2FGW

x-ray structures of fragments from binding and nonbinding versions of a humanized anti-cd18 antibody: structural indications of the key role of vh residues 59 to 65

• Total interactions analyzed: 1
• Total true interactions: 1
• Strongest Interaction:
  • Chains: L-H
  • Int. Res.: 192
  • Norm. En. per Res.: 1.0125
• Hub Node: L(1)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
L-H	-17.9006	-16.1554	228.463	194.407	192	15	13	17712	2	25	19

Interface residues

• L-H: ALA130L, ALA136H, ALA147H, ALA148H, ALA179H, ALA43L, ALA49H, ALA97H, ARG100H, ARG109H, ARG211L, ARG38H, ARG63H, ARG98H, ASN137L, ASN138L, ASN158L, ASN210L, ASN31L, ASN34L, ASN61H, ASN92L, ASP112H, ASP122L, ASP155H, ASP167L, ASP170L, ASP1L, ASP228H, CYS134L, CYS151H, CYS214L, CYS227H, CYS88L, CYS96H, GLN100L, GLN116H, GLN124L, GLN160L, GLN182H, GLN37L, GLN38L, GLN39H, GLN62H, GLN89L, GLN90L, GLU123L, GLU161L, GLU165L, GLU187L, GLU213L, GLU46H, GLU6H, GLY101L, GLY115H, GLY117H, GLY144H, GLY145H, GLY150H, GLY173H, GLY185H, GLY212L, GLY41L, GLY42H, GLY44H, GLY50H, GLY91L, GLY99L, HIS175H, HIS35H, HIS55L, HIS60H, ILE117L, ILE48L, LEU125L, LEU135H, LEU135L, LEU136L, LEU149H, LEU152H, LEU175L, LEU179L, LEU181H, LEU181L, LEU186H, LEU189H, LEU33L, LEU45H, LEU46L, LEU4H, LEU54L, LEU94L, LYS126L, LYS154H, LYS169L, LYS190L, LYS207L, LYS220H, LYS221H, LYS225H, LYS39L, LYS42L, LYS43H, LYS45L, MET37H, PHE111H, PHE116L, PHE118L, PHE133H, PHE139L, PHE177H, PHE209L, PHE64H, PHE98L, PRO119L, PRO120L, PRO134H, PRO137H, PRO178H, PRO44L, PRO95L, PRO96L, SER114L, SER121L, SER127L, SER131H, SER131L, SER138H, SER139H, SER141H, SER143H, SER159L, SER162L, SER172H, SER174L, SER176L, SER177L, SER183H, SER184H, SER188H, SER190H, SER191H, SER197H, SER208L, SER226H, SER56L, SER59H, THR129L, THR142H, THR146H, THR164L, THR172L, THR176H, THR178L, THR180L, THR194H, THR206L, THR33H, THR53L, THR85L, THR93L, THR97L, TRP114H, TRP35L, TRP47H, TRP99H, TYR110H, TYR173L, TYR186L, TYR187H, TYR192L, TYR32L, TYR36L, TYR49L, TYR50L, TYR86L, TYR87L, TYR95H, VAL113H, VAL115L, VAL132H, VAL132L, VAL133L, VAL163L, VAL174H, VAL180H, VAL192H, VAL193H, VAL195H, VAL222H, VAL48H, VAL93H