2E7S

crystal structure of the yeast sec2p gef domain

• Total interactions analyzed: 190
• Total true interactions: 33
• Strongest Interaction:
  • Chains: D-R
  • Int. Res.: 43
  • Norm. En. per Res.: -4.1484
• Hub Node: C(5)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-40.4054	-109.6155	-426.252	-576.2729	190	53	29	20835	13	94	105
A-E	0.0	0.0	-0.009	-0.009	2	0	0	6	0	0	0
C-D	-49.9088	-151.7101	-332.789	-534.4079	180	60	29	19844	12	104	109
C-E	0.0	0.0	-0.0145	-0.0145	2	0	0	8	0	1	0
C-F	0.0	0.0	-0.4072	-0.4072	4	0	0	40	0	0	0
C-Q	-19.8294	8.6106	-129.602	-140.8208	60	20	10	6568	3	21	20
C-R	0.0	0.0	-0.0857	-0.0857	6	0	0	24	0	0	2
D-G	0.0	0.0	-1.9652	-1.9652	4	0	0	87	0	0	1
D-Q	-14.1158	-1.2214	-83.1046	-98.4418	62	9	3	4082	0	14	14
D-R	-22.643	-92.5574	-63.1815	-178.3819	43	9	0	2643	6	15	12
E-F	-24.3396	-87.5434	-453.463	-565.346	200	66	31	23335	7	99	104
G-H	-22.3519	-107.1204	-388.74	-518.2124	177	77	27	19611	15	85	98
G-I	0.0	0.0	-0.0004	-0.0004	2	0	0	1	0	0	0
G-Q	-27.1218	-73.8316	-56.3466	-157.3	45	10	1	2773	5	16	14
G-R	0.0	-3.8901	-92.4579	-96.348	59	13	4	4216	0	12	13
H-I	0.0	0.0	-1.0472	-1.0472	3	0	0	62	0	0	0
H-Q	0.0	0.0	-0.072	-0.072	6	0	0	30	0	1	2
H-R	-17.1014	-0.7167	-166.645	-184.4631	67	33	11	7667	2	25	25
I-J	-47.0156	-150.2702	-276.736	-474.0217	166	72	26	17109	12	82	93
J-M	0.0	0.0	-0.0048	-0.0048	2	0	0	5	0	1	1
J-N	0.0	0.0	-0.2718	-0.2718	7	0	0	60	0	0	1
K-L	-35.5471	-125.9725	-442.223	-603.7426	187	71	34	21291	11	92	107
K-O	0.0	0.0	-0.0619	-0.0619	3	0	0	16	0	0	0
M-N	-49.6641	-150.1831	-364.785	-564.6322	175	59	30	19388	11	103	109
M-O	0.0	0.0	-0.0088	-0.0088	2	0	0	3	0	0	0
M-P	0.0	0.0	-1.1954	-1.1954	4	0	0	67	0	0	0
N-Q	0.0	0.0	-2.1271	-2.1271	4	0	0	98	0	0	1
O-P	-43.5618	-140.6963	-433.503	-617.7611	182	69	34	20733	13	97	102
Q-R	-37.6574	-145.4103	-331.701	-514.7687	175	68	27	19601	11	88	102
Q-S	0.0	0.0	-0.0003	-0.0003	2	0	0	1	0	0	0
R-S	0.0	0.0	-1.1413	-1.1413	4	0	0	56	0	0	0
R-T	0.0	0.0	-0.0032	-0.0032	2	0	0	1	0	0	0
S-T	-19.2363	-129.055	-312.121	-460.4123	171	49	24	18158	12	88	105

Interface residues

• A-B: ALA106A, ALA106B, ALA112A, ALA112B, ALA117A, ALA117B, ALA119A, ALA119B, ALA125A, ALA125B, ALA47B, ALA48A, ALA48B, ALA81B, ALA90A, ALA90B, ALA94A, ALA94B, ARG120A, ARG120B, ARG132A, ARG132B, ARG138A, ARG138B, ARG64A, ARG64B, ARG69A, ARG69B, ARG75A, ARG75B, ARG77A, ARG77B, ARG87A, ARG87B, ASN113A, ASN113B, ASN114A, ASN114B, ASN130A, ASN130B, ASN51A, ASN51B, ASN53A, ASN53B, ASN60A, ASN60B, ASN84A, ASN84B, ASN98A, ASN98B, ASP110A, ASP110B, ASP118A, ASP118B, ASP141A, ASP141B, ASP145B, ASP58A, ASP58B, ASP68A, ASP68B, ASP70A, ASP70B, ASP71A, ASP71