2D3C

crystal structure of the maize glutamine synthetase complexed with adp and phosphinothricin phosphate

• Total interactions analyzed: 45
• Total true interactions: 30
• Strongest Interaction:
  • Chains: F-G
  • Int. Res.: 182
  • Norm. En. per Res.: -4.0256
• Hub Node: A(6)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-111.1236	-95.2358	-486.655	-693.0144	180	14	15	20903	7	62	53
A-C	0.0	0.0	-0.0997	-0.0997	2	0	0	8	0	2	2
A-D	-124.6558	-94.2461	-500.023	-718.9249	181	19	15	21195	7	62	54
A-E	0.0	0.0	-0.1373	-0.1373	2	0	0	13	0	2	2
A-F	0.0	0.0	-21.4269	-21.4269	20	0	0	1051	0	0	1
A-I	-23.7655	0.0	-45.6457	-69.4112	34	3	1	1818	0	0	1
B-C	-124.1061	-95.6655	-500.848	-720.6196	181	18	15	21187	7	62	54
B-D	0.0	0.0	-0.1184	-0.1184	2	0	0	9	0	2	2
B-E	0.0	0.0	-0.1402	-0.1402	2	0	0	11	0	2	2
B-I	0.0	0.0	-19.8215	-19.8215	20	0	0	1015	0	0	1
B-J	-24.0112	0.0	-49.2799	-73.2911	34	3	1	1914	0	0	1
C-D	0.0	0.0	-0.143	-0.143	2	0	0	13	0	2	2
C-E	-121.9279	-93.1593	-502.283	-717.3702	183	21	15	21402	8	62	54
C-H	-22.6628	0.0	-45.5553	-68.2181	34	2	1	1831	0	0	1
C-J	0.0	0.0	-20.824	-20.824	20	0	0	1039	0	0	1
D-E	-122.8692	-99.2036	-501.178	-723.2508	182	21	15	21129	6	62	54
D-F	-23.7022	0.0	-42.8769	-66.5791	34	2	1	1775	0	0	1
D-G	0.0	0.0	-22.6289	-22.6289	20	0	0	1078	0	0	1
E-G	-22.1001	0.0	-42.1905	-64.2906	34	2	1	1737	0	0	1
E-H	0.0	0.0	-21.7026	-21.7026	20	0	0	1061	0	0	1
F-G	-131.4126	-94.6903	-506.563	-732.6659	182	19	15	21300	7	62	54
F-H	0.0	0.0	-0.1745	-0.1745	2	0	0	16	0	2	2
F-I	-122.2815	-94.4696	-499.088	-715.8391	183	20	15	21132	6	62	54
F-J	0.0	0.0	-0.14	-0.14	2	0	0	14	0	2	2
G-H	-128.4323	-100.5841	-501.587	-730.6035	183	19	15	21367	7	62	54
G-I	0.0	0.0	-0.1225	-0.1225	2	0	0	12	0	2	2
G-J	0.0	0.0	-0.1382	-0.1382	2	0	0	14	0	2	2
H-I	0.0	0.0	-0.1399	-0.1399	2	0	0	12	0	2	2
H-J	-121.5429	-97.9002	-495.342	-714.7851	180	19	15	21084	7	62	54
I-J	-103.6837	-96.8913	-500.011	-700.5861	180	20	15	21195	7	62	54

Interface residues

• A-B: ALA163A, ALA174A, ALA178A, ALA182A, ALA21B, ALA228A, ALA228B, ALA309A, ALA313A, ALA37B, ALA63B, ALA98B, ARG169A, ARG218B, ARG223A, ARG223B, ARG311A, ARG316A, ARG319A, ARG332A, ARG34B, ARG38B, ARG83A, ARG83B, ARG84A, ARG84B, ASN11B, ASN140B, ASN185A, ASN190A, ASN244A, ASN310A, ASN54B, ASN86B, ASN87B, ASN9A, ASN9B, ASP138B, ASP14B, ASP170A, ASP173A, ASP32B, ASP56B, ASP67B, ASP6B, ASP80A, ASP80B, CYS159A, CYS179A, CYS3B, GLN136B, GLN154A, GLN201A, GLN213A, GLN323A, GLU164A, GLU192A, GLU199A, GLU222B, GLU226A, GLU226B, GLU22B, GLU297A, GLU320A, GLU322A, GLU330A, GLU66B, GLU