2DQF

crystal structure of hyhel-10 fv mutant (y33ay53a) complexed with hen egg lysozyme

• Total interactions analyzed: 15
• Total true interactions: 12
• Strongest Interaction:
  • Chains: D-F
  • Int. Res.: 47
  • Norm. En. per Res.: -3.4998
• Hub Node: A(5)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-6.6179	-21.9548	-233.369	-261.9417	81	11	4	8248	1	10	7
A-C	-43.747	0.0	-105.585	-149.332	45	8	0	4125	0	1	7
A-D	-10.0482	0.0	-20.065	-30.1132	15	2	0	729	0	0	0
A-E	-11.4341	-4.2472	-65.6886	-81.3699	37	5	0	2644	2	11	8
A-F	-17.6866	0.0	-67.4612	-85.1478	49	2	0	2896	0	3	2
B-C	-11.6462	-16.0491	-98.9505	-126.6458	44	7	1	3566	2	9	2
B-D	-14.3673	26.8032	-69.3476	-56.9117	38	4	0	2697	2	11	10
C-D	-19.5413	0.0	-62.3077	-81.849	50	1	0	2649	0	3	2
C-F	0.0	9.2617	-29.6548	-20.3931	31	3	0	1175	0	8	5
D-E	-15.3771	-9.5732	-219.486	-244.4362	77	10	4	8062	0	10	7
D-F	-58.0282	0.0	-106.464	-164.4922	47	5	0	4220	0	1	7
E-F	-19.4545	-12.0164	-93.9442	-125.4151	44	6	1	3641	1	8	2

