2EB1

crystal structure of the c-terminal rnase iii domain of human dicer

• Total interactions analyzed: 3
• Total true interactions: 2
• Strongest Interaction:
  • Chains: A-C
  • Int. Res.: 107
  • Norm. En. per Res.: -3.8466
• Hub Node: A(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-25.7442	8.1908	-155.153	-172.7064	67	6	5	6423	0	17	17
A-C	-27.0477	-2.2763	-382.261	-411.585	107	11	11	13443	2	31	24

Interface residues

• A-B: ALA102A, ALA23B, ALA32B, ARG45B, ASN10A, ASN21B, ASN2A, ASN2B, ASN37B, ASP112A, ASP113A, ASP41B, ASP95A, CYS42B, GLN116A, GLN27B, GLN44B, GLU106A, GLY7A, HIS109A, HIS31A, HIS35A, HIS35B, HIS3A, HIS3B, HIS97A, ILE111A, ILE39B, ILE5B, LEU107A, LEU119A, LEU25B, LEU26B, LEU46B, LEU4A, LEU4B, LYS101A, LYS20B, LYS22B, LYS98A, MET150A, MET163B, PHE100A, PHE108A, PHE19B, PHE29A, PHE8A, PHE8B, PRO105A, SER104A, SER33A, SER33B, SER6A, SER6B, THR30A, THR38B, THR40B, TYR24B, TYR34A, TYR34B, TYR36A, TYR36B, TYR99A, VAL103A, VAL103B, VAL110A, VAL115A
• A-C: ALA160A, ALA160C, ALA32A, ALA32C, ALA52A, ALA52C, ARG45A, ARG45C, ARG67A, ARG67C, ARG78A, ARG78C, ASP41A, ASP41C, ASP51A, ASP51C, ASP55A, ASP55C, ASP65A, ASP65C, ASP76A, ASP76C, CYS42A, CYS42C, GLN27A, GLN27C, GLN44A, GLN44C, GLN68A, GLN68C, GLU155A, GLU155C, GLU47A, GLU47C, GLU64A, GLU64C, GLY159A, GLY159C, GLY166C, GLY50A, GLY50C, GLY72A, GLY72C, HIS61A, HIS61C, HIS69A, HIS69C, ILE53A, ILE53C, ILE58A, ILE58C, LEU169A, LEU169C, LEU46A, LEU46C, LEU49A, LEU49C, LEU54A, LEU54C, LEU57A, LEU57C, LEU62A, LEU62C, LEU74A, LEU74C, LEU77A, LEU77C, LEU81A, LEU81C, LYS60A, LYS60C, MET163A, MET163C, MET167A, MET167C, PHE48A, PHE48C, PRO66A, PRO66C, PRO71A, PRO71C, SER168A, SER168C, SER70A, SER70C, SER79A, SER79C, THR59A, THR59C, THR75A, THR75C, TYR162A, TYR162C, TYR24A, TYR24C, TYR43A, TYR43C, TYR56A, TYR56C, TYR63A, TYR63C, VAL172A, VAL172C, VAL73A, VAL73C, VAL82A, VAL82C