69B, GLY144A, GLY155A, GLY160A, GLY162A, GLY168A, GLY183A, GLY188A, GLY191A, GLY203A, GLY229A, GLY229B, GLY307A, GLY312A, GLY318A, GLY57B, GLY61B, GLY65B, GLY85A, GLY85B, GLY99B, HIS175A, ILE161A, ILE171A, ILE184A, ILE186A, ILE189A, ILE19B, ILE20B, ILE220A, ILE220B, ILE224A, ILE224B, ILE227A, ILE227B, ILE24B, ILE71B, LEU10B, LEU12B, LEU135B, LEU143A, LEU180A, LEU221B, LEU33B, LEU40B, LEU4A, LEU4B, LEU72B, LEU7B, LYS137B, LYS165A, LYS177A, LYS18B, LYS36B, LYS52B, LYS79A, MET31B, PHE167A, PHE200A, PHE234B, PHE82A, PHE82B, PRO146A, PRO151A, PRO156A, PRO204A, PRO51B, PRO64B, PRO81A, PRO97B, SER13B, SER166A, SER187A, SER205A, SER29B, SER35B, SER58B, SER59B, SER68B, THR15B, THR16B, THR225A, THR225B, THR233B, THR321A, THR39B, THR5A, THR5B, THR60B, THR96B, TRP145A, TRP198A, TRP215B, TRP25B, TRP53B, TYR157A, TYR158A, TYR176A, TYR181A, TYR219B, TYR23B, TYR328A, TYR55B, VAL172A, VAL193A, VAL230B, VAL231B, VAL232B, VAL308A, VAL317A, VAL70B, VAL8A, VAL8B
• A-C: ASP170A, CYS3C
• A-D: ALA163D, ALA174D, ALA178D, ALA182D, ALA21A, ALA228A, ALA228D, ALA309D, ALA313D, ALA37A, ALA63A, ALA98A, ARG169D, ARG218A, ARG223A, ARG223D, ARG311D, ARG316D, ARG319D, ARG332D, ARG34A, ARG38A, ARG83A, ARG83D, ARG84A, ARG84D, ASN11A, ASN140A, ASN185D, ASN190D, ASN244D, ASN310D, ASN54A, ASN86A, ASN87A, ASN9A, ASN9D, ASP138A, ASP14A, ASP170D, ASP173D, ASP32A, ASP56A, ASP67A, ASP6A, ASP80A, ASP80D, CYS159D, CYS179D, CYS3A, GLN136A, GLN154D, GLN201D, GLN213D, GLN323D, GLN62A, GLU164D, GLU192D, GLU199D, GLU222A, GLU226A, GLU226D, GLU22A, GLU297D, GLU320D, GLU322D, GLU330D, GLU66A, GLU69A, GLY144D, GLY155D, GLY160D, GLY162D, GLY168D, GLY183D, GLY188D, GLY191D, GLY203D, GLY229A, GLY229D, GLY307D, GLY312D, GLY318D, GLY57A, GLY61A, GLY65A, GLY85A, GLY85D, GLY99A, HIS175D, ILE161D, ILE171D, ILE184D, ILE186D, ILE189D, ILE19A, ILE20A, ILE220A, ILE220D, ILE224A, ILE224D, ILE227A, ILE227D, ILE24A, ILE71A, LEU10A, LEU12A, LEU135A, LEU143D, LEU180D, LEU221A, LEU33A, LEU40A, LEU4A, LEU4D, LEU72A, LEU7A, LYS137A, LYS165D, LYS177D, LYS18A, LYS36A, LYS52A, LYS79D, MET31A, PHE167D, PHE200D, PHE234A, PHE82A, PHE82D, PRO146D, PRO151D, PRO156D, PRO204D, PRO51A, PRO64A, PRO81D, PRO97A, SER13A, SER166D, SER187D, SER29A, SER35A, SER58A, SER59A, SER68A, THR15A, THR16A, THR225A, THR225D, THR233A, THR321D, THR39A, THR5A, THR5D, THR60A, THR96A, TRP145D, TRP198D, TRP215A, TRP25A, TRP53A, TYR157D, TYR158D, TYR176D, TYR181D, TYR219A, TYR23A, TYR328D, TYR55A, VAL172D, VAL193D, VAL202D, VAL230A, VAL231A, VAL232A, VAL308D, VAL317D, VAL70A, VAL8A, VAL8D
