2DHR

whole cytosolic region of atp-dependent metalloprotease ftsh (g399l)

• Total interactions analyzed: 15
• Total true interactions: 9
• Strongest Interaction:
  • Chains: A-F
  • Int. Res.: 243
  • Norm. En. per Res.: -3.0195
• Hub Node: A(4)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-62.177	-20.7567	-274.753	-357.6866	170	36	5	14863	7	122	98
A-C	0.0	28.2421	-20.8908	7.3513	35	2	0	1124	0	6	11
A-E	0.0	32.0056	-21.6613	10.3443	33	1	0	1158	0	6	11
A-F	-128.2393	-148.7712	-456.723	-733.7335	243	56	14	21792	11	136	122
B-C	-125.8002	-148.0405	-454.017	-727.8577	248	60	12	21688	9	140	123
C-D	-39.9127	-31.4376	-291.957	-363.3073	166	37	5	14513	5	114	93
C-E	0.0	28.2632	-24.5467	3.7165	36	2	0	1227	0	7	10
D-E	-116.4392	-132.7661	-448.046	-697.2513	246	53	12	21489	8	139	125
E-F	-55.9905	-8.5712	-257.991	-322.5528	157	35	4	13614	5	110	83

Interface residues

• A-B: ALA186A, ALA259B, ALA416B, ALA446B, ALA477B, ALA490B, ALA497B, ALA501B, ALA518A, ALA520A, ALA540A, ALA540B, ALA546B, ARG187A, ARG238A, ARG262B, ARG275B, ARG303B, ARG313A, ARG316A, ARG319A, ARG410B, ARG412B, ARG413B, ARG443B, ARG454A, ARG454B, ARG462A, ARG464A, ARG476B, ARG495B, ARG502B, ARG503A, ARG522A, ARG533A, ARG533B, ARG542A, ARG542B, ARG548B, ARG549B, ASN272B, ASN302B, ASN492B, ASP224B, ASP255B, ASP258B, ASP273B, ASP287A, ASP292A, ASP305B, ASP318A, ASP411B, ASP433A, ASP456A, ASP484B, ASP485B, ASP493B, ASP524A, ASP531B, ASP544B, GLN281A, GLN496B, GLN534A, GLN554B, GLN556B, GLU167A, GLU170A, GLU227B, GLU242A, GLU256B, GLU274B, GLU285A, GLU290A, GLU479B, GLU480B, GLU491B, GLU499B, GLU507A, GLU513A, GLU523A, GLU537A, GLU537B, GLU538A, GLU538B, GLU545B, GLU552B, GLU553B, GLY222B, GLY288A, GLY315A, GLY489B, GLY509A, GLY515A, HIS182A, HIS418B, HIS459A, HIS511A, ILE188A, ILE306B, ILE414B, ILE440B, ILE469B, ILE543B, ILE551B, LEU399B, LEU405B, LEU407B, LEU458A, LEU465A, LEU466A, LEU473B, LEU527A, LEU550B, LYS190A, LYS245A, LYS263B, LYS291A, LYS402B, LYS403B, LYS463A, LYS541A, LYS541B, MET228B, MET286A, MET450B, MET457A, MET510A, PHE181A, PHE289A, PHE483B, PHE494B, PHE514A, PRO189A, PRO198B, PRO314A, PRO442B, PRO512A, PRO516A, SER221B, SER223B, SER404B, SER408B, SER461A, SER536A, SER536B, THR293A, THR415B, THR487B, THR488B, THR498B, THR506A, THR525A, THR539A, THR539B, TRP460A, TRP508A, TYR519A, TYR526A, TYR530B, TYR535A, TYR535B, TYR555B, VAL226B, VAL260B, VAL284A, VAL406B, VAL486B, VAL517A, VAL521A, VAL547B
• A-C: ALA234A, ARG238A, ARG264A, ARG275A, ASN272A, ASN272C, ASN280A, ASP273A, ASP273C, GLN277A, GLN277C, GLN281A, GLU227C, GLU274C, GLU276A, GLU537A, GLU537C, GLY231A, GLY231C, GLY265A, GLY267C, GLY269C, GLY270C, GLY271C, LEU279A, LEU527A, LYS263A, PHE229C, THR278A, VAL230A, VAL230C, VAL232C, VAL268A, VAL268C, VAL284A