B, ASP79A, ASP79B, GLN136A, GLN136B, GLN34B, GLN45A, GLN45B, GLN54A, GLN54B, GLU102A, GLU102B, GLU111A, GLU111B, GLU122A, GLU122B, GLU127A, GLU127B, GLU135A, GLU135B, GLU139A, GLU139B, GLU50A, GLU50B, GLU57A, GLU57B, GLU65A, GLU65B, GLU72A, GLU72B, GLU78A, GLU78B, GLU83A, GLU83B, GLU85A, GLU85B, GLU91B, GLU92B, ILE126A, ILE126B, ILE128A, ILE128B, ILE49A, ILE49B, ILE80A, ILE80B, LEU104A, LEU104B, LEU108A, LEU108B, LEU115A, LEU115B, LEU129A, LEU129B, LEU133A, LEU133B, LEU137A, LEU137B, LEU143A, LEU143B, LEU144A, LEU144B, LEU147B, LEU151B, LEU55A, LEU55B, LEU62A, LEU62B, LEU66A, LEU66B, LEU76A, LEU76B, LEU86A, LEU86B, LEU97A, LEU97B, LYS123A, LYS123B, LYS131A, LYS131B, LYS140A, LYS140B, LYS37A, LYS37B, LYS56A, LYS56B, LYS63A, LYS63B, LYS74A, LYS74B, LYS82A, LYS89B, LYS99B, PHE109A, PHE109B, SER107A, SER107B, SER38A, SER44A, SER44B, SER67A, SER67B, THR105A, THR105B, THR134A, THR134B, THR146B, THR148B, THR41A, THR41B, THR61A, THR61B, THR88A, THR88B, TYR124A, TYR124B, TYR52A, TYR52B, TYR59A, TYR59B, VAL101A, VAL101B, VAL116A, VAL116B, VAL73A, VAL73B
• A-E: PHE109A, PHE109E
• C-D: ALA106C, ALA106D, ALA112C, ALA112D, ALA117C, ALA117D, ALA119C, ALA119D, ALA125C, ALA125D, ALA48C, ALA48D, ALA81D, ALA90C, ALA90D, ALA94C, ALA94D, ARG120C, ARG120D, ARG132C, ARG132D, ARG138C, ARG138D, ARG64C, ARG64D, ARG69C, ARG69D, ARG75C, ARG75D, ARG77C, ARG77D, ARG87C, ARG87D, ASN113C, ASN113D, ASN114D, ASN130C, ASN130D, ASN51C, ASN51D, ASN53C, ASN53D, ASN60C, ASN60D, ASN84C, ASN84D, ASN98C, ASN98D, ASP110C, ASP110D, ASP118C, ASP118D, ASP141C, ASP141D, ASP145C, ASP58C, ASP58D, ASP68C, ASP68D, ASP70C, ASP70D, ASP71C, ASP71D, ASP79C, ASP79D, GLN136C, GLN136D, GLN150D, GLN45C, GLN45D, GLN54C, GLN54D, GLU102C, GLU102D, GLU111C, GLU111D, GLU122C, GLU122D, GLU127C, GLU127D, GLU135C, GLU135D, GLU139C, GLU139D, GLU50C, GLU50D, GLU57C, GLU57D, GLU65C, GLU65D, GLU72C, GLU72D, GLU78D, GLU83C, GLU83D, GLU85C, GLU91C, GLU91D, GLU92C, ILE126C, ILE126D, ILE128C, ILE49C, ILE49D, ILE80C, ILE80D, LEU104C, LEU104D, LEU108C, LEU108D, LEU115C, LEU115D, LEU129C, LEU129D, LEU133C, LEU133D, LEU137C, LEU137D, LEU143C, LEU143D, LEU144C, LEU144D, LEU147C, LEU147D, LEU149D, LEU151D, LEU55C, LEU55D, LEU62C, LEU62D, LEU66C, LEU66D, LEU76C, LEU76D, LEU86C, LEU97C, LEU97D, LYS123C, LYS123D, LYS131C, LYS131D, LYS140C, LYS140D, LYS56C, LYS56D, LYS63C, LYS63D, LYS74C, LYS74D, LYS89C, PHE109C, PHE109D, SER44C, SER44D, SER67C, SER67D, THR105C, THR105D, THR134C, THR134D, THR148C, THR148D, THR41C, THR41D, THR61C, THR61D, THR88C, THR88D, TYR124C, TYR124D, TYR52C, TYR52D, TYR59C, TYR59D, VAL101C, VAL101D, VAL116C, VAL116D, VAL73C, VAL73D