• A-E: ASP170E, CYS3A
• A-F: ASN140A, ASN140F, ASP138A, ASP138F, GLN136A, GLN136F, GLY148A, GLY148F, GLY149A, GLY149F, ILE147A, ILE147F, LYS137A, LYS137F, PRO146A, PRO146F, THR139A, THR139F, TRP141A, TRP141F
• A-I: ASP242A, ASP242I, GLU164A, GLU164I, GLY144A, GLY144I, GLY148A, GLY148I, GLY149A, GLY149I, GLY152A, GLY152I, GLY241A, GLY241I, ILE147A, ILE147I, PHE150A, PHE150I, PHE167A, PHE167I, PRO146A, PRO146I, PRO151A, PRO151I, PRO153A, PRO153I, TRP141A, TRP141I, TRP145A, TRP145I, TRP243A, TRP243I, TYR157A, TYR157I
• B-C: ALA163B, ALA174B, ALA178B, ALA182B, ALA21C, ALA228B, ALA228C, ALA309B, ALA313B, ALA37C, ALA63C, ALA98C, ARG169B, ARG218C, ARG223B, ARG223C, ARG311B, ARG316B, ARG319B, ARG332B, ARG34C, ARG38C, ARG83B, ARG83C, ARG84B, ARG84C, ASN11C, ASN140C, ASN185B, ASN190B, ASN244B, ASN310B, ASN54C, ASN86C, ASN87C, ASN9B, ASN9C, ASP138C, ASP14C, ASP170B, ASP173B, ASP32C, ASP56C, ASP67C, ASP6C, ASP80B, ASP80C, CYS159B, CYS179B, CYS3C, GLN136C, GLN154B, GLN201B, GLN213B, GLN323B, GLN62C, GLU164B, GLU192B, GLU199B, GLU222C, GLU226B, GLU226C, GLU22C, GLU297B, GLU320B, GLU322B, GLU330B, GLU66C, GLU69C, GLY144B, GLY155B, GLY160B, GLY162B, GLY168B, GLY183B, GLY188B, GLY191B, GLY203B, GLY229B, GLY229C, GLY27C, GLY307B, GLY312B, GLY318B, GLY57C, GLY61C, GLY65C, GLY85B, GLY85C, GLY99C, HIS175B, HIS296B, ILE161B, ILE171B, ILE184B, ILE186B, ILE189B, ILE19C, ILE20C, ILE220B, ILE220C, ILE224B, ILE224C, ILE227B, ILE227C, ILE24C, ILE71C, LEU10C, LEU12C, LEU135C, LEU143B, LEU180B, LEU221C, LEU33C, LEU40C, LEU4B, LEU4C, LEU7C, LYS137C, LYS165B, LYS177B, LYS18C, LYS36C, LYS52C, LYS79B, MET31C, PHE167B, PHE200B, PHE234C, PHE82B, PHE82C, PRO146B, PRO151B, PRO156B, PRO204B, PRO51C, PRO64C, PRO81B, PRO97C, SER13C, SER166B, SER187B, SER29C, SER35C, SER58C, SER59C, SER68C, THR15C, THR16C, THR225B, THR225C, THR233C, THR321B, THR39C, THR5B, THR5C, THR60C, THR96C, TRP145B, TRP198B, TRP215C, TRP25C, TRP53C, TYR157B, TYR158B, TYR176B, TYR181B, TYR219C, TYR23C, TYR328B, TYR55C, VAL172B, VAL193B, VAL230C, VAL231C, VAL232C, VAL308B, VAL317B, VAL70C, VAL8B, VAL8C
• B-D: ASP170D, CYS3B
• B-E: ASP170B, CYS3E
• B-I: ASN140B, ASN140I, ASP138B, ASP138I, GLN136B, GLN136I, GLY148B, GLY148I, GLY149B, GLY149I, ILE147B, ILE147I, LYS137B, LYS137I, PRO146B, PRO146I, THR139B, THR139I, TRP141B, TRP141I
• B-J: ASP242B, ASP242J, GLU164B, GLU164J, GLY144B, GLY144J, GLY148B, GLY148J, GLY149B, GLY149J, GLY152B, GLY152J, GLY241B, GLY241J, ILE147B, ILE147J, PHE150B, PHE150J, PHE167B, PHE167J, PRO146B, PRO146J, PRO151B, PRO151J, PRO153B, PRO153J, TRP141B, TRP141J, TRP145B, TRP145J, TRP243B, TRP243J, TYR157B, TYR157J
