2FG8

structure of human ferritin l chain

• Total interactions analyzed: 28
• Total true interactions: 15
• Strongest Interaction:
  • Chains: B-H
  • Int. Res.: 122
  • Norm. En. per Res.: -5.1475
• Hub Node: B(4)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-C	-25.5529	33.2628	-161.151	-153.4411	70	4	1	6399	1	30	35
A-D	-57.6327	-84.3136	-421.607	-563.5533	121	17	5	15271	14	55	44
A-E	-7.3343	8.9348	-149.351	-147.7506	62	9	2	6704	0	44	29
B-C	0.0	5.7513	-1.0631	4.6882	10	0	0	271	0	0	2
B-D	-13.9667	9.1282	-170.33	-175.1685	63	8	2	6805	0	42	29
B-G	-27.2951	11.4581	-173.734	-189.571	62	11	2	7088	0	43	28
B-H	-94.1103	-96.9316	-436.949	-627.9909	122	21	5	15137	15	56	43
C-D	-20.6023	14.351	-179.394	-185.6453	62	8	3	7031	1	43	29
C-G	-25.9132	7.9545	-169.45	-187.4087	64	13	2	6950	1	42	29
D-E	-23.6614	35.0984	-145.946	-134.509	71	2	1	6292	1	29	35
D-G	0.0	5.8038	-0.8666	4.9372	11	0	0	252	0	0	2
D-H	-27.16	35.3952	-151.915	-143.6798	70	4	1	6322	1	28	35
E-F	-77.5644	-99.7171	-430.814	-608.0954	120	20	6	15254	16	55	44
E-H	-9.7563	33.0379	-153.627	-130.3454	71	9	1	6479	1	28	35
F-H	-41.4655	9.7971	-165.79	-197.4584	63	13	2	6930	0	43	30

Interface residues

• A-C: ALA105C, ALA113C, ALA119C, ARG76A, ARG79A, ARG9A, ASN111C, ASN11A, ASN154C, ASN74A, ASP116C, ASP126A, ASP131A, ASP131C, ASP139C, ASP150C, CYS130A, CYS130C, GLN10A, GLN112C, GLN73A, GLN75A, GLN7A, GLU107C, GLU134A, GLU134C, GLU140C, GLU141C, GLY149C, GLY77A, GLY78A, HIS118A, HIS118C, HIS128A, HIS136A, HIS151C, HIS156C, ILE145C, ILE8A, LEU110C, LEU114C, LEU115C, LEU129A, LEU133C, LEU138C, LEU144C, LEU152C, LYS101C, LYS108C, LYS109C, LYS143C, LYS146C, LYS147C, LYS71A, MET104C, MET148C, MET72A, PHE132A, PHE137C, PRO127A, SER122A, SER122C, SER5A, SER6A, THR125A, THR135A, THR135C, THR153C, TYR12A, VAL142C
• A-D: ALA47A, ALA47D, ALA59A, ALA59D, ALA80A, ALA80D, ARG43A, ARG43D, ARG56A, ARG56D, ARG63A, ARG63D, ARG68A, ARG68D, ARG76A, ARG76D, ARG79A, ARG79D, ARG9A, ARG9D, ASN21A, ASN25A, ASN25D, ASN74A, ASN74D, ASP42A, ASP42D, ASP44A, ASP44D, ASP45A, ASP45D, ASP84A, ASP84D, ASP91A, ASP91D, GLN29A, GLN29D, GLN73A, GLN73D, GLN75A, GLN75D, GLN7A, GLN7D, GLN83A, GLN83D, GLU49A, GLU49D, GLU60A, GLU60D, GLU64A, GLU64D, GLU67A, GLU67D, GLU90A, GLU90D, GLU92A, GLU92D, GLY38A, GLY38D, GLY77A, GLY77D, GLY78A, GLY78D, HIS53A, HIS53D, ILE85A, ILE85D, ILE8A, ILE8D, LEU28A, LEU28D, LEU35A, LEU35D, LEU37A, LEU37D, LEU69A, LEU69D, LEU70A, LEU70D, LEU81A, LEU81D, LYS71A, LYS71D, LYS86A, LYS86D, LYS87A, LYS87D, MET72A, MET72D, PHE39A, PHE39D, PHE41A, PHE41D, PHE82A, PHE82D, PRO88A, PRO88D, SER31A, SER31D, SER36A, SER36D, SER52A, SER52D, SER5A, SER5D, SER6A, SER6D, THR33A, THR33D, TRP93A, TRP93D, TYR32A, TYR32D, TYR40A, TYR40D, TYR66A, TYR66D, VAL24A, VAL24D, VAL46A, VAL46D