Interface residues

• A-B: ALA33B, ALA96B, ALA9A, ARG38B, ARG44B, ARG45A, ASN43B, ASN60B, ASN97B, ASP101B, ASP1A, ASP99B, CYS88A, CYS95B, GLN105B, GLN37A, GLN38A, GLN3B, GLN6A, GLN89A, GLN90A, GLU42A, GLU46B, GLU6B, GLY100A, GLY100B, GLY101A, GLY104B, GLY106B, GLY42B, GLY49B, GLY99A, HIS34A, HIS41A, ILE37B, ILE55A, ILE67B, ILE69B, LEU45B, LEU46A, LEU47A, LEU4B, LEU63B, LYS103A, LYS39A, LYS39B, LYS49A, MET48B, MET85A, PHE40B, PHE87A, PHE98A, PRO44A, PRO61B, PRO95A, SER35B, SER40A, SER43A, SER56A, SER62B, SER91A, THR102A, THR107B, THR10A, THR57B, THR92B, THR97A, TRP103B, TRP36B, TRP94A, TRP98B, TYR102B, TYR36A, TYR47B, TYR50A, TYR50B, TYR58B, TYR59B, TYR86A, TYR94B, TYR96A
• A-C: ALA11C, ALA90C, ALA95C, ARG14C, ARG21C, ASN19C, ASN31A, ASN32A, ASN77C, ASN92A, ASN93C, ASP18C, CYS94C, GLN27A, GLN53A, GLN90A, GLY16C, GLY22C, GLY30A, GLY68A, HIS15C, HIS34A, ILE29A, ILE2A, LEU17C, LEU33A, LYS13C, LYS49A, LYS96C, LYS97C, MET12C, PRO95A, SER100C, SER28A, SER67A, SER91A, SER93A, THR89C, TRP94A, TYR20C, TYR23C, TYR50A, TYR96A, VAL92C, VAL99C
• A-D: GLN53A, GLY57A, GLY57D, ILE55A, ILE55D, ILE58A, ILE58D, LEU46A, LEU46D, LYS49A, LYS49D, SER54A, SER54D, SER56A, SER56D
• A-E: ALA33E, ALA53E, ARG45A, ARG61A, ASN76E, ASN97E, ASP101E, ASP1E, ASP27E, ASP32E, ASP82A, ASP99E, GLN37A, GLN3E, GLU42A, GLU79A, GLU81A, GLY100E, GLY26E, GLY57A, ILE29E, ILE55A, ILE58A, LEU47A, LYS39A, PHE62A, PRO59A, SER28E, SER31E, SER56A, SER60A, SER77A, THR25E, THR80A, TYR102E, VAL24E, VAL2E
• A-F: ALA51A, ALA82F, ARG61A, ARG61F, ARG68F, ARG73F, ASN65F, ASN74F, ASN76A, ASN77F, ASP66F, CYS64F, CYS76F, CYS80F, GLN53A, GLY57A, GLY64A, GLY66A, GLY67F, GLY71F, ILE48A, ILE55A, ILE58A, ILE75A, ILE78F, LEU75F, LYS49A, LYS97F, PHE62A, PRO59A, PRO70F, PRO79F, SER18A, SER20A, SER52A, SER54A, SER56A, SER60A, SER63A, SER65A, SER72F, SER74A, SER77A, SER81F, THR69F, THR72A, TRP62F, TRP63F, TYR50A
• B-C: ALA33B, ALA53B, ALA95C, ARG21C, ARG71B, ARG73C, ASN103C, ASN74C, ASN77C, ASN93C, ASN97B, ASP101B, ASP101C, ASP32B, ASP99B, CYS76C, CYS94C, GLY102C, GLY104C, GLY55B, ILE29B, ILE98C, LEU75C, LYS96C, LYS97C, SER100C, SER28B, SER31B, SER52B, SER54B, SER56B, THR30B, THR57B, TRP62C, TRP63C, TRP98B, TYR102B, TYR20C, TYR23C, TYR50B, TYR58B, TYR59B, VAL51B, VAL99C
• B-D: ALA53B, ARG45D, ARG61D, ASN76B, ASN97B, ASP101B, ASP1B, ASP27B, ASP32B, ASP82D, ASP99B, GLN37D, GLN3B, GLU42D, GLU79D, GLU81D, GLY26B, GLY57D, ILE29B, ILE55D, ILE58D, LEU47D, LYS39D, PHE62D, PHE83D, PRO59D, SER28B, SER31B, SER56D, SER60D, SER77D, THR25B, THR80D, TRP34B, TYR102B, TYR86D, VAL24B, VAL2B
• C-D: ALA51D, ALA82C, ARG61C, ARG61D, ARG68C, ARG73C, ASN65C, ASN74C, ASN76D, ASN77C, ASP66C, CYS64C, CYS76C, CYS80C, GLN53D, GLY57D, GLY64D, GLY66D, GLY67C, GLY71C, ILE48D, ILE55D, ILE58D, ILE75D, ILE78C, LEU75C, LYS49D, LYS97C, PHE62D, PRO59D, PRO70C, PRO79C, SER18D, SER20D, SER52D, SER54D, SER56D, SER60C, SER60D, SER63D, SER65D, SER72C, SER74D, SER77D, SER81C, THR69C, THR72D, TRP62C, TRP63C, TYR50D
• C-F: ALA82C, ALA82F, ALA90F, ARG14C, ARG14F, ASP87C, ASP87F, GLN41C, GLN41F, GLU7F, HIS15C, HIS15F, ILE78F, ILE88C, ILE88F, LEU84C, LEU84F, LYS1C, LYS1F, PHE3C, PHE3F, SER81C, SER81F, SER85C, SER85F, SER86C, SER86F, THR40C, THR40F, THR89C, THR89F
• D-E: ALA33E, ALA96E, ARG38E, ARG44E, ARG45D, ASN43E, ASN60E, ASN97E, ASP101E, ASP1D, ASP99E, CYS88D, CYS95E, GLN105E, GLN38D, GLN6D, GLN89D, GLN90D, GLU42D, GLU46E, GLU6E, GLY100D, GLY100E, GLY101D, GLY104E, GLY106E, GLY42E, GLY49E, GLY99D, HIS34D, HIS41D, ILE37E, ILE55D, ILE67E, ILE69E, LEU108E, LEU45E, LEU46D, LEU47D, LEU4E, LEU63E, LYS103D, LYS39D, LYS39E, LYS49D, MET48E, MET85D, PHE87D, PHE98D, PRO44D, PRO61E, PRO95D, SER35E, SER40D, SER43D, SER56D, SER62E, SER91D, THR102D, THR57E, THR92E, THR97D, TRP103E, TRP36E, TRP94D, TRP98E, TYR102E, TYR36D, TYR47E, TYR50D, TYR50E, TYR58E, TYR59E, TYR86D, TYR94E, TYR96D, VAL51E
• D-F: ALA11F, ALA90F, ALA95F, ARG14F, ARG21F, ASN19F, ASN31D, ASN32D, ASN77F, ASN92D, ASN93F, ASP18F, CYS76F, CYS94F, GLN27D, GLN53D, GLN90D, GLY16F, GLY22F, GLY30D, GLY68D, HIS15F, HIS34D, ILE29D, ILE2D, ILE78F, LEU17F, LEU33D, LYS13F, LYS49D, LYS96F, LYS97F, MET12F, PRO95D, SER100F, SER28D, SER67D, SER91D, SER93D, THR89F, TRP94D, TYR20F, TYR23F, TYR50D, TYR96D, VAL92F, VAL99F
• E-F: ALA33E, ALA53E, ALA95F, ARG21F, ARG71E, ARG73F, ASN103F, ASN74F, ASN77F, ASN93F, ASN97E, ASP101E, ASP101F, ASP32E, ASP99E, CYS76F, CYS94F, GLY102F, GLY104F, GLY55E, ILE98F, LEU75F, LYS96F, LYS97F, SER100F, SER28E, SER31E, SER52E, SER54E, SER56E, SER72F, THR30E, THR57E, TRP62F, TRP63F, TRP98E, TYR102E, TYR20F, TYR23F, TYR50E, TYR58E, TYR59E, VAL51E, VAL99F