2FEN

3-carboxy-cis,cis-muconate lactonizing enzyme from agrobacterium radiobacter s2

• Total interactions analyzed: 66
• Total true interactions: 25
• Strongest Interaction:
  • Chains: I-J
  • Int. Res.: 237
  • Norm. En. per Res.: -4.7188
• Hub Node: E(4)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-172.9432	-189.6619	-730.073	-1092.6781	239	24	21	28482	13	56	63
A-D	-105.04	0.3232	-664.018	-768.7348	227	19	31	27712	0	36	41
A-C	-18.0129	-18.2426	-208.198	-244.4535	89	8	1	7592	2	5	11
B-D	-20.7894	-15.0483	-192.224	-228.0617	90	8	1	7267	2	4	11
B-C	-55.5434	14.7883	-663.355	-704.11	219	16	31	27000	0	29	32
D-C	-195.2736	-185.6789	-727.782	-1108.7345	241	32	21	28594	12	58	63
D-E	0.0	0.0	-0.0392	-0.0392	5	0	0	19	0	2	2
D-F	-4.518	-34.3756	-10.0094	-48.903	22	0	0	467	4	14	22
C-E	-8.7798	-12.166	-3.0766	-24.0224	14	1	0	213	1	5	5
C-F	-7.8549	-32.7431	-22.9907	-63.5887	29	0	0	874	3	19	16
E-F	-184.6545	-200.197	-709.116	-1093.9676	240	31	21	28211	14	57	64
E-H	-86.536	20.0141	-633.961	-700.4829	215	16	30	26399	0	30	34
E-G	-18.9471	-13.5044	-186.807	-219.2584	83	6	1	6839	2	4	10
E-J	-14.3117	-52.9818	-26.1643	-93.4578	25	2	0	1045	4	14	7
F-H	-21.4423	-23.9431	-193.346	-238.7314	87	4	1	7064	2	4	9
F-G	-43.0764	15.4819	-653.936	-681.5305	218	13	31	26940	0	30	36
H-G	-172.795	-186.7942	-710.129	-1069.7182	238	23	20	28427	13	54	63
H-J	-20.3869	-24.0173	-87.4286	-131.8329	123	7	1	5395	3	55	62
H-K	-15.9716	-69.6769	-35.6326	-121.2811	26	1	0	1297	7	14	9
I-J	-212.6248	-183.0565	-722.67	-1118.3513	237	24	20	28415	14	58	65
I-L	-60.1331	20.3877	-653.026	-692.7714	218	19	31	26730	0	29	34
I-K	-13.8292	-23.4042	-189.335	-226.5684	85	7	0	6926	2	4	9
J-L	-21.7235	-23.5166	-197.116	-242.3561	86	9	1	7244	2	4	9
J-K	-62.0561	20.4751	-630.001	-671.5821	217	12	31	26031	0	25	34
L-K	-185.6037	-188.4408	-716.975	-1091.0195	240	26	20	28407	15	54	62

Interface residues

• A-B: ALA158A, ALA158B, ALA159A, ALA159B, ALA165A, ALA165B, ALA168A, ALA168B, ALA169A, ALA169B, ALA173A, ALA173B, ALA197A, ALA197B, ALA198A, ALA198B, ALA235A, ALA235B, ALA238A, ALA238B, ALA256A, ALA256B, ALA292A, ALA292B, ALA296A, ALA296B, ALA301A, ALA301B, ALA315A, ALA315B, ARG155A, ARG155B, ARG167A, ARG167B, ARG177A, ARG177B, ARG181A, ARG181B, ARG224A, ARG224B, ARG231A, ARG231B, ARG293A, ARG293B, ARG312A, ARG312B, ASN188A, ASN229A, ASN229B, ASN239A, ASN239B, ASN295A, ASN295B, ASP166A, ASP166B, ASP232A, ASP232B, ASP254A, ASP254B, ASP79A, ASP79B, GLN109A, GLN109B, GLN157A, GLN157B, GLN226A, GLN226B, GLN230A, GLN230B, GLN253A, GLN253B, GLN298A, GLN298B, GLN304A, GLN304B, GLN308A, GLN308B, GLN310A, GLN310B, GLU202A, GLU202B, GLU236A, GLU236B, GLU260A, GLU260B, GLU309A, GLU309B, GLU311A, GLU311B, GLY152A, GLY152B, GLY161A, GLY161B, GLY170A, GLY170B, GLY189A, GLY189B, GLY195A, GLY195B, GLY196A, GLY196B, GLY199A, GLY199B, GLY233A, GLY233B, GLY246A, GLY246B, GLY249A, GLY249B, GLY252A, GLY252B, GLY314A, GLY314B, GLY316A, GLY316B, GLY80A, GLY80B, HIS178A, HIS178B, HIS228A, HIS228B, HIS303A, HIS303B, ILE112A, ILE112B, ILE160A, ILE160B, ILE162A, ILE162B, ILE172A, ILE172B, ILE234A, ILE234B, ILE255A, ILE255B, ILE261A, ILE261B, ILE299A, ILE299B, LEU150A, LEU150B, LEU175A, LEU175B, LEU180B, LEU201A, LEU201B, LEU240A, LEU240B, LEU241A, LEU241B, LEU243A, LEU243B, LEU248A, LEU248B, LEU257A, LEU257B, LEU288A, LEU288B, LEU291A, LEU291B, LEU302A, LEU302B, LEU306A, LEU306B, LEU319A, LEU319B, LYS203A, LYS203B, LYS250A, LYS250B, MET156A, MET156B, MET258A, MET258B, MET318A, MET318B, MET327A, MET327B, PHE185A, PHE185B, PHE237A, PHE237B, PHE251A, PHE251B, PHE294A, PHE294B, PRO174A, PRO174B, PRO225A, PRO225B, SER108A, SER108B, SER242A, SER242B, SER300A, SER300B, SER305A, SER305B, SER313A, SER313B, THR107A, THR107B, THR151A, THR151B, THR154A, THR154B, THR163A, THR163B, THR184A, THR184B, THR200A, THR200B, THR245A, THR245B, THR247A, THR247B, THR290A, THR290B, TRP171A, TRP171B, TRP227A, TRP227B, TRP317A, TRP317B, TRP321A, TRP321B, TYR153A, TYR153B, VAL244A, VAL244B, VAL289A, VAL289B, VAL297A, VAL297B, VAL307A, VAL307B, VAL81A, VAL81B, VAL82A