• A-E: ALA163A, ALA163E, ALA47A, ARG157E, ARG172A, ARG172E, ARG43A, ASN154E, ASP150E, ASP178A, ASP42A, ASP44A, ASP45A, GLU162A, GLU162E, GLU167A, GLU167E, GLU171A, GLU171E, GLU49A, GLY149E, GLY159E, GLY160E, GLY164A, GLY166A, GLY166E, GLY94A, HIS151E, HIS156E, HIS177A, ILE145E, LEU152E, LEU155E, LEU158E, LEU165A, LEU165E, LEU169A, LEU169E, LEU173A, LEU173E, LEU175E, LEU48A, LYS146E, LYS147E, LYS176A, LYS176E, LYS95A, MET104E, MET148E, PHE170A, PHE170E, PHE41A, PRO161A, PRO161E, THR153E, THR174E, THR96A, TYR168A, TYR168E, TYR40A, VAL46A, VAL51A
• B-C: GLU162B, GLU162C, LEU165B, LEU165C, LEU169B, LEU169C, LEU173B, LEU173C, TYR168B, TYR168C
• B-D: ALA163B, ALA163D, ALA47B, ARG157D, ARG172B, ARG172D, ARG43B, ASN154D, ASP150D, ASP178B, ASP42B, ASP44B, ASP45B, GLU162B, GLU162D, GLU167B, GLU167D, GLU171B, GLU171D, GLU49B, GLY149D, GLY159D, GLY160D, GLY164B, GLY166B, GLY166D, GLY94B, HIS151D, HIS156D, HIS177B, ILE145D, LEU152D, LEU155D, LEU158D, LEU165B, LEU165D, LEU169B, LEU169D, LEU173B, LEU173D, LEU175D, LEU48B, LYS146D, LYS147D, LYS176B, LYS176D, LYS95B, MET104D, MET148D, PHE170B, PHE170D, PHE39B, PHE41B, PRO161B, PRO161D, THR153D, THR174D, THR96B, TYR168B, TYR168D, TYR40B, VAL46B, VAL51B
• B-G: ALA163B, ALA163G, ALA47G, ARG157B, ARG172B, ARG172G, ARG43G, ASN154B, ASP150B, ASP42G, ASP44G, ASP45G, GLU162B, GLU162G, GLU167B, GLU167G, GLU171B, GLU171G, GLU49G, GLY149B, GLY159B, GLY160B, GLY164G, GLY166B, GLY166G, HIS151B, HIS156B, HIS177G, ILE145B, LEU152B, LEU155B, LEU158B, LEU165B, LEU165G, LEU169B, LEU169G, LEU173B, LEU173G, LEU175B, LEU48G, LYS146B, LYS147B, LYS176B, LYS176G, LYS95G, MET104B, MET148B, PHE170B, PHE170G, PHE39G, PHE41G, PRO161B, PRO161G, PRO97G, SER52G, THR153B, THR174B, THR96G, TYR168B, TYR168G, VAL46G, VAL51G
• B-H: ALA47B, ALA47H, ALA59B, ALA59H, ALA80B, ALA80H, ARG43B, ARG43H, ARG56B, ARG56H, ARG63B, ARG63H, ARG68B, ARG68H, ARG76B, ARG76H, ARG79B, ARG79H, ARG9B, ARG9H, ASN21H, ASN25B, ASN25H, ASN74B, ASN74H, ASP42B, ASP42H, ASP44B, ASP44H, ASP45B, ASP45H, ASP84B, ASP84H, ASP91B, ASP91H, GLN29B, GLN29H, GLN73B, GLN73H, GLN75B, GLN75H, GLN7B, GLN7H, GLN83B, GLN83H, GLU49B, GLU49H, GLU60B, GLU60H, GLU64B, GLU64H, GLU67B, GLU67H, GLU90B, GLU90H, GLU92B, GLU92H, GLY38B, GLY38H, GLY77B, GLY77H, GLY78B, GLY78H, HIS53B, HIS53H, ILE85B, ILE85H, ILE8B, ILE8H, LEU28B, LEU28H, LEU35B, LEU35H, LEU37B, LEU37H, LEU69B, LEU69H, LEU70B, LEU70H, LEU81B, LEU81H, LYS71B, LYS71H, LYS86B, LYS86H, LYS87B, LYS87H, MET72B, MET72H, PHE39B, PHE39H, PHE41B, PHE41H, PHE82B, PHE82H, PRO88B, PRO88H, SER31B, SER31H, SER36B, SER36H, SER52B, SER52H, SER5B, SER5H, SER6B, SER6H, THR33B, THR33H, TRP93B, TRP93H, TYR32B, TYR32H, TYR34H, TYR40B, TYR40H, TYR66B, TYR66H, VAL24B, VAL24H, VAL46B, VAL46H
• C-D: ALA163C, ALA163D, ALA47D, ARG157C, ARG172C, ARG172D, ARG43D, ASN154C, ASP150C, ASP42D, ASP44D, ASP45D, GLU162C, GLU162D, GLU167C, GLU167D, GLU171C, GLU171D, GLU49D, GLY149C, GLY159C, GLY160C, GLY164D, GLY166C, GLY166D, GLY50D, GLY94D, HIS151C, HIS156C, HIS177D, ILE145C, LEU152C, LEU155C, LEU158C, LEU165C, LEU165D, LEU169C, LEU169D, LEU173C, LEU173D, LEU175C, LEU48D, LYS146C, LYS147C, LYS176C, LYS95D, MET104C, MET148C, PHE170C, PHE170D, PHE39D, PHE41D, PRO161C, PRO161D, THR153C, THR174C, THR96D, TYR168C, TYR168D, TYR40D, VAL46D, VAL51D
• C-G: ALA163C, ALA163G, ALA47C, ARG157G, ARG172C, ARG172G, ARG43C, ASN154G, ASP150G, ASP178C, ASP42C, ASP44C, ASP45C, GLU162C, GLU162G, GLU167C, GLU167G, GLU171C, GLU171G, GLU49C, GLY149G, GLY159G, GLY160G, GLY164C, GLY166C, GLY166G, GLY94C, HIS151G, HIS156G, HIS177C, ILE145G, LEU152G, LEU155G, LEU158G, LEU165C, LEU165G, LEU169C, LEU169G, LEU173C, LEU173G, LEU175G, LEU48C, LYS146G, LYS147G, LYS176C, LYS176G, LYS95C, MET104G, MET148G, PHE170C, PHE170G, PHE39C, PHE41C, PRO161C, PRO161G, PRO97C, SER52C, THR153G, THR174G, THR96C, TYR168C, TYR168G, VAL46C, VAL51C
• D-E: ALA105E, ALA113E, ALA119E, ARG76D, ARG79D, ARG9D, ASN111E, ASN11D, ASN154E, ASN74D, ASP116E, ASP126D, ASP131D, ASP131E, ASP139E, ASP150E, CYS130D, CYS130E, GLN10D, GLN112E, GLN73D, GLN75D, GLN7D, GLU107E, GLU134D, GLU134E, GLU140E, GLU141E, GLY149E, GLY77D, GLY78D, HIS118D, HIS118E, HIS128D, HIS136D, HIS151E, HIS156E, ILE145E, ILE8D, LEU110E, LEU114E, LEU115E, LEU129D, LEU133E, LEU138E, LEU144E, LEU152E, LEU70D, LYS101E, LYS108E, LYS109E, LYS143E, LYS146E, LYS147E, LYS71D, MET104E, MET148E, MET72D, PHE132D, PHE137E, PRO127D, SER122D, SER122E, SER5D, SER6D, THR125D, THR135D, THR135E, THR153E, TYR12D, VAL142E
• D-G: GLU162D, GLU162G, LEU165D, LEU165G, LEU169D, LEU169G, LEU173D, LEU173G, PRO161D, TYR168D, TYR168G
