2DFS

3-d structure of myosin-v inhibited state

• Total interactions analyzed: 91
• Total true interactions: 26
• Strongest Interaction:
  • Chains: M-S
  • Int. Res.: 105
  • Norm. En. per Res.: -7.3341
• Hub Node: A(8)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-80.398	-160.9283	-353.115	-594.4412	114	23	9	14741	15	50	40
A-C	-68.0582	-200.7254	-367.775	-636.5585	103	12	9	14253	12	58	28
A-D	-98.4927	-72.6731	-337.718	-508.8839	98	21	9	14202	6	43	28
A-E	-20.4628	-75.0133	-374.992	-470.4681	105	21	9	15507	7	36	25
A-F	-56.7448	-77.7764	-328.68	-463.2012	94	21	5	13503	4	54	40
A-G	-93.8274	-164.1325	-586.108	-844.0678	131	85	16	21099	13	61	38
A-M	-98.748	-51.2222	-365.12	-515.0901	197	26	27	19846	17	128	128
A-S	-12.0433	0.0	-5.7865	-17.8298	8	0	0	244	2	3	1
B-C	-12.815	-27.6608	-113.173	-153.6488	38	11	1	4440	3	20	19
C-D	0.0	0.0	-4.978	-4.978	12	0	0	193	0	9	6
D-E	0.0	-3.1845	-25.3154	-28.4999	21	2	1	1321	0	9	8
E-F	0.0	0.0	-1.828	-1.828	10	0	0	153	0	11	8
F-G	-18.5883	-3.2344	-40.3853	-62.208	24	3	1	1767	2	11	10
G-M	-18.6623	8.1813	-104.158	-114.639	33	11	0	3750	0	3	6
G-S	-4.5446	-23.5502	-68.1128	-96.2076	44	1	1	3127	0	21	16
M-N	-60.9922	-153.8795	-335.188	-550.0597	115	23	6	14566	15	51	38
M-O	-76.5466	-191.2929	-373.463	-641.3025	107	19	9	14798	14	57	28
M-P	-88.5833	-107.382	-349.287	-545.2524	96	28	8	14407	7	44	29
M-Q	-26.8186	-81.6439	-406.155	-514.6175	104	20	9	15806	6	38	26
M-R	-50.1839	-64.724	-318.426	-433.3339	94	22	5	13232	5	55	39
M-S	-99.4072	-190.4202	-480.254	-770.0815	105	67	15	17794	14	63	36
N-O	-28.4372	-13.8748	-119.131	-161.4431	43	12	1	4546	3	20	20
O-P	0.0	0.0	-4.9723	-4.9723	14	0	0	220	0	11	11
P-Q	0.0	-6.0235	-21.4661	-27.4896	22	3	1	1338	0	8	8
Q-R	0.0	0.0	-2.2479	-2.2479	13	0	0	171	0	12	8
R-S	-7.1229	-3.2668	-42.4346	-52.8242	25	1	1	1859	0	10	10

Interface residues

• A-B: ALA10B, ALA147B, ALA15B, ALA46B, ALA764A, ALA769A, ALA770A, ALA793A, ALA794A, ALA88B, ARG106B, ARG37B, ARG712A, ARG763A, ARG768A, ARG773A, ARG779A, ARG784A, ARG789A, ARG791A, ARG792A, ARG86B, ARG90B, ASN111B, ASN42B, ASP30A, ASP765A, ASP78B, ASP80B, ASP93B, CYS771A, GLN143B, GLN41B, GLN49B, GLN775A, GLU104B, GLU114B, GLU120B, GLU123B, GLU14B, GLU45B, GLU47B, GLU82B, GLU83B, GLU84B, GLU87B, GLY113B, GLY33B, GLY40B, GLY780A, HIS107B, ILE100B, ILE772A, ILE774A, ILE778A, ILE795A, ILE85B, LEU105B, LEU112B, LEU116B, LEU18B, LEU39B, LEU48B, LEU714A, LEU767A, LEU782A, LYS115B, LYS13B, LYS148B, LYS21B, LYS716A, LYS766A, LYS776A, LYS785A, LYS786A, LYS94B, LYS9A, MET109B, MET124B, MET144B, MET145B, MET36B, MET715A, MET783A, MET788A, MET790A, PHE12B, PHE141B, PHE16B, PHE19B, PHE89B, PHE92B, PRO43B, SER17B, SER38B, SER81B, THR110B, THR117B, THR146B, THR34B, THR44B, THR777A, THR79B, THR8A, TRP781A, TYR10A, TYR138B, TYR787A, VAL108B, VAL121B, VAL142B, VAL35B, VAL713A, VAL91B
