2G4D

crystal structure of human senp1 mutant (c603s) in complex with sumo-1

• Total interactions analyzed: 6
• Total true interactions: 3
• Strongest Interaction:
  • Chains: C-D
  • Int. Res.: 108
  • Norm. En. per Res.: -5.4891
• Hub Node: A(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-132.1617	-134.0458	-333.197	-599.4045	110	27	2	10630	13	38	27
A-C	-39.7895	7.7494	-78.4631	-110.5032	33	6	0	2982	0	28	38
C-D	-119.9066	-134.9596	-337.955	-592.8212	108	24	2	10490	13	39	27

Interface residues

• A-B: ALA504A, ALA508A, ALA72B, ARG449A, ARG454A, ARG511A, ARG631A, ARG63B, ARG70B, ASN464A, ASN467A, ASN472A, ASN476A, ASN494A, ASN599A, ASN60B, ASN74B, ASP441A, ASP456A, ASP468A, ASP602A, ASP73B, ASP86B, CYS535A, GLN29B, GLN440A, GLN597A, GLN69B, GLN92B, GLN94B, GLU442A, GLU446A, GLU469A, GLU67B, GLU79B, GLU83B, GLU89B, GLU93B, GLY28B, GLY531A, GLY600A, GLY604A, GLY68B, GLY81B, GLY96B, GLY97B, HIS43B, HIS529A, HIS533A, HIS75B, ILE27B, ILE452A, ILE470A, ILE471A, ILE528A, ILE71B, LEU44B, LEU450A, LEU463A, LEU466A, LEU501A, LEU530A, LEU62B, LEU65B, LEU80B, LYS455A, LYS48B, LYS500A, LYS510A, LYS514A, LYS515A, LYS78B, MET552A, MET59B, MET605A, MET82B, PHE448A, PHE473A, PHE493A, PHE496A, PHE497A, PHE498A, PHE606A, PHE64B, PHE66B, PRO527A, PRO58B, SER31B, SER551A, SER601A, SER603A, SER61B, THR451A, THR453A, THR459A, THR495A, THR499A, THR503A, THR513A, THR76B, THR95B, TRP465A, TRP512A, TRP534A, TYR91B, VAL443A, VAL509A, VAL532A, VAL87B, VAL90B
• A-C: ARG481A, ARG481C, ARG542A, ARG641A, ARG641C, ASP522A, ASP522C, GLU480A, GLU480C, GLU484A, GLU484C, GLY486A, GLY486C, HIS640A, HIS640C, LEU487A, LEU487C, LYS483A, LYS483C, LYS485A, LYS485C, LYS642A, LYS642C, PRO488A, PRO488C, SER482A, SER482C, SER489A, SER489C, VAL490A, VAL490C, VAL521A, VAL521C
• C-D: ALA504C, ALA508C, ALA72D, ARG449C, ARG454C, ARG511C, ARG631C, ARG63D, ARG70D, ASN464C, ASN467C, ASN472C, ASN476C, ASN494C, ASN599C, ASN60D, ASN74D, ASP441C, ASP456C, ASP468C, ASP602C, ASP73D, ASP86D, CYS535C, GLN29D, GLN440C, GLN597C, GLN69D, GLN92D, GLN94D, GLU442C, GLU446C, GLU469C, GLU67D, GLU79D, GLU83D, GLU89D, GLU93D, GLY28D, GLY531C, GLY600C, GLY604C, GLY68D, GLY81D, GLY96D, GLY97D, HIS43D, HIS529C, HIS533C, HIS75D, ILE27D, ILE452C, ILE470C, ILE471C, ILE528C, ILE71D, LEU44D, LEU450C, LEU463C, LEU466C, LEU501C, LEU530C, LEU62D, LEU65D, LEU80D, LYS455C, LYS48D, LYS500C, LYS510C, LYS514C, LYS515C, LYS78D, MET552C, MET59D, MET605C, MET82D, PHE448C, PHE473C, PHE493C, PHE496C, PHE497C, PHE498C, PHE606C, PHE64D, PHE66D, PRO527C, PRO58D, SER551C, SER601C, SER603C, SER61D, THR451C, THR453C, THR459C, THR495C, THR499C, THR503C, THR513C, THR76D, THR95D, TRP465C, TRP512C, TRP534C, TYR91D, VAL443C, VAL509C, VAL532C, VAL90D