2FUL

crystal structure of the c-terminal domain of s. cerevisiae eif5

• Total interactions analyzed: 15
• Total true interactions: 7
• Strongest Interaction:
  • Chains: C-E
  • Int. Res.: 100
  • Norm. En. per Res.: -3.0314
• Hub Node: A(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-7.1726	-2.4711	-154.432	-164.0756	76	3	4	6716	0	36	29
A-C	-9.4439	4.713	-148.304	-153.0349	67	3	3	6352	1	37	29
B-C	-13.7573	-9.9217	-147.051	-170.73	67	2	3	6040	2	37	30
C-E	-49.8353	-15.8645	-237.443	-303.1429	100	8	1	9529	2	51	33
D-E	-33.7805	15.8183	-154.541	-172.5032	63	4	2	6222	3	34	27
D-F	-8.1495	8.8856	-144.506	-143.7699	68	1	4	6169	0	37	27
E-F	-12.1224	29.3135	-120.887	-103.696	65	1	2	5192	0	28	23

Interface residues

• A-B: ALA276A, ALA277A, ALA292B, ARG330B, ASN242A, ASN283A, ASN323B, ASP249A, ASP249B, ASP280A, ASP284B, CYS289B, CYS294B, GLN247A, GLN247B, GLN258A, GLN293B, GLU239A, GLU239B, GLU244A, GLU244B, GLU250A, GLU250B, GLU253A, GLU253B, GLU257B, GLU261B, GLU278A, GLU335B, GLU376B, GLY236B, GLY252B, GLY326B, GLY327B, GLY333B, HIS336B, ILE255B, ILE287B, LEU245B, LEU248A, LEU248B, LEU256B, LEU279A, LEU291B, LEU334B, LYS263B, LYS274A, LYS275A, LYS286B, LYS337B, LYS370B, LYS371B, LYS375B, LYS380B, PHE240A, PHE331B, PHE372B, PRO238A, PRO238B, PRO374B, SER237A, SER237B, SER243A, SER369B, SER378B, THR246A, THR246B, TRP254A, TRP254B, TYR251A, TYR251B, VAL241A, VAL281A, VAL290B, VAL373B, VAL377B
• A-C: ALA276C, ALA277C, ALA292A, ARG330A, ASN242C, ASN283C, ASN323A, ASP249A, ASP280C, ASP284A, CYS289A, CYS294A, GLN247A, GLN247C, GLN293A, GLU239C, GLU244A, GLU244C, GLU250A, GLU250C, GLU253A, GLU257A, GLU257C, GLU278C, GLU335A, GLU376A, GLY252A, GLY326A, GLY327A, GLY333A, HIS336A, ILE255A, ILE287A, ILE340A, LEU245A, LEU248A, LEU248C, LEU256A, LEU279C, LEU291A, LEU334A, LYS274C, LYS275C, LYS286A, LYS337A, LYS370A, LYS371A, LYS375A, LYS380A, PHE240C, PHE331A, PHE372A, PRO238C, PRO374A, SER243C, SER369A, SER378A, THR246A, THR246C, TRP254A, TRP254C, TYR251A, VAL241C, VAL281C, VAL290A, VAL373A, VAL377A
• B-C: ALA276B, ALA277B, ALA292C, ARG330C, ASN242B, ASN283B, ASN323C, ASP249B, ASP249C, ASP280B, CYS289C, CYS294C, GLN247B, GLN247C, GLN293C, GLU239B, GLU244B, GLU250B, GLU250C, GLU253C, GLU257B, GLU278B, GLU335C, GLU376C, GLY236B, GLY252C, GLY326C, GLY327C, GLY333C, ILE255C, ILE287C, ILE340C, LEU245C, LEU248B, LEU248C, LEU256C, LEU279B, LEU291C, LEU295C, LEU334C, LYS274B, LYS275B, LYS286C, LYS337C, LYS370C, LYS371C, LYS375C, LYS380C, PHE240B, PHE372C, PRO238B, PRO374C, SER237B, SER243B, SER369C, SER378C, THR246B, THR246C, TRP254B, TRP254C, TYR251B, TYR251C, VAL241B, VAL281B, VAL290C, VAL373C, VAL377C
