2G3K

crystal structure of the c-terminal domain of vps28

• Total interactions analyzed: 21
• Total true interactions: 14
• Strongest Interaction:
  • Chains: C-F
  • Int. Res.: 35
  • Norm. En. per Res.: -3.2881
• Hub Node: A(6)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-9.7286	-58.1763	-181.061	-248.9659	76	12	7	8127	5	22	19
A-C	-14.2257	25.4388	-100.242	-89.0289	49	3	1	3965	0	17	18
A-D	-7.317	12.2579	-86.8838	-81.9429	49	2	2	3597	0	17	16
A-E	0.0	5.9493	-29.7549	-23.8056	27	0	0	1588	2	14	13
A-F	-2.1295	28.2538	-162.397	-136.2727	54	1	16	6556	0	6	6
A-G	0.0	0.0	-15.9169	-15.9169	12	0	0	639	0	4	4
B-C	0.0	0.0	-13.7707	-13.7707	17	0	1	626	0	4	5
B-D	0.0	-15.218	39.6131	24.3951	16	13	1	1418	2	4	4
C-E	0.0	12.5077	-22.5287	-10.021	14	0	0	979	0	4	5
C-F	-19.4337	-40.0695	-55.581	-115.0842	35	3	0	2500	5	14	14
D-E	0.0	24.0672	-151.937	-127.8698	55	7	15	6287	0	4	5
D-G	0.0	0.9287	-17.3501	-16.4214	21	1	0	1049	0	12	9
E-F	-2.6401	4.1759	-71.7074	-70.1716	48	3	2	3526	0	16	19
E-G	-11.5098	-8.9391	-106.928	-127.3769	50	3	2	3947	3	17	20

