175Q, VAL175R, VAL231Q, VAL231R, VAL249Q, VAL249R, VAL278Q, VAL278R, VAL283Q, VAL283R, VAL303Q, VAL303R, VAL305Q, VAL305R
• Q-C: ASN301C, ASN301Q, GLU248C, GLU248Q, GLY300C, GLY300Q, LEU244C, LEU299C, LEU299Q, MET302C, MET302Q, THR250C, THR250Q
• Q-D: ALA214D, ALA251Q, ALA256Q, ARG223D, ARG247Q, GLU168D, GLU248Q, GLU252Q, GLU253Q, GLY222D, GLY300Q, LEU220D, LEU244D, LYS169D, LYS221D, LYS246D, PHE165Q, PHE224D, PRO218D, SER219D, THR250Q, VAL167D, VAL249Q
• R-A: ALA100R, ARG140R, ASP101R, ASP124R, ASP58A, ASP59A, GLN60A, HIS142R, ILE143R, LEU107R, LYS104R
• R-C: ALA214R, ALA251C, ALA298C, ARG223R, ARG247C, GLU168R, GLU248C, GLU252C, GLU253C, GLY222R, GLY300C, LEU220R, LEU244R, LYS169R, LYS221R, LYS246R, PHE165C, PHE224R, PRO218R, SER219R, THR250C, VAL249C
• A-B: ALA170A, ALA170B, ALA195A, ALA195B, ALA197A, ALA197B, ALA198A, ALA198B, ALA199A, ALA199B, ALA210A, ALA210B, ALA228A, ALA228B, ALA234A, ALA234B, ALA243A, ALA243B, ALA293A, ALA293B, ALA298A, ALA298B, ARG193A, ARG193B, ARG194A, ARG194B, ARG196A, ARG196B, ARG223A, ARG223B, ARG230A, ARG230B, ARG247A, ASN201A, ASN201B, ASN301A, ASN301B, ASP186A, ASP186B, ASP191A, ASP191B, ASP225A, ASP225B, ASP240A, ASP240B, ASP275A, ASP275B, ASP281A, ASP281B, ASP292A, ASP292B, GLN182A, GLN182B, GLN280A, GLN280B, GLU168A, GLU168B, GLU248A, GLU248B, GLU274A, GLU274B, GLU276A, GLU276B, GLY208A, GLY208B, GLY222A, GLY222B, GLY226A, GLY226B, GLY236A, GLY236B, GLY300A, GLY300B, HIS176A, HIS176B, ILE200A, ILE200B, ILE202A, ILE202B, ILE203A, ILE203B, ILE238A, ILE238B, ILE241A, ILE241B, ILE277A, ILE277B, ILE282A, ILE282B, LEU171A, LEU171B, LEU192A, LEU192B, LEU220A, LEU220B, LEU229A, LEU229B, LEU244A, LEU244B, LEU245A, LEU245B, LEU279A, LEU279B, LEU295A, LEU295B, LEU299A, LEU299B, LYS169A, LYS169B, LYS190A, LYS190B, LYS211A, LYS211B, LYS294A, LYS294B, LYS297A, LYS297B, LYS304A, LYS304B, MET158B, MET172A, MET172B, MET227A, MET227B, MET302A, MET302B, PHE224A, PHE224B, PHE306A, PHE306B, PRO204A, PRO204B, PRO232A, PRO232B, SER177A, SER177B, SER237A, SER237B, SER239A, SER239B, THR173A, THR173B, THR174A, THR174B, THR205A, THR205B, THR206A, THR206B, THR207A, THR207B, THR233A, THR233B, THR235A, THR235B, THR242A, THR242B, THR273A, THR273B, THR296A, THR296B, TRP308A, TRP308B, TYR178A, TYR178B, TYR309A, TYR309B, VAL167A, VAL167B, VAL175A, VAL175B, VAL231A, VAL231B, VAL249A, VAL249B, VAL278A, VAL278B, VAL283A, VAL283B, VAL303A, VAL303B, VAL305A, VAL305B