• A-D: ALA256A, ALA256D, ALA26A, ALA26D, ALA285A, ALA285D, ALA28A, ALA28D, ALA292A, ALA292D, ALA296A, ALA296D, ALA301A, ALA301D, ALA315A, ALA315D, ALA330A, ALA330D, ALA67A, ALA67D, ALA71A, ALA71D, ALA77A, ALA77D, ARG119A, ARG119D, ARG293A, ARG293D, ARG312A, ARG312D, ARG340A, ARG340D, ARG73A, ARG73D, ASN281A, ASN281D, ASN284A, ASN284D, ASN295A, ASN295D, ASP17A, ASP17D, ASP29A, ASP29D, ASP31A, ASP31D, ASP68A, ASP68D, ASP79A, ASP79D, GLN253A, GLN253D, GLN298A, GLN298D, GLN304A, GLN304D, GLN310A, GLN310D, GLN326A, GLN326D, GLN344A, GLN344D, GLU22A, GLU22D, GLU260A, GLU260D, GLU286A, GLU286D, GLU309A, GLU309D, GLU320A, GLU320D, GLU7A, GLU7D, GLU85A, GLU85D, GLY13A, GLY13D, GLY16A, GLY16D, GLY269A, GLY269D, GLY270A, GLY270D, GLY271A, GLY314A, GLY314D, GLY316A, GLY316D, GLY75A, GLY75D, GLY80A, GLY80D, HIS303A, HIS303D, HIS74A, HIS74D, HIS8A, HIS8D, ILE112A, ILE112D, ILE20A, ILE20D, ILE21A, ILE21D, ILE299A, ILE299D, ILE30A, ILE30D, LEU11A, LEU11D, LEU14A, LEU14D, LEU23A, LEU23D, LEU257A, LEU257D, LEU288A, LEU288D, LEU291A, LEU291D, LEU302A, LEU302D, LEU319A, LEU319D, LEU322A, LEU322D, LEU324A, LEU324D, LEU336D, LEU3A, LEU3D, LEU72A, LEU72D, LEU86A, LEU86D, LYS279A, LYS279D, LYS27A, LYS27D, LYS78A, LYS78D, MET156A, MET156D, MET318A, MET318D, MET327A, MET327D, MET33A, MET33D, MET69A, MET69D, PHE10A, PHE10D, PHE15A, PHE15D, PHE24A, PHE24D, PHE294A, PHE294D, PHE6A, PHE6D, PRO282A, PRO282D, PRO325A, PRO325D, PRO5A, PRO5D, PRO84A, PRO84D, PRO9A, PRO9D, SER108A, SER115A, SER115D, SER12A, SER12D, SER18A, SER18D, SER25A, SER25D, SER2A, SER2D, SER300A, SER300D, SER305A, SER305D, SER313A, SER313D, SER4A, SER4D, SER70A, SER70D, THR287A, THR287D, THR290A, THR290D, THR323A, THR323D, THR329A, THR329D, THR333A, THR333D, TRP317A, TRP317D, TRP321A, TRP321D, VAL283A, VAL283D, VAL289A, VAL289D, VAL297A, VAL297D, VAL307A, VAL307D, VAL328A, VAL328D, VAL337A, VAL337D, VAL76A, VAL76D, VAL81A, VAL81D, VAL82A, VAL82D, VAL83A, VAL83D
• A-C: ALA158A, ALA158C, ALA159C, ALA256A, ALA256C, ALA259A, ALA259C, ALA285A, ALA285C, ALA296A, ALA296C, ALA301A, ALA301C, ALA315A, ALA315C, ARG155A, ARG155C, ARG167A, ARG167C, ARG293A, ARG293C, ASN281A, ASN281C, ASN284A, ASN284C, ASP254A, GLN157A, GLN157C, GLN253A, GLN253C, GLN280A, GLN304A, GLN304C, GLU260A, GLU260C, GLU286A, GLU286C, GLY152A, GLY152C, GLY252A, GLY252C, GLY262A, GLY262C, HIS303A, ILE255A, ILE255C, ILE261A, ILE261C, ILE265A, ILE265C, LEU14A, LEU14C, LEU257A, LEU257C, LEU267A, LEU267C, LEU319A, LEU319C, LYS279A, MET156A, MET156C, MET258A, MET258C, PHE15A, PHE15C, PRO282A, PRO282C, SER300A, SER300C, SER305A, SER305C, THR151A, THR151C, THR154A, THR154C, THR287A, THR287C, THR290A, THR290C, TYR153A, TYR153C, VAL283A, VAL283C, VAL289A, VAL289C, VAL297A, VAL297C, VAL307A, VAL307C
• B-D: ALA158B, ALA158D, ALA159B, ALA256B, ALA256D, ALA259B, ALA259D, ALA285B, ALA285D, ALA296B, ALA296D, ALA301B, ALA301D, ALA315B, ALA315D, ARG155B, ARG155D, ARG167B, ARG167D, ARG293B, ARG293D, ASN281B, ASN281D, ASN284B, ASN284D, ASP254B, ASP254D, GLN157B, GLN157D, GLN253B, GLN253D, GLN280D, GLN304B, GLN304D, GLU260B, GLU260D, GLU286B, GLU286D, GLY152B, GLY152D, GLY252B, GLY252D, GLY262B, GLY262D, HIS303D, ILE255B, ILE255D, ILE261B, ILE261D, ILE265B, ILE265D, LEU14B, LEU14D, LEU257B, LEU257D, LEU267B, LEU267D, LEU319B, LEU319D, LYS279D, MET156B, MET156D, MET258B, MET258D, PHE15B, PHE15D, PRO282B, PRO282D, SER300B, SER300D, SER305B, SER305D, THR151B, THR151D, THR154B, THR154D, THR287B, THR287D, THR290B, THR290D, TYR153B, TYR153D, VAL283B, VAL283D, VAL289B, VAL289D, VAL297B, VAL297D, VAL307B, VAL307D
• B-C: