2FF6

crystal structure of gelsolin domain 1:ciboulot domain 2 hybrid in complex with actin

• Total interactions analyzed: 3
• Total true interactions: 3
• Strongest Interaction:
  • Chains: G-A
  • Int. Res.: 109
  • Norm. En. per Res.: -3.5252
• Hub Node: G(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
G-H	0.0	0.0	3.1092	3.1092	5	6	0	628	0	2	0
G-A	-69.8976	31.6766	-346.029	-384.2499	109	15	9	12757	2	22	18
H-A	-19.1957	-29.7925	-146.324	-195.3123	61	3	1	6300	1	20	28

Interface residues

• G-H: ASN155H, GLU153H, HIS151G, THR154H, VAL152G
• G-A: ALA100G, ALA101G, ALA102G, ALA116G, ALA144A, ALA22A, ALA26A, ALA295A, ALA29A, ALA347A, ARG115G, ARG120G, ARG147A, ARG28A, ARG335A, ASN296A, ASP109G, ASP110G, ASP24A, ASP25A, ASP292A, ASP50G, ASP96G, CYS93G, GLN107G, GLN118G, GLN353A, GLN354A, GLN95G, GLU121G, GLU167A, GLU28G, GLU31G, GLU334A, GLU47G, GLU97G, GLY114G, GLY146A, GLY148G, GLY168A, GLY20A, GLY23A, GLY342A, GLY343A, GLY99G, HIS119G, HIS151G, HIS29G, ILE103G, ILE165A, ILE330A, ILE341A, ILE345A, LEU104A, LEU108G, LEU140A, LEU142A, LEU33G, LEU346A, LEU349A, LEU51G, LEU85G, LEU89G, LYS150G, LYS326A, LYS328A, LYS48G, MET355A, PHE104G, PHE125G, PHE149G, PHE21A, PHE32G, PHE352A, PHE375A, PHE49G, PRO27A, PRO30G, PRO332A, PRO333A, SER141A, SER145A, SER147G, SER338A, SER344A, SER348A, SER350A, SER94G, SER98G, THR105G, THR148A, THR149A, THR351A, THR6A, TRP340A, TYR111G, TYR143A, TYR166A, TYR169A, TYR337A, TYR87G, VAL106G, VAL117G, VAL122G, VAL139A, VAL152G, VAL298A, VAL46G, VAL52G
• H-A: ALA19A, ALA204A, ALA26A, ALA29A, ARG206A, ARG210A, ARG28A, ARG62A, ASN155H, ASN158H, ASN92A, ASP162H, ASP211A, ASP244A, ASP24A, ASP25A, ASP56A, GLN246A, GLN59A, GLU153H, GLU156H, GLU205A, GLU207A, GLU214A, GLU241A, GLU57A, GLU93A, GLY15A, GLY245A, GLY55A, GLY63A, HIS88A, ILE208A, ILE212A, ILE34A, LEU160H, LEU16A, LEU242A, LEU94A, LYS157H, LYS163H, LYS18A, LYS215A, LYS336A, LYS61A, PHE31A, PRO159H, PRO161H, PRO243A, PRO27A, PRO32A, SER33A, SER60A, THR154H, THR203A, TYR240A, TYR337A, TYR69A, VAL17A, VAL209A, VAL30A