2F6J

crystal structure of phd finger-linker-bromodomain fragment of human bptf in the h3(1-15)k4me3 bound state

• Total interactions analyzed: 6
• Total true interactions: 3
• Strongest Interaction:
  • Chains: A-P
  • Int. Res.: 35
  • Norm. En. per Res.: -4.6958
• Hub Node: A(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	0.0	-10.4008	-1.4295	-11.8303	6	0	0	165	0	3	5
A-P	-39.1185	-25.2225	-100.012	-164.353	35	3	4	3655	1	5	2
B-C	-45.4312	-28.0395	-112.337	-185.8077	40	10	1	4622	0	12	14

Interface residues

• A-B: ARG28B, ASP27B, GLN30B, GLU50B, GLY107A, LYS110A
• A-P: ALA1P, ALA45A, ARG28A, ARG2P, ASN31A, ASP18A, ASP27A, ASP49A, CYS26A, CYS29A, GLN30A, GLN42A, GLN5P, GLU19A, GLU44A, GLU46A, GLU50A, GLY25A, GLY35A, ILE24A, ILE40A, ILE48A, LEU41A, LEU47A, LYS21A, PHE22A, SER20A, THR3P, THR6P, TRP32A, TYR17A, TYR23A, TYR33A, TYR51A, VAL52A
• B-C: ALA45B, ALA45C, ARG36B, ARG36C, ASP18B, ASP18C, CYS37B, CYS37C, GLN42B, GLN42C, GLU19B, GLU19C, GLU44B, GLU44C, GLU46B, GLU46C, GLY35B, GLY35C, GLY39B, HIS34B, HIS34C, ILE24C, ILE40B, ILE40C, LEU41B, LEU41C, LYS21B, LYS21C, PHE22B, PHE22C, SER20B, SER20C, SER43B, SER43C, TRP32B, TRP32C, TYR17B, TYR17C, TYR23B, TYR23C