• C-E: ALA305E, ALA309C, ALA384C, ALA384E, ALA385C, ALA385E, ALA395E, ARG363C, ARG382C, ARG383C, ASN265E, ASN283C, ASN302E, ASN308C, ASN308E, ASN352C, ASN352E, ASN353C, ASN353E, ASP299E, ASP338E, ASP354C, ASP354E, ASP403E, ASP404E, GLN349E, GLU271E, GLU303E, GLU306E, GLU319C, GLU321C, GLU329C, GLU358C, GLU359C, GLU360C, GLU396E, GLU405C, GLU405E, GLU407E, GLY365C, ILE304E, ILE314C, ILE340E, ILE346E, ILE355C, ILE356C, ILE389C, ILE389E, LEU282C, LEU315C, LEU339E, LEU342E, LEU343C, LEU343E, LEU347E, LEU392E, LEU406E, LYS313C, LYS322C, LYS345E, LYS367C, LYS370C, LYS371C, LYS375C, LYS379C, LYS380C, LYS386C, LYS386E, MET362C, PHE310C, PHE311C, PHE324C, PHE364C, PHE372C, PHE388E, PRO285C, PRO318C, PRO341E, PRO344E, PRO387E, SER268E, SER357C, SER368C, SER369C, SER378C, THR312C, THR317C, THR366C, THR390E, THR394E, TRP391E, TYR273C, TYR320C, TYR351C, TYR351E, VAL301E, VAL316C, VAL348E, VAL377C, VAL381C
• D-E: ALA276D, ALA277D, ALA292E, ARG330E, ASN242D, ASN283D, ASN323E, ASP249E, ASP280D, CYS289E, CYS294E, GLN247D, GLN293E, GLU239D, GLU244D, GLU244E, GLU250D, GLU250E, GLU253E, GLU278D, GLU335E, GLU376E, GLY252E, GLY326E, GLY327E, GLY333E, ILE255E, LEU245D, LEU245E, LEU248D, LEU248E, LEU256E, LEU279D, LEU291E, LEU295E, LEU334E, LYS263E, LYS274D, LYS275D, LYS286E, LYS337E, LYS370E, LYS371E, LYS375E, LYS380E, PHE240D, PHE372E, PRO238D, PRO238E, PRO374E, SER243D, SER369E, SER378E, THR246D, THR246E, TRP254D, TRP254E, TYR251E, VAL241D, VAL281D, VAL290E, VAL373E, VAL377E
• D-F: ALA276F, ALA277F, ALA292D, ARG330D, ASN242F, ASN283F, ASN323D, ASP249D, ASP280F, ASP284D, CYS289D, CYS294D, GLN247F, GLN258F, GLN293D, GLU239F, GLU244D, GLU244F, GLU250D, GLU250F, GLU253D, GLU253F, GLU257D, GLU257F, GLU278F, GLU335D, GLU376D, GLY252D, GLY326D, GLY327D, GLY333D, ILE255D, ILE287D, LEU245D, LEU248D, LEU248F, LEU256D, LEU279F, LEU291D, LEU334D, LYS263D, LYS274F, LYS275F, LYS286D, LYS337D, LYS370D, LYS371D, LYS375D, LYS379D, LYS380D, PHE240F, PHE372D, PRO238F, PRO374D, SER243F, SER369D, SER378D, THR246D, THR246F, TRP254D, TRP254F, TYR251D, TYR251F, VAL241F, VAL281F, VAL290D, VAL373D, VAL377D
• E-F: ALA292F, ARG330F, ASN242E, ASN323F, ASP249F, ASP280E, ASP284F, CYS289F, CYS294F, GLN247E, GLN247F, GLN258E, GLN293F, GLU239E, GLU239F, GLU244E, GLU244F, GLU250E, GLU250F, GLU253E, GLU253F, GLU257E, GLU257F, GLU278E, GLU376F, GLY252F, GLY326F, GLY327F, ILE255F, ILE287F, LEU245E, LEU245F, LEU248F, LEU256F, LEU279E, LEU291F, LEU295F, LEU334F, LYS263F, LYS275E, LYS286F, LYS337F, LYS370F, LYS371F, LYS375F, LYS379F, PHE240E, PHE372F, PRO238E, PRO238F, PRO285F, PRO374F, SER243E, SER243F, THR246E, THR246F, TRP254E, TRP254F, TYR251E, TYR251F, VAL241E, VAL281E, VAL290F, VAL373F, VAL377F