• A-E: ALA234E, ARG264E, ASN272A, ASN272E, ASN280E, ASP273A, ASP273E, GLN277A, GLN277E, GLN281E, GLU227A, GLU274A, GLU276E, GLU537A, GLU537E, GLY231A, GLY231E, GLY265E, GLY267A, GLY269A, GLY270A, GLY271A, LEU279E, LEU527E, LYS263E, PHE229A, THR278E, TYR530E, VAL230A, VAL230E, VAL268A, VAL268E, VAL284E
• A-F: ALA144A, ALA186F, ALA220A, ALA259A, ALA310F, ALA322F, ALA339A, ALA363A, ALA372A, ALA373A, ALA376A, ALA377A, ALA401A, ALA477A, ALA490A, ALA497A, ALA501A, ALA518F, ALA520F, ALA540A, ALA540F, ALA546A, ARG143A, ARG145A, ARG180F, ARG187F, ARG207A, ARG236A, ARG262A, ARG262F, ARG264A, ARG275A, ARG303A, ARG313F, ARG316F, ARG319F, ARG340A, ARG378A, ARG381A, ARG382A, ARG395A, ARG410A, ARG443A, ARG445F, ARG453F, ARG462F, ARG464F, ARG476A, ARG495A, ARG502A, ARG503F, ARG522F, ARG533A, ARG533F, ARG542A, ARG542F, ARG548A, ARG549A, ASN177F, ASN272F, ASN280F, ASN302A, ASN367A, ASN370A, ASN492A, ASP224A, ASP255A, ASP258A, ASP287F, ASP308F, ASP318F, ASP411A, ASP433F, ASP456F, ASP484A, ASP485A, ASP493A, ASP524F, ASP531F, ASP544A, GLN320F, GLN468F, GLN496A, GLN534F, GLN554A, GLN556A, GLU166F, GLU167F, GLU170F, GLU173F, GLU183F, GLU227A, GLU256A, GLU276F, GLU366A, GLU371A, GLU379A, GLU455F, GLU479A, GLU480A, GLU491A, GLU499A, GLU507F, GLU513F, GLU523F, GLU537A, GLU537F, GLU538A, GLU538F, GLU545A, GLU552A, GLU553A, GLY185F, GLY222A, GLY261A, GLY265A, GLY267A, GLY288F, GLY315F, GLY341A, GLY380A, GLY448F, GLY489A, GLY509F, GLY515F, GLY528F, GLY529F, HIS182F, HIS436F, HIS459F, HIS511F, ILE171F, ILE188F, ILE257A, ILE306A, ILE384A, ILE414A, ILE469A, ILE543A, ILE543F, ILE551A, LEU168F, LEU279F, LEU283F, LEU307A, LEU307F, LEU369A, LEU374A, LEU375A, LEU399A, LEU405A, LEU407A, LEU447F, LEU458F, LEU465F, LEU466F, LEU473A, LEU527F, LEU550A, LYS152A, LYS165F, LYS169F, LYS190F, LYS202A, LYS263A, LYS263F, LYS291F, LYS342A, LYS383A, LYS402A, LYS403A, LYS437F, LYS463F, LYS541A, LYS541F, LYS559A, MET184F, MET228A, MET286F, MET450F, MET451F, MET457F, MET504F, MET510F, PHE155F, PHE174F, PHE181F, PHE225A, PHE229A, PHE483A, PHE494A, PHE514F, PRO178F, PRO189F, PRO198A, PRO304F, PRO309F, PRO314F, PRO343A, PRO400A, PRO452F, PRO512F, PRO516F, SER179F, SER221A, SER223A, SER266A, SER404A, SER408A, SER461F, SER536A, SER536F, THR219A, THR301A, THR415A, THR487A, THR488A, THR498A, THR525F, THR539A, THR539F, TRP460F, TRP508F, TYR519F, TYR526F, TYR530F, TYR535A, TYR535F, TYR555A, VAL172F, VAL195F, VAL226A, VAL232A, VAL260A, VAL284F, VAL406A, VAL435F, VAL486A, VAL517F, VAL521F, VAL532A, VAL532F, VAL547A