• A-C: ALA10C, ALA147C, ALA15C, ALA46C, ALA793A, ALA794A, ALA806A, ALA810A, ALA88C, ARG106C, ARG126C, ARG37C, ARG789A, ARG791A, ARG792A, ARG799A, ARG802A, ARG807A, ARG814A, ARG815A, ARG817A, ARG86C, ARG90C, ASN111C, ASN42C, ASP118C, ASP122C, ASP80C, CYS808A, GLN143C, GLN41C, GLN798A, GLN805A, GLU114C, GLU119C, GLU11C, GLU120C, GLU123C, GLU127C, GLU14C, GLU45C, GLU47C, GLU82C, GLU83C, GLU84C, GLU87C, GLY113C, GLY33C, GLY40C, GLY803A, HIS107C, HIS804A, ILE125C, ILE795A, ILE797A, ILE85C, LEU105C, LEU112C, LEU116C, LEU18C, LEU39C, LEU813A, LYS115C, LYS13C, LYS148C, LYS21C, LYS786A, MET109C, MET124C, MET144C, MET145C, MET36C, MET790A, PHE12C, PHE141C, PHE16C, PHE19C, PHE812A, PHE89C, PHE92C, PRO43C, SER17C, SER38C, SER81C, THR110C, THR117C, THR146C, THR34C, THR44C, THR796A, THR79C, THR811A, THR816A, TYR138C, TYR787A, TYR800A, TYR809A, VAL108C, VAL121C, VAL142C, VAL35C, VAL801A, VAL91C
• A-D: ALA147D, ALA15D, ALA46D, ALA810A, ALA818A, ALA819A, ALA88D, ARG106D, ARG37D, ARG814A, ARG815A, ARG817A, ARG827A, ARG832A, ARG834A, ARG839A, ARG86D, ARG90D, ASN111D, ASN42D, ASP118D, ASP20D, ASP93D, GLN41D, GLN823A, GLN826A, GLN836A, GLU104D, GLU114D, GLU120D, GLU123D, GLU14D, GLU31D, GLU45D, GLU47D, GLU82D, GLU83D, GLU84D, GLU87D, GLY113D, GLY33D, GLY40D, HIS107D, ILE100D, ILE125D, ILE820A, ILE821A, ILE822A, ILE843A, ILE85D, LEU105D, LEU112D, LEU116D, LEU18D, LEU39D, LEU48D, LEU813A, LYS115D, LYS148D, LYS21D, LYS824A, LYS833A, LYS94D, MET109D, MET124D, MET144D, MET145D, MET36D, MET828A, MET838A, PHE12D, PHE141D, PHE19D, PHE812A, PHE825A, PHE89D, PHE92D, PRO43D, SER38D, SER81D, THR110D, THR117D, THR146D, THR34D, THR44D, THR811A, THR816A, THR842A, TYR138D, TYR829A, TYR835A, VAL108D, VAL121D, VAL142D, VAL35D, VAL830A, VAL831A, VAL91D
• A-E: ALA128E, ALA147E, ALA15E, ALA46E, ALA841A, ALA844A, ALA847A, ALA88E, ARG106E, ARG126E, ARG37E, ARG834A, ARG839A, ARG850A, ARG855A, ARG863A, ARG86E, ARG90E, ASN111E, ASN42E, ASN856A, ASP118E, ASP122E, ASP20E, ASP840A, CYS837A, GLN143E, GLN41E, GLN836A, GLN846A, GLN859A, GLU114E, GLU119E, GLU11E, GLU120E, GLU123E, GLU127E, GLU14E, GLU31E, GLU45E, GLU82E, GLU83E, GLU84E, GLU864A, GLU87E