2EK1

crystal structure of rna-binding motif of human rna-binding protein 12

• Total interactions analyzed: 28
• Total true interactions: 14
• Strongest Interaction:
  • Chains: A-D
  • Int. Res.: 32
  • Norm. En. per Res.: -2.9802
• Hub Node: A(5)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-40.1005	0.649	359.834	320.3824	55	13	7	5940	0	9	10
A-C	0.0	17.1776	-0.7073	16.4703	3	0	0	26	0	0	5
A-D	-19.8597	-14.9952	-60.5103	-95.3651	32	3	1	2583	2	5	6
A-G	0.0	-11.6826	-28.446	-40.1286	31	2	0	1460	0	11	5
A-H	0.0	0.0	-0.1596	-0.1596	2	0	0	23	0	0	0
B-C	-15.3859	-11.2591	-65.6535	-92.2985	32	6	0	2497	2	5	6
B-D	-10.2212	45.0359	-74.39	-39.5753	39	3	0	2785	0	3	10
B-G	0.0	-4.9534	-2.0416	-6.995	4	0	0	118	0	4	3
C-D	-41.2602	4.8091	329.89	293.4389	54	12	7	5930	0	9	9
C-G	0.0	0.0	-0.487	-0.487	11	0	0	63	0	6	1
C-H	0.0	0.0	-1.6335	-1.6335	8	0	0	158	0	1	0
E-F	-44.2349	9.4971	254.638	219.9001	57	19	7	6347	0	9	9
E-H	0.0	-5.528	-34.602	-40.13	34	0	0	2234	0	15	7
G-H	-40.6654	12.9858	426.183	398.5034	57	14	7	6109	0	9	10