• B-C: ALA144C, ALA186B, ALA220C, ALA259C, ALA300C, ALA310B, ALA322B, ALA339C, ALA372C, ALA373C, ALA376C, ALA377C, ALA401C, ALA477C, ALA490C, ALA497C, ALA501C, ALA518B, ALA520B, ALA540B, ALA540C, ALA546C, ARG143C, ARG145C, ARG180B, ARG187B, ARG207C, ARG236C, ARG262C, ARG264C, ARG275C, ARG303C, ARG313B, ARG316B, ARG319B, ARG340C, ARG378C, ARG381C, ARG382C, ARG395C, ARG410C, ARG443C, ARG445B, ARG453B, ARG454B, ARG462B, ARG464B, ARG476C, ARG495C, ARG502C, ARG503B, ARG522B, ARG533B, ARG533C, ARG542B, ARG542C, ARG548C, ARG549C, ASN177B, ASN272B, ASN280B, ASN302C, ASN367C, ASN370C, ASN492C, ASP224C, ASP255C, ASP258C, ASP287B, ASP308B, ASP318B, ASP411C, ASP433B, ASP456B, ASP484C, ASP485C, ASP493C, ASP524B, ASP531B, ASP531C, ASP544C, GLN320B, GLN468B, GLN496C, GLN534B, GLN554C, GLN556C, GLU166B, GLU167B, GLU170B, GLU173B, GLU183B, GLU227C, GLU256C, GLU276B, GLU366C, GLU371C, GLU379C, GLU455B, GLU479C, GLU480C, GLU491C, GLU499C, GLU507B, GLU513B, GLU523B, GLU537B, GLU537C, GLU538B, GLU538C, GLU545C, GLU552C, GLU553C, GLY185B, GLY222C, GLY261C, GLY265C, GLY267C, GLY288B, GLY315B, GLY341C, GLY380C, GLY434B, GLY448B, GLY489C, GLY509B, GLY515B, GLY528B, HIS182B, HIS338C, HIS436B, HIS459B, HIS511B, ILE171B, ILE188B, ILE257C, ILE306C, ILE384C, ILE414C, ILE469C, ILE543B, ILE543C, ILE551C, LEU147C, LEU168B, LEU279B, LEU283B, LEU307B, LEU307C, LEU311B, LEU369C, LEU374C, LEU375C, LEU399C, LEU405C, LEU407C, LEU447B, LEU458B, LEU465B, LEU466B, LEU473C, LEU500C, LEU527B, LEU550C, LYS152C, LYS165B, LYS169B, LYS190B, LYS202C, LYS263B, LYS291B, LYS342C, LYS383C, LYS402C, LYS403C, LYS437B, LYS463B, LYS541B, LYS541C, LYS559C, MET184B, MET228C, MET286B, MET450B, MET451B, MET457B, MET504B, MET510B, PHE174B, PHE181B, PHE225C, PHE229C, PHE289B, PHE483C, PHE494C, PHE514B, PRO178B, PRO189B, PRO198C, PRO309B, PRO314B, PRO343C, PRO400C, PRO452B, PRO512B, PRO516B, SER179B, SER221C, SER223C, SER266C, SER404C, SER408C, SER461B, SER536B, SER536C, THR203C, THR219C, THR301C, THR415C, THR487C, THR488C, THR498C, THR525B, THR539B, THR539C, TRP460B, TRP508B, TYR519B, TYR526B, TYR530B, TYR535B, TYR535C, TYR555C, VAL146C, VAL172B, VAL195B, VAL226C, VAL232C, VAL260C, VAL284B, VAL406C, VAL435B, VAL486C, VAL517B, VAL521B, VAL532B, VAL532C, VAL547C
