2EJW

homoserine dehydrogenase from thermus thermophilus hb8

• Total interactions analyzed: 6
• Total true interactions: 3
• Strongest Interaction:
  • Chains: E-F
  • Int. Res.: 198
  • Norm. En. per Res.: -4.052
• Hub Node: A(1)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-79.8113	-146.6039	-532.176	-758.5912	196	23	8	21305	12	42	42
B-E	-23.0101	15.9536	-262.58	-269.6365	123	10	11	12845	2	49	62
E-F	-89.2927	-183.7207	-529.281	-802.2944	198	20	6	21407	11	44	43

Interface residues

• A-B: ALA122A, ALA122B, ALA126A, ALA126B, ALA130A, ALA130B, ALA17A, ALA17B, ALA265A, ALA265B, ALA267A, ALA267B, ALA26A, ALA26B, ALA271A, ALA271B, ALA276A, ALA276B, ALA282A, ALA282B, ALA289A, ALA289B, ALA293A, ALA293B, ALA295A, ALA295B, ALA300A, ALA300B, ALA309A, ALA309B, ALA315A, ALA315B, ALA318A, ALA31A, ALA31B, ARG138A, ARG138B, ARG235B, ARG25A, ARG25B, ARG266A, ARG266B, ARG268A, ARG268B, ARG275A, ARG277A, ARG277B, ARG304A, ARG304B, ARG317A, ARG317B, ARG319A, ARG319B, ASN270A, ASN270B, ASP261A, ASP261B, ASP301A, ASP301B, GLN260A, GLN260B, GLU121A, GLU121B, GLU135A, GLU135B, GLU141A, GLU141B, GLU24A, GLU24B, GLU27A, GLU27B, GLU281A, GLU281B, GLU28A, GLU28B, GLY116A, GLY116B, GLY127A, GLY127B, GLY139A, GLY139B, GLY269A, GLY269B, GLY280A, GLY280B, GLY286A, GLY286B, GLY288A, GLY288B, GLY290A, GLY290B, GLY291A, GLY291B, GLY292A, GLY292B, GLY297A, GLY297B, GLY308A, GLY308B, GLY311A, GLY311B, GLY33A, GLY33B, HIS262A, HIS262B, HIS312A, HIS312B, LEU131A, LEU131B, LEU134A, LEU134B, LEU137A, LEU137B, LEU142A, LEU142B, LEU203A, LEU203B, LEU21A, LEU21B, LEU258A, LEU264A, LEU272A, LEU272B, LEU279A, LEU279B, LEU298A, LEU298B, LEU29A, LEU29B, LEU302A, LEU302B, LEU303A, LEU303B, LEU306A, LEU306B, LEU313A, LEU313B, LEU322A, LEU322B, MET125A, MET125B, MET1A, PHE133A, PHE133B, PHE18A, PHE18B, PHE283A, PHE283B, PHE299A, PHE299B, PHE32A, PHE32B, PRO129A, PRO129B, PRO259A, PRO263A, PRO263B, PRO278A, PRO278B, PRO287A, PRO287B, PRO310A, PRO310B, PRO314A, PRO314B, PRO316A, PRO316B, SER132A, SER132B, SER140A, SER140B, SER296A, SER296B, SER307A, SER307B, SER30A, SER30B, THR128A, THR128B, THR136A, THR136B, THR285A, THR285B, THR294A, THR294B, TRP273A, TRP273B, TRP328A, VAL124A, VAL204A, VAL204B, VAL274A, VAL274B, VAL284A, VAL284B, VAL34A
