2F8V

structure of full length telethonin in complex with the n-terminus of titin

• Total interactions analyzed: 15
• Total true interactions: 9
• Strongest Interaction:
  • Chains: B-T
  • Int. Res.: 173
  • Norm. En. per Res.: -4.8436
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	0.0	0.0	-2.5121	-2.5121	13	0	0	217	0	0	0
A-T	-162.64	-41.1778	-402.869	-606.6868	155	22	8	16108	1	24	23
A-D	0.0	41.5645	-74.4561	-32.8916	54	5	3	3132	0	6	9
B-T	-248.3212	-77.9811	-511.641	-837.9433	173	41	11	19903	4	28	21
B-D	0.0	0.0	-0.0042	-0.0042	4	0	0	5	0	1	1
T-D	-44.8139	-2.5193	-43.532	-90.8652	25	6	0	1797	0	3	3
C-D	0.0	0.0	-2.4218	-2.4218	15	0	0	223	0	0	0
C-Y	-152.2732	-50.6277	-367.266	-570.1669	152	23	7	15062	2	24	20
D-Y	-206.9804	-88.7553	-476.834	-772.5697	176	52	12	20195	3	29	21

Interface residues

• A-B: ALA89A, ALA89B, ARG109A, ARG109B, ASN105B, PHE8A, PHE8B, PRO11A, PRO6A, PRO6B, THR7A, THR7B, THR9A
• A-T: ALA102A, ALA178A, ALA185A, ALA189A, ALA20T, ALA23T, ALA2T, ALA5A, ALA82A, ALA89A, ALA93A, ALA99A, ARG109A, ARG126A, ARG17T, ARG184A, ARG18T, ARG33T, ARG47T, ARG63T, ARG70T, ARG76T, ARG77A, ASN105A, ASN14T, ASN177A, ASN180A, ASN84A, ASP27T, ASP44T, GLN108A, GLN10A, GLN111A, GLN13A, GLN46T, GLN4A, GLN53T, GLN54T, GLN56T, GLN58T, GLN62T, GLN88A, GLU100A, GLU12T, GLU13T, GLU16T, GLU190A, GLU19T, GLU24T, GLU35T, GLU36T, GLU42T, GLU43T, GLU49T, GLU5T, GLU80T, GLU94A, GLU9T, GLY183A, GLY55T, GLY75T, GLY76A, GLY85A, GLY87A, HIS41T, HIS48T, HIS52T, ILE29A, LEU110A, LEU12A, LEU18A, LEU191A, LEU192A, LEU28T, LEU30T, LEU40T, LEU60T, LEU67T, LEU6T, LEU74T, LEU78T, LEU80A, LEU95A, LEU96A, LYS26T, LYS81A, LYS98A, MET113A, MET1T, MET68T, MET69T, PHE106A, PHE21T, PHE25A, PHE8A, PRO103A, PRO104A, PRO11A, PRO34T, PRO65T, PRO6A, SER112A, SER11T, SER14A, SER15T, SER175A, SER181A, SER187A, SER30A, SER38T, SER39T, SER4T, SER57T, SER64T, SER75A, SER79A, SER7T, SER86A, SER8T, SER91A, THR101A, THR114A, THR173A, THR179A, THR186A, THR188A, THR29T, THR2A, THR32T, THR3A, THR3T, THR50T, THR7A, THR83A, THR90A, THR92A, THR9A, TRP22T, TRP25T, TRP66T, TYR174A, TYR51T, TYR78A, VAL107A, VAL10T, VAL125A, VAL127A, VAL15A, VAL16A, VAL176A, VAL17A, VAL182A, VAL59T, VAL61T, VAL97A