• C-D: ASP170C, CYS3D
• C-E: ALA163C, ALA174C, ALA178C, ALA182C, ALA21E, ALA228C, ALA228E, ALA309C, ALA313C, ALA37E, ALA63E, ALA98E, ARG169C, ARG218E, ARG223C, ARG223E, ARG311C, ARG316C, ARG319C, ARG332C, ARG34E, ARG38E, ARG83C, ARG83E, ARG84C, ARG84E, ASN11E, ASN140E, ASN185C, ASN190C, ASN244C, ASN310C, ASN54E, ASN86E, ASN87E, ASN9C, ASN9E, ASP138E, ASP14E, ASP170C, ASP173C, ASP32E, ASP56E, ASP67E, ASP6E, ASP80C, ASP80E, CYS159C, CYS179C, CYS3E, GLN136E, GLN154C, GLN201C, GLN213C, GLN323C, GLN62E, GLU164C, GLU192C, GLU199C, GLU222E, GLU226C, GLU226E, GLU22E, GLU297C, GLU320C, GLU322C, GLU330C, GLU66E, GLU69E, GLY144C, GLY155C, GLY160C, GLY162C, GLY168C, GLY183C, GLY188C, GLY191C, GLY203C, GLY229C, GLY229E, GLY27E, GLY307C, GLY312C, GLY318C, GLY57E, GLY61E, GLY65E, GLY85C, GLY85E, GLY99E, HIS175C, HIS296C, ILE161C, ILE171C, ILE184C, ILE186C, ILE189C, ILE19E, ILE20E, ILE220C, ILE220E, ILE224C, ILE224E, ILE227C, ILE227E, ILE24E, ILE71E, LEU10E, LEU12E, LEU135E, LEU143C, LEU180C, LEU221E, LEU33E, LEU40E, LEU4C, LEU4E, LEU72E, LEU7E, LYS137E, LYS165C, LYS177C, LYS18E, LYS36E, LYS52E, LYS79C, MET31E, PHE167C, PHE200C, PHE234E, PHE82C, PHE82E, PRO146C, PRO151C, PRO156C, PRO204C, PRO51E, PRO64E, PRO81C, PRO97E, SER13E, SER166C, SER187C, SER205C, SER29E, SER35E, SER58E, SER59E, SER68E, THR15E, THR16E, THR225C, THR225E, THR233E, THR321C, THR39E, THR5C, THR5E, THR60E, THR96E, TRP145C, TRP198C, TRP215E, TRP25E, TRP53E, TYR157C, TYR158C, TYR176C, TYR181C, TYR219E, TYR23E, TYR328C, TYR55E, VAL172C, VAL193C, VAL230E, VAL231E, VAL232E, VAL308C, VAL317C, VAL70E, VAL8C, VAL8E
• C-H: ASP242C, ASP242H, GLU164C, GLU164H, GLY144C, GLY144H, GLY148C, GLY148H, GLY149C, GLY149H, GLY152C, GLY152H, GLY241C, GLY241H, ILE147C, ILE147H, PHE150C, PHE150H, PHE167C, PHE167H, PRO146C, PRO146H, PRO151C, PRO151H, PRO153C, PRO153H, TRP141C, TRP141H, TRP145C, TRP145H, TRP243C, TRP243H, TYR157C, TYR157H
• C-J: ASN140C, ASN140J, ASP138C, ASP138J, GLN136C, GLN136J, GLY148C, GLY148J, GLY149C, GLY149J, ILE147C, ILE147J, LYS137C, LYS137J, PRO146C, PRO146J, THR139C, THR139J, TRP141C, TRP141J