, GLY113E, GLY33E, GLY40E, GLY851A, HIS107E, HIS865A, ILE100E, ILE125E, ILE843A, ILE85E, LEU105E, LEU112E, LEU116E, LEU18E, LEU39E, LEU48E, LEU845A, LEU848A, LEU849A, LEU853A, LEU862A, LYS115E, LYS148E, LYS21E, LYS833A, LYS857A, LYS866A, MET109E, MET124E, MET144E, MET145E, MET36E, MET838A, MET860A, MET861A, PHE12E, PHE141E, PHE16E, PHE19E, PHE89E, PHE92E, PRO43E, SER17E, SER38E, THR110E, THR117E, THR146E, THR34E, THR44E, THR842A, TYR138E, TYR835A, TYR852A, TYR858A, VAL108E, VAL121E, VAL142E, VAL35E, VAL854A, VAL91E
• A-F: ALA147F, ALA15F, ALA46F, ALA879A, ALA88F, ARG106F, ARG37F, ARG863A, ARG86F, ARG875A, ARG880A, ARG90F, ASN111F, ASN42F, ASP93F, ASP95F, GLN143F, GLN41F, GLN859A, GLN871A, GLU104F, GLU114F, GLU120F, GLU123F, GLU14F, GLU31F, GLU45F, GLU47F, GLU82F, GLU83F, GLU864A, GLU87F, GLY113F, GLY33F, GLY40F, GLY876A, HIS107F, HIS865A, HIS873A, HIS882A, HIS884A, ILE100F, ILE85F, ILE868A, ILE869A, ILE870A, ILE890A, LEU105F, LEU112F, LEU116F, LEU18F, LEU39F, LEU48F, LEU862A, LEU878A, LEU887A, LYS115F, LYS148F, LYS21F, LYS866A, LYS872A, LYS94F, MET109F, MET124F, MET144F, MET145F, MET36F, MET860A, MET861A, PHE141F, PHE19F, PHE89F, PHE92F, PRO43F, SER17F, SER38F, SER867A, THR110F, THR117F, THR146F, THR34F, THR44F, THR886A, TRP877A, TYR138F, TYR858A, TYR883A, VAL108F, VAL121F, VAL142F, VAL35F, VAL874A, VAL881A, VAL91F
• A-G: ALA10G, ALA128G, ALA147G, ALA15G, ALA46G, ALA57G, ALA889A, ALA88G, ALA902A, ARG106G, ARG126G, ARG37G, ARG86G, ARG885A, ARG898A, ARG899A, ARG904A, ARG90G, ASN111G, ASN42G, ASN53G, ASN60G, ASN952A, ASN953A, ASP122G, ASP20G, ASP56G, ASP58G, CYS895A, CYS896A, GLN143G, GLN41G, GLN49G, GLN894A, GLU114G, GLU119G, GLU11G, GLU120G, GLU123G, GLU127G, GLU14G, GLU31G, GLU45G, GLU47G, GLU54G, GLU67G, GLU82G, GLU83G, GLU84G, GLU87G, GLU905A, GLU955A, GLY113G, GLY33G, GLY40G, GLY59G, GLY61G, HIS107G, HIS882A, ILE100G, ILE125G, ILE27G, ILE52G, ILE63G, ILE85G, ILE890A, ILE956A, LEU105G, LEU112G, LEU116G, LEU18G, LEU32G, LEU39G, LEU48G, LEU887A, LEU893A, LEU906A, LEU909A, LEU954A, LYS115G, LYS13G, LYS148G, LYS21G, LYS75G, LYS888A, LYS903A, LYS907A, LYS908A, MET109G, MET124G, MET144G, MET145G, MET36G, MET51G, MET71G, MET900A, MET901A, MET951A, PHE12G, PHE141G, PHE16G, PHE19G, PHE65G, PHE68G, PHE89G, PHE92G, PRO43G, SER17G, SER38G, SER81G, THR110G, THR117G, THR146G, THR29G, THR34G, THR44G, THR62G, THR79G, THR886A, TYR138G, TYR892A, TYR897A, TYR958A, VAL108G, VAL121G, VAL142G, VAL35G, VAL55G, VAL881A, VAL891A, VAL91G