• A-C: ALA199A, ALA199C, ALA234A, ALA234C, ARG50A, ARG50C, ASP275A, ASP275C, ASP281A, ASP281C, ASP45A, ASP45C, GLN280A, GLN280C, GLU274A, GLU274C, GLU276A, GLU276C, HIS40A, HIS40C, HIS49A, HIS49C, ILE200A, ILE200C, ILE277A, ILE277C, ILE282A, ILE282C, ILE47A, ILE47C, LEU279A, LEU279C, LYS294A, LYS294C, LYS36A, LYS36C, LYS43A, LYS43C, MET284A, MET284C, SER46A, SER46C, THR235A, THR235C, THR273A, THR273C, TYR44A, TYR44C, TYR48A, TYR48C, VAL278A, VAL278C, VAL283A, VAL283C
• A-D: ALA195A, ALA195D, ALA197A, ALA197D, ALA198A, ALA198D, ALA199A, ALA199D, ALA234A, ALA234D, ALA39A, ALA39D, ARG10A, ARG10D, ARG13A, ARG13D, ARG17A, ARG17D, ARG183A, ARG183D, ARG193A, ARG193D, ARG194A, ARG194D, ARG196A, ARG196D, ARG230A, ARG230D, ARG50A, ARG50D, ASN180A, ASN180D, ASN201A, ASN201D, ASN311A, ASN311D, ASP181A, ASP181D, ASP186A, ASP186D, ASP191A, ASP191D, ASP31A, ASP31D, ASP34A, ASP34D, ASP45A, ASP45D, GLN14A, GLN14D, GLN182A, GLN182D, GLN280A, GLN280D, GLU312A, GLU312D, GLY7A, GLY7D, GLY9A, GLY9D, HIS176A, HIS176D, HIS189A, HIS189D, HIS40A, HIS40D, HIS49A, HIS49D, ILE200A, ILE200D, ILE203A, ILE203D, ILE47A, ILE47D, LEU184A, LEU184D, LEU185A, LEU185D, LEU187A, LEU187D, LEU192A, LEU192D, LEU32A, LEU32D, LEU38A, LEU38D, LEU41A, LEU41D, LEU42D, LYS190A, LYS190D, LYS36A, LYS36D, LYS43A, LYS43D, PHE8A, PHE8D, PRO188A, PRO188D, PRO232A, PRO232D, SER177A, SER177D, SER46A, SER46D, THR179A, THR179D, THR233A, THR233D, THR235A, THR235D, THR33A, THR33D, THR37A, THR37D, THR94A, THR94D, TYR178A, TYR178D, TYR44A, TYR44D, TYR48A, TYR48D, TYR57A, TYR57D, VAL231A, VAL231D
• B-C: ALA195B, ALA195C, ALA197B, ALA197C, ALA198B, ALA198C, ALA199B, ALA199C, ALA234B, ALA234C, ALA39B, ALA39C, ARG10B, ARG10C, ARG13B, ARG13C, ARG17B, ARG17C, ARG183B, ARG183C, ARG193B, ARG193C, ARG194B, ARG194C, ARG196B, ARG196C, ARG230B, ARG230C, ARG50B, ARG50C, ASN180B, ASN180C, ASN201B, ASN201C, ASN311B, ASN311C, ASP181B, ASP181C, ASP186B, ASP186C, ASP191B, ASP191C, ASP31B, ASP31C, ASP34B, ASP34C, ASP45B, ASP45C, GLN14B, GLN14C, GLN182B, GLN182C, GLN280B, GLN280C, GLU312B, GLU312C, GLY7B, GLY9B, GLY9C, HIS176B, HIS176C, HIS189B, HIS189C, HIS40B, HIS40C, HIS49B, HIS49C, ILE200B, ILE200C, ILE203B, ILE203C, ILE47B, ILE47C, LEU184B, LEU184C, LEU185B, LEU185C, LEU187B, LEU187C, LEU192B, LEU192C, LEU32B, LEU32C, LEU38B, LEU38C, LEU41B, LEU41C, LEU42B, LEU42C, LYS190B, LYS190C, LYS36B, LYS36C, LYS43B, LYS43C, PHE8B, PHE8C, PRO188B, PRO188C, PRO232B, PRO232C, SER177B, SER177C, SER46B, SER46C, THR179B, THR179C, THR233B, THR233C, THR235B, THR235C, THR33B, THR33C, THR37B, THR37C, THR94B, TYR178B, TYR178C, TYR44B, TYR44C, TYR48B, TYR48C, TYR57B, TYR57C, VAL231B, VAL231C