• D-E: ALA163E, ALA174E, ALA178E, ALA182E, ALA21D, ALA228D, ALA228E, ALA309E, ALA313E, ALA37D, ALA63D, ALA98D, ARG169E, ARG218D, ARG223D, ARG223E, ARG311E, ARG316E, ARG319E, ARG332E, ARG34D, ARG38D, ARG83D, ARG83E, ARG84D, ARG84E, ASN11D, ASN140D, ASN185E, ASN190E, ASN244E, ASN310E, ASN54D, ASN86D, ASN87D, ASN9D, ASN9E, ASP138D, ASP14D, ASP170E, ASP173E, ASP32D, ASP56D, ASP67D, ASP6D, ASP80D, ASP80E, CYS159E, CYS179E, CYS3D, GLN136D, GLN154E, GLN201E, GLN213E, GLN323E, GLN62D, GLU164E, GLU192E, GLU199E, GLU222D, GLU226D, GLU226E, GLU22D, GLU297E, GLU320E, GLU322E, GLU330E, GLU66D, GLU69D, GLY144E, GLY155E, GLY160E, GLY162E, GLY168E, GLY183E, GLY188E, GLY191E, GLY203E, GLY229D, GLY229E, GLY27D, GLY307E, GLY312E, GLY318E, GLY57D, GLY61D, GLY65D, GLY85D, GLY85E, GLY99D, HIS175E, HIS296E, ILE161E, ILE171E, ILE184E, ILE186E, ILE189E, ILE19D, ILE20D, ILE220D, ILE220E, ILE224D, ILE224E, ILE227D, ILE227E, ILE24D, ILE71D, LEU10D, LEU12D, LEU135D, LEU143E, LEU180E, LEU221D, LEU33D, LEU40D, LEU4D, LEU4E, LEU72D, LEU7D, LYS137D, LYS165E, LYS177E, LYS18D, LYS36D, LYS52D, LYS79E, MET31D, PHE167E, PHE200E, PHE234D, PHE82D, PHE82E, PRO146E, PRO151E, PRO156E, PRO204E, PRO51D, PRO64D, PRO81E, PRO97D, SER13D, SER166E, SER187E, SER29D, SER35D, SER58D, SER59D, SER68D, THR15D, THR16D, THR225D, THR225E, THR233D, THR321E, THR39D, THR5D, THR5E, THR60D, THR96D, TRP145E, TRP198E, TRP215D, TRP25D, TRP53D, TYR157E, TYR158E, TYR176E, TYR181E, TYR219D, TYR23D, TYR328E, TYR55D, VAL172E, VAL193E, VAL230D, VAL231D, VAL232D, VAL308E, VAL317E, VAL70D, VAL8D, VAL8E
• D-F: ASP242D, ASP242F, GLU164D, GLU164F, GLY144D, GLY144F, GLY148D, GLY148F, GLY149D, GLY149F, GLY152D, GLY152F, GLY241D, GLY241F, ILE147D, ILE147F, PHE150D, PHE150F, PHE167D, PHE167F, PRO146D, PRO146F, PRO151D, PRO151F, PRO153D, PRO153F, TRP141D, TRP141F, TRP145D, TRP145F, TRP243D, TRP243F, TYR157D, TYR157F
• D-G: ASN140D, ASN140G, ASP138D, ASP138G, GLN136D, GLN136G, GLY148D, GLY148G, GLY149D, GLY149G, ILE147D, ILE147G, LYS137D, LYS137G, PRO146D, PRO146G, THR139D, THR139G, TRP141D, TRP141G
• E-G: ASP242E, ASP242G, GLU164E, GLU164G, GLY144E, GLY144G, GLY148E, GLY148G, GLY149E, GLY149G, GLY152E, GLY152G, GLY241E, GLY241G, ILE147E, ILE147G, PHE150E, PHE150G, PHE167E, PHE167G, PRO146E, PRO146G, PRO151E, PRO151G, PRO153E, PRO153G, TRP141E, TRP141G, TRP145E, TRP145G, TRP243E, TRP243G, TYR157E, TYR157G
• E-H: ASN140E, ASN140H, ASP138E, ASP138H, GLN136E, GLN136H, GLY148E, GLY148H, GLY149E, GLY149H, ILE147E, ILE147H, LYS137E, LYS137H, PRO146E, PRO146H, THR139E, THR139H, TRP141E, TRP141H