• C-E: ARG120C, GLU111E
• C-F: ASN113C, ASN113F, PHE109C, PHE109F
• C-Q: ALA106C, ALA112C, ALA117C, ALA119C, ALA125C, ALA43Q, ALA47Q, ALA48Q, ALA90C, ALA94C, ASN113C, ASN114C, ASN36Q, ASN51Q, ASN53Q, ASN60Q, ASN98C, ASP103C, ASP110C, ASP118C, ASP95C, GLN45Q, GLN54Q, GLU100C, GLU102C, GLU111C, GLU122C, GLU32Q, GLU33Q, GLU50Q, GLU57Q, GLU93C, ILE126C, ILE42Q, ILE49Q, LEU104C, LEU108C, LEU115C, LEU35Q, LEU39Q, LEU97C, LYS123C, LYS37Q, LYS40Q, LYS46Q, LYS56Q, LYS63Q, LYS96C, LYS99C, PHE109C, SER107C, SER38Q, SER44Q, THR105C, THR41Q, TYR124C, TYR52Q, TYR59Q, VAL101C, VAL116C
• C-R: ASN51R, ASP118C, GLU122C, LEU115C, LEU55R, LEU62R
• D-G: ASN113D, ASN113G, PHE109D, PHE109G
• D-Q: ALA106D, ALA112D, ALA117D, ALA119D, ALA43Q, ALA47Q, ALA48Q, ALA90D, ALA94D, ARG120D, ARG138D, ARG77Q, ARG87D, ASN113D, ASN36Q, ASN51Q, ASN53Q, ASN60Q, ASN98D, ASP103D, ASP110D, ASP95D, GLN34Q, GLN45Q, GLU100D, GLU102D, GLU111D, GLU127D, GLU32Q, GLU50Q, GLU91D, GLU92D, GLU93D, ILE126D, ILE42Q, ILE49Q, LEU104D, LEU108D, LEU115D, LEU31Q, LEU35Q, LEU39Q, LEU97D, LYS123D, LYS37Q, LYS46Q, LYS56Q, LYS63Q, LYS74Q, LYS96D, LYS99D, PHE109D, SER107D, SER38Q, SER44Q, THR105D, THR41Q, THR88D, TYR52Q, TYR59Q, VAL101D, VAL116D
• D-R: ALA106D, ALA112D, ALA117D, ALA119D, ALA43R, ALA47R, ALA48R, ARG120D, ARG138D, ARG69R, ASN113D, ASN114D, ASN51R, ASP103D, ASP110D, ASP118D, ASP58R, GLN45R, GLN54R, GLU102D, GLU111D, GLU127D, GLU50R, GLU57R, ILE42R, ILE49R, LEU115D, LEU55R, LEU62R, LYS123D, LYS37R, LYS40R, LYS46R, LYS99D, PHE109D, SER107D, SER44R, THR41R, THR61R, TYR124D, TYR52R, TYR59R, VAL116D
• E-F: ALA106F, ALA112E, ALA112F, ALA117E, ALA117F, ALA119E, ALA119F, ALA125E, ALA125F, ALA47E, ALA47F, ALA48E, ALA48F, ALA81E, ALA81F, ALA90E, ALA90F, ALA94E, ALA94F, ARG120E, ARG120F, ARG132E, ARG132F, ARG138E, ARG138F, ARG64E, ARG64F, ARG69E, ARG69F, ARG75E, ARG75F, ARG77E, ARG77F, ARG87E, ARG87F, ASN113E, ASN113F, ASN114F, ASN130E, ASN130F, ASN153E, ASN153F, ASN51E, ASN51F, ASN53E, ASN53F, ASN60E, ASN60F, ASN84E, ASN84F, ASN98E, ASN98F, ASP110E, ASP110F, ASP118E, ASP118F, ASP141E, ASP141F, ASP145E, ASP145F, ASP58E, ASP58F, ASP68E, ASP68F, ASP70E, ASP70F, ASP71E, ASP71F, ASP79E, ASP79F, GLN136E, GLN136F, GLN150E, GLN150F, GLN45E, GLN45F, GLN54E, GLN54F, GLU102E, GLU111E, GLU111F, GLU122E, GLU122F, GLU127E, GLU127F, GLU135E, GLU139E, GLU139F, GLU50E, GLU50F, GLU57E, GLU57F, GLU65E, GLU65F, GLU72E, GLU72F, GLU78E, GLU78F, GLU83E, GLU83F, GLU85F, GLU91E, GLU91F, ILE126E, ILE126F, ILE128E, ILE128F, ILE42E, ILE49E, ILE49F, ILE80E, ILE80F, LEU104E, LEU104F, LEU108E, LEU108F, LEU115E, LEU115F, LEU129E, LEU129F, LEU133E, LEU133F, LEU137E, LEU137F, LEU143E, LEU143F, LEU144E, LEU144F, LEU147E, LEU147F, LEU149E, LEU149F, LEU151E, LEU151F, LEU154E, LEU154F, LEU55E, LEU55F, LEU62E, LEU62F, LEU66E, LEU66F, LEU76E, LEU76F, LEU86E, LEU86F, LEU97E, LEU97F, LYS123E, LYS123F, LYS131E, LYS131F, LYS140E, LYS140F, LYS152E, LYS37E, LYS37F, LYS56E, LYS56F, LYS63E, LYS63F, LYS74E, LYS74F, LYS82F, PHE109E, PHE109F, SER107E, SER107F, SER38E, SER38F, SER44E, SER44F, SER67E, SER67F, THR105E, THR105F, THR134E, THR134F, THR146E, THR146F, THR148E, THR148F, THR41E, THR41F, THR61E, THR61F, THR88E, THR88F, TYR124E, TYR124F, TYR52E, TYR52F, TYR59E, TYR59F, VAL101E, VAL101F, VAL116E, VAL116F, VAL73E, VAL73F
• G-H: ALA106G, ALA106H, ALA112G, ALA112H, ALA117G, ALA117H, ALA119G, ALA119H, ALA125G, ALA125H, ALA47H, ALA48G, ALA48H, ALA81G, ALA81H, ALA90G, ALA90H, ALA94G, ALA94H, ARG120G, ARG120H, ARG132G, ARG132H, ARG64G, ARG64H, ARG69G, ARG69H, ARG75G, ARG75H, ARG77G, ARG77H, ARG87G, ARG87H, ASN113G, ASN113H, ASN114G, ASN114H, ASN130G, ASN130H, ASN51G, ASN51H, ASN53G, ASN53H, ASN60G, ASN60H, ASN84G, ASN84H, ASN98G, ASN98H, ASP110G, ASP110H, ASP118G, ASP118H, ASP58G, ASP58H, ASP68G, ASP68H, ASP70G, ASP70H, ASP71H, ASP79G, ASP79H, GLN136G, GLN136H, GLN34G, GLN34H, GLN45G, GLN45H, GLN54G, GLN54H, GLU100G, GLU102G, GLU102H, GLU111G, GLU111H, GLU122G, GLU122H, GLU127G, GLU127H, GLU135G, GLU135H, GLU50G, GLU50H, GLU57G, GLU57H, GLU65G, GLU65H, GLU72G, GLU72H, GLU78G, GLU78H, GLU83G, GLU83H, GLU85H, GLU91G, GLU91H, GLU92G, ILE126G, ILE126H, ILE128G, ILE128H, ILE49G, ILE49H, ILE80G, ILE80H, LEU104G, LEU104H, LEU108G, LEU108H, LEU115G, LEU115H, LEU129G, LEU129H, LEU133G, LEU133H, LEU137G, LEU137H, LEU55G, LEU55H, LEU62G, LEU62H, LEU66G, LEU66H, LEU76G, LEU76H, LEU86G, LEU86H, LEU97G, LYS123G, LYS123H, LYS131G, LYS131H, LYS140G, LYS37G, LYS37H, LYS56G, LYS56H, LYS63G, LYS63H, LYS74G, LYS74H, LYS82G, LYS82H, LYS89G, LYS89H, PHE109G, PHE109H, SER107G, SER107H, SER38G, SER38H, SER44G, SER44H, SER67G, SER67H, THR105G, THR105H, THR134G, THR134H, THR41G, THR41H, THR61G, THR61H, THR88G, THR88H, TYR124G, TYR124H, TYR52G, TYR52H, TYR59G, TYR59H, VAL101G, VAL101H, VAL116G, VAL116H, VAL73G, VAL73H
• G-I: ARG120I, LEU104G
• G-Q: ALA106G, ALA112G, ALA117G, ALA119G, ALA43Q, ALA47Q, ALA48Q, ARG120G, ASN113G, ASN114G, ASN51Q, ASN53Q, ASN98G, ASP103G, ASP110G, ASP118G, ASP58Q, GLN45Q, GLN54Q, GLU102G, GLU111G, GLU127G, GLU33Q, GLU50Q, GLU57Q, ILE42Q, ILE49Q, LEU115G, LEU55Q, LYS123G, LYS131G, LYS37Q, LYS40Q, LYS46Q, LYS56Q, LYS99G, PHE109G, SER107G, SER44Q, THR41Q, THR61Q, TYR124G, TYR52Q, TYR59Q, VAL116G