Interface residues

• A-B: ALA154B, ALA156B, ALA166B, ALA173B, ALA182A, ALA182B, ARG190A, ARG190B, ARG193A, ARG199A, ARG208A, ASN149A, ASN159A, ASN159B, ASN170B, ASN172B, ASN189A, ASN210A, ASP165B, ASP175B, ASP194A, ASP195A, ASP204A, GLN176B, GLU155A, GLU155B, GLU183A, GLU183B, GLY158B, HIS178A, HIS178B, ILE161B, ILE186A, ILE186B, ILE188A, ILE203A, ILE206A, ILE206B, ILE209A, LEU167B, LEU169B, LEU177B, LEU180A, LEU180B, LEU181A, LEU181B, LEU184A, LEU184B, LEU185A, LEU185B, LEU202A, LYS151B, LYS168B, LYS174A, LYS174B, LYS201A, LYS211A, PHE160B, PRO179A, PRO179B, SER187A, SER187B, SER200A, THR157B, THR162B, THR192A, TRP205A, TYR152A, TYR152B, TYR171B, TYR234B, TYR238B, VAL153B, VAL163B, VAL191A, VAL207A
• A-C: ALA166A, ALA173A, ALA233C, ALA239C, ARG199C, ARG224C, ASN159A, ASN170A, ASN172A, ASN198C, ASP165A, ASP175A, ASP195C, ASP204C, ASP229C, GLN176A, GLN222C, GLU155A, GLU183A, GLU197C, GLU225C, GLU231C, GLY158A, HIS178A, ILE161A, LEU167A, LEU169A, LEU177A, LEU180A, LEU181A, LEU202C, LEU226C, LEU227C, LEU230C, LEU232C, LYS168A, LYS174A, LYS201C, LYS235C, PHE196C, PHE228C, PRO179A, SER200C, SER236C, THR162A, THR221C, TRP205C, TYR171A, VAL163A
• A-D: ALA166D, ALA173D, ALA182D, ALA233A, ARG199A, ARG208A, ARG224A, ASN159D, ASN170D, ASN172D, ASN198A, ASP165D, ASP175D, ASP195A, ASP204A, ASP229A, GLN176D, GLN222A, GLU183D, GLU197A, GLU220A, GLU225A, GLU231A, HIS178D, ILE161D, ILE223A, LEU167D, LEU169D, LEU177D, LEU180D, LEU181D, LEU226A, LEU227A, LEU230A, LEU232A, LYS168D, LYS174D, LYS201A, LYS235A, PHE196A, PHE228A, PRO179D, SER200A, SER236A, THR162D, THR221A, TRP205A, TYR171D, VAL163D
• A-E: ALA166A, ARG224A, ARG224E, ASN170A, ASN170E, ASP165A, ASP165E, GLU220A, GLU220E, GLU231A, GLU231E, ILE223A, LEU167A, LEU167E, LEU169A, LEU169E, LEU227A, LEU227E, LYS168A, LYS168E, LYS235A, LYS235E, PHE228A, PHE228E, THR221A, TYR171E, TYR234E
• A-F: ALA150A, ALA150F, ALA154A, ALA154F, ALA156A, ALA156F, ALA239A, ALA239F, ARG190A, ARG190F, ASN149A, ASN149F, ASN159A, ASN159F, ASP165A, ASP165F, GLU155A, GLU155F, GLY158A, GLY158F, ILE161A, ILE161F, LEU169A, LEU169F, LEU240A, LEU240F, LEU241A, LEU241F, LYS151A, LYS151F, LYS168A, LYS168F, LYS235A, LYS235F, PHE148A, PHE148F, PHE160A, PHE160F, PHE237A, PHE237F, THR157A, THR157F, THR162A, THR162F, TYR152A, TYR152F, TYR234A, TYR234F, TYR238A, TYR238F, VAL153A, VAL153F, VAL191A, VAL191F
• A-G: ARG224A, ARG224G, GLN222A, GLN222G, GLU220A, GLU220G, GLU225A, GLU225G, THR219A, THR219G, THR221A, THR221G
• B-C: ALA239C, ASN170B, ASN172B, ASP194C, ASP195C, GLU197C, LEU169B, LEU240C, LEU241C, LYS168B, LYS235C, PHE148C, PHE196C, PHE237C, SER236C, TYR171B, TYR238C
• B-D: ALA150B, ALA173D, ARG190B, ASN149B, ASN172D, ASP175D, ASP216D, GLN176D, GLU155B, GLY215D, ILE214D, LYS151B, LYS174D, SER213D, TYR152B, VAL191B
• C-E: ARG224C, ARG224E, GLN222C, GLN222E, GLU220C, GLU220E, GLU225C, GLU225E, ILE223E, PHE228C, THR219C, THR219E, THR221C, THR221E
• C-F: ALA166C, ALA166F, ARG224C, ARG224F, ASN170C, ASN170F, ASN172F, ASP165C, ASP165F, GLU220C, GLU220F, GLU225C, GLU231C, GLU231F, ILE161C, ILE161F, ILE223C, ILE223F, LEU167C, LEU167F, LEU169C, LEU169F, LEU227C, LEU227F, LYS168C, LYS168F, LYS235C, PHE228C, PHE228F, THR162C, THR221C, THR221F, TYR171C, TYR171F, TYR234F
• D-E: ALA150D, ALA150E, ALA154D, ALA154E, ALA156D, ALA156E, ALA239D, ALA239E, ARG190D, ARG190E, ASN149D, ASN149E, ASN159D, ASN159E, ASP165D, ASP165E, GLU155D, GLU155E, GLY158D, GLY158E, ILE161D, ILE161E, LEU169D, LEU169E, LEU240D, LEU240E, LEU241D, LEU241E, LYS151D, LYS151E, LYS168D, LYS168E, LYS235D, PHE148D, PHE148E, PHE160D, PHE160E, PHE237D, PHE237E, SER236D, THR157D, THR157E, THR162D, THR162E, TYR152D, TYR152E, TYR234D, TYR234E, TYR238D, TYR238E, VAL153D, VAL153E, VAL163E, VAL191D, VAL191E
• D-G: ALA166G, ARG224D, ARG224G, ASN170D, ASN170G, ASP165G, GLU220D, GLU220G, GLU231D, GLU231G, LEU167D, LEU167G, LEU169D, LEU169G, LEU227D, LEU227G, LYS168D, LYS168G, PHE228D, THR221D, TYR171G
• E-F: ALA166F, ALA173F, ALA239E, ARG199E, ARG208E, ARG224E, ASN159F, ASN170F, ASN172F, ASN198E, ASP165F, ASP175F, ASP195E, ASP229E, GLN176F, GLN222E, GLU183F, GLU197E, GLU220E, GLU225E, GLU231E, GLY215F, HIS178F, ILE161F, ILE214F, ILE223E, LEU167F, LEU169F, LEU177F, LEU180F, LEU181F, LEU226E, LEU227E, LEU232E, LYS168F, LYS174F, LYS201E, LYS235E, PHE196E, PHE228E, PRO179F, SER200E, SER236E, THR162F, THR221E, TRP205E, TYR171F, VAL163F
• E-G: ALA166E, ALA173E, ALA182E, ALA233G, ARG199G, ARG208G, ARG224G, ASN159E, ASN170E, ASN172E, ASN198G, ASN210E, ASP165E, ASP175E, ASP195G, ASP204G, ASP229G, GLN176E, GLN222G, GLU183E, GLU197G, GLU220G, GLU225G, GLU231G, GLY215E, HIS178E, ILE209E, ILE214E, ILE223G, LEU167E, LEU169E, LEU177E, LEU180E, LEU181E, LEU226G, LEU227G, LEU232G, LYS174E, LYS201G, LYS235G, PHE196G, PHE228G, PRO179E, SER200G, SER236G, THR162E, THR221G, TRP205G, TYR171E, VAL163E