2EAK

crystal structure of human galectin-9 n-terminal crd in complex with lactose

• Total interactions analyzed: 3
• Total true interactions: 3
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 46
  • Norm. En. per Res.: -2.4217
• Hub Node: A(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-18.2286	0.0	-93.1684	-111.397	46	2	0	3623	0	3	1
A-C	-7.6089	0.0	-21.6895	-29.2984	24	0	0	1229	0	4	2
B-C	-8.3408	-1.3948	-29.0252	-38.7608	45	2	0	1588	1	8	8

Interface residues

• A-B: ALA8A, ARG125B, ARG130A, ARG77B, ASN56B, ASN75B, ASN79B, ASP132A, ASP57A, GLN22A, GLN50A, GLN78B, GLN7A, GLU85B, GLU86B, GLY19A, GLY23A, GLY24A, GLY52A, GLY80B, GLY83B, HIS124B, ILE134A, ILE145A, ILE21A, LEU11A, PHE123B, PHE147A, PHE17A, PHE53A, PRO127B, PRO84B, PRO9A, SER135A, SER18A, SER54A, SER6A, SER81B, THR133A, THR20A, THR51A, THR76B, TRP82B, TYR10A, VAL126B, VAL131A
• A-C: ARG125C, ARG130A, ASN56A, ASN56C, ASN79A, ASN79C, ASP132A, ASP57A, ASP57C, GLN78C, GLY52A, GLY55A, GLY80A, GLY80C, GLY83C, PHE53A, PRO127C, PRO84C, SER54A, SER54C, SER81C, THR51A, TRP82C, VAL126C
• B-C: ARG130B, ARG44C, ARG77C, ASN137C, ASN56B, ASN56C, ASN79B, ASN79C, ASP132B, ASP57B, GLN22B, GLN26B, GLN50C, GLN78B, GLN78C, GLY138C, GLY19B, GLY23B, GLY24B, GLY42C, GLY52B, GLY55B, GLY55C, GLY80B, GLY80C, HIS129B, ILE21B, LEU38C, PHE53B, PHE53C, PRO16C, SER139C, SER18B, SER18C, SER40C, SER41C, SER54B, SER54C, SER81C, THR133B, THR20B, THR43C, THR51B, TRP82C, VAL15C