• G-R: ALA106G, ALA112G, ALA117G, ALA119G, ALA43R, ALA47R, ALA48R, ALA90G, ALA94G, ARG120G, ARG87G, ASN113G, ASN36R, ASN51R, ASN53R, ASN60R, ASN98G, ASP103G, ASP110G, ASP95G, GLN34R, GLN45R, GLU100G, GLU102G, GLU127G, GLU32R, GLU33R, GLU50R, GLU91G, GLU92G, GLU93G, ILE42R, ILE49R, LEU104G, LEU108G, LEU115G, LEU31R, LEU35R, LEU39R, LEU97G, LYS123G, LYS37R, LYS46R, LYS56R, LYS63R, LYS96G, LYS99G, PHE109G, SER107G, SER38R, SER44R, THR105G, THR41R, THR88G, TYR124G, TYR52R, TYR59R, VAL101G, VAL116G
• H-I: ASN113H, PHE109H, PHE109I
• H-Q: ASN51Q, GLN54Q, GLU122H, LEU115H, LEU55Q, LEU62Q
• H-R: ALA106H, ALA112H, ALA117H, ALA119H, ALA125H, ALA43R, ALA47R, ALA48R, ALA90H, ALA94H, ARG132H, ARG87H, ASN113H, ASN114H, ASN36R, ASN51R, ASN53R, ASN60R, ASN98H, ASP103H, ASP110H, ASP118H, ASP95H, GLN136H, GLN45R, GLN54R, GLU100H, GLU102H, GLU111H, GLU122H, GLU32R, GLU33R, GLU50R, GLU57R, GLU93H, ILE126H, ILE42R, ILE49R, LEU104H, LEU108H, LEU115H, LEU129H, LEU31R, LEU35R, LEU39R, LEU97H, LYS123H, LYS37R, LYS40R, LYS46R, LYS56R, LYS63R, LYS74R, LYS89H, LYS96H, LYS99H, PHE109H, SER107H, SER38R, SER44R, SER67R, THR105H, THR41R, TYR52R, TYR59R, VAL101H, VAL116H
• I-J: ALA106J, ALA112I, ALA112J, ALA117I, ALA117J, ALA119I, ALA119J, ALA125I, ALA125J, ALA47I, ALA47J, ALA48I, ALA48J, ALA81I, ALA81J, ALA90I, ALA94I, ALA94J, ARG120I, ARG120J, ARG132I, ARG132J, ARG138I, ARG64I, ARG64J, ARG69I, ARG69J, ARG75I, ARG75J, ARG77I, ARG77J, ARG87I, ARG87J, ASN113I, ASN113J, ASN130I, ASN130J, ASN51I, ASN51J, ASN53I, ASN53J, ASN60I, ASN60J, ASN84I, ASN84J, ASN98I, ASN98J, ASP110I, ASP118I, ASP118J, ASP141I, ASP58I, ASP58J, ASP68I, ASP68J, ASP70I, ASP70J, ASP71I, ASP71J, ASP79I, ASP79J, GLN136I, GLN136J, GLN34I, GLN34J, GLN45I, GLN45J, GLN54I, GLN54J, GLU102I, GLU102J, GLU111I, GLU111J, GLU122I, GLU122J, GLU127I, GLU127J, GLU135I, GLU135J, GLU139I, GLU50I, GLU50J, GLU57I, GLU57J, GLU65I, GLU65J, GLU72I, GLU72J, GLU78I, GLU78J, GLU83I, GLU83J, GLU91I, GLU91J, ILE126I, ILE126J, ILE128I, ILE128J, ILE42J, ILE49I, ILE49J, ILE80I, ILE80J, LEU104I, LEU104J, LEU108I, LEU108J, LEU115I, LEU115J, LEU129I, LEU129J, LEU133I, LEU133J, LEU137I, LEU137J, LEU144I, LEU55I, LEU55J, LEU62I, LEU62J, LEU66I, LEU66J, LEU76I, LEU76J, LEU86I, LEU97J, LYS123I, LYS123J, LYS131I, LYS131J, LYS140I, LYS37I, LYS56I, LYS56J, LYS63I, LYS63J, LYS74I, LYS74J, LYS82J, PHE109I, PHE109J, SER38I, SER38J, SER44I, SER44J, SER67I, SER67J, THR105I, THR105J, THR134I, THR134J, THR41I, THR41J, THR61I, THR61J, THR88I, TYR52I, TYR52J, TYR59I, TYR59J, VAL101I, VAL101J, VAL116I, VAL116J, VAL73I, VAL73J
• J-M: LYS40M, LYS46J