Interface residues

• A-B: ALA920A, ALA920B, ALA923A, ALA923B, ASN911A, ASN911B, ASP890A, ASP890B, CYS907A, CYS907B, GLU891B, GLU912A, GLU912B, GLU919A, GLU919B, GLY904A, GLY904B, GLY914A, GLY914B, ILE889A, ILE889B, ILE892A, ILE892B, ILE902A, ILE902B, LEU893A, LEU893B, LEU908A, LEU908B, LYS879A, LYS909A, LYS909B, LYS913A, LYS913B, PRO875B, PRO903A, PRO903B, PRO916A, PRO916B, SER888A, SER888B, SER905A, SER905B, SER953A, THR917A, THR917B, TYR910A, TYR910B, VAL877A, VAL877B, VAL887A, VAL887B, VAL906A, VAL906B, VAL922B
• A-C: ASP890A, ASP890C, ILE889C
• A-D: ARG945D, ASN911A, ASN911D, ASP890A, GLU891A, GLU912A, GLU912D, GLY914A, GLY914D, GLY943A, GLY943D, ILE889A, ILE942A, ILE942D, LEU908A, LYS909A, LYS913A, LYS913D, PHE885A, PHE885D, PRO884A, PRO884D, PRO916A, PRO916D, SER888A, SER944D, THR886A, THR886D, THR917D, TYR910A, VAL887A, VAL887D
• A-G: ALA920G, ARG940A, ARG945G, ASN882G, ASN911G, GLN881G, GLN900A, GLU912G, GLU919G, GLU925A, GLU929A, GLY898A, GLY904A, GLY918G, ILE902A, LEU893A, LYS879G, LYS909G, LYS913G, LYS946G, LYS948G, PHE885G, PRO884G, PRO903A, PRO916G, SER926A, THR917G, TYR897A, TYR899A, TYR910G, VAL901A
• A-H: GLY904H, TYR897A
• B-C: ARG945B, ASN882B, ASN911B, ASN911C, ASP890C, GLU891C, GLU912B, GLU912C, GLY914B, GLY914C, GLY943B, ILE889C, ILE942B, ILE942C, LEU908C, LYS909C, LYS913B, LYS913C, PHE885B, PHE885C, PRO884B, PRO884C, PRO916B, PRO916C, SER888C, SER944B, THR886B, THR886C, THR917B, TYR910C, VAL887B, VAL887C
• B-D: ASP890B, ASP890D, ASP894D, CYS907B, CYS907D, GLU891B, GLU891D, GLY914B, GLY914D, GLY943B, GLY943D, ILE889B, ILE889D, ILE892B, ILE892D, ILE942B, ILE942D, LEU908B, LEU908D, LYS913B, LYS913D, PHE885B, PHE885D, PRO884B, PRO884D, PRO916B, PRO916D, SER888B, SER888D, SER944B, SER944D, THR886B, THR886D, TYR910B, TYR910D, VAL887B, VAL887D, VAL906B, VAL906D
• B-G: ASN938G, GLU912B, LYS913B, LYS948G
• C-D: ALA920C, ALA920D, ALA923C, ALA923D, ASN911C, ASN911D, ASP890C, ASP890D, CYS907C, CYS907D, GLU891D, GLU912C, GLU912D, GLU919C, GLU919D, GLY874D, GLY904C, GLY904D, GLY914C, GLY914D, ILE889C, ILE889D, ILE892C, ILE892D, ILE902C, ILE902D, LEU893C, LEU893D, LEU908C, LEU908D, LYS879C, LYS909C, LYS909D, LYS913C, LYS913D, PRO875D, PRO903C, PRO903D, PRO916C, PRO916D, SER888C, SER888D, SER905C, SER905D, SER953C, THR917C, TYR910C, TYR910D, VAL877C, VAL877D, VAL887D, VAL906C, VAL906D, VAL922D
• C-G: ARG927G, ARG940C, ASP894C, GLY943C, GLY951G, ILE935G, PHE895C, PRO941C, PRO952G, THR931G, TYR897C
• C-H: ARG927H, GLY898C, PRO875H, PRO952H, SER953H, THR876H, TYR897C, VAL877H
• E-F: ALA920E, ALA920F, ALA923E, ALA923F, ASN911E, ASN911F, ASP890E, ASP890F, CYS907E, CYS907F, GLU891F, GLU912E, GLU912F, GLU919E, GLU919F, GLY904E, GLY904F, GLY914E, GLY914F, ILE889E, ILE889F, ILE892E, ILE892F, ILE902E, ILE902F, LEU893E, LEU893F, LEU908E, LEU908F, LYS879E, LYS879F, LYS909E, LYS909F, LYS913E, LYS913F, PRO875E, PRO875F, PRO903E, PRO903F, PRO916E, PRO916F, SER888E, SER888F, SER905E, SER905F, SER953E, SER953F, THR917E, THR917F, TYR910E, TYR910F, VAL877E, VAL877F, VAL906E, VAL906F, VAL922E, VAL922F
• E-H: ALA930E, ALA932E, ALA933E, ARG927E, ARG945H, ASN882H, ASN938E, ASN938H, ASP928E, ASP936E, ASP939H, GLN881H, GLU919H, GLY918H, GLY951E, GLY951H, ILE878E, ILE935E, ILE935H, LEU949E, LEU949H, LYS879H, LYS946H, LYS948H, PRO952E, SER950E, SER950H, SER953E, THR917H, THR931E, VAL880H, VAL934E, VAL934H, VAL947H
• G-H: ALA920G, ALA920H, ALA923G, ALA923H, ASN911G, ASN911H, ASP890G, ASP890H, ASP894G, CYS907G, CYS907H, GLU891G, GLU912G, GLU912H, GLU919G, GLU919H, GLY904G, GLY904H, GLY914G, GLY914H, ILE889G, ILE889H, ILE892G, ILE892H, ILE902G, ILE902H, LEU893G, LEU893H, LEU908G, LEU908H, LYS879G, LYS879H, LYS909G, LYS909H, LYS913G, LYS913H, PRO903G, PRO903H, PRO916G, PRO916H, SER888G, SER888H, SER905G, SER905H, SER953H, THR876G, THR917G, THR917H, TYR910G, TYR910H, VAL877G, VAL877H, VAL887G, VAL901G, VAL906G, VAL906H, VAL922G