2FE8

sars coronavirus papain-like protease: structure of a viral deubiquitinating enzyme

• Total interactions analyzed: 3
• Total true interactions: 3
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 126
  • Norm. En. per Res.: -1.7189
• Hub Node: A(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-29.9824	31.0878	-217.687	-216.5817	126	7	0	8739	1	27	29
A-C	-55.466	40.0105	-178.459	-193.9145	121	10	0	7980	0	24	30
B-C	-32.2771	90.6796	-253.217	-194.8145	141	16	1	10748	0	28	37

Interface residues

• A-B: ALA130B, ALA247B, ALA69B, ARG167B, ARG184B, ARG229B, ARG285A, ARG66A, ARG66B, ARG83A, ASN110A, ASN129B, ASN157A, ASN157B, ASN268A, ASP109A, ASP230B, ASP287A, ASP41A, ASP62A, ASP62B, ASP63B, ASP77A, ASP77B, CYS225B, CYS227B, CYS271A, GLN175B, GLN233B, GLN270A, GLN30A, GLN31A, GLU162A, GLU168B, GLU204B, GLU251A, GLU264A, GLU68B, GLU71B, GLU78A, GLU78B, GLY161A, GLY210B, GLY228B, GLY267A, GLY272A, GLY299A, GLY29A, GLY33A, GLY82A, HIS172B, HIS176B, HIS18B, HIS273A, HIS290A, HIS74B, ILE223B, ILE45A, LEU163A, LEU186B, LEU200B, LEU217B, LEU59A, LEU65A, LEU65B, LEU76A, LEU76B, LEU81A, LYS158A, LYS196B, LYS298A, LYS44A, MET207B, MET209B, MET245B, MET294A, MET85A, PHE32A, PHE70B, PHE80A, PHE80B, PRO131B, PRO224B, PRO248B, PRO300A, PRO34A, PRO60A, PRO60B, SER222B, SER246B, SER61A, SER61B, SER67B, SER79A, SER79B, SER86A, THR159A, THR171B, THR198B, THR199B, THR201B, THR211B, THR266A, THR275A, THR27A, THR292A, THR35A, THR43A, THR64B, THR75B, TRP107A, TYR208B, TYR265A, TYR269A, TYR274A, TYR28A, TYR297A, TYR36A, TYR72B, TYR84A, VAL160A, VAL188B, VAL221B, VAL226B, VAL42A, VAL58A
• A-C: ALA205A, ALA231A, ALA250C, ARG167A, ARG184A, ARG229A, ARG285C, ARG66A, ARG66C, ARG83C, ASN110C, ASN157A, ASN157C, ASN187A, ASN268C, ASP109C, ASP287C, ASP41C, ASP62A, ASP62C, ASP63A, ASP77A, ASP77C, CYS193A, CYS225A, CYS227A, CYS271C, GLN175A, GLN233A, GLN270C, GLN30C, GLN31C, GLU162C, GLU204A, GLU251C, GLU264C, GLU71A, GLU78A, GLU78C, GLY161C, GLY164C, GLY202A, GLY210A, GLY228A, GLY267C, GLY272C, GLY299C, GLY29C, GLY33C, GLY82C, HIS273C, HIS290C, ILE223A, LEU163C, LEU186A, LEU200A, LEU217A, LEU235A, LEU59C, LEU65C, LEU76A, LEU76C, LEU81C, LYS158C, LYS196A, LYS298C, LYS44C, MET207A, MET209A, MET244A, MET245A, MET85C, PHE32C, PHE70A, PHE80A, PHE80C, PRO224A, PRO249C, PRO300C, PRO34C, PRO60A, PRO60C, SER222A, SER246A, SER61A, SER61C, SER67A, SER79A, SER79C, SER86C, THR159C, THR171A, THR197A, THR198A, THR199A, THR201A, THR211A, THR232A, THR266C, THR275C, THR43C, THR64A, THR75A, TRP107C, TYR208A, TYR234A, TYR265C, TYR269C, TYR28C, TYR297C, TYR36C, TYR84C, VAL160C, VAL185A, VAL188A, VAL189A, VAL203A, VAL206A, VAL221A, VAL226A, VAL58C
• B-C: ALA108B, ALA182C, ALA205C, ALA231C, ALA250B, ALA69C, ARG167C, ARG184C, ARG229C, ARG285B, ARG66B, ARG66C, ARG83B, ASN110B, ASN111B, ASN129C, ASN16C, ASN187C, ASN268B, ASP109B, ASP13C, ASP287B, ASP41B, ASP62B, ASP62C, ASP63C, ASP77B, ASP77C, CYS112B, CYS193C, CYS225C, CYS227C, CYS271B, GLN175C, GLN195C, GLN233C, GLN270B, GLN30B, GLN31B, GLU162B, GLU180C, GLU204C, GLU251B, GLU264B, GLU68C, GLU71C, GLU78B, GLU78C, GLY161B, GLY164B, GLY202C, GLY210C, GLY228C, GLY267B, GLY272B, GLY299B, GLY29B, GLY33B, GLY82B, HIS172C, HIS176C, HIS18C, HIS192C, HIS273B, HIS290B, HIS74C, HIS90B, ILE223C, ILE45B, LEU163B, LEU186C, LEU200C, LEU217C, LEU59B, LEU65C, LEU76C, LEU81B, LYS183C, LYS196C, LYS298B, LYS44B, MET207C, MET209C, MET245C, MET26B, MET85B, PHE32B, PHE70C, PHE80B, PHE80C, PRO131C, PRO224C, PRO248B, PRO249B, PRO300B, PRO34B, PRO60B, PRO60C, SER246C, SER61B, SER61C, SER67C, SER79B, SER79C, SER86B, THR159B, THR15C, THR171C, THR197C, THR198C, THR199C, THR201C, THR211C, THR266B, THR275B, THR27B, THR302B, THR35B, THR43B, THR64C, THR75C, TRP107B, TYR208C, TYR234C, TYR252B, TYR265B, TYR269B, TYR274B, TYR28B, TYR297B, TYR36B, TYR72C, TYR84B, VAL160B, VAL188C, VAL203C, VAL221C, VAL226C, VAL301B, VAL42B, VAL58B