• A-D: ALA102A, ALA164D, ALA166D, ALA23A, ALA69A, ARG122D, ARG126A, ARG126D, ASN105A, ASP149D, ASP157A, ASP157D, GLN108A, GLN120D, GLN124D, GLN151D, GLN154D, GLU100A, GLU155D, GLU165D, GLU169D, GLU19A, GLY118D, GLY129A, GLY156A, GLY156D, GLY20A, ILE130A, ILE163D, LEU148D, LEU158A, LEU158D, LEU162D, LEU18A, LYS64A, LYS98A, PRO103A, PRO68A, SER119D, SER147D, SER153D, SER21A, THR101A, THR128A, THR22A, THR24A, THR71A, TYR167D, VAL107A, VAL127A, VAL15A, VAL16A, VAL17A, VAL70A
• B-T: ALA102B, ALA178B, ALA185B, ALA189B, ALA20T, ALA23B, ALA23T, ALA27B, ALA5B, ALA69B, ALA82B, ALA89B, ALA93B, ALA99B, ARG109B, ARG17T, ARG184B, ARG18T, ARG33T, ARG47T, ARG63T, ARG70T, ARG76T, ARG77B, ARG87T, ASN105B, ASN14T, ASN177B, ASN180B, ASN84B, ASP27T, ASP44T, GLN108B, GLN10B, GLN111B, GLN13B, GLN46T, GLN4B, GLN53T, GLN54T, GLN56T, GLN58T, GLN62T, GLN79T, GLN82T, GLN86T, GLN88B, GLU100B, GLU12T, GLU13T, GLU16T, GLU190B, GLU19B, GLU19T, GLU24T, GLU35T, GLU36T, GLU42T, GLU43T, GLU49T, GLU5T, GLU80T, GLU94B, GLU9T, GLY129B, GLY183B, GLY20B, GLY37T, GLY55T, GLY72T, GLY76B, GLY77T, GLY85B, GLY87B, HIS41T, HIS48T, HIS52T, ILE130B, ILE29B, ILE67B, ILE73T, LEU110B, LEU12B, LEU18B, LEU191B, LEU192B, LEU40T, LEU60T, LEU67T, LEU74T, LEU78T, LEU80B, LEU83T, LEU95B, LEU96B, LYS26T, LYS81B, LYS98B, MET113B, MET68T, MET69T, MET71T, PHE106B, PHE21T, PHE32B, PHE8B, PRO103B, PRO104B, PRO11B, PRO33B, PRO34T, PRO65T, PRO68B, PRO6B, PRO84T, SER112B, SER11T, SER14B, SER175B, SER181B, SER187B, SER21B, SER30B, SER31T, SER38T, SER39T, SER57T, SER64T, SER75B, SER79B, SER86B, SER8T, SER91B, THR101B, THR114B, THR128B, THR173B, THR179B, THR186B, THR188B, THR22B, THR29T, THR2B, THR32T, THR3B, THR3T, THR45T, THR50T, THR7B, THR83B, THR90B, THR92B, THR9B, TRP22T, TRP25T, TRP66T, TYR174B, TYR51T, TYR78B, TYR81T, TYR85T, VAL107B, VAL10T, VAL127B, VAL15B, VAL16B, VAL176B, VAL17B, VAL182B, VAL59T, VAL61T, VAL70B, VAL97B
• B-D: GLN10B, GLN13B, MET113D, SER119D
• T-D: ALA164D, ALA166D, ARG116D, ARG122D, ARG70T, ARG76T, GLN117D, GLN120D, GLN79T, GLU165D, GLU80T, GLY118D, GLY75T, GLY77T, ILE163D, ILE73T, LEU162D, LEU60T, LEU74T, LEU78T, SER119D, TYR167D, TYR81T, VAL115D, VAL121D
• C-D: ALA89C, ALA89D, ARG109C, ARG109D, ASN105C, ASN105D, PHE8C, PHE8D, PRO11C, PRO11D, PRO6C, PRO6D, THR7C, THR7D, THR9C