• B-D: ALA199B, ALA199D, ALA234B, ALA234D, ARG50B, ARG50D, ASP275B, ASP275D, ASP281B, ASP281D, ASP45B, ASP45D, GLN280B, GLN280D, GLU274B, GLU274D, GLU276B, GLU276D, HIS40B, HIS40D, HIS49B, HIS49D, ILE200B, ILE200D, ILE277B, ILE277D, ILE282B, ILE282D, ILE47B, ILE47D, LEU279B, LEU279D, LYS294D, LYS36B, LYS36D, LYS43B, LYS43D, MET284B, MET284D, SER46B, SER46D, THR235B, THR235D, THR273B, THR273D, TYR44B, TYR44D, TYR48B, TYR48D, VAL278B, VAL278D, VAL283B, VAL283D
• C-D: ALA170C, ALA170D, ALA195C, ALA195D, ALA197C, ALA197D, ALA198C, ALA198D, ALA199C, ALA199D, ALA210C, ALA210D, ALA228C, ALA228D, ALA234C, ALA234D, ALA243C, ALA243D, ALA293C, ALA293D, ALA298C, ALA298D, ARG193C, ARG193D, ARG194C, ARG194D, ARG196C, ARG196D, ARG223C, ARG223D, ARG230C, ARG230D, ASN201C, ASN201D, ASN301C, ASN301D, ASP186C, ASP186D, ASP191C, ASP191D, ASP225C, ASP225D, ASP240C, ASP240D, ASP275C, ASP275D, ASP281C, ASP281D, ASP292C, ASP292D, GLN182C, GLN182D, GLN280C, GLN280D, GLU168C, GLU168D, GLU248C, GLU248D, GLU274C, GLU274D, GLU276C, GLU276D, GLY208C, GLY208D, GLY222C, GLY222D, GLY226C, GLY226D, GLY236C, GLY236D, GLY300C, GLY300D, HIS176C, HIS176D, ILE200C, ILE200D, ILE202C, ILE202D, ILE203C, ILE203D, ILE238C, ILE238D, ILE241C, ILE241D, ILE277C, ILE277D, ILE282C, ILE282D, LEU171C, LEU171D, LEU192C, LEU192D, LEU220C, LEU220D, LEU229C, LEU229D, LEU244C, LEU244D, LEU245C, LEU245D, LEU279C, LEU279D, LEU295C, LEU295D, LEU299C, LEU299D, LYS169C, LYS169D, LYS190C, LYS190D, LYS211C, LYS211D, LYS294C, LYS294D, LYS297C, LYS297D, LYS304C, LYS304D, MET158C, MET158D, MET172C, MET172D, MET227C, MET227D, MET302C, MET302D, PHE224C, PHE224D, PHE306C, PHE306D, PRO204C, PRO204D, PRO232C, PRO232D, SER177C, SER177D, SER237C, SER237D, SER239C, SER239D, THR173C, THR173D, THR174C, THR174D, THR205C, THR205D, THR206C, THR206D, THR207C, THR207D, THR233C, THR233D, THR235C, THR235D, THR242C, THR242D, THR273C, THR273D, THR296C, THR296D, TRP308C, TRP308D, TYR178C, TYR178D, TYR309C, TYR309D, VAL167C, VAL167D, VAL175C, VAL175D, VAL231C, VAL231D, VAL249C, VAL249D, VAL278C, VAL278D, VAL283C, VAL283D, VAL303C, VAL303D, VAL305C, VAL305D