• C-D: ALA259D, ALA416D, ALA446D, ALA477D, ALA490D, ALA497D, ALA501D, ALA518C, ALA520C, ALA540C, ALA540D, ALA546D, ARG187C, ARG238C, ARG262D, ARG275D, ARG303D, ARG313C, ARG316C, ARG319C, ARG410D, ARG412D, ARG413D, ARG443D, ARG454C, ARG454D, ARG462C, ARG464C, ARG476D, ARG495D, ARG502D, ARG503C, ARG522C, ARG533C, ARG533D, ARG542C, ARG542D, ARG548D, ARG549D, ASN272D, ASN302D, ASN492D, ASP224D, ASP258D, ASP287C, ASP292C, ASP305D, ASP318C, ASP411D, ASP433C, ASP456C, ASP484D, ASP485D, ASP493D, ASP524C, ASP531D, ASP544D, GLN281C, GLN320C, GLN496D, GLN534C, GLN554D, GLN556D, GLU167C, GLU170C, GLU227D, GLU256D, GLU274D, GLU285C, GLU290C, GLU455C, GLU479D, GLU480D, GLU491D, GLU499D, GLU507C, GLU513C, GLU523C, GLU537C, GLU537D, GLU538C, GLU538D, GLU545D, GLU552D, GLU553D, GLY222D, GLY288C, GLY315C, GLY489D, GLY509C, GLY515C, HIS182C, HIS418D, HIS459C, HIS511C, ILE188C, ILE306D, ILE414D, ILE440D, ILE543D, ILE551D, LEU283C, LEU405D, LEU407D, LEU447D, LEU458C, LEU465C, LEU466C, LEU473D, LEU527C, LEU550D, LYS190C, LYS245C, LYS263D, LYS291C, LYS402D, LYS403D, LYS463C, LYS541C, LYS541D, MET228D, MET450D, MET457C, MET510C, PHE225D, PHE289C, PHE494D, PHE514C, PRO189C, PRO198D, PRO314C, PRO442D, PRO512C, PRO516C, SER221D, SER223D, SER404D, SER408D, SER461C, SER536C, SER536D, THR293C, THR415D, THR487D, THR488D, THR498D, THR506C, THR525C, THR539C, THR539D, TRP460C, TRP508C, TYR519C, TYR526C, TYR530D, TYR535C, TYR535D, TYR555D, VAL226D, VAL260D, VAL284C, VAL406D, VAL486D, VAL517C, VAL521C, VAL547D
• C-E: ALA234C, ARG264C, ARG275C, ASN272C, ASN272E, ASN280C, ASP273C, ASP273E, GLN277C, GLN277E, GLN281C, GLU227E, GLU274E, GLU276C, GLU537C, GLU537E, GLY231C, GLY231E, GLY265C, GLY267E, GLY269E, GLY270E, GLY271E, LEU279C, LEU283C, LEU527C, LYS263C, MET228E, PHE229E, THR278C, VAL230C, VAL230E, VAL268C, VAL268E, VAL284C, VAL532C
• D-E: ALA144E, ALA186D, ALA220E, ALA259E, ALA300E, ALA310D, ALA322D, ALA339E, ALA373E, ALA376E, ALA377E, ALA401E, ALA426D, ALA477E, ALA490E, ALA497E, ALA501E, ALA518D, ALA520D, ALA540D, ALA540E, ALA546E, ARG143E, ARG145E, ARG180D, ARG187D, ARG207E, ARG236E, ARG262E, ARG264E, ARG275E, ARG303E, ARG313D, ARG316D, ARG319D, ARG340E, ARG378E, ARG381E, ARG382E, ARG395E, ARG410E, ARG443E, ARG445D, ARG453D, ARG462D, ARG464D, ARG476E, ARG495E, ARG502E, ARG503D, ARG522D, ARG533D, ARG533E, ARG542D, ARG542E, ARG548E, ARG549E, ASN177D, ASN272D, ASN280D, ASN302E, ASN367E, ASN370E, ASN492E, ASP224E, ASP255E, ASP258E, ASP287D, ASP308D, ASP318D, ASP411E, ASP433D, ASP456D, ASP484E, ASP485E, ASP493E, ASP524D, ASP531D, ASP544E, GLN320D, GLN468D, GLN496E, GLN534D, GLN554E, GLN556E, GLU166D, GLU167D, GLU170D, GLU173D, GLU183D, GLU227E, GLU256E, GLU276D, GLU366E, GLU371E, GLU379E, GLU455D, GLU479E, GLU480E, GLU491E, GLU499E, GLU507D, GLU513D, GLU523D, GLU537D, GLU537E, GLU538D, GLU538E, GLU545E, GLU552E, GLU553E, GLY185D, GLY199E, GLY222E, GLY261E, GLY265E, GLY267E, GLY288D, GLY315D, GLY341E, GLY380E, GLY434D, GLY448D, GLY489E, GLY509D, GLY515D, GLY528D, HIS182D, HIS338E, HIS436D, HIS459D, HIS511D, ILE171D, ILE188D, ILE257E, ILE306E, ILE384E, ILE414E, ILE543D, ILE543E, ILE551E, LEU147E, LEU168D, LEU279D, LEU283D, LEU307D, LEU307E, LEU311D, LEU369E, LEU374E, LEU375E, LEU399E, LEU405E, LEU407E, LEU447D, LEU458D, LEU465D, LEU466D, LEU473E, LEU500E, LEU527D, LEU550E, LYS152E, LYS165D, LYS169D, LYS202E, LYS263D, LYS291D, LYS342E, LYS383E, LYS402E, LYS403E, LYS437D, LYS463D, LYS541D, LYS541E, LYS559E, MET184D, MET228E, MET286D, MET450D, MET451D, MET457D, MET504D, MET510D, PHE155D, PHE174D, PHE181D, PHE225E, PHE229E, PHE449D, PHE483E, PHE494E, PHE514D, PRO189D, PRO197E, PRO198E, PRO309D, PRO314D, PRO343E, PRO400E, PRO452D, PRO512D, PRO516D, SER221E, SER223E, SER266E, SER404E, SER408E, SER461D, SER536D, SER536E, THR203E, THR219E, THR301E, THR415E, THR487E, THR488E, THR498E, THR506D, THR525D, THR539D, THR539E, TRP460D, TRP508D, TYR519D, TYR526D, TYR530D, TYR535D, TYR535E, TYR555E, VAL146E, VAL172D, VAL195D, VAL226E, VAL232E, VAL260E, VAL284D, VAL406E, VAL435D, VAL486E, VAL517D, VAL521D, VAL532D, VAL532E, VAL547E
• E-F: ALA186E, ALA259F, ALA416F, ALA446F, ALA477F, ALA490F, ALA497F, ALA501F, ALA518E, ALA520E, ALA540E, ALA540F, ALA546F, ARG187E, ARG238E, ARG262F, ARG275F, ARG303F, ARG313E, ARG316E, ARG319E, ARG410F, ARG412F, ARG413F, ARG443F, ARG454E, ARG454F, ARG462E, ARG464E, ARG476F, ARG495F, ARG502F, ARG503E, ARG522E, ARG533E, ARG533F, ARG542E, ARG542F, ARG548F, ARG549F, ASN272F, ASN492F, ASP224F, ASP287E, ASP292E, ASP305F, ASP318E, ASP411F, ASP433E, ASP456E, ASP484F, ASP485F, ASP493F, ASP524E, ASP531F, ASP544F, GLN281E, GLN496F, GLN534E, GLN554F, GLN556F, GLU167E, GLU170E, GLU227F, GLU256F, GLU274F, GLU285E, GLU290E, GLU455E, GLU479F, GLU480F, GLU491F, GLU499F, GLU507E, GLU513E, GLU523E, GLU537E, GLU537F, GLU538E, GLU538F, GLU545F, GLU552F, GLU553F, GLY288E, GLY315E, GLY489F, GLY509E, GLY515E, HIS418F, HIS459E, HIS511E, ILE188E, ILE306F, ILE414F, ILE440F, ILE543F, ILE551F, LEU405F, LEU407F, LEU447F, LEU458E, LEU465E, LEU466E, LEU473F, LEU527E, LEU550F, LYS245E, LYS263F, LYS291E, LYS402F, LYS403F, LYS463E, LYS541E, LYS541F, MET450F, MET457E, MET510E, PHE494F, PHE514E, PRO189E, PRO198F, PRO314E, PRO442F, PRO512E, PRO516E, SER221F, SER223F, SER404F, SER408F, SER461E, SER536E, SER536F, THR293E, THR415F, THR487F, THR488F, THR498F, THR506E, THR525E, THR539E, THR539F, TRP460E, TRP508E, TYR519E, TYR526E, TYR530F, TYR535E, TYR535F, TYR555F, VAL226F, VAL260F, VAL284E, VAL406F, VAL486F, VAL517E, VAL521E, VAL547F