• J-N: GLU32J, ILE42J, ILE42N, LEU31N, LEU35J, LEU35N, SER38N
• K-L: ALA106K, ALA106L, ALA112K, ALA112L, ALA117K, ALA117L, ALA119K, ALA119L, ALA125K, ALA125L, ALA48K, ALA48L, ALA81K, ALA81L, ALA90L, ALA94K, ALA94L, ARG120K, ARG120L, ARG132K, ARG132L, ARG138K, ARG138L, ARG64K, ARG64L, ARG69K, ARG69L, ARG75K, ARG75L, ARG77K, ARG77L, ARG87K, ARG87L, ASN113K, ASN113L, ASN114K, ASN114L, ASN130K, ASN130L, ASN51K, ASN51L, ASN53K, ASN53L, ASN60K, ASN60L, ASN84K, ASN84L, ASN98K, ASN98L, ASP110K, ASP110L, ASP118K, ASP118L, ASP141K, ASP141L, ASP145K, ASP58K, ASP58L, ASP68K, ASP68L, ASP70K, ASP70L, ASP71K, ASP71L, ASP79K, ASP79L, GLN136K, GLN136L, GLN34K, GLN34L, GLN45K, GLN45L, GLN54K, GLN54L, GLU102K, GLU102L, GLU111K, GLU111L, GLU122K, GLU122L, GLU127K, GLU127L, GLU135K, GLU135L, GLU139K, GLU139L, GLU50K, GLU50L, GLU57K, GLU57L, GLU65K, GLU65L, GLU72K, GLU72L, GLU78K, GLU78L, GLU83K, GLU83L, GLU85K, GLU85L, GLU91K, GLU91L, ILE126K, ILE126L, ILE128K, ILE128L, ILE49K, ILE49L, ILE80K, ILE80L, LEU104K, LEU104L, LEU108K, LEU108L, LEU115K, LEU115L, LEU129K, LEU129L, LEU133K, LEU133L, LEU137K, LEU137L, LEU143K, LEU143L, LEU144K, LEU144L, LEU147K, LEU55K, LEU55L, LEU62K, LEU62L, LEU66K, LEU66L, LEU76K, LEU76L, LEU86K, LEU86L, LEU97K, LEU97L, LYS123K, LYS123L, LYS131K, LYS131L, LYS140K, LYS140L, LYS37K, LYS37L, LYS56K, LYS56L, LYS63K, LYS63L, LYS74K, LYS74L, LYS82K, LYS89L, LYS99L, PHE109K, PHE109L, SER107K, SER107L, SER38L, SER44K, SER44L, SER67K, SER67L, THR105K, THR105L, THR134K, THR134L, THR41K, THR41L, THR61K, THR61L, THR88K, THR88L, TYR124K, TYR124L, TYR52K, TYR52L, TYR59K, TYR59L, VAL101K, VAL101L, VAL116K, VAL116L, VAL73K, VAL73L
• K-O: ARG120O, PHE109K, PHE109O
• M-N: ALA106M, ALA106N, ALA112M, ALA112N, ALA117M, ALA117N, ALA119M, ALA119N, ALA125M, ALA125N, ALA48M, ALA48N, ALA81N, ALA90M, ALA90N, ALA94M, ALA94N, ARG120M, ARG120N, ARG132M, ARG132N, ARG138M, ARG138N, ARG64M, ARG64N, ARG69M, ARG69N, ARG75M, ARG75N, ARG77M, ARG77N, ARG87M, ARG87N, ASN113M, ASN113N, ASN114N, ASN130M, ASN130N, ASN51M, ASN51N, ASN53M, ASN53N, ASN60M, ASN60N, ASN84M, ASN84N, ASN98M, ASN98N, ASP110M, ASP110N, ASP118M, ASP118N, ASP141M, ASP141N, ASP58M, ASP58N, ASP68M, ASP68N, ASP70M, ASP70N, ASP71M, ASP71N, ASP79M, ASP79N, ASP95N, GLN136M, GLN136N, GLN45M, GLN45N, GLN54M, GLN54N, GLU102M, GLU102N, GLU111M, GLU111N, GLU122M, GLU122N, GLU127M, GLU127N, GLU135M, GLU135N, GLU139M, GLU139N, GLU50M, GLU50N, GLU57M, GLU57N, GLU65M, GLU65N, GLU72M, GLU72N, GLU78M, GLU78N, GLU83M, GLU83N, GLU85M, GLU91M, GLU91N, GLU92M, ILE126M, ILE126N, ILE128M, ILE128N, ILE49M, ILE49N, ILE80M, ILE80N, LEU104M, LEU104N, LEU108M, LEU108N, LEU