2FMN

ala177val mutant of e. coli methylenetetrahydrofolate reductase complex with ly309887

• Total interactions analyzed: 3
• Total true interactions: 3
• Strongest Interaction:
  • Chains: A-C
  • Int. Res.: 127
  • Norm. En. per Res.: -3.5212
• Hub Node: A(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	0.0	0.0	-31.1099	-31.1099	31	0	2	1598	0	8	7
A-C	-76.2371	-32.5253	-338.426	-447.1884	127	17	12	14596	9	54	34
B-C	-34.853	-20.2439	-155.732	-210.8289	83	12	3	6458	7	38	35

Interface residues

• A-B: ALA11A, ALA11B, ALA17A, ALA17B, ALA6A, ALA6B, ARG266A, ARG266B, ARG9A, ARG9B, ASN13A, ASN13B, ASP10A, ASP10B, GLN14A, GLN14B, GLN8A, GLN8B, GLU18A, GLU18B, GLU267A, LEU12A, LEU12B, PHE3A, PHE3B, PHE4A, PHE4B, SER15A, SER15B, SER7A, SER7B
• A-C: ALA11A, ALA17A, ALA233C, ALA236A, ALA236C, ALA246A, ALA246C, ALA254A, ALA254C, ALA257A, ALA257C, ALA280A, ALA280C, ALA285A, ALA285C, ALA6A, ARG193C, ARG195C, ARG249A, ARG249C, ARG266C, ARG293A, ARG293C, ARG47A, ARG47C, ARG9A, ASN13A, ASN255A, ASN255C, ASP10A, ASP187C, ASP196C, ASP240A, ASP240C, ASP243A, ASP243C, ASP244A, ASP244C, ASP245A, ASP245C, ASP259A, ASP259C, CYS287A, CYS287C, GLN14A, GLN20A, GLN237A, GLN237C, GLN8A, GLU189C, GLU18A, GLU247A, GLU247C, GLU267C, GLU281A, GLU281C, GLY241A, GLY241C, GLY253A, GLY253C, GLY291A, GLY291C, GLY295A, HIS288A, HIS288C, HIS5A, ILE256A, ILE256C, ILE263A, ILE263C, ILE286A, ILE286C, LEU12A, LEU16A, LEU192C, LEU242A, LEU242C, LEU251A, LEU251C, LEU264C, LEU290A, LEU290C, LYS250A, LYS250C, LYS262A, LYS262C, MET235A, MET235C, MET238A, MET238C, MET258A, MET258C, MET260A, MET260C, MET282A, MET282C, PHE185C, PHE186C, PHE239A, PHE239C, PHE3A, PHE4A, PRO213A, PRO213C, PRO232C, PRO294A, PRO294C, SER15A, SER190C, SER283A, SER283C, SER7A, THR248A, THR248C, THR289A, THR289C, TRP234A, TRP234C, TYR191C, TYR284A, TYR284C, VAL188C, VAL19A, VAL252A, VAL252C, VAL261C, VAL292C
• B-C: ALA11B, ALA159C, ALA162C, ALA164C, ALA17B, ALA180B, ALA201B, ALA201C, ALA233C, ALA236C, ARG179B, ARG193B, ARG193C, ARG195B, ARG197B, ARG197C, ARG230C, ARG266B, ASN168C, ASN178B, ASN228C, ASP165C, ASP174B, ASP187C, ASP196B, ASP196C, ASP204B, ASP271B, CYS198B, CYS198C, GLN14B, GLN163C, GLN22B, GLN8B, GLU154C, GLU189C, GLU18B, GLU206B, GLU267B, GLY176B, GLY202B, GLY202C, GLY268B, ILE203B, ILE203C, ILE207B, ILE208B, ILE231C, ILE263B, LEU12B, LEU166C, LEU167C, LEU169C, LEU192B, LEU192C, LEU264B, LYS160C, LYS170B, LYS170C, LYS270B, MET235C, PHE194B, PHE194C, PRO153C, PRO232C, SER15B, SER161C, SER190C, SER200B, SER200C, SER265B, TRP234C, TYR191B, TYR191C, VAL155C, VAL173B, VAL177B, VAL188C, VAL199B, VAL19B, VAL205B, VAL229C, VAL269B