ALA256B, ALA256C, ALA26B, ALA26C, ALA285B, ALA285C, ALA28B, ALA28C, ALA292B, ALA292C, ALA296B, ALA296C, ALA301B, ALA301C, ALA315B, ALA315C, ALA330B, ALA330C, ALA67B, ALA67C, ALA71B, ALA71C, ALA77B, ALA77C, ARG119B, ARG119C, ARG293B, ARG293C, ARG312B, ARG312C, ARG340B, ARG340C, ARG73B, ARG73C, ASN281B, ASN281C, ASN284B, ASN284C, ASN295B, ASN295C, ASP17B, ASP17C, ASP29B, ASP29C, ASP31B, ASP31C, ASP68B, ASP68C, ASP79B, ASP79C, GLN253B, GLN253C, GLN298B, GLN298C, GLN304B, GLN304C, GLN310B, GLN310C, GLN326B, GLN326C, GLN344B, GLN344C, GLU22B, GLU22C, GLU260B, GLU260C, GLU286B, GLU286C, GLU309B, GLU309C, GLU320B, GLU320C, GLU7B, GLU7C, GLU85B, GLU85C, GLY13B, GLY13C, GLY16B, GLY16C, GLY269B, GLY270B, GLY314B, GLY314C, GLY316B, GLY316C, GLY75B, GLY75C, GLY80B, GLY80C, HIS303B, HIS303C, HIS74B, HIS74C, HIS8B, HIS8C, ILE112B, ILE112C, ILE20B, ILE20C, ILE21B, ILE21C, ILE299B, ILE299C, ILE30B, ILE30C, LEU11B, LEU11C, LEU14B, LEU14C, LEU23B, LEU23C, LEU257B, LEU257C, LEU288B, LEU288C, LEU291B, LEU291C, LEU302B, LEU302C, LEU319B, LEU319C, LEU322B, LEU322C, LEU324B, LEU324C, LEU336C, LEU3B, LEU3C, LEU72B, LEU72C, LEU86B, LEU86C, LYS27B, LYS27C, LYS78B, LYS78C, MET156B, MET156C, MET318B, MET318C, MET327B, MET327C, MET33B, MET33C, MET69B, MET69C, PHE10B, PHE10C, PHE15B, PHE15C, PHE24B, PHE24C, PHE294B, PHE294C, PHE6B, PHE6C, PRO282B, PRO282C, PRO325B, PRO325C, PRO5B, PRO5C, PRO9B, PRO9C, SER115B, SER115C, SER12B, SER12C, SER18B, SER18C, SER25B, SER25C, SER2B, SER2C, SER300B, SER300C, SER305B, SER305C, SER313B, SER313C, SER4B, SER4C, SER70B, SER70C, THR287B, THR287C, THR290B, THR290C, THR323B, THR323C, THR329B, THR329C, THR333B, THR333C, TRP317B, TRP317C, TRP321B, TRP321C, VAL283B, VAL283C, VAL289B, VAL289C, VAL297B, VAL297C, VAL307B, VAL307C, VAL328B, VAL328C, VAL337B, VAL337C, VAL76B, VAL76C, VAL81B, VAL81C, VAL82B, VAL82C, VAL83B, VAL83C
• D-C: ALA158C, ALA158D, ALA159C, ALA159D, ALA165C, ALA165D, ALA168C, ALA168D, ALA169C, ALA169D, ALA173C, ALA173D, ALA197C, ALA197D, ALA198C, ALA198D, ALA235C, ALA235D, ALA238C, ALA238D, ALA256C, ALA256D, ALA259D, ALA292C, ALA292D, ALA296C, ALA296D, ALA301C, ALA301D, ALA315C, ALA315D, ARG155C, ARG155D, ARG167C, ARG167D, ARG177C, ARG177D, ARG181C, ARG181D, ARG224C, ARG224D, ARG231C, ARG231D, ARG293C, ARG293D, ARG312C, ARG312D, ASN188D, ASN229C, ASN229D, ASN239C, ASN239D, ASN295C, ASN295D, ASP166C, ASP166D, ASP232C, ASP232D, ASP254C, ASP254D, ASP79C, ASP79D, GLN109C, GLN109D, GLN157C, GLN157D, GLN226C, GLN226D, GLN230C, GLN230D, GLN253C, GLN253D, GLN298C, GLN298D, GLN304C, GLN304D, GLN308C, GLN308D, GLN310C, GLN310D, GLU202C, GLU202D, GLU236C, GLU236D, GLU260C, GLU260D, GLU309C, GLU309D, GLU311C, GLU311D, GLY152C, GLY152D, GLY161C, GLY161D, GLY170C, GLY170D, GLY189C, GLY189D, GLY195C, GLY195D, GLY196C, GLY196D, GLY199C, GLY199D, GLY233C, GLY233D, GLY246C, GLY246D, GLY249C, GLY249D, GLY252C, GLY252D, GLY314C, GLY314D, GLY316C, GLY316D, GLY80C, GLY80D, HIS178C, HIS178D, HIS228C, HIS228D, HIS303C, HIS303D, ILE112C, ILE112D, ILE160C, ILE160D, ILE162C, ILE162D, ILE172C, ILE172D, ILE234C, ILE234D, ILE255C, ILE255D, ILE261C, ILE261D, ILE299C, ILE299D, LEU150C, LEU150D, LEU175C, LEU175D, LEU180C, LEU201C, LEU201D, LEU240C, LEU240D, LEU241C, LEU241D, LEU243C, LEU243D, LEU248C, LEU248D, LEU257C, LEU257D, LEU288C, LEU288D, LEU291C, LEU291D, LEU302C, LEU302D, LEU306C, LEU306D, LEU319C, LEU319D, LYS203C, LYS203D, LYS250C, LYS250D, MET156C, MET156D, MET258C, MET258D, MET318C, MET318D, MET327C, MET327D, PHE185C, PHE185D, PHE237C, PHE237D, PHE251C, PHE251D, PHE294C, PHE294D, PRO174C, PRO174D, PRO225C, PRO225D, SER108C, SER108D, SER242C, SER242D, SER300C, SER300D, SER305C, SER305D, SER313C, SER313D, THR107C, THR107D, THR151C, THR151D, THR154C, THR154D, THR163C, THR163D, THR184C, THR184D, THR200C, THR200D, THR245C, THR245D, THR247C, THR247D, THR290C, THR290D, TRP171C, TRP171D, TRP227C, TRP227D, TRP317C, TRP317D, TRP321C, TRP321D, TYR153C, TYR153D, VAL244C, VAL244D, VAL289C, VAL289D, VAL297C, VAL297D, VAL307C, VAL307D, VAL81C, VAL81D, VAL82C, VAL82D
• D-E: ASN188E, GLN187E, HIS147D, LYS217E, SER143D
• D-F: ALA43D, ARG218D, ARG218F, ASP214D, ASP52F, ASP53F, GLN42D, GLN42F, GLU125D, GLU46D, GLU56D, GLU56F, GLY220D, LYS121D, LYS217D, LYS217F, MET122D, SER60F, SER63F, THR129D, VAL59D, VAL59F
• C-E: ALA208E, ALA210E, ALA213E, ARG212E, ARG224E, ASN207C, ASP206C, ASP206E, ASP223E, GLY205C, GLY209E, ILE49C, PRO225E, SER48C
• C-F: ALA142F, ALA165F, ALA213C, ALA43C, ALA45C, ALA47C, ALA51C, ARG144F, ARG218C, ASP136F, ASP140F, ASP214C, ASP52C, GLN42C, GLU176F, GLU44C, GLU46C, GLY139F, GLY146F, HIS147F, ILE135F, ILE49C, LEU141F, LYS217C, PHE50C, SER143F, SER48C, THR137F, THR163F
