2DWZ

structure of the oncoprotein gankyrin in complex with s6 atpase of the 26s proteasome

• Total interactions analyzed: 6
• Total true interactions: 3
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 113
  • Norm. En. per Res.: -4.5882
• Hub Node: A(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-49.6739	-148.253	-320.54	-518.4669	113	16	7	12325	14	98	73
A-C	-17.9709	-7.6417	-135.916	-161.5285	72	5	2	6435	1	23	31
C-D	-74.2948	-135.6912	-312.093	-522.079	119	20	6	12797	10	100	73

Interface residues

• A-B: ALA113A, ALA114A, ALA140A, ALA146A, ALA147A, ALA148A, ALA179A, ALA365B, ALA386B, ALA396B, ALA50A, ALA72A, ALA80A, ALA81A, ALA83A, ARG118A, ARG145A, ARG184A, ARG338B, ARG339B, ARG342B, ARG366B, ARG388B, ARG391B, ARG41A, ARG85A, ASN103A, ASN105A, ASN12A, ASN151A, ASN173A, ASN353B, ASN390B, ASN7A, ASP136A, ASP169A, ASP181A, ASP337B, ASP359B, ASP362B, ASP368B, ASP37A, ASP398B, ASP39A, ASP70A, ASP71A, CYS107A, CYS180A, CYS48A, CYS4A, GLN104A, GLN340B, GLN38A, GLU171A, GLU182A, GLU183A, GLU204A, GLU356B, GLU357B, GLU361B, GLU389B, GLU400B, GLY106A, GLY150A, GLY172A, GLY51A, GLY73A, GLY84A, HIS111A, HIS137A, HIS144A, HIS45A, HIS78A, ILE393B, ILE79A, LEU178A, LEU354B, LEU360B, LEU395B, LYS116A, LYS149A, LYS203A, LYS213A, LYS341B, LYS369B, LYS397B, LYS401B, LYS404B, MET336B, PHE399B, PRO367B, SER115A, SER16A, SER355B, SER40A, SER49A, SER6A, SER75A, SER82A, THR170A, TRP46A, TRP74A, TYR112A, TYR138A, TYR15A, TYR363B, TYR392B, TYR403B, VAL211A, VAL358B, VAL364B, VAL394B, VAL5A
• A-C: ALA163C, ALA224A, ALA224C, ALA229A, ALA229C, ARG222A, ARG222C, GLN194A, GLN194C, GLU120A, GLU120C, GLU127A, GLU127C, GLU186A, GLU186C, GLU225A, GLU225C, GLU227A, GLU227C, GLU228A, GLU228C, GLY215A, GLY215C, GLY226A, GLY226C, HIS119A, HIS119C, HIS156A, HIS156C, ILE157A, ILE157C, ILE219A, ILE219C, LEU152A, LEU152C, LEU158A, LEU158C, LEU159A, LEU159C, LEU216C, LEU218A, LEU218C, LEU220A, LEU220C, LEU223A, LEU223C, LYS153A, LYS153C, LYS162A, LYS162C, LYS189A, LYS189C, LYS221A, LYS221C, MET154A, MET154C, PHE160A, PHE160C, PHE190A, PHE190C, THR193A, THR193C, TYR161A, TYR161C, VAL123A, VAL123C, VAL155A, VAL155C, VAL185A, VAL185C, VAL192A, VAL192C
• C-D: ALA113C, ALA114C, ALA140C, ALA146C, ALA147C, ALA148C, ALA179C, ALA365D, ALA386D, ALA396D, ALA50C, ALA72C, ALA80C, ALA81C, ALA83C, ARG118C, ARG145C, ARG184C, ARG338D, ARG339D, ARG342D, ARG366D, ARG388D, ARG391D, ARG41C, ARG85C, ASN103C, ASN105C, ASN12C, ASN151C, ASN173C, ASN353D, ASN390D, ASN7C, ASP136C, ASP169C, ASP181C, ASP337D, ASP359D, ASP362D, ASP368D, ASP37C, ASP398D, ASP39C, ASP70C, ASP71C, CYS107C, CYS180C, CYS48C, CYS4C, GLN104C, GLN340D, GLN38C, GLU171C, GLU182C, GLU183C, GLU204C, GLU356D, GLU357D, GLU361D, GLU389D, GLU400D, GLY106C, GLY150C, GLY172C, GLY51C, GLY73C, GLY84C, HIS111C, HIS137C, HIS144C, HIS45C, HIS78C, ILE393D, ILE407D, ILE79C, LEU178C, LEU343D, LEU354D, LEU360D, LEU395D, LYS116C, LYS149C, LYS203C, LYS213C, LYS341D, LYS369D, LYS397D, LYS401D, LYS404D, MET143C, PHE399D, PRO175C, PRO367D, PRO76C, SER115C, SER16C, SER355D, SER40C, SER49C, SER6C, SER75C, SER82C, THR141C, THR170C, THR174C, TRP46C, TRP74C, TYR112C, TYR138C, TYR15C, TYR363D, TYR392D, TYR403D, VAL185C, VAL358D, VAL364D, VAL394D, VAL5C