2EK6

crystal structure of human rna-binding protein 12

• Total interactions analyzed: 6
• Total true interactions: 6
• Strongest Interaction:
  • Chains: A-D
  • Int. Res.: 40
  • Norm. En. per Res.: -3.2506
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-45.8248	14.6067	514.638	483.4199	62	22	6	6903	0	9	9
A-C	0.0	21.5284	-1.2661	20.2623	4	0	0	36	0	0	5
A-D	-21.564	-16.664	-91.7965	-130.0245	40	10	1	3694	2	5	5
B-C	-8.299	-11.2255	-84.0911	-103.6156	37	1	1	3332	1	5	5
B-D	-7.5248	40.2787	-70.91	-38.1561	40	3	0	2812	0	3	10
C-D	-37.4081	4.5318	517.605	484.7287	60	16	5	6264	0	9	10

Interface residues

• A-B: ALA58A, ALA58B, ALA61A, ALA61B, ASN49A, ASN49B, ASP28A, ASP28B, ASP32B, CYS45A, CYS45B, GLU29B, GLU50A, GLU50B, GLU57A, GLU57B, GLY42A, GLY42B, GLY52A, GLY52B, ILE16B, ILE27A, ILE27B, ILE30A, ILE30B, ILE40A, ILE40B, LEU31A, LEU31B, LEU46A, LEU46B, LYS17A, LYS17B, LYS47A, LYS47B, LYS51A, LYS51B, MET53A, MET53B, MET59A, MET59B, PRO13B, PRO41A, PRO41B, PRO54A, PRO54B, SER26A, SER26B, SER43A, SER43B, THR55A, THR55B, TYR48A, TYR48B, VAL15A, VAL15B, VAL25A, VAL25B, VAL44A, VAL44B, VAL60A, VAL60B
• A-C: ASP28A, ASP28C, ILE27A, ILE27C
• A-D: ARG83D, ASN20D, ASN49A, ASN49D, ASP28A, GLU29A, GLU50A, GLU50D, GLY52A, GLY52D, GLY56D, GLY81A, GLY81D, ILE27A, ILE30A, ILE80A, ILE80D, LEU46A, LYS47A, LYS51A, LYS51D, MET21A, MET21D, MET53A, MET53D, PHE23A, PHE23D, PRO22A, PRO22D, PRO54A, PRO54D, SER26A, SER82D, THR24A, THR24D, THR55D, TYR48A, VAL25A, VAL25D, VAL44A
• B-C: ARG83B, ASN49B, ASN49C, ASP28C, GLU29C, GLU50B, GLU50C, GLY52B, GLY52C, GLY81B, GLY81C, ILE27C, ILE30C, ILE80B, ILE80C, LEU46C, LYS47C, LYS51B, LYS51C, MET21B, MET53B, MET53C, PHE23B, PHE23C, PRO22B, PRO22C, PRO54B, PRO54C, SER26C, SER82B, THR24B, THR24C, THR55B, TYR48C, VAL25B, VAL25C, VAL44C
• B-D: ASP28B, ASP28D, ASP32B, CYS45D, GLU29B, GLU29D, GLY52B, GLY52D, GLY81B, GLY81D, ILE27B, ILE27D, ILE30B, ILE30D, ILE80B, ILE80D, LEU46B, LEU46D, LYS51B, LYS51D, MET53B, MET53D, PHE23B, PHE23D, PRO22B, PRO22D, PRO54B, PRO54D, SER26B, SER26D, SER82B, SER82D, THR24B, THR24D, TYR48B, TYR48D, VAL25B, VAL25D, VAL44B, VAL44D
• C-D: ALA58C, ALA58D, ALA61C, ALA61D, ASN49C, ASN49D, ASP28C, ASP28D, CYS45C, CYS45D, GLU29D, GLU50C, GLU50D, GLU57C, GLU57D, GLY42C, GLY42D, GLY52C, GLY52D, ILE16D, ILE27C, ILE27D, ILE30C, ILE30D, ILE40C, ILE40D, LEU31C, LEU31D, LEU46C, LEU46D, LYS17C, LYS47C, LYS47D, LYS51C, LYS51D, MET53C, MET53D, MET59C, MET59D, PRO13D, PRO41C, PRO41D, PRO54C, PRO54D, SER26C, SER26D, SER43C, SER43D, THR55C, THR55D, TYR48C, TYR48D, VAL15C, VAL15D, VAL25D, VAL39D, VAL44C, VAL44D, VAL60C, VAL60D