• A-M: ALA1014A, ALA1014M, ALA1050A, ALA1050M, ALA979A, ALA979M, ALA982A, ALA982M, ARG1044A, ARG1044M, ARG1045A, ARG1045M, ARG1076A, ARG1076M, ARG1078A, ARG1078M, ARG966A, ARG966M, ARG971A, ARG971M, ARG973A, ARG973M, ARG985A, ARG985M, ARG997A, ARG997M, ASN1032A, ASN1032M, ASN1043A, ASN1043M, ASN1073A, ASN1073M, ASN953M, ASN981A, ASN981M, ASP1048A, ASP1048M, ASP1071M, ASP1074A, ASP1074M, ASP968A, ASP968M, GLN1004A, GLN1004M, GLN1031A, GLN1031M, GLN1049A, GLN1049M, GLN1067A, GLN1067M, GLN1080A, GLN1080M, GLN990A, GLN990M, GLU1006A, GLU1006M, GLU1011A, GLU1011M, GLU1020A, GLU1020M, GLU1027A, GLU1027M, GLU1030M, GLU1038A, GLU1038M, GLU1040A, GLU1040M, GLU1041A, GLU1041M, GLU1052A, GLU1052M, GLU1055A, GLU1055M, GLU1063A, GLU1063M, GLU1069A, GLU1069M, GLU955A, GLU955M, GLU961A, GLU961M, GLU970M, GLU976A, GLU976M, GLU977M, GLU978A, GLU978M, GLU992A, GLU992M, GLU999A, GLU999M, HIS1047A, HIS1047M, ILE1010A, ILE1010M, ILE1046A, ILE1046M, ILE1053A, ILE1053M, ILE956M, ILE993A, ILE993M, LEU1000A, LEU1000M, LEU1024A, LEU1024M, LEU1028A, LEU1028M, LEU1034A, LEU1034M, LEU1035A, LEU1035M, LEU1042A, LEU1042M, LEU1070A, LEU1070M, LEU1072A, LEU1072M, LEU1077A, LEU1077M, LEU954A, LEU954M, LEU965A, LEU965M, LEU972A, LEU972M, LEU989A, LEU989M, LEU996A, LEU996M, LYS1007A, LYS1007M, LYS1008A, LYS1008M, LYS1018A, LYS1018M, LYS1029A, LYS1029M, LYS1036A, LYS1036M, LYS1039A, LYS1039M, LYS1051A, LYS1051M, LYS1059A, LYS1059M, LYS1060A, LYS1060M, LYS1066A, LYS1066M, LYS964A, LYS964M, LYS980A, LYS980M, LYS995A, LYS995M, MET1057A, MET1057M, MET951A, MET951M, MET974M, SER959M, SER967A, SER975A, SER975M, SER988A, THR1003A, THR1003M, THR1021A, THR1021M, THR1033A, THR1033M, THR1037A, THR1054A, THR1056A, THR1056M, THR957A, THR957M, THR960A, THR962A, THR962M, THR983A, THR983M, TRP1013A, TRP1013M, TYR1017A, TYR1017M, TYR958A, TYR958M, VAL1025A, VAL1025M, VAL1062A, VAL1062M, VAL969A, VAL969M, VAL986A, VAL986M
• A-S: ALA73S, ARG74S, ASN952A, GLU955A, ILE956A, LYS77S, MET76S, MET951A
• B-C: ALA102C, ALA103C, ALA15B, ARG106C, ARG90C, ASN111C, ASP20B, ASP22B, ASP24B, ASP93C, GLN135C, GLU104C, GLU14B, GLU31B, GLY113C, GLY23B, GLY25B, HIS107C, ILE100C, ILE27B, LEU105C, LEU112C, LEU18B, LYS115C, LYS13B, LYS21B, LYS94C, PHE16B, PHE19B, PHE92C, SER101C, SER17B, THR110C, THR26B, THR28B, THR62B, VAL108C, VAL91C
• C-D: ARG90D, ASP22C, GLU11C, GLU14C, GLY23C, LEU18C, LYS148C, LYS21C, LYS77D, LYS94D, PHE89D, VAL91D