• E-F: ALA158E, ALA158F, ALA159E, ALA159F, ALA165E, ALA165F, ALA168E, ALA168F, ALA169E, ALA169F, ALA173E, ALA173F, ALA197E, ALA197F, ALA198E, ALA198F, ALA235E, ALA235F, ALA238E, ALA238F, ALA256E, ALA256F, ALA292E, ALA292F, ALA296E, ALA296F, ALA301E, ALA301F, ALA315E, ALA315F, ARG155E, ARG155F, ARG167E, ARG167F, ARG177E, ARG177F, ARG181E, ARG181F, ARG224E, ARG224F, ARG231E, ARG231F, ARG293E, ARG293F, ARG312E, ARG312F, ASN188E, ASN229E, ASN229F, ASN239E, ASN239F, ASN295E, ASN295F, ASP166E, ASP166F, ASP232E, ASP232F, ASP254E, ASP254F, ASP79E, ASP79F, GLN109E, GLN109F, GLN157E, GLN157F, GLN226E, GLN226F, GLN230E, GLN230F, GLN253E, GLN253F, GLN298E, GLN298F, GLN304E, GLN304F, GLN308E, GLN308F, GLN310E, GLN310F, GLU202E, GLU202F, GLU236E, GLU236F, GLU260E, GLU260F, GLU309E, GLU309F, GLU311E, GLU311F, GLY152E, GLY152F, GLY161E, GLY161F, GLY170E, GLY170F, GLY189E, GLY189F, GLY195E, GLY195F, GLY196E, GLY196F, GLY199E, GLY199F, GLY233E, GLY233F, GLY246E, GLY246F, GLY249E, GLY249F, GLY252E, GLY252F, GLY314E, GLY314F, GLY316E, GLY316F, GLY80E, GLY80F, HIS178E, HIS178F, HIS228E, HIS228F, HIS303E, HIS303F, ILE112E, ILE112F, ILE160E, ILE160F, ILE162E, ILE162F, ILE172E, ILE172F, ILE234E, ILE234F, ILE255E, ILE255F, ILE261E, ILE261F, ILE299E, ILE299F, LEU150E, LEU150F, LEU175E, LEU175F, LEU201E, LEU201F, LEU240E, LEU240F, LEU241E, LEU241F, LEU243E, LEU243F, LEU248E, LEU248F, LEU257E, LEU257F, LEU288E, LEU288F, LEU291E, LEU291F, LEU302E, LEU302F, LEU306E, LEU306F, LEU319E, LEU319F, LYS203E, LYS203F, LYS250E, LYS250F, MET156E, MET156F, MET258E, MET258F, MET318E, MET318F, MET327E, MET327F, PHE185E, PHE185F, PHE237E, PHE237F, PHE251E, PHE251F, PHE294E, PHE294F, PRO174E, PRO174F, PRO225E, PRO225F, PRO84F, SER108E, SER108F, SER242E, SER242F, SER300E, SER300F, SER305E, SER305F, SER313E, SER313F, THR107E, THR107F, THR151E, THR151F, THR154E, THR154F, THR163E, THR163F, THR184E, THR184F, THR200E, THR200F, THR245E, THR245F, THR247E, THR247F, THR290E, THR290F, TRP171E, TRP171F, TRP227E, TRP227F, TRP317E, TRP317F, TRP321E, TRP321F, TYR153E, TYR153F, VAL244E, VAL244F, VAL289E, VAL289F, VAL297E, VAL297F, VAL307E, VAL307F, VAL76F, VAL81E, VAL81F, VAL82F
• E-H: ALA256E, ALA256H, ALA26E, ALA26H, ALA285E, ALA285H, ALA28E, ALA28H, ALA292E, ALA292H, ALA296E, ALA296H, ALA301E, ALA301H, ALA315E, ALA315H, ALA330E, ALA330H, ALA67E, ALA67H, ALA71E, ALA71H, ALA77E, ALA77H, ARG119E, ARG119H, ARG293E, ARG293H, ARG312E, ARG312H, ARG340E, ARG340H, ARG73E, ARG73H, ASN281E, ASN281H, ASN284E, ASN284H, ASN295E, ASN295H, ASP17E, ASP17H, ASP29E, ASP29H, ASP31E, ASP31H, ASP68E, ASP68H, ASP79E, ASP79H, GLN253E, GLN253H, GLN298E, GLN298H, GLN304E, GLN304H, GLN310E, GLN310H, GLN326E, GLN326H, GLN344E, GLN344H, GLU22E, GLU22H, GLU260E, GLU260H, GLU286E, GLU286H, GLU309E, GLU309H, GLU320E, GLU320H, GLU7E, GLU7H, GLU85E, GLU85H, GLY13E, GLY13H, GLY16E, GLY16H, GLY252H, GLY314E, GLY314H, GLY316E, GLY316H, GLY75E, GLY75H, GLY80E, GLY80H, HIS303E, HIS303H, HIS74E, HIS74H, HIS8E, HIS8H, ILE112E, ILE112H, ILE20E, ILE20H, ILE21E, ILE21H, ILE299E, ILE299H, ILE30E, ILE30H, LEU11E, LEU11H, LEU14E, LEU14H, LEU23E, LEU23H, LEU257E, LEU257H, LEU288E, LEU288H, LEU291E, LEU291H, LEU302E, LEU302H, LEU319E, LEU319H, LEU322E, LEU322H, LEU324E, LEU324H, LEU3E, LEU3H, LEU72E, LEU72H, LEU86E, LEU86H, LYS27E, LYS27H, LYS78E, LYS78H, MET156H, MET318E, MET318H, MET327E, MET327H, MET33E, MET33H, MET69E, MET69H, PHE10E, PHE10H, PHE15E, PHE15H, PHE24E, PHE24H, PHE294E, PHE294H, PHE6E, PHE6H, PRO282E, PRO282H, PRO325E, PRO325H, PRO5E, PRO5H, PRO9E, PRO9H, SER115E, SER115H, SER12E, SER12H, SER18E, SER25E, SER25H, SER2E, SER2H, SER300E, SER300H, SER305E, SER305H, SER313E, SER313H, SER4E, SER4H, SER70E, SER70H, THR287E, THR287H, THR290E, THR290H, THR323E, THR323H, THR329E, THR329H, THR333E, THR333H, TRP317E, TRP317H, TRP321E, TRP321H, VAL283E, VAL283H, VAL289E, VAL289H, VAL297E, VAL297H, VAL307E, VAL307H, VAL328E, VAL328H, VAL337E, VAL337H, VAL76E, VAL76H, VAL81E, VAL81H, VAL82E, VAL82H, VAL83E, VAL83H
