2F5B

crystal structure of fab' from the hiv-1 neutralizing antibody 2f5 in complex with its gp41 epitope

• Total interactions analyzed: 3
• Total true interactions: 3
• Strongest Interaction:
  • Chains: L-P
  • Int. Res.: 19
  • Norm. En. per Res.: -7.4644
• Hub Node: L(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
L-H	-29.1709	2.7892	-511.802	-538.1837	199	23	15	19993	4	27	22
L-P	-36.3876	-21.1391	-84.2963	-141.8231	19	6	1	2583	1	5	3
H-P	-29.2066	-32.9451	-95.13	-157.2816	36	3	0	3354	8	11	9

Interface residues

• L-H: ALA112H, ALA118H, ALA130L, ALA144H, ALA154H, ALA155H, ALA156H, ALA187H, ALA1L, ALA32L, ALA34L, ALA46H, ALA51H, ALA51L, ALA98H, ARG100H, ARG101H, ARG103L, ARG113H, ARG142L, ARG37L, ARG40H, ARG60H, ASN117H, ASN137L, ASN138L, ASP120H, ASP122L, ASP163H, ASP167L, ASP170L, ASP50L, ASP58H, CYS134L, CYS159H, CYS214L, CYS88L, CYS97H, GLN124H, GLN124L, GLN160L, GLN166L, GLN190H, GLN38L, GLN41H, GLN45L, GLN6L, GLN89L, GLN90L, GLU123L, GLU161L, GLU165L, GLU48H, GLU55L, GLU6H, GLY100L, GLY101L, GLY114H, GLY123H, GLY125H, GLY153H, GLY157L, GLY158H, GLY181H, GLY193H, GLY35H, GLY37H, GLY41L, GLY44H, GLY99L, HIS183H, HIS92L, HIS96L, HIS99H, ILE117L, ILE39H, ILE48L, ILE52H, ILE53H, LEU125L, LEU135L, LEU136L, LEU143H, LEU157H, LEU160H, LEU175L, LEU179L, LEU181L, LEU189H, LEU194H, LEU197H, LEU208H, LEU2L, LEU33L, LEU46L, LEU47H, LEU47L, LEU50H, LEU54L, LEU65H, LEU91L, LYS126L, LYS136H, LYS162H, LYS169L, LYS228H, LYS233H, LYS39L, LYS45H, LYS59H, MET119H, PHE116L, PHE118L, PHE139L, PHE141H, PHE185H, PHE93L, PHE96H, PHE98L, PRO115H, PRO119L, PRO120L, PRO142H, PRO145H, PRO186H, PRO232H, PRO40L, PRO42H, PRO43L, PRO44L, PRO63H, PRO95L, SER114L, SER121L, SER127L, SER131L, SER139H, SER146H, SER159L, SER162L, SER168L, SER174L, SER176L, SER177L, SER180H, SER191H, SER192H, SER196H, SER198H, SER199H, SER205H, SER234H, SER31L, SER42L, SER52L, SER53L, SER56L, SER62H, SER64H, THR129L, THR164L, THR172L, THR178L, THR180L, THR184H, THR202H, THR30L, THR85L, THR94H, THR97L, TRP122H, TRP35L, TRP38H, TRP49H, TYR173L, TYR195H, TYR36L, TYR49L, TYR54H, TYR61H, TYR86L, TYR87L, TYR94L, VAL115L, VAL116H, VAL121H, VAL132L, VAL133L, VAL140H, VAL161H, VAL163L, VAL182H, VAL188H, VAL200H, VAL201H, VAL203H, VAL226H, VAL230H, VAL29L
• L-P: ALA32L, ALA6P, ASP3P, GLN90L, GLU1P, GLY28L, HIS92L, HIS96L, LEU2L, LEU2P, LEU91L, LYS4P, PHE93L, PRO95L, SER7P, THR30L, TRP5P, TYR94L, VAL29L
• H-P: ALA112H, ALA118H, ALA6P, ARG100H, ARG101H, ARG113H, ARG60H, ASN117H, ASP31H, ASP3P, ASP56H, ASP57H, ASP58H, GLU1P, GLY102H, GLY114H, GLY33H, GLY35H, ILE52H, ILE53H, LEU2P, LYS4P, LYS59H, MET119H, PHE32H, PRO103H, PRO110H, PRO63H, SER55H, SER7P, TRP49H, TRP5P, TYR54H, TYR61H, VAL116H, VAL34H