• D-E: ARG90E, ASN111E, ASP20D, ASP22D, ASP24D, GLU114E, GLU14D, GLY113E, GLY23D, HIS107E, LEU112E, LEU18D, LYS115E, LYS13D, LYS21D, PHE16D, PHE19D, PHE92E, SER17D, VAL108E, VAL91E
• E-F: ALA10E, ASP22E, GLU11E, GLU14E, GLY23E, LYS13E, LYS148E, LYS77F, LYS94F, PHE89F
• F-G: ALA103G, ALA15F, ASN111G, ASP20F, ASP22F, ASP24F, GLU104G, GLU14F, GLY113G, GLY23F, GLY25F, HIS107G, LEU112G, LEU18F, LYS115G, LYS13F, LYS21F, LYS94G, PHE16F, PHE19F, PHE92G, SER17F, VAL108G, VAL91G
• G-M: ALA57G, ALA73G, ARG74G, ASN53G, ASN952M, ASN953M, ASP50G, ASP56G, ASP78G, GLN49G, GLU47G, GLU54G, GLU67G, GLU955M, ILE52G, ILE63G, ILE956M, LEU32G, LEU48G, LEU954M, LYS75G, LYS77G, MET36G, MET51G, MET71G, MET72G, MET76G, MET951M, PHE68G, THR70G, THR79G, TYR958M, VAL55G
• G-S: ALA57S, ALA73G, ALA73S, ARG74G, ARG74S, ASN60G, ASN60S, ASP24G, ASP56G, ASP56S, ASP64G, ASP64S, GLU54G, GLU54S, GLU67G, GLU67S, GLY25G, ILE63G, ILE9G, ILE9S, LEU69G, LEU69S, LYS13G, LYS75S, LYS77S, MET71G, MET71S, MET72G, MET72S, MET76G, MET76S, PHE16G, PHE65G, PHE65S, PHE68G, PHE68S, PRO66G, PRO66S, THR26G, THR26S, THR70G, THR70S, VAL55G, VAL55S
• M-N: ALA10N, ALA147N, ALA15N, ALA46N, ALA764M, ALA769M, ALA770M, ALA793M, ALA794M, ALA88N, ARG106N, ARG37N, ARG41M, ARG710M, ARG712M, ARG763M, ARG768M, ARG773M, ARG779M, ARG784M, ARG789M, ARG791M, ARG792M, ARG86N, ARG90N, ASN111N, ASN42N, ASP765M, ASP78N, ASP80N, ASP93N, CYS771M, GLN143N, GLN41N, GLN775M, GLU114N, GLU120N, GLU123N, GLU14N, GLU26M, GLU31N, GLU45N, GLU47N, GLU82N, GLU83N, GLU84N, GLU87N, GLY113N, GLY33N, GLY40N, GLY780M, HIS107N, ILE100N, ILE772M, ILE774M, ILE778M, ILE795M, ILE85N, LEU105N, LEU112N, LEU116N, LEU18N, LEU28M, LEU39N, LEU48N, LEU714M, LEU767M, LEU782M, LYS115N, LYS13N, LYS148N, LYS21N, LYS716M, LYS766M, LYS776M, LYS785M, LYS786M, LYS94N, LYS9M, MET109N, MET124N, MET144N, MET145N, MET36N, MET783M, MET788M, MET790M, PHE12N, PHE141N, PHE16N, PHE19N, PHE89N, PHE92N, PRO43N, SER17N, SER38N, SER709M, SER81N, THR110N, THR117N, THR146N, THR34N, THR44N, THR777M, THR79N, TRP781M, TYR10M, TYR138N, TYR787M, VAL108N, VAL121N, VAL142N, VAL35N, VAL713M, VAL91N
• M-O: ALA10O, ALA128O, ALA147O, ALA15O, ALA46O, ALA793M, ALA794M, ALA806M, ALA810M, ALA818M, ALA88O, ARG106O, ARG126O, ARG37O, ARG789M, ARG791M, ARG792M, ARG799M, ARG802M, ARG807M, ARG814M, ARG815M, ARG817M, ARG86O, ARG90O, ASN111O, ASN42O, ASP122O, ASP129O, ASP20O, ASP80O, CYS808M, GLN143O, GLN41O, GLN798M, GLN805M, GLU114O, GLU119O, GLU11O, GLU120O, GLU123O, GLU127O, GLU140O, GLU14O, GLU31O, GLU45O, GLU47O, GLU82O, GLU83O, GLU84O, GLU87O, GLY