• E-G: ALA158E, ALA158G, ALA256E, ALA256G, ALA259E, ALA259G, ALA285E, ALA285G, ALA296E, ALA296G, ALA301E, ALA301G, ALA315E, ALA315G, ARG155E, ARG155G, ARG167E, ARG167G, ARG293E, ARG293G, ASN281E, ASN281G, ASN284E, ASN284G, ASP254G, GLN157E, GLN157G, GLN253E, GLN253G, GLN304E, GLN304G, GLU260E, GLU260G, GLU286E, GLU286G, GLY152E, GLY252E, GLY252G, GLY262E, GLY262G, HIS303E, ILE255E, ILE255G, ILE261E, ILE261G, ILE265E, ILE265G, LEU14E, LEU14G, LEU257E, LEU257G, LEU267E, LEU267G, LEU319E, LEU319G, MET156E, MET156G, MET258E, MET258G, PHE15E, PHE15G, PRO282E, PRO282G, SER300E, SER300G, SER305E, THR151G, THR154E, THR154G, THR287E, THR287G, THR290E, THR290G, TYR153E, TYR153G, VAL283E, VAL283G, VAL289E, VAL289G, VAL297E, VAL297G, VAL307E, VAL307G
• E-J: ALA45J, ALA47J, ALA51J, ALA55J, ALA67E, ALA71E, ALA77E, ARG218J, ARG73E, ASP52J, ASP53J, ASP68E, GLN42J, GLU44J, GLU46J, GLU56J, GLU64J, HIS74E, ILE49J, LEU72E, MET69E, PHE50J, PRO9E, SER48J, SER70E
• F-H: ALA158F, ALA158H, ALA256F, ALA256H, ALA259F, ALA259H, ALA285F, ALA285H, ALA296F, ALA296H, ALA301F, ALA301H, ALA315F, ALA315H, ARG155F, ARG155H, ARG167F, ARG167H, ARG293F, ARG293H, ASN281F, ASN281H, ASN284F, ASN284H, ASP254F, ASP254H, GLN157F, GLN157H, GLN253F, GLN253H, GLN304F, GLN304H, GLU260F, GLU260H, GLU286F, GLU286H, GLY152F, GLY152H, GLY252F, GLY252H, GLY262F, GLY262H, GLY270F, ILE255F, ILE255H, ILE261F, ILE261H, ILE265F, ILE265H, LEU14F, LEU14H, LEU257F, LEU257H, LEU267F, LEU267H, LEU319F, LEU319H, MET156F, MET156H, MET258F, MET258H, PHE15F, PHE15H, PRO282F, PRO282H, SER300F, SER300H, SER305F, SER305H, THR151F, THR151H, THR154F, THR154H, THR287F, THR287H, THR290F, THR290H, TYR153F, TYR153H, VAL283F, VAL283H, VAL289F, VAL289H, VAL297F, VAL297H, VAL307F, VAL307H
• F-G: ALA256F, ALA256G, ALA26F, ALA26G, ALA285F, ALA285G, ALA28F, ALA28G, ALA292F, ALA292G, ALA296F, ALA296G, ALA301F, ALA301G, ALA315F, ALA315G, ALA330F, ALA330G, ALA67F, ALA67G, ALA71F, ALA71G, ALA77F, ALA77G, ARG119F, ARG119G, ARG293F, ARG293G, ARG312F, ARG312G, ARG340F, ARG340G, ARG73F, ARG73G, ASN281F, ASN281G, ASN284F, ASN284G, ASN295F, ASN295G, ASP17F, ASP17G, ASP29F, ASP29G, ASP31F, ASP31G, ASP68F, ASP68G, ASP79F, ASP79G, GLN253F, GLN253G, GLN298F, GLN298G, GLN304F, GLN304G, GLN310F, GLN310G, GLN326F, GLN326G, GLN344F, GLN344G, GLU22F, GLU22G, GLU260F, GLU260G, GLU286F, GLU286G, GLU309F, GLU309G, GLU320F, GLU320G, GLU7F, GLU7G, GLU85F, GLU85G, GLY13F, GLY13G, GLY16F, GLY16G, GLY269F, GLY270F, GLY314F, GLY314G, GLY316F, GLY316G, GLY75F, GLY75G, GLY80F, GLY80G, HIS303F, HIS303G, HIS74F, HIS74G, HIS8F, HIS8G, ILE112F, ILE112G, ILE20F, ILE20G, ILE21F, ILE21G, ILE299F, ILE299G, ILE30F, ILE30G, LEU11F, LEU11G, LEU14F, LEU14G, LEU23F, LEU23G, LEU257F, LEU257G, LEU288F, LEU288G, LEU291F, LEU291G, LEU302F, LEU302G, LEU319F, LEU319G, LEU322F, LEU322G, LEU324F, LEU324G, LEU336F, LEU3F, LEU3G, LEU72F, LEU72G, LEU86F, LEU86G, LYS27F, LYS27G, LYS78F, LYS78G, MET156F, MET318F, MET318G, MET327F, MET327G, MET33F, MET33G, MET69F, MET69G, PHE10F, PHE10G, PHE15F, PHE15G, PHE24F, PHE24G, PHE294F, PHE294G, PHE6F, PHE6G, PRO282F, PRO282G, PRO325F, PRO325G, PRO5F, PRO5G, PRO9F, PRO9G, SER115F, SER115G, SER12F, SER12G, SER18F, SER25F, SER25G, SER268G, SER2F, SER2G, SER300F, SER300G, SER305F, SER305G, SER313F, SER313G, SER4F, SER4G, SER70F, SER70G, THR287F, THR287G, THR290F, THR290G, THR323F, THR323G, THR329F, THR329G, THR333F, THR333G, TRP317F, TRP317G, TRP321F, TRP321G, VAL283F, VAL283G, VAL289F, VAL289G, VAL297F, VAL297G, VAL307F, VAL307G, VAL328F, VAL328G, VAL337F, VAL337G, VAL76F, VAL76G, VAL81F, VAL81G, VAL82F, VAL82G, VAL83F, VAL83G
• H-G: ALA158G, ALA158H, ALA159G, ALA159H, ALA165G, ALA165H, ALA168G, ALA168H, ALA169G, ALA169H, ALA173G, ALA173H, ALA197G, ALA197H, ALA198G, ALA198H, ALA235G, ALA235H, ALA238G, ALA238H, ALA256G, ALA256H, ALA292G, ALA292H, ALA296G, ALA296H, ALA301G, ALA301H, ALA315G, ALA315H, ARG155G, ARG155H, ARG167G, ARG167H, ARG177G, ARG177H, ARG181G, ARG181H, ARG224G, ARG224H, ARG231G, ARG231H, ARG293G, ARG293H, ARG312G, ARG312H, ASN229G, ASN229H, ASN239G, ASN239H, ASN295G, ASN295H, ASP166G, ASP166H, ASP232G, ASP232H, ASP254G, ASP254H, ASP79G, ASP79H, GLN109G, GLN109H, GLN157G, GLN157H, GLN226G, GLN226H, GLN230G, GLN230H, GLN253G, GLN253H, GLN298G, GLN298