• F-G: ALA163F, ALA174F, ALA178F, ALA182F, ALA21G, ALA228F, ALA228G, ALA309F, ALA313F, ALA37G, ALA63G, ALA98G, ARG169F, ARG218G, ARG223F, ARG223G, ARG311F, ARG316F, ARG319F, ARG332F, ARG34G, ARG38G, ARG83F, ARG83G, ARG84F, ARG84G, ASN11G, ASN140G, ASN185F, ASN190F, ASN244F, ASN310F, ASN54G, ASN86G, ASN87G, ASN9F, ASN9G, ASP138G, ASP14G, ASP170F, ASP173F, ASP32G, ASP56G, ASP67G, ASP6G, ASP80F, ASP80G, CYS159F, CYS179F, CYS3G, GLN136G, GLN154F, GLN201F, GLN213F, GLN323F, GLN62G, GLU129F, GLU164F, GLU192F, GLU199F, GLU222G, GLU226F, GLU226G, GLU22G, GLU297F, GLU320F, GLU322F, GLU330F, GLU66G, GLU69G, GLY144F, GLY155F, GLY160F, GLY162F, GLY168F, GLY183F, GLY188F, GLY191F, GLY203F, GLY229F, GLY229G, GLY27G, GLY307F, GLY312F, GLY318F, GLY57G, GLY61G, GLY65G, GLY85F, GLY85G, GLY99G, HIS175F, ILE161F, ILE171F, ILE184F, ILE186F, ILE189F, ILE19G, ILE20G, ILE220F, ILE220G, ILE224F, ILE224G, ILE227F, ILE227G, ILE24G, ILE71G, LEU10G, LEU12G, LEU135G, LEU143F, LEU180F, LEU221G, LEU33G, LEU40G, LEU4F, LEU4G, LEU72G, LEU7G, LYS137G, LYS165F, LYS177F, LYS18G, LYS36G, LYS52G, LYS79F, MET31G, PHE167F, PHE200F, PHE234G, PHE82F, PHE82G, PRO146F, PRO151F, PRO156F, PRO204F, PRO51G, PRO64G, PRO81F, PRO97G, SER13G, SER166F, SER187F, SER29G, SER35G, SER58G, SER59G, SER68G, THR15G, THR16G, THR225F, THR225G, THR233G, THR321F, THR39G, THR5F, THR5G, THR60G, THR96G, TRP145F, TRP198F, TRP215G, TRP25G, TRP53G, TYR157F, TYR158F, TYR176F, TYR181F, TYR219G, TYR23G, TYR328F, TYR55G, VAL172F, VAL193F, VAL230G, VAL231G, VAL232G, VAL308F, VAL317F, VAL70G, VAL8F, VAL8G
• F-H: ASP170F, CYS3H
• F-I: ALA163I, ALA174I, ALA178I, ALA182I, ALA21F, ALA228F, ALA228I, ALA309I, ALA313I, ALA37F, ALA63F, ALA98F, ARG169I, ARG218F, ARG223F, ARG223I, ARG311I, ARG316I, ARG319I, ARG332I, ARG34F, ARG38F, ARG83F, ARG83I, ARG84F, ARG84I, ASN11F, ASN140F, ASN185I, ASN190I, ASN244I, ASN310I, ASN54F, ASN86F, ASN87F, ASN9F, ASN9I, ASP138F, ASP14F, ASP170I, ASP173I, ASP32F, ASP56F, ASP67F, ASP6F, ASP80F, ASP80I, CYS159I, CYS179I, CYS3F, GLN136F, GLN154I, GLN201I, GLN213I, GLN323I, GLN62F, GLU129I, GLU164I, GLU192I, GLU199I, GLU222F, GLU226F, GLU226I, GLU22F, GLU297I, GLU320I, GLU322I, GLU330I, GLU66F, GLU69F, GLY144I, GLY155I, GLY160I, GLY162I, GLY168I, GLY183I, GLY188I, GLY191I, GLY203I, GLY229F, GLY229I, GLY27F, GLY307I, GLY312I, GLY318I, GLY57F, GLY61F, GLY65F, GLY85F, GLY85I, GLY99F, HIS175I, ILE161I, ILE171I, ILE184I, ILE186I, ILE189I, ILE19F, ILE20F, ILE220F, ILE220I, ILE224F, ILE224I, ILE227F, ILE227I, ILE24F, ILE71F, LEU10F, LEU12F, LEU135F, LEU143I, LEU180I, LEU221F, LEU33F, LEU40F, LEU4F, LEU4I, LEU72F, LEU7F, LYS137F, LYS165I, LYS177I, LYS18F, LYS36F, LYS52F, LYS79I, MET31F, PHE167I, PHE200I, PHE234F, PHE82F, PHE82I, PRO146I, PRO151I, PRO156I, PRO204I, PRO51F, PRO64F, PRO81I, PRO97F, SER13F, SER166I, SER187I, SER29F, SER35F, SER58F, SER59F, SER68F, THR15F, THR16F, THR225F, THR225I, THR233F, THR321I, THR39F, THR5F, THR5I, THR60F, THR96F, TRP145I, TRP198I, TRP215F, TRP25F, TRP53F, TYR157I, TYR158I, TYR176I, TYR181I, TYR219F, TYR23F, TYR328I, TYR55F, VAL172I, VAL193I, VAL202I, VAL230F, VAL231F, VAL232F, VAL308I, VAL317I, VAL70F, VAL8F, VAL8I