113O, GLY33O, GLY40O, GLY803M, HIS107O, HIS804M, ILE125O, ILE795M, ILE797M, ILE821M, ILE85O, LEU105O, LEU112O, LEU116O, LEU18O, LEU39O, LEU813M, LYS115O, LYS13O, LYS148O, LYS21O, LYS786M, MET109O, MET124O, MET144O, MET145O, MET36O, MET790M, PHE12O, PHE141O, PHE16O, PHE19O, PHE812M, PHE89O, PHE92O, PRO43O, SER17O, SER38O, SER81O, THR110O, THR117O, THR146O, THR34O, THR44O, THR796M, THR811M, THR816M, TYR787M, TYR800M, TYR809M, VAL108O, VAL121O, VAL142O, VAL35O, VAL801M, VAL91O
• M-P: ALA147P, ALA15P, ALA46P, ALA810M, ALA818M, ALA819M, ALA88P, ARG106P, ARG37P, ARG814M, ARG815M, ARG817M, ARG827M, ARG832M, ARG834M, ARG839M, ARG86P, ARG90P, ASN111P, ASN42P, ASP20P, ASP93P, GLN41P, GLN823M, GLN826M, GLN836M, GLU104P, GLU114P, GLU120P, GLU123P, GLU14P, GLU31P, GLU45P, GLU47P, GLU82P, GLU83P, GLU84P, GLU87P, GLY113P, GLY33P, GLY40P, HIS107P, ILE100P, ILE125P, ILE820M, ILE821M, ILE822M, ILE843M, ILE85P, LEU105P, LEU112P, LEU116P, LEU18P, LEU39P, LEU48P, LEU813M, LYS115P, LYS148P, LYS21P, LYS824M, LYS833M, LYS94P, MET109P, MET124P, MET144P, MET145P, MET36P, MET828M, MET838M, PHE141P, PHE19P, PHE812M, PHE825M, PHE89P, PHE92P, PRO43P, SER38P, SER81P, THR110P, THR117P, THR146P, THR34P, THR44P, THR811M, THR816M, THR842M, TYR138P, TYR829M, TYR835M, VAL108P, VAL121P, VAL142P, VAL35P, VAL830M, VAL831M, VAL91P
• M-Q: ALA128Q, ALA147Q, ALA15Q, ALA46Q, ALA841M, ALA844M, ALA847M, ALA88Q, ARG106Q, ARG126Q, ARG37Q, ARG834M, ARG839M, ARG850M, ARG855M, ARG863M, ARG86Q, ARG90Q, ASN111Q, ASN42Q, ASN856M, ASP118Q, ASP122Q, ASP20Q, ASP840M, CYS837M, GLN143Q, GLN41Q, GLN836M, GLN846M, GLN859M, GLU114Q, GLU119Q, GLU11Q, GLU120Q, GLU123Q, GLU127Q, GLU14Q, GLU31Q, GLU45Q, GLU82Q, GLU83Q, GLU84Q, GLU864M, GLU87Q, GLY113Q, GLY33Q, GLY40Q, GLY851M, HIS107Q, HIS865M, ILE100Q, ILE125Q, ILE843M, ILE85Q, LEU105Q, LEU112Q, LEU116Q, LEU18Q, LEU39Q, LEU845M, LEU848M, LEU849M, LEU853M, LEU862M, LYS115Q, LYS148Q, LYS21Q, LYS833M, LYS857M, LYS866M, MET109Q, MET124Q, MET144Q, MET145Q, MET36Q, MET838M, MET860M, MET861M, PHE12Q, PHE141Q, PHE16Q, PHE19Q, PHE89Q, PHE92Q, PRO43Q, SER17Q, SER38Q, THR110Q, THR117Q, THR146Q, THR34Q, THR44Q, THR842M, TYR138Q, TYR835M, TYR852M, TYR858M, VAL108Q, VAL121Q, VAL142Q, VAL35Q, VAL854M, VAL91Q