H, GLN304G, GLN304H, GLN308G, GLN308H, GLN310G, GLN310H, GLU202G, GLU202H, GLU236G, GLU236H, GLU260G, GLU260H, GLU309G, GLU309H, GLU311G, GLU311H, GLY152G, GLY152H, GLY161G, GLY161H, GLY170G, GLY170H, GLY189G, GLY189H, GLY195G, GLY195H, GLY196G, GLY196H, GLY199G, GLY199H, GLY233G, GLY233H, GLY246G, GLY246H, GLY249G, GLY249H, GLY252G, GLY252H, GLY314G, GLY314H, GLY316G, GLY316H, GLY80G, GLY80H, HIS178G, HIS178H, HIS228G, HIS228H, HIS303G, HIS303H, ILE112G, ILE112H, ILE160G, ILE160H, ILE162G, ILE162H, ILE172G, ILE172H, ILE234G, ILE234H, ILE255G, ILE255H, ILE261G, ILE261H, ILE299G, ILE299H, LEU150G, LEU150H, LEU175G, LEU175H, LEU180G, LEU201G, LEU201H, LEU240G, LEU240H, LEU241G, LEU241H, LEU243G, LEU243H, LEU248G, LEU248H, LEU257G, LEU257H, LEU288G, LEU288H, LEU302G, LEU302H, LEU306G, LEU306H, LEU319G, LEU319H, LYS203G, LYS203H, LYS250G, LYS250H, MET156G, MET156H, MET258G, MET258H, MET318G, MET318H, MET327G, MET327H, PHE185G, PHE185H, PHE237G, PHE237H, PHE251G, PHE251H, PHE294G, PHE294H, PRO174G, PRO174H, PRO225G, PRO225H, SER108G, SER108H, SER242G, SER242H, SER300G, SER300H, SER305G, SER305H, SER313G, SER313H, THR107G, THR107H, THR151G, THR151H, THR154G, THR154H, THR163G, THR163H, THR184G, THR184H, THR200G, THR200H, THR245G, THR245H, THR247G, THR247H, THR290G, THR290H, TRP171G, TRP171H, TRP227G, TRP227H, TRP317G, TRP317H, TRP321G, TRP321H, TYR153G, TYR153H, VAL244G, VAL244H, VAL289G, VAL289H, VAL297G, VAL297H, VAL307G, VAL307H, VAL76H, VAL81G, VAL81H, VAL82G, VAL82H
• H-J: ALA124H, ALA128H, ALA128J, ALA186H, ALA186J, ALA216H, ALA216J, ALA26H, ALA26J, ALA28H, ALA28J, ALA32H, ALA39H, ALA39J, ALA66H, ALA66J, ALA67H, ALA67J, ARG130H, ARG130J, ARG218H, ARG218J, ARG340H, ARG340J, ARG35H, ARG35J, ASN188H, ASN188J, ASP136H, ASP136J, ASP17H, ASP17J, ASP214H, ASP214J, ASP31H, ASP31J, ASP52H, ASP52J, ASP68H, ASP68J, GLN187H, GLN187J, GLN42H, GLN42J, GLU125H, GLU125J, GLU183H, GLU183J, GLU19H, GLU19J, GLU22H, GLU22J, GLU339J, GLU46H, GLU46J, GLU56H, GLU56J, GLU64H, GLU64J, GLY132H, GLY132J, GLY13H, GLY13J, GLY16H, GLY16J, GLY220H, GLY220J, HIS133H, HIS133J, ILE126H, ILE126J, ILE20J, ILE21H, ILE21J, ILE30H, ILE30J, ILE34H, ILE34J, LEU118H, LEU219H, LEU219J, LEU221H, LEU221J, LEU23H, LEU23J, LEU336H, LEU336J, LEU62H, LEU62J, LEU72H, LYS121H, LYS121J, LYS217H, LYS217J, LYS27H, LYS27J, MET122H, MET122J, MET69H, MET69J, PHE10H, PHE10J, PHE65H, PHE65J, PRO9H, PRO9J, SER12H, SER12J, SER18H, SER18J, SER25H, SER25J, SER60J, SER63H, SER63J, SER70H, SER70J, THR129H, THR129J, THR38H, THR38J, VAL59H, VAL59J
• H-K: ALA43H, ALA45H, ALA47H, ALA51H, ALA55H, ALA71K, ALA77K, ARG218H, ARG73K, ASP214H, ASP52H, ASP53H, ASP68K, GLN42H, GLU44H, GLU46H, GLU64H, HIS74K, ILE49H, LEU72K, MET69K, PHE50H, PRO9K, SER48H, SER63H, SER70K
• I-J: ALA158I, ALA158J, ALA159I, ALA159J, ALA165I, ALA165J, ALA168I, ALA168J, ALA169I, ALA169J, ALA173I, ALA173J, ALA197I, ALA197J, ALA198I, ALA198J, ALA235I, ALA235J, ALA238I, ALA238J, ALA256I, ALA256J, ALA292I, ALA292J, ALA296I, ALA296J, ALA301I, ALA301J, ALA315I, ALA315J, ARG155I, ARG155J, ARG167I, ARG167J, ARG177I, ARG177J, ARG181I, ARG181J, ARG224I, ARG224J, ARG231I, ARG231J, ARG293I, ARG293J, ARG312I, ARG312J, ASN188I, ASN229I, ASN229J, ASN239I, ASN239J, ASN295I, ASN295J, ASP166I, ASP166J, ASP232I, ASP232J, ASP254I, ASP254J, ASP79I, ASP79J, GLN109I, GLN109J, GLN157I, GLN157J, GLN226I, GLN226J, GLN230I, GLN230J, GLN253I, GLN253J, GLN298I, GLN298J, GLN304I, GLN304J, GLN308I, GLN308J, GLN310I, GLN310J, GLU202I, GLU202J, GLU236I, GLU236J, GLU260I, GLU260J, GLU309I, GLU309J, GLU311I, GLU311J, GLY152I, GLY152J, GLY161I, GLY161J, GLY170I, GLY170J, GLY189I, GLY189J, GLY195I, GLY196I, GLY196J, GLY199I, GLY199J, GLY233I, GLY233J, GLY246I, GLY246J, GLY249I, GLY249J, GLY252I, GLY252J, GLY314I, GLY314J, GLY316I, GLY316J, GLY80I, GLY80J, HIS178I, HIS178J, HIS228I, HIS228J, HIS303I, HIS303J, ILE112I, ILE112J, ILE160I, ILE160J, ILE162I, ILE162J, ILE172I, ILE172J, ILE234I, ILE234J, ILE255I, ILE255J, ILE261I, ILE261J, ILE299I, ILE299J, LEU150I, LEU150J, LEU175I, LEU175J, LEU201I, LEU201J, LEU240I, LEU240J, LEU241I, LEU241J, LEU243I, LEU243