2FFL

crystal structure of dicer from giardia intestinalis

• Total interactions analyzed: 6
• Total true interactions: 3
• Strongest Interaction:
  • Chains: A-D
  • Int. Res.: 64
  • Norm. En. per Res.: -1.4401
• Hub Node: A(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-12.7181	61.0858	-190.273	-141.9053	165	10	1	9583	2	67	77
A-D	0.0	-27.1222	-65.0468	-92.169	64	2	2	3754	2	11	13
C-D	0.0	73.7794	-121.96	-48.1806	160	1	1	7323	2	68	77

Interface residues

• A-B: ALA358A, ALA358B, ALA389A, ALA397B, ALA403A, ALA403B, ARG372A, ARG372B, ARG484A, ARG484B, ARG492A, ARG492B, ARG494A, ARG494B, ARG678A, ARG678B, ARG680A, ARG680B, ASN373A, ASN373B, ASN377A, ASN377B, ASN393A, ASN393B, ASN394A, ASN394B, ASN686A, ASN686B, ASP340A, ASP340B, ASP357A, ASP357B, ASP404A, ASP404B, ASP495A, ASP495B, ASP653A, ASP653B, ASP714A, ASP714B, ASP720A, ASP720B, ASP753A, GLN381A, GLN381B, GLN387A, GLN387B, GLN548A, GLN646A, GLN646B, GLN681A, GLN681B, GLN712A, GLN712B, GLU336A, GLU336B, GLU365A, GLU365B, GLU369A, GLU369B, GLU374A, GLU374B, GLU390A, GLU407A, GLU407B, GLU491A, GLU491B, GLU547A, GLU547B, GLU649A, GLU649B, GLU673A, GLU684A, GLU684B, GLU723A, GLU723B, GLY361A, GLY361B, HIS643A, HIS643B, HIS708A, LEU306A, LEU363A, LEU363B, LEU366A, LEU366B, LEU376A, LEU376B, LEU395A, LEU395B, LEU650A, LEU650B, LYS367A, LYS367B, LYS398A, LYS398B, LYS400A, LYS400B, LYS438A, LYS438B, LYS647A, LYS647B, LYS657A, LYS657B, LYS716A, LYS716B, MET368A, MET368B, MET405A, MET488A, MET488B, PHE355A, PHE355B, PHE391A, PRO356A, PRO356B, PRO386A, PRO386B, PRO709B, SER359A, SER359B, SER392A, SER399A, SER399B, SER482A, SER482B, SER483A, SER483B, SER682A, SER682B, SER687A, SER687B, SER715A, SER715B, THR348A, THR362A, THR362B, THR401A, THR401B, THR487A, THR487B, THR677A, THR677B, THR685A, THR685B, TRP402A, TRP402B, TYR378A, TYR378B, TYR545A, TYR545B, TYR645A, TYR645B, VAL360A, VAL360B, VAL364A, VAL364B, VAL371A, VAL371B, VAL396B, VAL485A, VAL485B, VAL688B, VAL717A, VAL717B
• A-D: ALA443A, ALA612D, ALA621D, ALA740D, ARG535A, ARG618D, ARG695D, ARG743D, ASP446A, ASP528A, CYS444A, CYS456A, GLN614D, GLU435A, GLU702D, GLU744D, GLY516A, GLY519A, GLY521A, GLY522A, GLY607D, HIS513A, HIS532A, HIS610D, HIS745D, ILE509A, ILE527A, ILE611D, ILE624D, ILE629D, LEU517A, LEU620D, LYS284A, LYS438A, LYS453A, MET457A, PHE696D, PRO434A, PRO520A, PRO623D, PRO630D, PRO697D, PRO748D, SER433A, SER437A, SER515A, SER518A, SER525A, SER608D, SER617D, SER619D, SER626D, SER698D, THR382A, THR439A, THR449A, THR531A, THR615D, VAL523A, VAL524A, VAL616D, VAL622D, VAL699D, VAL700D
• C-D: ALA358C, ALA358D, ALA375C, ALA403C, ALA403D, ARG372C, ARG372D, ARG484C, ARG484D, ARG492C, ARG492D, ARG494C, ARG494D, ARG678C, ARG678D, ARG680C, ARG680D, ARG691C, ASN373C, ASN373D, ASN377C, ASN377D, ASN686C, ASN686D, ASP340C, ASP340D, ASP357C, ASP357D, ASP404C, ASP404D, ASP495C, ASP495D, ASP653C, ASP653D, ASP714C, ASP714D, ASP720C, ASP720D, ASP753C, ASP753D, CYS473D, GLN381C, GLN381D, GLN387D, GLN548C, GLN548D, GLN646C, GLN646D, GLN681C, GLN681D, GLN712C, GLN712D, GLU336C, GLU336D, GLU365C, GLU365D, GLU369C, GLU369D, GLU374C, GLU374D, GLU407C, GLU407D, GLU474D, GLU491C, GLU491D, GLU547C, GLU547D, GLU649C, GLU649D, GLU673C, GLU673D, GLU684C, GLU684D, GLU723C, GLU723D, GLY361C, GLY361D, HIS643C, HIS643D, HIS708C, HIS708D, LEU354C, LEU363C, LEU363D, LEU366C, LEU366D, LEU376C, LEU376D, LEU650C, LEU650D, LYS367C, LYS367D, LYS398C, LYS400C, LYS400D, LYS438C, LYS438D, LYS647C, LYS647D, LYS657C, LYS657D, LYS716C, LYS716D, MET368C, MET368D, MET488C, MET488D, PHE355C, PHE355D, PRO356C, PRO356D, PRO386C, PRO386D, PRO642C, PRO642D, PRO709C, PRO709D, SER359C, SER359D, SER399C, SER399D, SER482C, SER482D, SER483C, SER483D, SER486D, SER682C, SER682D, SER687C, SER687D, SER715C, SER715D, THR362C, THR362D, THR401C, THR401D, THR487C, THR487D, THR677C, THR677D, THR685C, THR685D, TRP402C, TRP402D, TYR378C, TYR378D, TYR545C, TYR545D, TYR645C, TYR645D, VAL360C, VAL360D, VAL364C, VAL364D, VAL371C, VAL371D, VAL485C, VAL485D, VAL717C, VAL717D