• B-E: ALA100B, ALA100E, ALA167B, ALA167E, ALA169B, ALA169E, ALA179B, ALA179E, ALA181B, ALA181E, ALA219B, ALA219E, ALA59B, ALA59E, ALA79B, ALA79E, ARG164B, ARG164E, ARG175B, ARG175E, ARG220B, ARG220E, ARG44B, ARG44E, ARG47B, ARG47E, ARG58B, ARG58E, ARG82B, ARG82E, ASP182B, ASP182E, ASP45B, ASP45E, GLN174B, GLN174E, GLU104B, GLU104E, GLU168B, GLU168E, GLU172B, GLU172E, GLU180B, GLU180E, GLU188B, GLU188E, GLU224B, GLU224E, GLU60B, GLU60E, GLU78B, GLU78E, GLY10B, GLY10E, GLY12B, GLY75B, GLY75E, GLY76B, GLY76E, HIS194B, HIS194E, ILE156B, ILE156E, ILE190B, ILE190E, ILE218B, ILE218E, LEU157B, LEU170B, LEU170E, LEU171B, LEU171E, LEU176E, LEU185B, LEU185E, LEU221B, LEU221E, LEU226E, LEU42B, LEU42E, LEU81B, LEU81E, LEU83B, LEU83E, LEU9B, LEU9E, LYS48B, LYS48E, MET160B, MET160E, MET74B, MET74E, PHE62B, PHE62E, PRO183B, PRO183E, PRO223B, PRO223E, PRO46B, PRO46E, PRO49B, PRO49E, PRO61B, PRO61E, PRO80B, PRO80E, THR165B, THR165E, THR184B, THR184E, THR222B, THR222E, TYR166B, TYR166E, VAL187B, VAL187E, VAL225B, VAL225E, VAL43B, VAL43E, VAL77B, VAL77E, VAL84E
• E-F: ALA122E, ALA122F, ALA126E, ALA126F, ALA130E, ALA130F, ALA17E, ALA17F, ALA265E, ALA265F, ALA267E, ALA267F, ALA26E, ALA26F, ALA271E, ALA271F, ALA276E, ALA276F, ALA282E, ALA282F, ALA289E, ALA289F, ALA293E, ALA293F, ALA295E, ALA295F, ALA300E, ALA300F, ALA309E, ALA309F, ALA315E, ALA315F, ALA318E, ALA318F, ALA31E, ALA31F, ARG138E, ARG138F, ARG235F, ARG25E, ARG25F, ARG266E, ARG266F, ARG268E, ARG268F, ARG275E, ARG275F, ARG277E, ARG277F, ARG304E, ARG304F, ARG317E, ARG317F, ARG319E, ARG319F, ASN270E, ASN270F, ASP261E, ASP261F, ASP301E, ASP301F, GLN260E, GLN260F, GLU121E, GLU121F, GLU135E, GLU135F, GLU141E, GLU141F, GLU24E, GLU24F, GLU27E, GLU27F, GLU281E, GLU281F, GLU28E, GLU28F, GLY116E, GLY116F, GLY127E, GLY127F, GLY139E, GLY139F, GLY269E, GLY269F, GLY280E, GLY280F, GLY286E, GLY286F, GLY288E, GLY288F, GLY290E, GLY290F, GLY291E, GLY291F, GLY292E, GLY292F, GLY297E, GLY297F, GLY308E, GLY308F, GLY311E, GLY311F, GLY33E, GLY33F, HIS262E, HIS262F, HIS312E, HIS312F, LEU131E, LEU131F, LEU134E, LEU134F, LEU137E, LEU137F, LEU142E, LEU142F, LEU203E, LEU203F, LEU21E, LEU21F, LEU264E, LEU264F, LEU272E, LEU272F, LEU279E, LEU279F, LEU298E, LEU298F, LEU29E, LEU29F, LEU302E, LEU302F, LEU303E, LEU303F, LEU306E, LEU306F, LEU313E, LEU313F, LEU322E, LEU322F, MET125E, MET125F, PHE133E, PHE133F, PHE18E, PHE18F, PHE283E, PHE283F, PHE299E, PHE299F, PHE32E, PHE32F, PRO129E, PRO129F, PRO259F, PRO263E, PRO263F, PRO278E, PRO278F, PRO287E, PRO287F, PRO310E, PRO310F, PRO314E, PRO314F, PRO316E, PRO316F, PRO320E, PRO320F, SER132E, SER132F, SER140E, SER140F, SER296E, SER296F, SER307E, SER307F, SER30E, SER30F, THR128E, THR128F, THR136E, THR136F, THR285E, THR285F, THR294E, THR294F, TRP273E, TRP273F, TRP328F, VAL124F, VAL204E, VAL204F, VAL274E, VAL274F, VAL284E, VAL284F