J, LEU248I, LEU248J, LEU257I, LEU257J, LEU288I, LEU288J, LEU291I, LEU291J, LEU302I, LEU302J, LEU306I, LEU306J, LEU319I, LEU319J, LYS203I, LYS203J, LYS250I, LYS250J, MET156I, MET156J, MET258I, MET258J, MET318I, MET318J, MET327I, MET327J, PHE185I, PHE185J, PHE237I, PHE237J, PHE251I, PHE251J, PHE294I, PHE294J, PRO174I, PRO174J, PRO225I, PRO225J, SER108I, SER108J, SER242I, SER242J, SER300I, SER300J, SER305I, SER305J, SER313I, SER313J, THR107I, THR107J, THR151I, THR151J, THR154I, THR154J, THR163I, THR163J, THR184I, THR184J, THR200I, THR200J, THR245I, THR245J, THR247I, THR247J, THR290I, THR290J, TRP171I, TRP171J, TRP227I, TRP227J, TRP317I, TRP317J, TRP321I, TRP321J, TYR153I, TYR153J, VAL244I, VAL244J, VAL289I, VAL289J, VAL297I, VAL297J, VAL307I, VAL307J, VAL81I, VAL81J, VAL82I
• I-L: ALA256I, ALA256L, ALA26I, ALA26L, ALA285I, ALA285L, ALA28I, ALA28L, ALA292I, ALA292L, ALA296I, ALA296L, ALA301I, ALA301L, ALA315I, ALA315L, ALA330I, ALA330L, ALA67I, ALA67L, ALA71I, ALA71L, ALA77I, ALA77L, ARG119I, ARG119L, ARG293I, ARG293L, ARG312I, ARG312L, ARG340I, ARG340L, ARG73I, ARG73L, ASN281I, ASN281L, ASN284I, ASN284L, ASN295I, ASN295L, ASP17I, ASP17L, ASP29I, ASP29L, ASP31I, ASP31L, ASP68I, ASP68L, ASP79I, ASP79L, GLN253I, GLN253L, GLN298I, GLN298L, GLN304I, GLN304L, GLN310I, GLN310L, GLN326I, GLN326L, GLN344I, GLN344L, GLN89I, GLU22I, GLU22L, GLU260I, GLU260L, GLU286I, GLU286L, GLU309I, GLU309L, GLU320I, GLU320L, GLU7I, GLU7L, GLU85I, GLU85L, GLY13I, GLY13L, GLY16I, GLY16L, GLY314I, GLY314L, GLY316I, GLY316L, GLY75I, GLY75L, GLY80I, GLY80L, HIS303I, HIS303L, HIS74I, HIS74L, HIS8I, HIS8L, ILE112I, ILE112L, ILE20I, ILE20L, ILE21I, ILE21L, ILE299I, ILE299L, ILE30I, ILE30L, LEU11I, LEU11L, LEU14I, LEU14L, LEU23I, LEU23L, LEU257I, LEU257L, LEU288I, LEU288L, LEU291I, LEU291L, LEU302I, LEU302L, LEU319I, LEU319L, LEU322I, LEU322L, LEU324I, LEU324L, LEU3I, LEU3L, LEU72I, LEU72L, LEU86I, LEU86L, LYS27I, LYS27L, LYS78I, LYS78L, MET156I, MET156L, MET318I, MET318L, MET327I, MET327L, MET33I, MET33L, MET69I, MET69L, PHE10I, PHE10L, PHE15I, PHE15L, PHE24I, PHE24L, PHE294I, PHE294L, PHE6I, PHE6L, PRO282I, PRO282L, PRO325I, PRO325L, PRO5I, PRO5L, PRO9I, PRO9L, SER115I, SER115L, SER12I, SER12L, SER18I, SER18L, SER25I, SER25L, SER268I, SER2I, SER2L, SER300I, SER300L, SER305I, SER305L, SER313I, SER313L, SER4I, SER4L, SER70I, SER70L, THR287I, THR287L, THR290I, THR290L, THR323I, THR323L, THR329I, THR329L, THR333I, THR333L, TRP317I, TRP317L, TRP321I, TRP321L, VAL283I, VAL283L, VAL289I, VAL289L, VAL297I, VAL297L, VAL307I, VAL307L, VAL328I, VAL328L, VAL337I, VAL337L, VAL76I, VAL76L, VAL81I, VAL81L, VAL82I, VAL82L, VAL83I, VAL83L
• I-K: ALA158I, ALA158K, ALA256I, ALA256K, ALA259I, ALA259K, ALA285I, ALA285K, ALA296I, ALA296K, ALA301I, ALA301K, ALA315I, ALA315K, ARG155I, ARG155K, ARG167I, ARG167K, ARG293I, ARG293K, ASN281I, ASN281K, ASN284I, ASN284K, ASP254I, ASP254K, GLN157I, GLN157K, GLN253I, GLN253K, GLN304I, GLN304K, GLU260I, GLU260K, GLU286I, GLU286K, GLY152K, GLY252I, GLY252K, GLY262I, GLY262K, ILE255I, ILE255K, ILE261I, ILE261K, ILE265I, ILE265K, LEU14I, LEU14K, LEU257I, LEU257K, LEU267I, LEU267K, LEU319I, LEU319K, MET156I, MET156K, MET258I, MET258K, PHE15I, PHE15K, PRO282I, PRO282K, SER300I, SER300K, SER305I, SER305K, THR151I, THR151K, THR154I, THR154K, THR287I, THR287K, THR290I, THR290K, TYR153I, TYR153K, VAL283I, VAL283K, VAL289I, VAL289K, VAL297I, VAL297K, VAL307I, VAL307K
• J-L: ALA158J, ALA158L, ALA159J, ALA256J, ALA256L, ALA259J, ALA259L, ALA285J, ALA285L, ALA296J, ALA296L, ALA301J, ALA301L, ALA315J, ALA315L, ARG155J, ARG155L, ARG167J, ARG167L, ARG293J, ARG293L, ASN281J, ASN281L, ASN284J, ASN284L, ASP254J, ASP254L, GLN157J, GLN157L, GLN253J, GLN253L, GLN304J, GLN304L, GLU260J, GLU260L, GLU286J, GLU286L, GLY152J, GLY252J, GLY252L, GLY262J, GLY262L, ILE255J, ILE255L, ILE261J, ILE261L, ILE265J, ILE265L, LEU14J, LEU14L, LEU257J, LEU257L, LEU267J, LEU267L, LEU319J, LEU319L, MET156J, MET156L, MET258J, MET258L, PHE15J, PHE15L, PRO282J, PRO282L, SER300J, SER300L, SER305J, SER305L, THR151J, THR151L, THR154J, THR154L, THR287J, THR287L, THR290J, THR290L, TYR153J, TYR153L, VAL283J, VAL283L, VAL289J, VAL289L, VAL297J, VAL297L, VAL307J, VAL307L