• D-H: ALA105D, ALA113D, ALA119D, ARG76H, ARG79H, ARG9H, ASN111D, ASN11H, ASN154D, ASN74H, ASP116D, ASP126H, ASP131D, ASP131H, ASP139D, ASP150D, CYS130D, CYS130H, GLN10H, GLN112D, GLN73H, GLN75H, GLN7H, GLU107D, GLU134D, GLU134H, GLU140D, GLU141D, GLY149D, GLY77H, GLY78H, HIS118D, HIS118H, HIS128H, HIS136H, HIS151D, HIS156D, ILE145D, ILE8H, LEU110D, LEU114D, LEU115D, LEU129H, LEU133D, LEU138D, LEU144D, LEU152D, LYS101D, LYS108D, LYS109D, LYS143D, LYS146D, LYS147D, LYS71H, MET104D, MET148D, MET72H, PHE132H, PHE137D, PRO127H, SER122D, SER122H, SER5H, SER6H, THR125H, THR135D, THR135H, THR153D, TYR12H, VAL142D
• E-F: ALA47E, ALA47F, ALA59E, ALA59F, ALA80E, ALA80F, ARG43E, ARG43F, ARG56E, ARG56F, ARG63E, ARG63F, ARG68E, ARG68F, ARG76E, ARG76F, ARG79E, ARG79F, ARG9E, ARG9F, ASN25E, ASN25F, ASN74E, ASN74F, ASP42E, ASP42F, ASP44E, ASP44F, ASP45E, ASP45F, ASP84E, ASP84F, ASP91E, ASP91F, GLN29E, GLN29F, GLN73E, GLN73F, GLN75E, GLN75F, GLN7E, GLN7F, GLN83E, GLN83F, GLU49E, GLU49F, GLU60E, GLU60F, GLU64E, GLU64F, GLU67E, GLU67F, GLU90E, GLU90F, GLU92E, GLU92F, GLY38E, GLY38F, GLY77E, GLY77F, GLY78E, GLY78F, HIS53E, HIS53F, ILE85E, ILE85F, ILE8E, ILE8F, LEU28E, LEU28F, LEU35E, LEU35F, LEU37E, LEU37F, LEU69E, LEU69F, LEU70E, LEU70F, LEU81E, LEU81F, LYS71E, LYS71F, LYS86E, LYS86F, LYS87E, LYS87F, MET72E, MET72F, PHE39E, PHE39F, PHE41E, PHE41F, PHE82E, PHE82F, PRO88E, PRO88F, SER31E, SER31F, SER36E, SER36F, SER52E, SER52F, SER5E, SER5F, SER6E, SER6F, THR33E, THR33F, TRP93E, TRP93F, TYR32E, TYR32F, TYR40E, TYR40F, TYR66E, TYR66F, VAL24E, VAL24F, VAL46E, VAL46F
• E-H: ALA105H, ALA113H, ALA119H, ARG76E, ARG79E, ARG9E, ASN111H, ASN11E, ASN154H, ASN74E, ASP116H, ASP126E, ASP131E, ASP131H, ASP139H, ASP150H, CYS130E, CYS130H, GLN10E, GLN112H, GLN73E, GLN75E, GLN7E, GLU107H, GLU134E, GLU134H, GLU140H, GLU141H, GLY149H, GLY77E, GLY78E, HIS118E, HIS118H, HIS128E, HIS136E, HIS151H, HIS156H, ILE145H, ILE8E, LEU110H, LEU114H, LEU115H, LEU129E, LEU133H, LEU138H, LEU144H, LEU152H, LEU70E, LYS101H, LYS108H, LYS109H, LYS143H, LYS146H, LYS147H, LYS71E, MET104H, MET148H, MET72E, PHE132E, PHE137H, PRO127E, SER122E, SER122H, SER5E, SER6E, THR125E, THR135E, THR135H, THR153H, TYR12E, VAL142H
• F-H: ALA163F, ALA163H, ALA47F, ARG157H, ARG172F, ARG172H, ARG43F, ASN154H, ASP150H, ASP178F, ASP42F, ASP44F, ASP45F, GLU162F, GLU162H, GLU167F, GLU167H, GLU171F, GLU171H, GLU49F, GLY149H, GLY159H, GLY160H, GLY164F, GLY166F, GLY166H, GLY94F, HIS151H, HIS156H, HIS177F, ILE145H, LEU152H, LEU155H, LEU158H, LEU165F, LEU165H, LEU169F, LEU169H, LEU173F, LEU173H, LEU175H, LEU48F, LYS146H, LYS147H, LYS176F, LYS176H, LYS95F, MET104H, MET148H, PHE170F, PHE170H, PHE39F, PHE41F, PRO161F, PRO161H, THR153H, THR174H, THR96F, TYR168F, TYR168H, TYR40F, VAL46F, VAL51F