2DOI

the x-ray crystallographic structure of the angiogenesis inhibitor, angiostatin, bound to a peptide from the group a streptococcus protein pam

• Total interactions analyzed: 6
• Total true interactions: 3
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 51
  • Norm. En. per Res.: -6.7662
• Hub Node: X(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
X-C	-9.8467	-108.8244	-106.08	-224.7511	50	17	2	5660	5	37	43
X-A	-30.9632	-74.8898	-187.277	-293.13	86	36	0	8597	4	53	42
A-B	-13.0802	-168.0038	-163.991	-345.075	51	17	3	6615	10	37	47

Interface residues

• X-C: ALA197X, ALA306C, ALA321C, ARG216X, ARG220X, ARG223X, ARG234X, ARG312C, ARG317C, ARG325C, ASN207X, ASN217X, ASN232X, ASN315C, ASP219X, ASP307C, CYS226X, GLN311C, GLU172X, GLU221X, GLU236X, GLU309C, GLU316C, GLU319C, GLU320C, GLU322C, GLU324C, GLY199X, HIS198X, HIS318C, ILE201X, LEU210X, LEU222X, LEU237X, LEU310C, LEU313C, LYS204X, LYS208X, LYS233X, LYS314C, PHE205X, PHE227X, PRO206X, PRO218X, PRO224X, THR305C, TRP190X, TRP225X, TRP235X, TYR200X
• X-A: ARG115A, ARG117A, ARG153A, ARG242X, ASN101A, ASN135A, ASN135X, ASN138A, ASN213X, ASN88X, ASN91X, ASP137A, ASP139A, ASP139X, ASP149A, ASP155A, ASP158X, ASP175X, ASP239X, CYS145A, CYS162X, CYS166X, CYS187X, CYS215X, CYS238X, CYS243X, GLN141A, GLN141X, GLU151A, GLU161X, GLU163X, GLU164X, GLU165X, GLU186X, GLY142A, GLY142X, GLY176X, GLY184X, GLY87X, GLY89X, HIS114A, HIS123A, HIS168X, ILE103A, ILE159X, ILE178X, ILE240X, LEU160X, LYS100A, LYS152A, LYS177X, LYS180X, LYS211X, LYS212X, LYS85A, LYS85X, LYS90X, MET167X, MET182X, PHE118A, PRO113A, PRO116A, PRO136A, PRO140A, PRO140X, PRO143X, PRO150A, PRO241X, SER112A, SER179X, THR111A, THR122A, THR147A, THR181X, THR244X, THR245X, THR86X, THR99A, TRP108A, TRP144A, TYR146A, TYR154A, TYR156A, TYR156X, TYR174X, TYR214X
• A-B: ALA306B, ALA308B, ALA321B, ARG216A, ARG220A, ARG223A, ARG234A, ARG312B, ARG317B, ARG325B, ASN207A, ASN217A, ASN232A, ASN315B, ASP219A, ASP307B, CYS226A, GLN311B, GLU221A, GLU236A, GLU309B, GLU316B, GLU319B, GLU320B, GLU322B, GLU324B, GLY199A, HIS196A, HIS198A, HIS318B, ILE201A, LEU210A, LEU222A, LEU237A, LEU304B, LEU310B, LEU313B, LYS204A, LYS208A, LYS233A, LYS314B, PHE205A, PHE227A, PRO206A, PRO218A, PRO224A, THR305B, TRP190A, TRP225A, TRP235A, TYR200A