• J-K: ALA256J, ALA256K, ALA26J, ALA26K, ALA285J, ALA285K, ALA28J, ALA28K, ALA292J, ALA292K, ALA296J, ALA296K, ALA301J, ALA301K, ALA315J, ALA315K, ALA330J, ALA330K, ALA67J, ALA67K, ALA71J, ALA71K, ALA77J, ALA77K, ARG119J, ARG119K, ARG293J, ARG293K, ARG312J, ARG312K, ARG340J, ARG340K, ARG73J, ARG73K, ASN281J, ASN281K, ASN284J, ASN284K, ASN295J, ASN295K, ASP17J, ASP17K, ASP29J, ASP29K, ASP31J, ASP31K, ASP68J, ASP68K, ASP79J, ASP79K, GLN253J, GLN253K, GLN298J, GLN298K, GLN304J, GLN304K, GLN310J, GLN310K, GLN326J, GLN326K, GLN344J, GLN344K, GLN89J, GLN89K, GLU22J, GLU22K, GLU260J, GLU260K, GLU286J, GLU286K, GLU309J, GLU309K, GLU320J, GLU320K, GLU7J, GLU7K, GLU85J, GLY13J, GLY13K, GLY16J, GLY16K, GLY269J, GLY270J, GLY314J, GLY314K, GLY316J, GLY316K, GLY75J, GLY75K, GLY80J, GLY80K, HIS303J, HIS303K, HIS74J, HIS74K, HIS8J, HIS8K, ILE112J, ILE112K, ILE20J, ILE20K, ILE21J, ILE21K, ILE299J, ILE299K, ILE30J, ILE30K, LEU11J, LEU11K, LEU14J, LEU14K, LEU23J, LEU23K, LEU257J, LEU257K, LEU288J, LEU288K, LEU291J, LEU291K, LEU302J, LEU302K, LEU319J, LEU319K, LEU322J, LEU322K, LEU324J, LEU324K, LEU3J, LEU3K, LEU72J, LEU72K, LEU86J, LEU86K, LYS27J, LYS27K, LYS78J, LYS78K, MET156K, MET318J, MET318K, MET327J, MET327K, MET33J, MET33K, MET69J, MET69K, PHE10J, PHE10K, PHE15J, PHE15K, PHE24J, PHE24K, PHE294J, PHE294K, PHE6J, PHE6K, PRO282J, PRO282K, PRO325J, PRO325K, PRO5J, PRO5K, PRO9J, PRO9K, SER115J, SER115K, SER12J, SER12K, SER18J, SER18K, SER25J, SER25K, SER268K, SER2J, SER300J, SER300K, SER305J, SER305K, SER313J, SER313K, SER4J, SER4K, SER70J, SER70K, THR287J, THR287K, THR290J, THR290K, THR323J, THR323K, THR329J, THR329K, THR333J, THR333K, TRP317J, TRP317K, TRP321J, TRP321K, VAL283J, VAL283K, VAL289J, VAL289K, VAL297J, VAL297K, VAL307J, VAL307K, VAL328J, VAL328K, VAL337J, VAL337K, VAL76J, VAL76K, VAL81J, VAL81K, VAL82J, VAL82K, VAL83K
• L-K: ALA158K, ALA158L, ALA159K, ALA159L, ALA165K, ALA165L, ALA168K, ALA168L, ALA169K, ALA169L, ALA173K, ALA173L, ALA197K, ALA197L, ALA198K, ALA198L, ALA235K, ALA235L, ALA238K, ALA238L, ALA256K, ALA256L, ALA292K, ALA292L, ALA296K, ALA296L, ALA301K, ALA301L, ALA315K, ALA315L, ARG155K, ARG155L, ARG167K, ARG167L, ARG177K, ARG177L, ARG181K, ARG181L, ARG224K, ARG224L, ARG231K, ARG231L, ARG293K, ARG293L, ARG312K, ARG312L, ASN188L, ASN229K, ASN229L, ASN239K, ASN239L, ASN295K, ASN295L, ASP166K, ASP166L, ASP232K, ASP232L, ASP254K, ASP254L, ASP79K, ASP79L, GLN109K, GLN109L, GLN157K, GLN157L, GLN226K, GLN226L, GLN230K, GLN230L, GLN253K, GLN253L, GLN298K, GLN298L, GLN304K, GLN304L, GLN308K, GLN308L, GLN310K, GLN310L, GLU202K, GLU202L, GLU236K, GLU236L, GLU260K, GLU260L, GLU309K, GLU309L, GLU311K, GLU311L, GLY152K, GLY152L, GLY161K, GLY161L, GLY170K, GLY170L, GLY189K, GLY189L, GLY195K, GLY195L, GLY196K, GLY196L, GLY199K, GLY199L, GLY233K, GLY233L, GLY246K, GLY246L, GLY249K, GLY249L, GLY252K, GLY252L, GLY314K, GLY314L, GLY316K, GLY316L, GLY80K, GLY80L, HIS178K, HIS178L, HIS228K, HIS228L, HIS303K, HIS303L, ILE112K, ILE112L, ILE160K, ILE160L, ILE162K, ILE162L, ILE172K, ILE172L, ILE234K, ILE234L, ILE255K, ILE255L, ILE261K, ILE261L, ILE299K, ILE299L, LEU150K, LEU150L, LEU175K, LEU175L, LEU180K, LEU201K, LEU201L, LEU240K, LEU240L, LEU241K, LEU241L, LEU243K, LEU243L, LEU248K, LEU248L, LEU257K, LEU257L, LEU288K, LEU288L, LEU291K, LEU291L, LEU302K, LEU302L, LEU306K, LEU306L, LEU319K, LEU319L, LYS203K, LYS203L, LYS250K, LYS250L, MET156K, MET156L, MET258K, MET258L, MET318K, MET318L, MET327K, MET327L, PHE185K, PHE185L, PHE237K, PHE237L, PHE251K, PHE251L, PHE294K, PHE294L, PRO174K, PRO174L, PRO225K, PRO225L, SER108K, SER108L, SER242K, SER242L, SER300K, SER300L, SER305K, SER305L, SER313K, SER313L, THR107K, THR107L, THR151K, THR151L, THR154K, THR154L, THR163K, THR163L, THR184K, THR184L, THR200K, THR200L, THR245K, THR245L, THR247K, THR247L, THR290K, THR290L, TRP171K, TRP171L, TRP227K, TRP227L, TRP317K, TRP317L, TRP321K, TRP321L, TYR153K, TYR153L, VAL244K, VAL244L, VAL289K, VAL289L, VAL297K, VAL297L, VAL307K, VAL307L, VAL76K, VAL81K, VAL81L, VAL82K