2E5W

crystal structure of spermidine synthase from pyrococcus horikoshii ot3

• Total interactions analyzed: 6
• Total true interactions: 5
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 157
  • Norm. En. per Res.: -4.8232
• Hub Node: A(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-148.3348	-82.7287	-526.181	-757.2445	157	21	9	19671	1	33	35
A-D	-16.9745	-29.7783	-83.1612	-129.914	55	2	0	3626	2	25	23
B-C	-20.0264	-55.1569	-85.7219	-160.9053	55	2	0	3675	4	24	23
B-D	-12.0548	17.8122	-18.3472	-12.5898	36	1	0	1179	3	22	19
C-D	-148.1138	-71.7566	-535.153	-755.0234	159	20	8	19922	2	33	34

Interface residues

• A-B: ALA17A, ALA17B, ALA230A, ALA230B, ARG12A, ARG12B, ARG274A, ARG274B, ASP262A, ASP262B, ASP264A, ASP264B, ASP3A, GLN271A, GLN271B, GLN278A, GLN278B, GLU259A, GLU259B, GLU267A, GLU267B, GLU40A, GLU40B, GLU57A, GLU57B, GLU5A, GLU5B, GLU64A, GLU64B, GLU8A, GLU8B, GLY13A, GLY13B, GLY15A, GLY15B, GLY228A, GLY228B, GLY253A, GLY253B, GLY257A, GLY257B, GLY41A, GLY41B, GLY43A, GLY43B, GLY58A, GLY58B, HIS266A, HIS266B, ILE227A, ILE227B, ILE276A, ILE276B, ILE7A, ILE7B, LEU200A, LEU200B, LEU256A, LEU256B, LEU258A, LEU258B, LEU269A, LEU269B, LEU280A, LEU280B, LEU45A, LYS19A, LYS19B, LYS254A, LYS254B, LYS255A, LYS255B, LYS265A, LYS265B, LYS60A, MET1A, MET246A, MET246B, MET272A, MET272B, MET279B, MET4A, MET4B, PHE18A, PHE18B, PHE224A, PHE224B, PHE235A, PHE235B, PHE270A, PHE270B, PHE42A, PHE42B, PHE6A, PHE6B, PRO11A, PRO11B, PRO225A, PRO225B, PRO232A, PRO232B, PRO263A, PRO263B, PRO273A, PRO273B, PRO65A, PRO65B, SER197B, SER223A, SER223B, SER231A, SER231B, SER61A, SER61B, THR268A, THR268B, THR39A, THR39B, THR56A, TRP233A, TRP233B, TRP9A, TRP9B, TYR10A, TYR10B, TYR14A, TYR14B, TYR199A, TYR199B, TYR221A, TYR221B, TYR222A, TYR222B, TYR229A, TYR229B, TYR260A, TYR260B, TYR261A, TYR261B, TYR275A, TYR275B, TYR62A, TYR62B, VAL16A, VAL16B, VAL198A, VAL198B, VAL20A, VAL20B, VAL226A, VAL226B, VAL277A, VAL277B, VAL52A, VAL52B, VAL55A, VAL55B
• A-D: ALA208D, ALA230D, ALA47D, ARG12D, ARG210D, ARG22A, ARG2A, ASP203D, ASP3A, ASP49D, GLN194D, GLN32D, GLN53D, GLU204D, GLU38A, GLU40A, GLU8D, GLY13D, GLY196D, GLY228D, GLY41A, GLY50D, ILE24A, ILE48D, LEU200D, LEU206D, LEU46D, LEU54D, LYS19A, LYS211D, LYS21A, LYS23A, MET171D, MET1A, MET4A, PHE173D, PHE201D, PHE205D, PHE6D, PRO11D, SER162D, SER197D, THR202D, THR207D, THR39A, THR51D, TRP233D, TRP9D, TYR10D, TYR229D, TYR62D, VAL16D, VAL20A, VAL226D, VAL52D
• B-C: ALA208B, ALA230B, ALA47B, ARG12B, ARG210B, ARG22C, ARG2C, ASP203B, ASP3C, ASP49B, GLN194B, GLN32B, GLN53B, GLU204B, GLU38C, GLU40C, GLU8B, GLY13B, GLY196B, GLY228B, GLY41C, GLY50B, ILE24C, ILE48B, LEU200B, LEU206B, LEU46B, LEU54B, LYS19C, LYS211B, LYS21C, LYS23C, MET171B, MET1C, MET4C, PHE173B, PHE201B, PHE205B, PHE6B, PRO11B, SER162B, SER197B, THR202B, THR207B, THR39C, THR51B, TRP233B, TRP9B, TYR10B, TYR229B, TYR62B, VAL16B, VAL20C, VAL226B, VAL52B
• B-D: ARG12B, ARG12D, ARG22B, ARG22D, GLN28B, GLN28D, GLN32B, GLU26B, GLU26D, GLU30D, GLU35B, GLU35D, GLU5B, GLU5D, GLY13B, GLY13D, GLY50B, ILE7D, LYS23B, LYS23D, LYS33B, LYS33D, MET4B, MET4D, PHE6B, PHE6D, PRO11B, PRO11D, SER29B, SER29D, TRP9B, TRP9D, TYR10B, TYR10D, TYR37B, TYR37D
• C-D: ALA17C, ALA17D, ALA230C, ALA230D, ARG12C, ARG12D, ARG274C, ARG274D, ASP262C, ASP262D, ASP264C, ASP264D, ASP3C, GLN271C, GLN271D, GLN278C, GLN278D, GLU259C, GLU259D, GLU267C, GLU267D, GLU40C, GLU40D, GLU57C, GLU57D, GLU5C, GLU5D, GLU64C, GLU64D, GLU8C, GLU8D, GLY13C, GLY13D, GLY15C, GLY15D, GLY228C, GLY228D, GLY253C, GLY253D, GLY257C, GLY257D, GLY41C, GLY41D, GLY43C, GLY43D, GLY58C, GLY58D, HIS266C, HIS266D, ILE227C, ILE227D, ILE276C, ILE276D, ILE7C, ILE7D, LEU200C, LEU200D, LEU256C, LEU256D, LEU258C, LEU258D, LEU269C, LEU269D, LEU280D, LEU45C, LEU45D, LYS19C, LYS19D, LYS254C, LYS254D, LYS255C, LYS255D, LYS265C, LYS265D, LYS60C, LYS60D, MET1C, MET246C, MET246D, MET272C, MET272D, MET279C, MET279D, MET4C, MET4D, PHE18C, PHE18D, PHE224C, PHE224D, PHE235C, PHE235D, PHE270C, PHE270D, PHE42C, PHE42D, PHE6C, PHE6D, PRO11C, PRO11D, PRO225C, PRO225D, PRO232C, PRO232D, PRO263C, PRO263D, PRO273C, PRO273D, PRO65C, PRO65D, SER223C, SER223D, SER231C, SER231D, SER61C, SER61D, THR268C, THR268D, THR39C, THR39D, THR56C, THR56D, TRP233C, TRP233D, TRP9C, TRP9D, TYR10C, TYR10D, TYR14C, TYR14D, TYR199C, TYR199D, TYR221C, TYR221D, TYR222C, TYR222D, TYR229C, TYR229D, TYR260C, TYR260D, TYR261C, TYR261D, TYR275C, TYR275D, TYR62C, TYR62D, VAL16C, VAL16D, VAL198C, VAL198D, VAL20C, VAL20D, VAL226C, VAL226D, VAL277C, VAL277D, VAL52C, VAL52D, VAL55C, VAL55D