• M-R: ALA147R, ALA15R, ALA46R, ALA879M, ALA88R, ARG106R, ARG37R, ARG863M, ARG86R, ARG875M, ARG880M, ARG90R, ASN111R, ASN42R, ASP93R, GLN143R, GLN41R, GLN859M, GLN871M, GLU104R, GLU114R, GLU120R, GLU123R, GLU14R, GLU31R, GLU45R, GLU47R, GLU82R, GLU83R, GLU864M, GLU87R, GLY113R, GLY33R, GLY40R, GLY876M, HIS107R, HIS865M, HIS873M, HIS882M, HIS884M, ILE100R, ILE85R, ILE868M, ILE869M, ILE870M, ILE890M, LEU105R, LEU112R, LEU116R, LEU18R, LEU39R, LEU48R, LEU862M, LEU878M, LEU887M, LYS115R, LYS148R, LYS21R, LYS866M, LYS872M, LYS94R, MET109R, MET124R, MET144R, MET145R, MET36R, MET860M, MET861M, PHE141R, PHE19R, PHE89R, PHE92R, PRO43R, SER17R, SER38R, SER867M, THR110R, THR117R, THR146R, THR34R, THR44R, THR886M, TRP877M, TYR138R, TYR858M, TYR883M, VAL108R, VAL121R, VAL142R, VAL35R, VAL874M, VAL881M, VAL891M, VAL91R
• M-S: ALA128S, ALA147S, ALA15S, ALA46S, ALA889M, ALA88S, ALA902M, ARG106S, ARG126S, ARG37S, ARG86S, ARG885M, ARG898M, ARG899M, ARG904M, ARG90S, ASN111S, ASN42S, ASP122S, ASP20S, CYS895M, CYS896M, GLN143S, GLN41S, GLN49S, GLN894M, GLU114S, GLU119S, GLU11S, GLU120S, GLU123S, GLU127S, GLU14S, GLU31S, GLU45S, GLU47S, GLU82S, GLU83S, GLU84S, GLU87S, GLU905M, GLY113S, GLY33S, GLY40S, HIS107S, HIS882M, ILE100S, ILE125S, ILE27S, ILE85S, ILE890M, LEU105S, LEU112S, LEU116S, LEU18S, LEU32S, LEU39S, LEU48S, LEU887M, LEU893M, LEU906M, LEU909M, LYS115S, LYS13S, LYS148S, LYS21S, LYS888M, LYS903M, LYS907M, LYS908M, MET109S, MET124S, MET144S, MET145S, MET36S, MET51S, MET900M, MET901M, PHE12S, PHE141S, PHE16S, PHE19S, PHE65S, PHE68S, PHE89S, PHE92S, PRO43S, SER17S, SER38S, THR110S, THR117S, THR146S, THR34S, THR44S, THR79S, THR886M, TYR892M, TYR897M, VAL108S, VAL121S, VAL142S, VAL35S, VAL881M, VAL891M, VAL91S
• N-O: ALA102O, ALA103O, ALA15N, ARG106O, ARG90O, ASN111O, ASN97O, ASP20N, ASP22N, ASP24N, ASP93O, ASP95O, GLN135O, GLU104O, GLU14N, GLU31N, GLY113O, GLY23N, GLY25N, HIS107O, ILE100O, ILE27N, LEU105O, LEU112O, LEU18N, LYS115O, LYS13N, LYS21N, LYS94O, MET109O, PHE12N, PHE16N, PHE19N, PHE65N, PHE92O, SER101O, SER17N, THR110O, THR26N, THR28N, THR62N, VAL108O, VAL91O
• O-P: ASP22O, ASP24O, ASP78P, GLU11O, GLU14O, GLY23O, LEU18O, LYS148O, LYS21O, LYS77P, LYS94P, PHE89P, SER17O, VAL91P
• P-Q: ARG90Q, ASN111Q, ASP20P, ASP22P, ASP24P, GLU114Q, GLU14P, GLY113Q, GLY23P, HIS107Q, LEU112Q, LEU18P, LYS115Q, LYS13P, LYS21P, PHE16P, PHE19P, PHE92Q, SER17P, THR110Q, VAL108Q, VAL91Q
• Q-R: ALA10Q, ASP22Q, ASP24Q, GLU11Q, GLU14Q, GLY23Q, LYS13Q, LYS148Q, LYS21Q, LYS77R, LYS94R, PHE89R, VAL91R
• R-S: ALA103S, ALA15R, ASN111S, ASP20R, ASP22R, ASP24R, GLU104S, GLU14R, GLU31R, GLY113S, GLY23R, GLY25R, HIS107S, LEU112S, LEU18R, LYS115S, LYS13R, LYS21R, LYS94S, PHE16R, PHE19R, PHE92S, SER17R, VAL108S, VAL91S