115M, LEU115N, LEU129M, LEU129N, LEU133M, LEU133N, LEU137M, LEU137N, LEU144M, LEU55M, LEU55N, LEU62M, LEU62N, LEU66M, LEU66N, LEU76M, LEU76N, LEU86N, LEU97N, LYS123M, LYS123N, LYS131M, LYS131N, LYS140M, LYS140N, LYS56M, LYS56N, LYS63M, LYS63N, LYS74M, LYS74N, LYS82N, LYS89M, LYS99M, PHE109M, PHE109N, SER107M, SER107N, SER44M, SER44N, SER67M, SER67N, THR105M, THR105N, THR134M, THR134N, THR41M, THR41N, THR61M, THR61N, THR88M, THR88N, TYR124M, TYR124N, TYR52M, TYR52N, TYR59M, TYR59N, VAL101M, VAL101N, VAL116M, VAL116N, VAL73M, VAL73N
• M-O: ARG120M, GLU111O
• M-P: ASN113M, ASN113P, PHE109M, PHE109P
• N-Q: ASN113N, ASN113Q, PHE109N, PHE109Q
• O-P: ALA106P, ALA112O, ALA112P, ALA117O, ALA117P, ALA119O, ALA119P, ALA125O, ALA125P, ALA47O, ALA47P, ALA48O, ALA48P, ALA81O, ALA81P, ALA90O, ALA90P, ALA94O, ALA94P, ARG120O, ARG120P, ARG132O, ARG132P, ARG138O, ARG138P, ARG64O, ARG64P, ARG69O, ARG69P, ARG75O, ARG75P, ARG77O, ARG77P, ARG87O, ARG87P, ASN113O, ASN113P, ASN130O, ASN130P, ASN51O, ASN51P, ASN53O, ASN53P, ASN60O, ASN60P, ASN84O, ASN84P, ASN98O, ASN98P, ASP110O, ASP118O, ASP118P, ASP141O, ASP141P, ASP145O, ASP58O, ASP58P, ASP68O, ASP68P, ASP70O, ASP70P, ASP71O, ASP71P, ASP79O, ASP79P, GLN136O, GLN136P, GLN45O, GLN45P, GLN54O, GLN54P, GLU102O, GLU111O, GLU111P, GLU122O, GLU122P, GLU127O, GLU127P, GLU135O, GLU135P, GLU139O, GLU139P, GLU50O, GLU50P, GLU57O, GLU57P, GLU65O, GLU65P, GLU72O, GLU72P, GLU78O, GLU78P, GLU83O, GLU83P, GLU85O, GLU85P, GLU91O, GLU91P, ILE126O, ILE126P, ILE128O, ILE128P, ILE49O, ILE49P, ILE80O, ILE80P, LEU104O, LEU104P, LEU108O, LEU108P, LEU115O, LEU115P, LEU129O, LEU129P, LEU133O, LEU133P, LEU137O, LEU137P, LEU143O, LEU143P, LEU144O, LEU144P, LEU147O, LEU151O, LEU55O, LEU55P, LEU62O, LEU62P, LEU66O, LEU66P, LEU76O, LEU76P, LEU86O, LEU86P, LEU97O, LEU97P, LYS123O, LYS123P, LYS131O, LYS131P, LYS140O, LYS140P, LYS37O, LYS37P, LYS56O, LYS56P, LYS63O, LYS63P, LYS74O, LYS74P, LYS82P, PHE109O, PHE109P, SER38P, SER44O, SER44P, SER67O, SER67P, THR105O, THR105P, THR134O, THR134P, THR146O, THR148O, THR41O, THR41P, THR61O, THR61P, THR88O, THR88P, TYR124O, TYR124P, TYR52O, TYR52P, TYR59O, TYR59P, VAL101O, VAL101P, VAL116O, VAL116P, VAL73O, VAL73P
• Q-R: ALA106Q, ALA106R, ALA112Q, ALA112R, ALA117R, ALA119Q, ALA119R, ALA125Q, ALA125R, ALA48Q, ALA48R, ALA81Q, ALA81R, ALA90Q, ALA90R, ALA94Q, ALA94R, ARG120R, ARG132Q, ARG132R, ARG138Q, ARG138R, ARG64Q, ARG64R, ARG69Q, ARG69R, ARG75Q, ARG75R, ARG77Q, ARG77R, ARG87Q, ARG87R, ASN113Q, ASN113R, ASN130Q, ASN130R, ASN51Q, ASN51R, ASN53Q, ASN53R, ASN60Q, ASN60R, ASN84Q, ASN84R, ASN98Q, ASN98R, ASP110Q, ASP110R, ASP118Q, ASP118R, ASP141Q, ASP141R, ASP58Q, ASP58R, ASP68Q, ASP68R, ASP70Q, ASP70R, ASP71Q, ASP71R, ASP79Q, ASP79R, GLN136Q, GLN136R, GLN34Q, GLN34R, GLN45Q, GLN45R, GLN54Q, GLN54R, GLU100Q, GLU102Q, GLU102R, GLU111Q, GLU111R, GLU122Q, GLU122R, GLU127Q, GLU127R, GLU135Q, GLU139Q, GLU139R, GLU50Q, GLU50R, GLU57Q, GLU57R, GLU65Q, GLU65R, GLU72Q, GLU72R, GLU78Q, GLU78R, GLU83Q, GLU83R, GLU85R, GLU91R, ILE126Q, ILE126R, ILE128Q, ILE128R, ILE42Q, ILE49Q, ILE49R, ILE80Q, ILE80R, LEU104Q, LEU104R, LEU108Q, LEU108R, LEU115Q, LEU115R, LEU129Q, LEU129R, LEU133Q, LEU133R, LEU137Q, LEU137R, LEU55Q, LEU55R, LEU62Q, LEU62R, LEU66Q, LEU66R, LEU76Q, LEU76R, LEU86Q, LEU86R, LEU97Q, LYS123Q, LYS123R, LYS131Q, LYS131R, LYS140Q, LYS140R, LYS37Q, LYS37R, LYS40R, LYS56Q, LYS56R, LYS63Q, LYS63R, LYS74Q, LYS74R, LYS89R, PHE109Q, PHE109R, SER107Q, SER107R, SER38Q, SER38R, SER44Q, SER44R, SER67Q, SER67R, THR105Q, THR105R, THR134Q, THR134R, THR41Q, THR41R, THR61Q, THR61R, THR88R, TYR124Q, TYR124R, TYR52Q, TYR52R, TYR59Q, TYR59R, VAL101Q, VAL101R, VAL116Q, VAL116R, VAL73Q, VAL73R
• Q-S: ARG120S, LEU104Q
• R-S: ASN113R, ASN113S, PHE109R, PHE109S
• R-T: ARG120R, GLU111T
• S-T: ALA106T, ALA112S, ALA112T, ALA119S, ALA119T, ALA125S, ALA125T, ALA47T, ALA48S, ALA48T, ALA81S, ALA81T, ALA90S, ALA90T, ALA94S, ALA94T, ARG120S, ARG120T, ARG132S, ARG132T, ARG138S, ARG138T, ARG64S, ARG64T, ARG69S, ARG69T, ARG75S, ARG75T, ARG77S, ARG77T, ARG87S, ARG87T, ASN113S, ASN114T, ASN130S, ASN130T, ASN51S, ASN51T, ASN53S, ASN53T, ASN60S, ASN60T, ASN84S, ASN84T, ASN98S, ASN98T, ASP118S, ASP118T, ASP141S, ASP141T, ASP145S, ASP58S, ASP58T, ASP68S, ASP68T, ASP70S, ASP70T, ASP71S, ASP71T, ASP79S, ASP79T, GLN136S, GLN136T, GLN34S, GLN34T, GLN45S, GLN45T, GLN54S, GLN54T, GLU102S, GLU111T, GLU122S, GLU122T, GLU127S, GLU127T, GLU135S, GLU139S, GLU139T, GLU50T, GLU57S, GLU57T, GLU65S, GLU65T, GLU72S, GLU72T, GLU78S, GLU78T, GLU83S, GLU83T, GLU91S, GLU91T, ILE126S, ILE126T, ILE128S, ILE128T, ILE42S, ILE42T, ILE49S, ILE49T, ILE80S, ILE80T, LEU104S, LEU104T, LEU108S, LEU108T, LEU115S, LEU115T, LEU129S, LEU129T, LEU133S, LEU133T, LEU137S, LEU137T, LEU143T, LEU144S, LEU144T, LEU147S, LEU55S, LEU55T, LEU62S, LEU62T, LEU66S, LEU66T, LEU76S, LEU76T, LEU86T, LEU97T, LYS123S, LYS123T, LYS131S, LYS131T, LYS140S, LYS140T, LYS37S, LYS37T, LYS56S, LYS56T, LYS63S, LYS63T, LYS74S, LYS74T, LYS82T, PHE109S, PHE109T, SER38S, SER38T, SER44S, SER44T, SER67S, SER67T, THR105S, THR105T, THR134S, THR134T, THR41S, THR41T, THR61S, THR61T, THR88S, THR88T, TYR124S, TYR52S, TYR52T, TYR59S, TYR59T, VAL101S, VAL101T, VAL116S, VAL116T, VAL73S, VAL73T