• F-J: ASP170J, CYS3F
• G-H: ALA163G, ALA174G, ALA178G, ALA182G, ALA21H, ALA228G, ALA228H, ALA309G, ALA313G, ALA37H, ALA63H, ALA98H, ARG169G, ARG218H, ARG223G, ARG223H, ARG311G, ARG316G, ARG319G, ARG332G, ARG34H, ARG38H, ARG83G, ARG83H, ARG84G, ARG84H, ASN11H, ASN140H, ASN185G, ASN190G, ASN244G, ASN310G, ASN54H, ASN86H, ASN87H, ASN9G, ASN9H, ASP138H, ASP14H, ASP170G, ASP173G, ASP32H, ASP56H, ASP67H, ASP6H, ASP80G, ASP80H, CYS159G, CYS179G, CYS3H, GLN136H, GLN154G, GLN201G, GLN213G, GLN323G, GLN62H, GLU164G, GLU192G, GLU199G, GLU222H, GLU226G, GLU226H, GLU22H, GLU297G, GLU320G, GLU322G, GLU330G, GLU66H, GLU69H, GLY144G, GLY155G, GLY160G, GLY162G, GLY168G, GLY183G, GLY188G, GLY191G, GLY203G, GLY229G, GLY229H, GLY27H, GLY307G, GLY312G, GLY318G, GLY57H, GLY61H, GLY65H, GLY85G, GLY85H, GLY99H, HIS175G, HIS296G, ILE161G, ILE171G, ILE184G, ILE186G, ILE189G, ILE19H, ILE20H, ILE220G, ILE220H, ILE224G, ILE224H, ILE227G, ILE227H, ILE24H, ILE71H, LEU10H, LEU12H, LEU135H, LEU143G, LEU180G, LEU221H, LEU33H, LEU40H, LEU4G, LEU4H, LEU7H, LYS137H, LYS165G, LYS177G, LYS18H, LYS36H, LYS52H, LYS79G, MET31H, PHE167G, PHE200G, PHE234H, PHE82G, PHE82H, PRO146G, PRO151G, PRO156G, PRO204G, PRO51H, PRO64H, PRO81G, PRO97H, SER13H, SER166G, SER187G, SER205G, SER29H, SER35H, SER58H, SER59H, SER68H, THR15H, THR16H, THR225G, THR225H, THR233H, THR321G, THR39H, THR5G, THR5H, THR60H, THR96H, TRP145G, TRP198G, TRP215H, TRP25H, TRP53H, TYR157G, TYR158G, TYR176G, TYR181G, TYR219H, TYR23H, TYR328G, TYR55H, VAL172G, VAL193G, VAL230G, VAL230H, VAL231H, VAL232H, VAL308G, VAL317G, VAL70H, VAL8G, VAL8H
• G-I: ASP170I, CYS3G
• G-J: ASP170G, CYS3J
• H-I: ASP170H, CYS3I
• H-J: ALA163H, ALA174H, ALA178H, ALA182H, ALA21J, ALA228H, ALA228J, ALA309H, ALA313H, ALA37J, ALA63J, ALA98J, ARG169H, ARG218J, ARG223H, ARG223J, ARG311H, ARG316H, ARG319H, ARG332H, ARG34J, ARG38J, ARG83H, ARG83J, ARG84H, ARG84J, ASN11J, ASN140J, ASN185H, ASN190H, ASN244H, ASN310H, ASN54J, ASN86J, ASN87J, ASN9H, ASN9J, ASP138J, ASP14J, ASP170H, ASP173H, ASP32J, ASP56J, ASP67J, ASP6J, ASP80H, ASP80J, CYS159H, CYS179H, CYS3J, GLN136J, GLN154H, GLN201H, GLN213H, GLN323H, GLN62J, GLU164H, GLU192H, GLU199H, GLU222J, GLU226H, GLU226J, GLU22J, GLU297H, GLU320