• C-Y: ALA102C, ALA178C, ALA185C, ALA189C, ALA20Y, ALA23Y, ALA2Y, ALA5C, ALA82C, ALA89C, ALA93C, ALA99C, ARG109C, ARG126C, ARG17Y, ARG184C, ARG18Y, ARG33Y, ARG47Y, ARG63Y, ARG70Y, ARG76Y, ARG77C, ASN105C, ASN14Y, ASN177C, ASN180C, ASN84C, ASP27Y, ASP44Y, GLN108C, GLN10C, GLN111C, GLN13C, GLN46Y, GLN4C, GLN53Y, GLN54Y, GLN56Y, GLN58Y, GLN62Y, GLN88C, GLU100C, GLU12Y, GLU13Y, GLU16Y, GLU190C, GLU19Y, GLU24Y, GLU26C, GLU35Y, GLU36Y, GLU42Y, GLU43Y, GLU49Y, GLU5Y, GLU80Y, GLU94C, GLU9Y, GLY183C, GLY55Y, GLY75Y, GLY76C, GLY85C, GLY87C, HIS28C, HIS41Y, HIS48Y, HIS52Y, ILE29C, ILE73Y, LEU110C, LEU12C, LEU18C, LEU191C, LEU192C, LEU28Y, LEU30Y, LEU40Y, LEU60Y, LEU6Y, LEU74Y, LEU78Y, LEU80C, LEU95C, LEU96C, LYS26Y, LYS81C, LYS98C, MET113C, MET1Y, MET68Y, MET69Y, PHE106C, PHE21Y, PHE25C, PHE8C, PRO103C, PRO104C, PRO11C, PRO65Y, PRO6C, SER112C, SER11Y, SER14C, SER15Y, SER175C, SER181C, SER187C, SER30C, SER38Y, SER39Y, SER4Y, SER57Y, SER64Y, SER75C, SER79C, SER7Y, SER86C, SER8Y, SER91C, THR101C, THR114C, THR128C, THR173C, THR179C, THR186C, THR188C, THR29Y, THR32Y, THR50Y, THR7C, THR83C, THR90C, THR92C, THR9C, TRP22Y, TRP25Y, TRP66Y, TYR174C, TYR51Y, TYR78C, VAL107C, VAL10Y, VAL125C, VAL127C, VAL15C, VAL16C, VAL176C, VAL17C, VAL182C, VAL97C
• D-Y: ALA102D, ALA178D, ALA185D, ALA189D, ALA20Y, ALA23D, ALA23Y, ALA27D, ALA5D, ALA69D, ALA82D, ALA89D, ALA93D, ALA99D, ARG109D, ARG126D, ARG17Y, ARG184D, ARG18Y, ARG33Y, ARG47Y, ARG63Y, ARG70Y, ARG76Y, ARG77D, ARG87Y, ASN105D, ASN14Y, ASN177D, ASN180D, ASN84D, ASP27Y, ASP44Y, GLN108D, GLN10D, GLN111D, GLN13D, GLN46Y, GLN4D, GLN53Y, GLN54Y, GLN56Y, GLN58Y, GLN62Y, GLN79Y, GLN82Y, GLN86Y, GLN88D, GLU100D, GLU12Y, GLU13Y, GLU16Y, GLU190D, GLU19D, GLU19Y, GLU24Y, GLU26D, GLU35Y, GLU36Y, GLU42Y, GLU43Y, GLU49Y, GLU5Y, GLU80Y, GLU94D, GLU9Y, GLY129D, GLY183D, GLY20D, GLY37Y, GLY55Y, GLY72Y, GLY76D, GLY77Y, GLY85D, GLY87D, HIS41Y, HIS48Y, HIS52Y, ILE130D, ILE29D, ILE73Y, LEU110D, LEU12D, LEU18D, LEU191D, LEU40Y, LEU60Y, LEU67Y, LEU74Y, LEU78Y, LEU80D, LEU83Y, LEU95D, LEU96D, LYS26Y, LYS81D, LYS98D, MET113D, MET68Y, MET69Y, MET71Y, PHE106D, PHE21Y, PHE25D, PHE32D, PHE8D, PRO103D, PRO104D, PRO11D, PRO131D, PRO33D, PRO34Y, PRO65Y, PRO68D, PRO6D, PRO84Y, SER112D, SER11Y, SER14D, SER175D, SER181D, SER187D, SER21D, SER30D, SER31Y, SER38Y, SER39Y, SER57Y, SER64Y, SER75D, SER79D, SER7Y, SER86D, SER8Y, SER91D, THR101D, THR114D, THR128D, THR173D, THR179D, THR186D, THR188D, THR22D, THR29Y, THR2D, THR32Y, THR3D, THR3Y, THR45Y, THR50Y, THR7D, THR90D, THR92D, THR9D, TRP22Y, TRP25Y, TRP66Y, TYR174D, TYR51Y, TYR78D, TYR81Y, TYR85Y, VAL107D, VAL10Y, VAL127D, VAL15D, VAL16D, VAL176D, VAL17D, VAL182D, VAL59Y, VAL61Y, VAL70D, VAL88Y, VAL97D