2DG2

crystal structure of mouse apolipoprotein a-i binding protein

• Total interactions analyzed: 15
• Total true interactions: 9
• Strongest Interaction:
  • Chains: C-D
  • Int. Res.: 140
  • Norm. En. per Res.: -2.4287
• Hub Node: C(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	0.0	17.4701	-62.9918	-45.5217	52	1	0	2438	3	10	14
A-C	0.0	20.4385	-65.428	-44.9894	50	0	0	2480	4	10	14
B-C	0.0	21.0135	-58.9685	-37.955	52	0	0	2335	3	9	14
C-D	-32.6874	4.3844	-311.708	-340.011	140	6	0	13815	0	36	26
C-E	0.0	-2.4241	-5.2002	-7.6243	15	0	0	475	0	2	5
C-F	0.0	17.9547	-19.7791	-1.8244	15	3	0	846	0	2	4
D-E	-12.3775	-10.2091	-89.7456	-112.3322	68	4	0	4927	4	8	18
D-F	0.0	-2.3331	-4.4617	-6.7948	15	0	0	433	0	2	5
E-F	-28.8873	5.3711	-309.195	-332.7113	139	4	0	13827	0	36	26

Interface residues

• A-B: ARG167B, ARG224A, ARG256A, ASN199B, ASP147A, ASP165B, ASP206A, GLN204A, GLU142B, GLU148A, GLU168B, GLY179A, GLY179B, GLY202A, GLY202B, GLY223A, HIS171B, HIS220A, ILE173B, ILE184A, LEU174B, LEU177B, LEU180A, LEU180B, PHE170B, PHE221A, PRO140B, PRO141B, PRO143A, PRO143B, PRO169B, PRO183A, PRO200A, PRO200B, PRO205A, SER172B, SER175B, SER178A, SER178B, SER201A, SER201B, SER73A, SER75A, THR181A, THR222A, TRP193A, TYR225A, TYR69A, VAL146A, VAL166B, VAL176B, VAL182A
• A-C: ARG167A, ARG224C, ARG256C, ASN199A, ASP147C, ASP165A, ASP206C, GLN204C, GLU142A, GLU148C, GLU168A, GLY179A, GLY179C, GLY202A, GLY223C, HIS171A, HIS220C, ILE173A, ILE184C, LEU174A, LEU177A, LEU180A, LEU180C, PHE170A, PHE221C, PRO140A, PRO141A, PRO143A, PRO143C, PRO169A, PRO183C, PRO200A, PRO200C, PRO205C, SER172A, SER175A, SER178A, SER178C, SER201A, SER73C, SER75C, THR181C, THR222C, TRP193C, TYR225C, TYR69C, VAL146C, VAL166A, VAL176A, VAL182C
• B-C: ARG167C, ARG224B, ARG256B, ASN199B, ASN199C, ASP147B, ASP165C, ASP206B, GLN204B, GLU142C, GLU148B, GLU168C, GLY179B, GLY179C, GLY202B, GLY202C, GLY223B, HIS171C, HIS220B, ILE173C, ILE184B, LEU174C, LEU177C, LEU180B, LEU180C, PHE170C, PHE221B, PRO140C, PRO141C, PRO143B, PRO143C, PRO169C, PRO183B, PRO200B, PRO200C, PRO205B, SER172C, SER175C, SER178B, SER178C, SER201B, SER201C, SER73B, THR181B, THR222B, TRP193B, TYR225B, TYR69B, VAL146B, VAL166C, VAL176C, VAL182B
• C-D: ALA236C, ALA236D, ALA57C, ALA57D, ALA62C, ALA62D, ALA64C, ALA64D, ALA66C, ALA66D, ALA68C, ALA68D, ARG231C, ARG231D, ARG99C, ARG99D, ASN44C, ASN44D, ASP132C, ASP132D, ASP250C, ASP250D, ASP51C, ASP51D, CYS128C, CYS128D, CYS253C, CYS253D, GLN127C, GLN127D, GLN129C, GLN129D, GLN47C, GLN47D, GLN52C, GLN52D, GLU238C, GLU238D, GLU252C, GLU252D, GLU41C, GLU41D, GLU45C, GLU45D, GLU55C, GLU55D, GLY105C, GLY105D, GLY123C, GLY123D, GLY230C, GLY230D, HIS100C, HIS100D, ILE133C, ILE133D, ILE65C, ILE65D, LEU101C, LEU101D, LEU103C, LEU103D, LEU120C, LEU120D, LEU124C, LEU124D, LEU237C, LEU237D, LEU245C, LEU245D, LEU42C, LEU42D, LEU53C, LEU53D, LEU56C, LEU56D, LEU59C, LEU59D, LEU95C, LEU95D, LYS102C, LYS102D, LYS130C, LYS130D, LYS240C, LYS240D, LYS67C, LYS67D, PHE104C, PHE104D, PHE121C, PHE121D, PHE232C, PHE232D, PHE43C, PHE43D, PHE48C, PHE48D, PRO119C, PRO119D, PRO234C, PRO234D, PRO235C, PRO235D, PRO249C, PRO249D, PRO70C, PRO70D, PRO71C, PRO71D, SER247C, SER49C, SER49D, SER60C, THR122C, THR122D, THR126C, THR126D, THR251C, THR251D, THR63C, THR63D, THR72C, THR72D, TYR106C, TYR106D, TYR248C, TYR248D, TYR46C, TYR46D, VAL125C, VAL125D, VAL233C, VAL233D, VAL254C, VAL254D, VAL50C, VAL50D, VAL96C, VAL96D
• C-E: ALA236C, ARG115E, ASN117E, ASN44C, GLN129E, GLN242C, GLN47C, GLU45C, LYS130E, LYS239C, LYS240C, THR122E, THR126E, TYR46C, VAL125E
• C-F: ASN44C, ASN44F, GLN40C, GLN40F, GLN47C, GLN47F, GLU41C, GLU41F, GLU45C, GLU45F, LYS240C, LYS240F, TYR241F, TYR46C, TYR46F
• D-E: ARG115D, ARG115E, ASP132D, ASP132E, CYS128D, CYS128E, GLN107D, GLN107E, GLN127D, GLN127E, GLN129D, GLN129E, GLU138D, GLU138E, GLU142D, GLU142E, GLU148D, GLU148E, GLU151D, GLU151E, GLY123D, GLY123E, GLY137D, GLY137E, ILE110D, ILE110E, ILE133D, ILE133E, LEU136D, LEU136E, LEU149D, LEU149E, LYS102D, LYS102E, LYS130D, LYS130E, LYS76D, LYS76E, PHE135D, PHE135E, PRO108D, PRO108E, PRO134D, PRO134E, PRO140D, PRO140E, PRO141D, PRO141E, PRO78D, PRO78E, SER77D, SER77E, THR109D, THR109E, THR122D, THR122E, THR126D, THR126E, THR80D, THR80E, TYR111D, TYR111E, TYR150D, TYR150E, VAL125D, VAL125E, VAL146D, VAL146E
• D-F: ALA236F, ARG115D, ASN117D, ASN44F, GLN129D, GLN242F, GLN47F, GLU45F, LYS130D, LYS239F, LYS240F, THR122D, THR126D, TYR46F, VAL125D
• E-F: ALA236E, ALA236F, ALA57E, ALA57F, ALA62E, ALA62F, ALA64E, ALA64F, ALA66E, ALA66F, ALA68E, ALA68F, ARG231E, ARG231F, ARG99E, ARG99F, ASN44E, ASN44F, ASP132E, ASP132F, ASP250E, ASP250F, ASP51E, ASP51F, CYS128E, CYS128F, CYS253E, CYS253F, GLN127E, GLN127F, GLN129E, GLN129F, GLN47E, GLN47F, GLN52E, GLN52F, GLU238E, GLU238F, GLU252E, GLU252F, GLU41E, GLU41F, GLU45E, GLU45F, GLU55E, GLU55F, GLY105E, GLY105F, GLY123E, GLY123F, GLY230E, GLY230F, HIS100E, HIS100F, ILE133E, ILE133F, ILE65E, ILE65F, LEU101E, LEU101F, LEU103E, LEU103F, LEU120E, LEU120F, LEU124E, LEU124F, LEU237E, LEU237F, LEU245E, LEU245F, LEU42E, LEU42F, LEU53E, LEU53F, LEU56E, LEU56F, LEU59E, LEU59F, LEU95E, LEU95F, LYS102E, LYS102F, LYS130E, LYS130F, LYS240E, LYS240F, LYS67E, LYS67F, PHE104E, PHE104F, PHE121E, PHE121F, PHE232E, PHE232F, PHE43E, PHE43F, PHE48E, PHE48F, PRO119E, PRO119F, PRO234E, PRO234F, PRO235E, PRO235F, PRO249E, PRO249F, PRO70E, PRO70F, PRO71E, PRO71F, SER247F, SER49E, SER49F, THR122E, THR122F, THR126E, THR126F, THR251E, THR251F, THR63E, THR63F, THR72E, THR72F, TYR106E, TYR106F, TYR248E, TYR248F, TYR46E, TYR46F, VAL125E, VAL125F, VAL233E, VAL233F, VAL254E, VAL254F, VAL50E, VAL50F, VAL96E, VAL96F