H, GLU322H, GLU330H, GLU66J, GLU69J, GLY144H, GLY155H, GLY160H, GLY162H, GLY168H, GLY183H, GLY188H, GLY191H, GLY203H, GLY229H, GLY229J, GLY307H, GLY312H, GLY318H, GLY57J, GLY61J, GLY65J, GLY85H, GLY85J, GLY99J, HIS175H, HIS296H, ILE161H, ILE171H, ILE184H, ILE186H, ILE189H, ILE19J, ILE20J, ILE220H, ILE220J, ILE224H, ILE224J, ILE227H, ILE227J, ILE24J, ILE71J, LEU10J, LEU12J, LEU135J, LEU143H, LEU180H, LEU221J, LEU33J, LEU40J, LEU4H, LEU4J, LEU7J, LYS137J, LYS165H, LYS177H, LYS18J, LYS36J, LYS52J, LYS79H, MET31J, PHE167H, PHE200H, PHE234J, PHE82H, PHE82J, PRO146H, PRO151H, PRO156H, PRO204H, PRO51J, PRO64J, PRO81H, PRO97J, SER13J, SER166H, SER187H, SER29J, SER35J, SER58J, SER59J, SER68J, THR15J, THR16J, THR225H, THR225J, THR233J, THR321H, THR39J, THR5H, THR5J, THR60J, THR96J, TRP145H, TRP198H, TRP215J, TRP25J, TRP53J, TYR157H, TYR158H, TYR176H, TYR181H, TYR219J, TYR23J, TYR328H, TYR55J, VAL172H, VAL193H, VAL230J, VAL231J, VAL232J, VAL308H, VAL317H, VAL70J, VAL8H, VAL8J
• I-J: ALA163J, ALA174J, ALA178J, ALA182J, ALA21I, ALA228I, ALA228J, ALA309J, ALA313J, ALA37I, ALA63I, ALA98I, ARG169J, ARG218I, ARG223I, ARG223J, ARG311J, ARG316J, ARG319J, ARG332J, ARG34I, ARG38I, ARG83I, ARG83J, ARG84I, ARG84J, ASN11I, ASN140I, ASN185J, ASN190J, ASN244J, ASN310J, ASN54I, ASN86I, ASN87I, ASN9I, ASN9J, ASP138I, ASP14I, ASP170J, ASP173J, ASP32I, ASP56I, ASP67I, ASP6I, ASP80I, ASP80J, CYS159J, CYS179J, CYS3I, GLN136I, GLN154J, GLN201J, GLN213J, GLN323J, GLN62I, GLU164J, GLU192J, GLU199J, GLU222I, GLU226I, GLU226J, GLU22I, GLU297J, GLU320J, GLU322J, GLU330J, GLU66I, GLU69I, GLY144J, GLY155J, GLY160J, GLY162J, GLY168J, GLY183J, GLY188J, GLY191J, GLY203J, GLY229I, GLY229J, GLY307J, GLY312J, GLY318J, GLY57I, GLY61I, GLY65I, GLY85I, GLY85J, GLY99I, HIS175J, HIS296J, ILE161J, ILE171J, ILE184J, ILE186J, ILE189J, ILE19I, ILE20I, ILE220I, ILE220J, ILE224I, ILE224J, ILE227I, ILE227J, ILE24I, ILE71I, LEU10I, LEU12I, LEU135I, LEU143J, LEU180J, LEU221I, LEU33I, LEU40I, LEU4I, LEU4J, LEU7I, LYS137I, LYS165J, LYS177J, LYS18I, LYS36I, LYS52I, LYS79J, MET31I, PHE167J, PHE200J, PHE234I, PHE82I, PHE82J, PRO146J, PRO151J, PRO156J, PRO204J, PRO51I, PRO64I, PRO81J, PRO97I, SER13I, SER166J, SER187J, SER29I, SER35I, SER58I, SER59I, SER68I, THR15I, THR16I, THR225I, THR225J, THR233I, THR321J, THR39I, THR5I, THR5J, THR60I, THR96I, TRP145J, TRP198J, TRP215I, TRP25I, TRP53I, TYR157J, TYR158J, TYR176J, TYR181J, TYR219I, TYR23I, TYR328J, TYR55I, VAL172J, VAL193J, VAL230I, VAL231I, VAL232I, VAL308J, VAL317J, VAL70I, VAL8I, VAL8J